LeishMANIAdb
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SKIP_SNW domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
SKIP_SNW domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HPN1_LEIBR
TriTrypDb:
LbrM.35.3870 , LBRM2903_350048800
Length:
121

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HPN1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HPN1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 112 116 PF00082 0.513
CLV_PCSK_SKI1_1 50 54 PF00082 0.561
DOC_WW_Pin1_4 26 31 PF00397 0.498
LIG_14-3-3_CanoR_1 112 117 PF00244 0.591
LIG_BIR_II_1 1 5 PF00653 0.520
LIG_CaM_IQ_9 37 52 PF13499 0.283
LIG_FHA_1 104 110 PF00498 0.428
LIG_LIR_Gen_1 95 104 PF02991 0.521
LIG_LIR_Nem_3 22 26 PF02991 0.376
LIG_LIR_Nem_3 47 52 PF02991 0.533
LIG_LIR_Nem_3 95 99 PF02991 0.529
LIG_PDZ_Class_3 116 121 PF00595 0.565
LIG_Pex14_2 49 53 PF04695 0.527
LIG_SH2_STAP1 42 46 PF00017 0.368
LIG_SUMO_SIM_par_1 24 29 PF11976 0.482
LIG_TRAF2_1 9 12 PF00917 0.370
LIG_UBA3_1 48 56 PF00899 0.465
MOD_CK1_1 31 37 PF00069 0.471
MOD_GSK3_1 3 10 PF00069 0.570
MOD_N-GLC_1 31 36 PF02516 0.474
MOD_NEK2_2 19 24 PF00069 0.273
MOD_PIKK_1 7 13 PF00454 0.346
MOD_Plk_4 44 50 PF00069 0.434
MOD_ProDKin_1 26 32 PF00069 0.505
TRG_ENDOCYTIC_2 96 99 PF00928 0.561
TRG_ER_diArg_1 105 108 PF00400 0.611
TRG_Pf-PMV_PEXEL_1 15 20 PF00026 0.286

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HVF5 Leptomonas seymouri 68% 98%
A0A0S4J3L8 Bodo saltans 38% 86%
A0A1X0P3B7 Trypanosomatidae 54% 100%
A0A3S7XBD5 Leishmania donovani 89% 100%
A0A422MYF0 Trypanosoma rangeli 46% 100%
A4ID35 Leishmania infantum 89% 100%
D0A8I8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 50% 100%
E9ATE3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
Q4Q154 Leishmania major 92% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS