LeishMANIAdb
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Putative 60S ribosomal protein L10a

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative 60S ribosomal protein L10a
Gene product:
60S ribosomal protein L10a, putative
Species:
Leishmania braziliensis
UniProt:
A4HPP4_LEIBR
TriTrypDb:
LbrM.35.4000 , LBRM2903_350050200
Length:
214

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 1
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 24
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 14
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 12
NetGPI no yes: 0, no: 12
Cellular components
TermNameLevelCount
GO:0005730 nucleolus 5 1
GO:0005737 cytoplasm 2 1
GO:0005840 ribosome 5 1
GO:0015934 large ribosomal subunit 4 12
GO:0022625 cytosolic large ribosomal subunit 5 1
GO:0032991 protein-containing complex 1 12
GO:0043226 organelle 2 2
GO:0043228 non-membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043232 intracellular non-membrane-bounded organelle 4 2
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Expansion

Sequence features

A4HPP4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HPP4

Function

Biological processes
TermNameLevelCount
GO:0000470 maturation of LSU-rRNA 9 1
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006364 rRNA processing 8 1
GO:0006396 RNA processing 6 1
GO:0006412 translation 4 12
GO:0006518 peptide metabolic process 4 12
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009058 biosynthetic process 2 12
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Molecular functions
TermNameLevelCount
GO:0003676 nucleic acid binding 3 12
GO:0003723 RNA binding 4 12
GO:0003735 structural constituent of ribosome 2 12
GO:0005198 structural molecule activity 1 12
GO:0005488 binding 1 12
GO:0097159 organic cyclic compound binding 2 12
GO:1901363 heterocyclic compound binding 2 12
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 22 24 PF00675 0.314
CLV_PCSK_KEX2_1 44 46 PF00082 0.303
CLV_PCSK_PC1ET2_1 44 46 PF00082 0.303
CLV_PCSK_SKI1_1 157 161 PF00082 0.300
CLV_PCSK_SKI1_1 23 27 PF00082 0.303
CLV_PCSK_SKI1_1 95 99 PF00082 0.299
DOC_CDC14_PxL_1 114 122 PF14671 0.289
DOC_CYCLIN_RxL_1 153 164 PF00134 0.297
DOC_MAPK_gen_1 21 31 PF00069 0.307
DOC_MAPK_gen_1 42 52 PF00069 0.303
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IKG0 Leptomonas seymouri 92% 100%
A0A0S4J1H1 Bodo saltans 73% 88%
A0A0S4JHJ4 Bodo saltans 83% 100%
A0A1X0P4H6 Trypanosomatidae 87% 100%
A0A3R7JXU7 Trypanosoma rangeli 89% 100%
A0A3S5H732 Leishmania donovani 94% 100%
A0B922 Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) 31% 100%
A0RX07 Cenarchaeum symbiosum (strain A) 28% 100%
A1AX78 Ruthia magnifica subsp. Calyptogena magnifica 28% 93%
A1RRR1 Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3) 26% 96%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS