LeishMANIAdb
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Cell division protein ZapB

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Cell division protein ZapB
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HPY4_LEIBR
TriTrypDb:
LbrM.35.4920 , LBRM2903_350060000 *
Length:
128

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4HPY4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HPY4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 112 116 PF00082 0.445
CLV_PCSK_SKI1_1 70 74 PF00082 0.385
DEG_APCC_DBOX_1 69 77 PF00400 0.406
DEG_Nend_Nbox_1 1 3 PF02207 0.598
DOC_CYCLIN_RxL_1 106 119 PF00134 0.412
DOC_MAPK_gen_1 68 75 PF00069 0.392
DOC_MAPK_MEF2A_6 43 52 PF00069 0.402
DOC_USP7_MATH_1 123 127 PF00917 0.384
DOC_USP7_MATH_1 58 62 PF00917 0.602
DOC_WW_Pin1_4 8 13 PF00397 0.443
LIG_14-3-3_CanoR_1 37 45 PF00244 0.420
LIG_14-3-3_CterR_2 125 128 PF00244 0.431
LIG_EH1_1 108 116 PF00400 0.387
LIG_eIF4E_1 109 115 PF01652 0.387
LIG_FHA_2 115 121 PF00498 0.394
LIG_FHA_2 37 43 PF00498 0.442
LIG_NRBOX 68 74 PF00104 0.386
LIG_UBA3_1 7 13 PF00899 0.414
MOD_CDK_SPK_2 8 13 PF00069 0.443
MOD_CK2_1 114 120 PF00069 0.512
MOD_CK2_1 36 42 PF00069 0.432
MOD_GlcNHglycan 39 42 PF01048 0.472
MOD_GlcNHglycan 61 64 PF01048 0.475
MOD_GSK3_1 20 27 PF00069 0.394
MOD_NEK2_1 1 6 PF00069 0.550
MOD_NEK2_1 36 41 PF00069 0.467
MOD_PKA_2 36 42 PF00069 0.421
MOD_Plk_1 95 101 PF00069 0.334
MOD_ProDKin_1 8 14 PF00069 0.441
MOD_SUMO_for_1 105 108 PF00179 0.464
MOD_SUMO_for_1 50 53 PF00179 0.505
MOD_SUMO_for_1 93 96 PF00179 0.371
TRG_DiLeu_BaEn_4 95 101 PF01217 0.415
TRG_DiLeu_BaLyEn_6 3 8 PF01217 0.417
TRG_Pf-PMV_PEXEL_1 116 120 PF00026 0.393
TRG_Pf-PMV_PEXEL_1 74 78 PF00026 0.300

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I6T4 Leptomonas seymouri 84% 100%
A0A0S4JQY9 Bodo saltans 58% 100%
A0A1X0P0D5 Trypanosomatidae 58% 100%
A0A3Q8IJL8 Leishmania donovani 76% 100%
A0A3S5ISR3 Trypanosoma rangeli 60% 100%
A4IDP5 Leishmania infantum 76% 100%
E9ATQ1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 76% 100%
Q4Q0U7 Leishmania major 73% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS