Separase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Separase

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HPX9_LEIBR

TriTrypDb:

LbrM.35.4870 , LBRM2903_350059500

Length:

1240

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005759	mitochondrial matrix	5	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0035770	ribonucleoprotein granule	3	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0099080	supramolecular complex	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HPX9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HPX9

Function

Biological processes
Term	Name	Level	Count
GO:0000959	mitochondrial RNA metabolic process	6	1
GO:0000963	mitochondrial RNA processing	6	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006396	RNA processing	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009894	regulation of catabolic process	4	1
GO:0009987	cellular process	1	1
GO:0010467	gene expression	4	1
GO:0010468	regulation of gene expression	5	1
GO:0010608	post-transcriptional regulation of gene expression	6	1
GO:0016070	RNA metabolic process	5	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031329	regulation of cellular catabolic process	5	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0043487	regulation of RNA stability	3	1
GO:0043488	regulation of mRNA stability	4	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044528	regulation of mitochondrial mRNA stability	5	1
GO:0046483	heterocycle metabolic process	3	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051252	regulation of RNA metabolic process	5	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0061013	regulation of mRNA catabolic process	6	1
GO:0065007	biological regulation	1	1
GO:0065008	regulation of biological quality	2	1
GO:0071704	organic substance metabolic process	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0090304	nucleic acid metabolic process	4	1
GO:0140053	mitochondrial gene expression	5	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1903311	regulation of mRNA metabolic process	6	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1219	1223	PF00656	0.685
CLV_C14_Caspase3-7	386	390	PF00656	0.571
CLV_C14_Caspase3-7	52	56	PF00656	0.526
CLV_C14_Caspase3-7	60	64	PF00656	0.518
CLV_C14_Caspase3-7	721	725	PF00656	0.542
CLV_C14_Caspase3-7	739	743	PF00656	0.489
CLV_C14_Caspase3-7	756	760	PF00656	0.561
CLV_MEL_PAP_1	710	716	PF00089	0.461
CLV_NRD_NRD_1	1196	1198	PF00675	0.336
CLV_NRD_NRD_1	594	596	PF00675	0.576
CLV_NRD_NRD_1	7	9	PF00675	0.586
CLV_PCSK_KEX2_1	1196	1198	PF00082	0.336
CLV_PCSK_KEX2_1	139	141	PF00082	0.334
CLV_PCSK_KEX2_1	323	325	PF00082	0.486
CLV_PCSK_KEX2_1	594	596	PF00082	0.432
CLV_PCSK_KEX2_1	7	9	PF00082	0.586
CLV_PCSK_PC1ET2_1	139	141	PF00082	0.330
CLV_PCSK_PC1ET2_1	323	325	PF00082	0.353
CLV_PCSK_SKI1_1	1115	1119	PF00082	0.468
CLV_PCSK_SKI1_1	1174	1178	PF00082	0.367
CLV_PCSK_SKI1_1	163	167	PF00082	0.403
CLV_PCSK_SKI1_1	317	321	PF00082	0.288
CLV_PCSK_SKI1_1	629	633	PF00082	0.354
CLV_Separin_Metazoa	716	720	PF03568	0.504
DEG_COP1_1	537	545	PF00400	0.349
DEG_COP1_1	60	68	PF00400	0.529
DEG_Nend_Nbox_1	1	3	PF02207	0.573
DEG_SPOP_SBC_1	761	765	PF00917	0.630
DOC_CDC14_PxL_1	62	70	PF14671	0.526
DOC_CDC14_PxL_1	832	840	PF14671	0.454
DOC_CKS1_1	1056	1061	PF01111	0.397
DOC_CKS1_1	1094	1099	PF01111	0.449
DOC_CKS1_1	349	354	PF01111	0.501
DOC_CYCLIN_RxL_1	314	321	PF00134	0.283
DOC_CYCLIN_RxL_1	780	793	PF00134	0.426
DOC_CYCLIN_yCln2_LP_2	423	429	PF00134	0.422
DOC_MAPK_gen_1	1038	1046	PF00069	0.375
DOC_MAPK_gen_1	1112	1120	PF00069	0.286
DOC_MAPK_gen_1	847	855	PF00069	0.425
DOC_MAPK_MEF2A_6	1038	1046	PF00069	0.375
DOC_MAPK_MEF2A_6	1112	1120	PF00069	0.286
DOC_PP1_RVXF_1	827	834	PF00149	0.374
DOC_PP2B_LxvP_1	122	125	PF13499	0.529
DOC_PP4_FxxP_1	1094	1097	PF00568	0.464
DOC_PP4_FxxP_1	210	213	PF00568	0.407
DOC_PP4_FxxP_1	37	40	PF00568	0.578
DOC_PP4_FxxP_1	618	621	PF00568	0.409
DOC_USP7_MATH_1	1179	1183	PF00917	0.448
DOC_USP7_MATH_1	1223	1227	PF00917	0.552
DOC_USP7_MATH_1	40	44	PF00917	0.600
DOC_USP7_MATH_1	474	478	PF00917	0.417
DOC_USP7_MATH_1	524	528	PF00917	0.539
DOC_USP7_MATH_1	682	686	PF00917	0.403
DOC_USP7_MATH_1	723	727	PF00917	0.510
DOC_USP7_MATH_1	74	78	PF00917	0.652
DOC_USP7_MATH_1	740	744	PF00917	0.542
DOC_USP7_MATH_1	761	765	PF00917	0.736
DOC_USP7_MATH_1	79	83	PF00917	0.627
DOC_USP7_MATH_1	802	806	PF00917	0.412
DOC_USP7_MATH_1	891	895	PF00917	0.573
DOC_USP7_MATH_1	997	1001	PF00917	0.322
DOC_WW_Pin1_4	103	108	PF00397	0.537
DOC_WW_Pin1_4	1055	1060	PF00397	0.407
DOC_WW_Pin1_4	1093	1098	PF00397	0.465
DOC_WW_Pin1_4	1129	1134	PF00397	0.383
DOC_WW_Pin1_4	120	125	PF00397	0.354
DOC_WW_Pin1_4	305	310	PF00397	0.324
DOC_WW_Pin1_4	348	353	PF00397	0.498
DOC_WW_Pin1_4	410	415	PF00397	0.546
DOC_WW_Pin1_4	563	568	PF00397	0.406
DOC_WW_Pin1_4	921	926	PF00397	0.549
DOC_WW_Pin1_4	962	967	PF00397	0.350
LIG_14-3-3_CanoR_1	1051	1057	PF00244	0.394
LIG_14-3-3_CanoR_1	1123	1128	PF00244	0.342
LIG_14-3-3_CanoR_1	140	145	PF00244	0.447
LIG_14-3-3_CanoR_1	31	40	PF00244	0.566
LIG_14-3-3_CanoR_1	317	323	PF00244	0.290
LIG_14-3-3_CanoR_1	719	723	PF00244	0.546
LIG_14-3-3_CanoR_1	783	789	PF00244	0.357
LIG_14-3-3_CanoR_1	8	14	PF00244	0.655
LIG_14-3-3_CanoR_1	83	89	PF00244	0.607
LIG_14-3-3_CanoR_1	847	855	PF00244	0.359
LIG_Actin_WH2_2	131	148	PF00022	0.466
LIG_Actin_WH2_2	55	71	PF00022	0.530
LIG_Actin_WH2_2	703	721	PF00022	0.476
LIG_AP2alpha_2	425	427	PF02296	0.393
LIG_APCC_ABBA_1	221	226	PF00400	0.445
LIG_APCC_ABBA_1	796	801	PF00400	0.489
LIG_APCC_ABBAyCdc20_2	512	518	PF00400	0.410
LIG_BRCT_BRCA1_1	1181	1185	PF00533	0.410
LIG_BRCT_BRCA1_1	243	247	PF00533	0.374
LIG_BRCT_BRCA1_1	702	706	PF00533	0.477
LIG_BRCT_BRCA1_1	964	968	PF00533	0.409
LIG_CaM_IQ_9	800	816	PF13499	0.351
LIG_Clathr_ClatBox_1	222	226	PF01394	0.447
LIG_Clathr_ClatBox_1	399	403	PF01394	0.462
LIG_Clathr_ClatBox_1	865	869	PF01394	0.301
LIG_CSL_BTD_1	564	567	PF09270	0.406
LIG_FHA_1	1157	1163	PF00498	0.306
LIG_FHA_1	133	139	PF00498	0.315
LIG_FHA_1	174	180	PF00498	0.366
LIG_FHA_1	190	196	PF00498	0.417
LIG_FHA_1	198	204	PF00498	0.334
LIG_FHA_1	214	220	PF00498	0.413
LIG_FHA_1	257	263	PF00498	0.334
LIG_FHA_1	33	39	PF00498	0.579
LIG_FHA_1	359	365	PF00498	0.319
LIG_FHA_1	394	400	PF00498	0.423
LIG_FHA_1	404	410	PF00498	0.430
LIG_FHA_1	630	636	PF00498	0.379
LIG_FHA_1	819	825	PF00498	0.376
LIG_FHA_1	858	864	PF00498	0.355
LIG_FHA_2	1056	1062	PF00498	0.388
LIG_FHA_2	1167	1173	PF00498	0.391
LIG_FHA_2	1217	1223	PF00498	0.643
LIG_FHA_2	384	390	PF00498	0.405
LIG_FHA_2	50	56	PF00498	0.548
LIG_FHA_2	567	573	PF00498	0.314
LIG_FHA_2	719	725	PF00498	0.553
LIG_FHA_2	730	736	PF00498	0.514
LIG_FHA_2	737	743	PF00498	0.462
LIG_FHA_2	901	907	PF00498	0.355
LIG_FHA_2	922	928	PF00498	0.537
LIG_GBD_Chelix_1	229	237	PF00786	0.453
LIG_GBD_Chelix_1	312	320	PF00786	0.279
LIG_LIR_Apic_2	1055	1059	PF02991	0.405
LIG_LIR_Apic_2	1093	1097	PF02991	0.471
LIG_LIR_Apic_2	35	40	PF02991	0.508
LIG_LIR_Gen_1	1003	1014	PF02991	0.383
LIG_LIR_Gen_1	1040	1050	PF02991	0.370
LIG_LIR_Gen_1	1067	1077	PF02991	0.375
LIG_LIR_Gen_1	1114	1124	PF02991	0.363
LIG_LIR_Gen_1	114	122	PF02991	0.485
LIG_LIR_Gen_1	1141	1151	PF02991	0.381
LIG_LIR_Gen_1	303	312	PF02991	0.381
LIG_LIR_Gen_1	728	738	PF02991	0.470
LIG_LIR_Gen_1	965	976	PF02991	0.317
LIG_LIR_LC3C_4	505	509	PF02991	0.448
LIG_LIR_Nem_3	1003	1009	PF02991	0.394
LIG_LIR_Nem_3	1040	1046	PF02991	0.370
LIG_LIR_Nem_3	1067	1072	PF02991	0.356
LIG_LIR_Nem_3	1114	1120	PF02991	0.363
LIG_LIR_Nem_3	114	118	PF02991	0.572
LIG_LIR_Nem_3	1141	1146	PF02991	0.368
LIG_LIR_Nem_3	1195	1201	PF02991	0.418
LIG_LIR_Nem_3	200	205	PF02991	0.476
LIG_LIR_Nem_3	303	307	PF02991	0.399
LIG_LIR_Nem_3	336	341	PF02991	0.479
LIG_LIR_Nem_3	728	734	PF02991	0.466
LIG_LIR_Nem_3	834	838	PF02991	0.289
LIG_LIR_Nem_3	965	971	PF02991	0.404
LIG_LYPXL_yS_3	835	838	PF13949	0.450
LIG_MYND_2	125	129	PF01753	0.404
LIG_NRBOX	1126	1132	PF00104	0.389
LIG_NRBOX	140	146	PF00104	0.487
LIG_NRBOX	311	317	PF00104	0.364
LIG_NRBOX	780	786	PF00104	0.364
LIG_PCNA_yPIPBox_3	476	488	PF02747	0.468
LIG_Pex14_1	373	377	PF04695	0.366
LIG_Rb_LxCxE_1	437	457	PF01857	0.457
LIG_REV1ctd_RIR_1	1183	1192	PF16727	0.321
LIG_RPA_C_Fungi	576	588	PF08784	0.346
LIG_SH2_CRK	1056	1060	PF00017	0.405
LIG_SH2_CRK	1069	1073	PF00017	0.369
LIG_SH2_CRK	1106	1110	PF00017	0.362
LIG_SH2_CRK	1113	1117	PF00017	0.361
LIG_SH2_CRK	597	601	PF00017	0.411
LIG_SH2_NCK_1	1069	1073	PF00017	0.369
LIG_SH2_NCK_1	1106	1110	PF00017	0.362
LIG_SH2_NCK_1	731	735	PF00017	0.470
LIG_SH2_NCK_1	994	998	PF00017	0.380
LIG_SH2_STAP1	1113	1117	PF00017	0.361
LIG_SH2_STAP1	330	334	PF00017	0.487
LIG_SH2_STAP1	680	684	PF00017	0.402
LIG_SH2_STAP1	827	831	PF00017	0.369
LIG_SH2_STAT3	1180	1183	PF00017	0.382
LIG_SH2_STAT5	137	140	PF00017	0.398
LIG_SH2_STAT5	649	652	PF00017	0.445
LIG_SH2_STAT5	731	734	PF00017	0.624
LIG_SH3_2	980	985	PF14604	0.417
LIG_SH3_3	867	873	PF00018	0.395
LIG_SH3_3	977	983	PF00018	0.412
LIG_SUMO_SIM_anti_2	1098	1104	PF11976	0.427
LIG_SUMO_SIM_anti_2	1189	1195	PF11976	0.308
LIG_SUMO_SIM_anti_2	176	183	PF11976	0.360
LIG_SUMO_SIM_anti_2	361	369	PF11976	0.309
LIG_SUMO_SIM_anti_2	430	437	PF11976	0.319
LIG_SUMO_SIM_anti_2	787	793	PF11976	0.459
LIG_SUMO_SIM_par_1	176	183	PF11976	0.360
LIG_SUMO_SIM_par_1	952	958	PF11976	0.433
LIG_TRAF2_1	1169	1172	PF00917	0.336
LIG_UBA3_1	315	323	PF00899	0.308
LIG_UBA3_1	845	850	PF00899	0.490
LIG_UBA3_1	954	962	PF00899	0.450
LIG_WRC_WIRS_1	1029	1034	PF05994	0.356
LIG_WRC_WIRS_1	246	251	PF05994	0.480
LIG_WRC_WIRS_1	319	324	PF05994	0.295
LIG_WRC_WIRS_1	409	414	PF05994	0.361
MOD_CDK_SPK_2	1055	1060	PF00069	0.407
MOD_CDK_SPxK_1	348	354	PF00069	0.495
MOD_CK1_1	1000	1006	PF00069	0.321
MOD_CK1_1	103	109	PF00069	0.551
MOD_CK1_1	1205	1211	PF00069	0.515
MOD_CK1_1	1228	1234	PF00069	0.646
MOD_CK1_1	130	136	PF00069	0.469
MOD_CK1_1	248	254	PF00069	0.471
MOD_CK1_1	308	314	PF00069	0.437
MOD_CK1_1	418	424	PF00069	0.484
MOD_CK1_1	430	436	PF00069	0.438
MOD_CK1_1	510	516	PF00069	0.496
MOD_CK1_1	528	534	PF00069	0.502
MOD_CK1_1	61	67	PF00069	0.684
MOD_CK1_1	736	742	PF00069	0.562
MOD_CK1_1	774	780	PF00069	0.477
MOD_CK1_1	851	857	PF00069	0.492
MOD_CK2_1	1166	1172	PF00069	0.407
MOD_CK2_1	1223	1229	PF00069	0.609
MOD_CK2_1	438	444	PF00069	0.452
MOD_CK2_1	566	572	PF00069	0.351
MOD_CK2_1	640	646	PF00069	0.405
MOD_CK2_1	729	735	PF00069	0.555
MOD_DYRK1A_RPxSP_1	410	414	PF00069	0.399
MOD_GlcNHglycan	102	106	PF01048	0.790
MOD_GlcNHglycan	1066	1069	PF01048	0.341
MOD_GlcNHglycan	1207	1210	PF01048	0.515
MOD_GlcNHglycan	129	132	PF01048	0.442
MOD_GlcNHglycan	25	28	PF01048	0.725
MOD_GlcNHglycan	418	421	PF01048	0.465
MOD_GlcNHglycan	454	457	PF01048	0.630
MOD_GlcNHglycan	476	479	PF01048	0.515
MOD_GlcNHglycan	483	486	PF01048	0.416
MOD_GlcNHglycan	529	534	PF01048	0.605
MOD_GlcNHglycan	554	557	PF01048	0.553
MOD_GlcNHglycan	672	675	PF01048	0.426
MOD_GlcNHglycan	684	687	PF01048	0.377
MOD_GlcNHglycan	764	767	PF01048	0.689
MOD_GlcNHglycan	773	776	PF01048	0.497
MOD_GlcNHglycan	897	900	PF01048	0.608
MOD_GSK3_1	1000	1007	PF00069	0.480
MOD_GSK3_1	1024	1031	PF00069	0.345
MOD_GSK3_1	1156	1163	PF00069	0.573
MOD_GSK3_1	1205	1212	PF00069	0.535
MOD_GSK3_1	1223	1230	PF00069	0.612
MOD_GSK3_1	19	26	PF00069	0.670
MOD_GSK3_1	238	245	PF00069	0.466
MOD_GSK3_1	329	336	PF00069	0.517
MOD_GSK3_1	337	344	PF00069	0.403
MOD_GSK3_1	358	365	PF00069	0.472
MOD_GSK3_1	383	390	PF00069	0.421
MOD_GSK3_1	410	417	PF00069	0.500
MOD_GSK3_1	430	437	PF00069	0.420
MOD_GSK3_1	438	445	PF00069	0.429
MOD_GSK3_1	447	454	PF00069	0.665
MOD_GSK3_1	49	56	PF00069	0.540
MOD_GSK3_1	524	531	PF00069	0.609
MOD_GSK3_1	559	566	PF00069	0.561
MOD_GSK3_1	573	580	PF00069	0.366
MOD_GSK3_1	723	730	PF00069	0.563
MOD_GSK3_1	736	743	PF00069	0.622
MOD_GSK3_1	853	860	PF00069	0.462
MOD_GSK3_1	891	898	PF00069	0.531
MOD_LATS_1	1076	1082	PF00433	0.294
MOD_N-GLC_1	1231	1236	PF02516	0.618
MOD_N-GLC_1	387	392	PF02516	0.353
MOD_N-GLC_1	771	776	PF02516	0.482
MOD_N-GLC_1	848	853	PF02516	0.352
MOD_NEK2_1	101	106	PF00069	0.555
MOD_NEK2_1	180	185	PF00069	0.370
MOD_NEK2_1	225	230	PF00069	0.427
MOD_NEK2_1	247	252	PF00069	0.479
MOD_NEK2_1	341	346	PF00069	0.466
MOD_NEK2_1	416	421	PF00069	0.687
MOD_NEK2_1	507	512	PF00069	0.445
MOD_NEK2_1	670	675	PF00069	0.480
MOD_NEK2_1	717	722	PF00069	0.441
MOD_NEK2_1	784	789	PF00069	0.477
MOD_NEK2_1	790	795	PF00069	0.411
MOD_NEK2_1	831	836	PF00069	0.317
MOD_NEK2_1	868	873	PF00069	0.391
MOD_NEK2_1	955	960	PF00069	0.440
MOD_NEK2_2	1181	1186	PF00069	0.418
MOD_NEK2_2	149	154	PF00069	0.366
MOD_NEK2_2	318	323	PF00069	0.286
MOD_NEK2_2	900	905	PF00069	0.523
MOD_PIKK_1	1156	1162	PF00454	0.372
MOD_PIKK_1	1166	1172	PF00454	0.377
MOD_PIKK_1	1179	1185	PF00454	0.438
MOD_PIKK_1	25	31	PF00454	0.535
MOD_PIKK_1	282	288	PF00454	0.389
MOD_PIKK_1	387	393	PF00454	0.329
MOD_PIKK_1	434	440	PF00454	0.314
MOD_PIKK_1	488	494	PF00454	0.481
MOD_PIKK_1	684	690	PF00454	0.297
MOD_PIKK_1	740	746	PF00454	0.636
MOD_PIKK_1	818	824	PF00454	0.373
MOD_PIKK_1	881	887	PF00454	0.398
MOD_PK_1	559	565	PF00069	0.355
MOD_PKA_2	274	280	PF00069	0.575
MOD_PKA_2	32	38	PF00069	0.573
MOD_PKA_2	670	676	PF00069	0.483
MOD_PKA_2	712	718	PF00069	0.391
MOD_PKA_2	753	759	PF00069	0.533
MOD_Plk_1	1010	1016	PF00069	0.373
MOD_Plk_1	197	203	PF00069	0.437
MOD_Plk_1	225	231	PF00069	0.574
MOD_Plk_1	238	244	PF00069	0.378
MOD_Plk_1	341	347	PF00069	0.335
MOD_Plk_1	368	374	PF00069	0.432
MOD_Plk_1	383	389	PF00069	0.379
MOD_Plk_1	430	436	PF00069	0.568
MOD_Plk_1	536	542	PF00069	0.460
MOD_Plk_1	727	733	PF00069	0.595
MOD_Plk_1	851	857	PF00069	0.565
MOD_Plk_1	868	874	PF00069	0.291
MOD_Plk_2-3	1172	1178	PF00069	0.419
MOD_Plk_2-3	337	343	PF00069	0.473
MOD_Plk_4	1024	1030	PF00069	0.346
MOD_Plk_4	1123	1129	PF00069	0.454
MOD_Plk_4	1181	1187	PF00069	0.367
MOD_Plk_4	140	146	PF00069	0.454
MOD_Plk_4	173	179	PF00069	0.383
MOD_Plk_4	198	204	PF00069	0.461
MOD_Plk_4	242	248	PF00069	0.439
MOD_Plk_4	308	314	PF00069	0.295
MOD_Plk_4	418	424	PF00069	0.483
MOD_Plk_4	430	436	PF00069	0.321
MOD_Plk_4	537	543	PF00069	0.555
MOD_Plk_4	733	739	PF00069	0.655
MOD_Plk_4	909	915	PF00069	0.361
MOD_ProDKin_1	103	109	PF00069	0.537
MOD_ProDKin_1	1055	1061	PF00069	0.400
MOD_ProDKin_1	1093	1099	PF00069	0.457
MOD_ProDKin_1	1129	1135	PF00069	0.380
MOD_ProDKin_1	120	126	PF00069	0.362
MOD_ProDKin_1	305	311	PF00069	0.320
MOD_ProDKin_1	348	354	PF00069	0.495
MOD_ProDKin_1	410	416	PF00069	0.557
MOD_ProDKin_1	563	569	PF00069	0.403
MOD_ProDKin_1	921	927	PF00069	0.543
MOD_ProDKin_1	962	968	PF00069	0.344
MOD_SUMO_rev_2	61	70	PF00179	0.527
MOD_SUMO_rev_2	626	631	PF00179	0.519
TRG_DiLeu_BaEn_1	1004	1009	PF01217	0.383
TRG_DiLeu_BaEn_1	1098	1103	PF01217	0.345
TRG_DiLeu_BaEn_1	1172	1177	PF01217	0.298
TRG_DiLeu_BaLyEn_6	619	624	PF01217	0.328
TRG_DiLeu_BaLyEn_6	780	785	PF01217	0.359
TRG_DiLeu_BaLyEn_6	841	846	PF01217	0.449
TRG_ENDOCYTIC_2	1069	1072	PF00928	0.358
TRG_ENDOCYTIC_2	1077	1080	PF00928	0.372
TRG_ENDOCYTIC_2	1106	1109	PF00928	0.348
TRG_ENDOCYTIC_2	1113	1116	PF00928	0.369
TRG_ENDOCYTIC_2	1143	1146	PF00928	0.367
TRG_ENDOCYTIC_2	597	600	PF00928	0.404
TRG_ENDOCYTIC_2	731	734	PF00928	0.467
TRG_ENDOCYTIC_2	827	830	PF00928	0.355
TRG_ENDOCYTIC_2	835	838	PF00928	0.374
TRG_ENDOCYTIC_2	880	883	PF00928	0.373
TRG_ER_diArg_1	1048	1051	PF00400	0.382
TRG_ER_diArg_1	1196	1198	PF00400	0.336
TRG_ER_diArg_1	31	34	PF00400	0.580
TRG_ER_diArg_1	594	596	PF00400	0.432
TRG_Pf-PMV_PEXEL_1	1174	1178	PF00026	0.367
TRG_Pf-PMV_PEXEL_1	839	843	PF00026	0.370

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILX8	Leptomonas seymouri	47%	99%
A0A3Q8IRJ1	Leishmania donovani	73%	100%
A4IDP1	Leishmania infantum	73%	100%
E9ATP6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	71%	100%
Q4Q0V2	Leishmania major	72%	100%