Amastin

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Amastin

Gene product:

Amastin surface glycoprotein, putative

Species:

Leishmania braziliensis

UniProt:

A4HPT1_LEIBR

TriTrypDb:

LbrM.35.4370 , LBRM2903_350054300

Length:

144

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

A4HPT1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HPT1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	40	44	PF00082	0.528
CLV_PCSK_SKI1_1	71	75	PF00082	0.320
CLV_PCSK_SKI1_1	97	101	PF00082	0.533
DEG_APCC_DBOX_1	70	78	PF00400	0.520
DEG_Nend_UBRbox_2	1	3	PF02207	0.553
DOC_CYCLIN_RxL_1	94	101	PF00134	0.383
DOC_MAPK_DCC_7	71	79	PF00069	0.583
DOC_MAPK_MEF2A_6	4	12	PF00069	0.531
DOC_MAPK_MEF2A_6	71	79	PF00069	0.520
DOC_PP1_RVXF_1	95	101	PF00149	0.383
DOC_PP2B_LxvP_1	117	120	PF13499	0.383
DOC_USP7_MATH_1	113	117	PF00917	0.383
LIG_BRCT_BRCA1_1	65	69	PF00533	0.416
LIG_EH1_1	133	141	PF00400	0.483
LIG_FHA_1	131	137	PF00498	0.483
LIG_FHA_1	54	60	PF00498	0.483
LIG_LIR_Gen_1	15	25	PF02991	0.525
LIG_LIR_Gen_1	66	77	PF02991	0.402
LIG_LIR_Nem_3	15	21	PF02991	0.472
LIG_LIR_Nem_3	38	42	PF02991	0.353
LIG_LIR_Nem_3	53	58	PF02991	0.249
LIG_LIR_Nem_3	70	76	PF02991	0.451
LIG_MLH1_MIPbox_1	65	69	PF16413	0.483
LIG_PDZ_Class_2	139	144	PF00595	0.395
LIG_Pex14_2	39	43	PF04695	0.353
LIG_Pex14_2	69	73	PF04695	0.541
LIG_Pex14_2	96	100	PF04695	0.383
LIG_REV1ctd_RIR_1	40	48	PF16727	0.383
LIG_REV1ctd_RIR_1	66	74	PF16727	0.483
LIG_SH2_STAT3	29	32	PF00017	0.383
LIG_SH2_STAT5	134	137	PF00017	0.483
LIG_SH3_3	11	17	PF00018	0.408
LIG_SUMO_SIM_par_1	50	56	PF11976	0.446
LIG_TYR_ITIM	16	21	PF00017	0.527
LIG_WRC_WIRS_1	39	44	PF05994	0.383
LIG_WRC_WIRS_1	65	70	PF05994	0.483
MOD_CK1_1	138	144	PF00069	0.483
MOD_CK1_1	50	56	PF00069	0.483
MOD_CK1_1	67	73	PF00069	0.185
MOD_GSK3_1	130	137	PF00069	0.483
MOD_GSK3_1	63	70	PF00069	0.483
MOD_GSK3_1	81	88	PF00069	0.133
MOD_N-GLC_1	23	28	PF02516	0.583
MOD_NEK2_1	135	140	PF00069	0.483
MOD_NEK2_1	63	68	PF00069	0.363
MOD_NEK2_1	81	86	PF00069	0.133
MOD_NEK2_1	87	92	PF00069	0.377
MOD_PIKK_1	23	29	PF00454	0.383
MOD_PK_1	4	10	PF00069	0.534
MOD_Plk_1	23	29	PF00069	0.357
MOD_Plk_4	130	136	PF00069	0.424
MOD_Plk_4	138	144	PF00069	0.358
MOD_Plk_4	50	56	PF00069	0.483
MOD_Plk_4	64	70	PF00069	0.407
TRG_DiLeu_BaLyEn_6	72	77	PF01217	0.483
TRG_ENDOCYTIC_2	105	108	PF00928	0.341
TRG_ENDOCYTIC_2	18	21	PF00928	0.489
TRG_Pf-PMV_PEXEL_1	97	101	PF00026	0.583

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0P3I9	Trypanosomatidae	36%	66%
A0A422NT54	Trypanosoma rangeli	30%	85%