LeishMANIAdb
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FtsX domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
FtsX domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HPR0_LEIBR
TriTrypDb:
LbrM.35.4160 , LBRM2903_350051800
Length:
133

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0016020 membrane 2 10
GO:0110165 cellular anatomical entity 1 10

Expansion

Sequence features

A4HPR0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HPR0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 34 38 PF00082 0.373
CLV_PCSK_SKI1_1 76 80 PF00082 0.448
DEG_APCC_DBOX_1 33 41 PF00400 0.496
DEG_APCC_DBOX_1 75 83 PF00400 0.255
LIG_BRCT_BRCA1_1 46 50 PF00533 0.353
LIG_DCNL_PONY_1 1 4 PF03556 0.435
LIG_EVH1_2 70 74 PF00568 0.411
LIG_FHA_1 51 57 PF00498 0.403
LIG_FHA_1 86 92 PF00498 0.407
LIG_LIR_Nem_3 60 64 PF02991 0.458
LIG_NRBOX 36 42 PF00104 0.444
LIG_Pex14_2 74 78 PF04695 0.423
LIG_REV1ctd_RIR_1 30 38 PF16727 0.552
LIG_SH2_STAT5 123 126 PF00017 0.456
LIG_SUMO_SIM_anti_2 45 53 PF11976 0.355
LIG_SUMO_SIM_anti_2 94 100 PF11976 0.319
LIG_SUMO_SIM_par_1 94 100 PF11976 0.453
LIG_UBA3_1 98 105 PF00899 0.402
LIG_WRC_WIRS_1 58 63 PF05994 0.569
LIG_WRC_WIRS_1 75 80 PF05994 0.399
MOD_CK1_1 127 133 PF00069 0.667
MOD_GlcNHglycan 126 129 PF01048 0.324
MOD_GlcNHglycan 15 18 PF01048 0.328
MOD_GSK3_1 44 51 PF00069 0.313
MOD_GSK3_1 97 104 PF00069 0.439
MOD_NEK2_1 101 106 PF00069 0.531
MOD_NEK2_1 116 121 PF00069 0.525
MOD_NEK2_1 42 47 PF00069 0.340
MOD_NEK2_1 50 55 PF00069 0.352
MOD_NEK2_1 57 62 PF00069 0.410
MOD_NEK2_1 74 79 PF00069 0.378
MOD_Plk_4 23 29 PF00069 0.362
MOD_Plk_4 44 50 PF00069 0.306
MOD_Plk_4 91 97 PF00069 0.362
MOD_SUMO_rev_2 62 71 PF00179 0.275
TRG_DiLeu_BaEn_1 112 117 PF01217 0.599

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IKW4 Leptomonas seymouri 69% 100%
A0A0S4JIM1 Bodo saltans 35% 100%
A0A1X0P3L7 Trypanosomatidae 43% 100%
A0A3S7XBF2 Leishmania donovani 86% 100%
A0A422NKK4 Trypanosoma rangeli 42% 100%
A4ID04 Leishmania infantum 86% 100%
D0A8F5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 93%
E9ATH4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%
Q4Q123 Leishmania major 87% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS