LeishMANIAdb
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ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase a-like protein
Species:
Leishmania braziliensis
UniProt:
A4HPI4_LEIBR
TriTrypDb:
LbrM.35.3400 , LBRM2903_350042800
Length:
1404

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 57
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 45, no: 26
NetGPI no yes: 0, no: 71
Cellular components
Term Name Level Count
GO:0016020 membrane 2 66
GO:0110165 cellular anatomical entity 1 72

Expansion

Sequence features

A4HPI4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 72
GO:0006163 purine nucleotide metabolic process 5 72
GO:0006164 purine nucleotide biosynthetic process 6 72
GO:0006171 cAMP biosynthetic process 8 72
GO:0006725 cellular aromatic compound metabolic process 3 72
GO:0006753 nucleoside phosphate metabolic process 4 72
GO:0006793 phosphorus metabolic process 3 72
GO:0006796 phosphate-containing compound metabolic process 4 72
GO:0006807 nitrogen compound metabolic process 2 72
GO:0007165 signal transduction 2 72
GO:0008152 metabolic process 1 72
GO:0009058 biosynthetic process 2 72
GO:0009117 nucleotide metabolic process 5 72
GO:0009150 purine ribonucleotide metabolic process 6 72
GO:0009152 purine ribonucleotide biosynthetic process 7 72
GO:0009165 nucleotide biosynthetic process 6 72
GO:0009187 cyclic nucleotide metabolic process 6 72
GO:0009190 cyclic nucleotide biosynthetic process 7 72
GO:0009259 ribonucleotide metabolic process 5 72
GO:0009260 ribonucleotide biosynthetic process 6 72
GO:0009987 cellular process 1 72
GO:0018130 heterocycle biosynthetic process 4 72
GO:0019438 aromatic compound biosynthetic process 4 72
GO:0019637 organophosphate metabolic process 3 72
GO:0019693 ribose phosphate metabolic process 4 72
GO:0034641 cellular nitrogen compound metabolic process 3 72
GO:0034654 nucleobase-containing compound biosynthetic process 4 72
GO:0035556 intracellular signal transduction 3 72
GO:0044237 cellular metabolic process 2 72
GO:0044238 primary metabolic process 2 72
GO:0044249 cellular biosynthetic process 3 72
GO:0044271 cellular nitrogen compound biosynthetic process 4 72
GO:0044281 small molecule metabolic process 2 72
GO:0046058 cAMP metabolic process 7 72
GO:0046390 ribose phosphate biosynthetic process 5 72
GO:0046483 heterocycle metabolic process 3 72
GO:0050789 regulation of biological process 2 72
GO:0050794 regulation of cellular process 3 72
GO:0052652 cyclic purine nucleotide metabolic process 6 72
GO:0055086 nucleobase-containing small molecule metabolic process 3 72
GO:0065007 biological regulation 1 72
GO:0071704 organic substance metabolic process 2 72
GO:0072521 purine-containing compound metabolic process 4 72
GO:0072522 purine-containing compound biosynthetic process 5 72
GO:0090407 organophosphate biosynthetic process 4 72
GO:1901135 carbohydrate derivative metabolic process 3 72
GO:1901137 carbohydrate derivative biosynthetic process 4 72
GO:1901293 nucleoside phosphate biosynthetic process 5 72
GO:1901360 organic cyclic compound metabolic process 3 72
GO:1901362 organic cyclic compound biosynthetic process 4 72
GO:1901564 organonitrogen compound metabolic process 3 72
GO:1901566 organonitrogen compound biosynthetic process 4 72
GO:1901576 organic substance biosynthetic process 3 72
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 61
GO:0016829 lyase activity 2 61

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1156 1160 PF00656 0.465
CLV_C14_Caspase3-7 1194 1198 PF00656 0.705
CLV_C14_Caspase3-7 321 325 PF00656 0.387
CLV_C14_Caspase3-7 852 856 PF00656 0.629
CLV_C14_Caspase3-7 913 917 PF00656 0.509
CLV_MEL_PAP_1 428 434 PF00089 0.431
CLV_NRD_NRD_1 1236 1238 PF00675 0.510
CLV_NRD_NRD_1 194 196 PF00675 0.550
CLV_PCSK_KEX2_1 1234 1236 PF00082 0.456
CLV_PCSK_KEX2_1 1325 1327 PF00082 0.414
CLV_PCSK_KEX2_1 194 196 PF00082 0.633
CLV_PCSK_PC1ET2_1 1234 1236 PF00082 0.536
CLV_PCSK_PC1ET2_1 1325 1327 PF00082 0.415
CLV_PCSK_SKI1_1 1049 1053 PF00082 0.334
CLV_PCSK_SKI1_1 1066 1070 PF00082 0.275
CLV_PCSK_SKI1_1 1136 1140 PF00082 0.241
CLV_PCSK_SKI1_1 1152 1156 PF00082 0.384
CLV_PCSK_SKI1_1 1281 1285 PF00082 0.329
CLV_PCSK_SKI1_1 1326 1330 PF00082 0.415
CLV_PCSK_SKI1_1 635 639 PF00082 0.616
CLV_PCSK_SKI1_1 664 668 PF00082 0.574
CLV_PCSK_SKI1_1 725 729 PF00082 0.599
CLV_PCSK_SKI1_1 865 869 PF00082 0.263
DEG_APCC_DBOX_1 724 732 PF00400 0.392
DEG_Nend_Nbox_1 1 3 PF02207 0.558
DEG_ODPH_VHL_1 1091 1103 PF01847 0.523
DEG_SCF_FBW7_1 1294 1301 PF00400 0.401
DEG_SCF_FBW7_1 819 824 PF00400 0.287
DEG_SPOP_SBC_1 116 120 PF00917 0.277
DEG_SPOP_SBC_1 599 603 PF00917 0.454
DOC_ANK_TNKS_1 1207 1214 PF00023 0.514
DOC_CKS1_1 1109 1114 PF01111 0.517
DOC_CYCLIN_RxL_1 1133 1141 PF00134 0.452
DOC_CYCLIN_yCln2_LP_2 1374 1377 PF00134 0.401
DOC_CYCLIN_yCln2_LP_2 515 521 PF00134 0.467
DOC_MAPK_FxFP_2 234 237 PF00069 0.260
DOC_MAPK_gen_1 1234 1241 PF00069 0.742
DOC_MAPK_gen_1 1392 1400 PF00069 0.401
DOC_MAPK_JIP1_4 865 871 PF00069 0.401
DOC_PP1_RVXF_1 662 668 PF00149 0.355
DOC_PP2B_LxvP_1 1373 1376 PF13499 0.618
DOC_PP2B_LxvP_1 259 262 PF13499 0.251
DOC_PP2B_LxvP_1 29 32 PF13499 0.374
DOC_PP4_FxxP_1 234 237 PF00568 0.303
DOC_PP4_FxxP_1 520 523 PF00568 0.308
DOC_USP7_MATH_1 1079 1083 PF00917 0.654
DOC_USP7_MATH_1 116 120 PF00917 0.433
DOC_USP7_MATH_1 238 242 PF00917 0.431
DOC_USP7_MATH_1 319 323 PF00917 0.357
DOC_USP7_MATH_1 377 381 PF00917 0.444
DOC_USP7_MATH_1 464 468 PF00917 0.452
DOC_USP7_MATH_1 477 481 PF00917 0.283
DOC_USP7_MATH_1 572 576 PF00917 0.491
DOC_USP7_MATH_1 599 603 PF00917 0.453
DOC_USP7_MATH_1 658 662 PF00917 0.423
DOC_USP7_MATH_1 720 724 PF00917 0.459
DOC_USP7_MATH_1 952 956 PF00917 0.609
DOC_USP7_MATH_2 1244 1250 PF00917 0.523
DOC_USP7_MATH_2 477 483 PF00917 0.250
DOC_USP7_UBL2_3 1136 1140 PF12436 0.641
DOC_USP7_UBL2_3 861 865 PF12436 0.401
DOC_WW_Pin1_4 1108 1113 PF00397 0.636
DOC_WW_Pin1_4 1124 1129 PF00397 0.489
DOC_WW_Pin1_4 1224 1229 PF00397 0.670
DOC_WW_Pin1_4 1294 1299 PF00397 0.630
DOC_WW_Pin1_4 275 280 PF00397 0.440
DOC_WW_Pin1_4 506 511 PF00397 0.379
DOC_WW_Pin1_4 696 701 PF00397 0.378
DOC_WW_Pin1_4 815 820 PF00397 0.537
DOC_WW_Pin1_4 87 92 PF00397 0.435
DOC_WW_Pin1_4 961 966 PF00397 0.429
DOC_WW_Pin1_4 968 973 PF00397 0.435
LIG_14-3-3_CanoR_1 1049 1054 PF00244 0.473
LIG_14-3-3_CanoR_1 1066 1075 PF00244 0.460
LIG_14-3-3_CanoR_1 1152 1162 PF00244 0.607
LIG_14-3-3_CanoR_1 1172 1180 PF00244 0.628
LIG_14-3-3_CanoR_1 1216 1221 PF00244 0.662
LIG_14-3-3_CanoR_1 1346 1351 PF00244 0.632
LIG_14-3-3_CanoR_1 1394 1400 PF00244 0.564
LIG_14-3-3_CanoR_1 249 256 PF00244 0.427
LIG_14-3-3_CanoR_1 710 715 PF00244 0.378
LIG_Actin_WH2_2 1034 1051 PF00022 0.592
LIG_AP2alpha_1 222 226 PF02296 0.212
LIG_APCC_ABBA_1 637 642 PF00400 0.332
LIG_APCC_ABBA_1 987 992 PF00400 0.598
LIG_BIR_III_2 1209 1213 PF00653 0.695
LIG_BRCT_BRCA1_1 1064 1068 PF00533 0.577
LIG_BRCT_BRCA1_1 1217 1221 PF00533 0.666
LIG_BRCT_BRCA1_1 1305 1309 PF00533 0.609
LIG_BRCT_BRCA1_1 230 234 PF00533 0.371
LIG_BRCT_BRCA1_1 466 470 PF00533 0.396
LIG_BRCT_BRCA1_1 601 605 PF00533 0.436
LIG_BRCT_BRCA1_1 684 688 PF00533 0.309
LIG_CSL_BTD_1 88 91 PF09270 0.350
LIG_eIF4E_1 1369 1375 PF01652 0.564
LIG_FHA_1 1009 1015 PF00498 0.513
LIG_FHA_1 1021 1027 PF00498 0.514
LIG_FHA_1 1050 1056 PF00498 0.598
LIG_FHA_1 1171 1177 PF00498 0.598
LIG_FHA_1 1190 1196 PF00498 0.663
LIG_FHA_1 1236 1242 PF00498 0.613
LIG_FHA_1 1255 1261 PF00498 0.656
LIG_FHA_1 1289 1295 PF00498 0.640
LIG_FHA_1 1378 1384 PF00498 0.615
LIG_FHA_1 150 156 PF00498 0.347
LIG_FHA_1 161 167 PF00498 0.336
LIG_FHA_1 2 8 PF00498 0.513
LIG_FHA_1 20 26 PF00498 0.503
LIG_FHA_1 200 206 PF00498 0.386
LIG_FHA_1 228 234 PF00498 0.325
LIG_FHA_1 427 433 PF00498 0.357
LIG_FHA_1 589 595 PF00498 0.377
LIG_FHA_1 605 611 PF00498 0.348
LIG_FHA_1 612 618 PF00498 0.291
LIG_FHA_1 632 638 PF00498 0.432
LIG_FHA_1 684 690 PF00498 0.427
LIG_FHA_1 731 737 PF00498 0.413
LIG_FHA_1 762 768 PF00498 0.484
LIG_FHA_1 802 808 PF00498 0.383
LIG_FHA_1 818 824 PF00498 0.454
LIG_FHA_1 825 831 PF00498 0.348
LIG_FHA_1 96 102 PF00498 0.431
LIG_FHA_2 1029 1035 PF00498 0.597
LIG_FHA_2 103 109 PF00498 0.348
LIG_FHA_2 1154 1160 PF00498 0.501
LIG_FHA_2 1359 1365 PF00498 0.444
LIG_FHA_2 144 150 PF00498 0.489
LIG_FHA_2 204 210 PF00498 0.397
LIG_FHA_2 453 459 PF00498 0.475
LIG_FHA_2 870 876 PF00498 0.509
LIG_FHA_2 88 94 PF00498 0.363
LIG_FHA_2 911 917 PF00498 0.513
LIG_FHA_2 945 951 PF00498 0.509
LIG_GBD_Chelix_1 931 939 PF00786 0.418
LIG_LIR_Apic_2 1123 1128 PF02991 0.497
LIG_LIR_Apic_2 231 237 PF02991 0.454
LIG_LIR_Apic_2 346 351 PF02991 0.272
LIG_LIR_Apic_2 517 523 PF02991 0.377
LIG_LIR_Gen_1 244 251 PF02991 0.443
LIG_LIR_Gen_1 356 366 PF02991 0.468
LIG_LIR_Gen_1 483 490 PF02991 0.365
LIG_LIR_Gen_1 524 534 PF02991 0.447
LIG_LIR_Gen_1 778 786 PF02991 0.394
LIG_LIR_Gen_1 868 879 PF02991 0.510
LIG_LIR_Gen_1 924 932 PF02991 0.465
LIG_LIR_Nem_3 1037 1043 PF02991 0.608
LIG_LIR_Nem_3 1123 1129 PF02991 0.641
LIG_LIR_Nem_3 1324 1330 PF02991 0.444
LIG_LIR_Nem_3 244 250 PF02991 0.451
LIG_LIR_Nem_3 308 314 PF02991 0.347
LIG_LIR_Nem_3 356 361 PF02991 0.465
LIG_LIR_Nem_3 483 489 PF02991 0.329
LIG_LIR_Nem_3 524 529 PF02991 0.421
LIG_LIR_Nem_3 644 650 PF02991 0.342
LIG_LIR_Nem_3 797 802 PF02991 0.340
LIG_LIR_Nem_3 868 874 PF02991 0.510
LIG_LIR_Nem_3 924 929 PF02991 0.449
LIG_LIR_Nem_3 950 956 PF02991 0.511
LIG_LIR_Nem_3 970 976 PF02991 0.504
LIG_LIR_Nem_3 995 1001 PF02991 0.486
LIG_NRBOX 22 28 PF00104 0.342
LIG_PCNA_yPIPBox_3 249 260 PF02747 0.397
LIG_Pex14_2 222 226 PF04695 0.260
LIG_Pex14_2 358 362 PF04695 0.468
LIG_Pex14_2 846 850 PF04695 0.477
LIG_PTB_Apo_2 138 145 PF02174 0.362
LIG_PTB_Apo_2 356 363 PF02174 0.324
LIG_PTB_Phospho_1 138 144 PF10480 0.278
LIG_Rb_LxCxE_1 916 938 PF01857 0.401
LIG_Rb_pABgroove_1 392 400 PF01858 0.215
LIG_Rb_pABgroove_1 634 642 PF01858 0.334
LIG_SH2_CRK 1001 1005 PF00017 0.597
LIG_SH2_CRK 443 447 PF00017 0.393
LIG_SH2_CRK 526 530 PF00017 0.247
LIG_SH2_CRK 697 701 PF00017 0.464
LIG_SH2_GRB2like 1293 1296 PF00017 0.518
LIG_SH2_GRB2like 357 360 PF00017 0.347
LIG_SH2_GRB2like 526 529 PF00017 0.262
LIG_SH2_NCK_1 208 212 PF00017 0.353
LIG_SH2_PTP2 706 709 PF00017 0.393
LIG_SH2_SRC 1161 1164 PF00017 0.653
LIG_SH2_SRC 1293 1296 PF00017 0.702
LIG_SH2_SRC 526 529 PF00017 0.450
LIG_SH2_STAP1 1395 1399 PF00017 0.436
LIG_SH2_STAP1 174 178 PF00017 0.395
LIG_SH2_STAP1 189 193 PF00017 0.295
LIG_SH2_STAP1 732 736 PF00017 0.428
LIG_SH2_STAP1 779 783 PF00017 0.409
LIG_SH2_STAT3 1129 1132 PF00017 0.414
LIG_SH2_STAT3 732 735 PF00017 0.462
LIG_SH2_STAT5 1125 1128 PF00017 0.597
LIG_SH2_STAT5 1129 1132 PF00017 0.558
LIG_SH2_STAT5 1161 1164 PF00017 0.621
LIG_SH2_STAT5 1293 1296 PF00017 0.668
LIG_SH2_STAT5 1341 1344 PF00017 0.444
LIG_SH2_STAT5 144 147 PF00017 0.396
LIG_SH2_STAT5 160 163 PF00017 0.339
LIG_SH2_STAT5 201 204 PF00017 0.482
LIG_SH2_STAT5 273 276 PF00017 0.387
LIG_SH2_STAT5 345 348 PF00017 0.454
LIG_SH2_STAT5 357 360 PF00017 0.364
LIG_SH2_STAT5 367 370 PF00017 0.307
LIG_SH2_STAT5 440 443 PF00017 0.383
LIG_SH2_STAT5 534 537 PF00017 0.401
LIG_SH2_STAT5 706 709 PF00017 0.317
LIG_SH2_STAT5 732 735 PF00017 0.378
LIG_SH2_STAT5 775 778 PF00017 0.419
LIG_SH2_STAT5 794 797 PF00017 0.281
LIG_SH3_3 1039 1045 PF00018 0.452
LIG_SH3_3 1048 1054 PF00018 0.432
LIG_SH3_3 1222 1228 PF00018 0.694
LIG_SH3_3 276 282 PF00018 0.391
LIG_SH3_3 29 35 PF00018 0.445
LIG_SUMO_SIM_anti_2 1256 1263 PF11976 0.611
LIG_SUMO_SIM_anti_2 20 25 PF11976 0.435
LIG_SUMO_SIM_anti_2 607 614 PF11976 0.360
LIG_SUMO_SIM_anti_2 633 642 PF11976 0.363
LIG_SUMO_SIM_par_1 1165 1171 PF11976 0.476
LIG_SUMO_SIM_par_1 1237 1242 PF11976 0.638
LIG_SUMO_SIM_par_1 1256 1263 PF11976 0.621
LIG_SUMO_SIM_par_1 1266 1271 PF11976 0.672
LIG_SUMO_SIM_par_1 387 393 PF11976 0.432
LIG_SUMO_SIM_par_1 607 614 PF11976 0.410
LIG_SUMO_SIM_par_1 633 642 PF11976 0.421
LIG_TRAF2_1 1031 1034 PF00917 0.538
LIG_TRAF2_1 1249 1252 PF00917 0.690
LIG_TYR_ITIM 441 446 PF00017 0.468
LIG_TYR_ITSM 522 529 PF00017 0.219
LIG_UBA3_1 1315 1322 PF00899 0.444
LIG_UBA3_1 390 396 PF00899 0.436
LIG_UBA3_1 415 419 PF00899 0.234
LIG_WRC_WIRS_1 1080 1085 PF05994 0.468
LIG_WRC_WIRS_1 953 958 PF05994 0.401
LIG_WW_3 1149 1153 PF00397 0.660
MOD_CDK_SPK_2 817 822 PF00069 0.309
MOD_CDK_SPxxK_3 815 822 PF00069 0.383
MOD_CK1_1 104 110 PF00069 0.383
MOD_CK1_1 1127 1133 PF00069 0.519
MOD_CK1_1 118 124 PF00069 0.290
MOD_CK1_1 1250 1256 PF00069 0.711
MOD_CK1_1 176 182 PF00069 0.355
MOD_CK1_1 240 246 PF00069 0.434
MOD_CK1_1 254 260 PF00069 0.324
MOD_CK1_1 37 43 PF00069 0.319
MOD_CK1_1 480 486 PF00069 0.301
MOD_CK1_1 493 499 PF00069 0.375
MOD_CK1_1 566 572 PF00069 0.421
MOD_CK1_1 57 63 PF00069 0.399
MOD_CK1_1 590 596 PF00069 0.426
MOD_CK1_1 682 688 PF00069 0.418
MOD_CK1_1 699 705 PF00069 0.346
MOD_CK1_1 755 761 PF00069 0.413
MOD_CK1_1 87 93 PF00069 0.428
MOD_CK1_1 95 101 PF00069 0.469
MOD_CK1_1 971 977 PF00069 0.565
MOD_CK2_1 1022 1028 PF00069 0.532
MOD_CK2_1 1114 1120 PF00069 0.534
MOD_CK2_1 1220 1226 PF00069 0.560
MOD_CK2_1 1246 1252 PF00069 0.629
MOD_CK2_1 125 131 PF00069 0.446
MOD_CK2_1 1298 1304 PF00069 0.448
MOD_CK2_1 1345 1351 PF00069 0.416
MOD_CK2_1 1358 1364 PF00069 0.458
MOD_CK2_1 452 458 PF00069 0.407
MOD_CK2_1 657 663 PF00069 0.454
MOD_CK2_1 809 815 PF00069 0.508
MOD_CK2_1 869 875 PF00069 0.510
MOD_CK2_1 961 967 PF00069 0.526
MOD_GlcNHglycan 1070 1073 PF01048 0.394
MOD_GlcNHglycan 1173 1176 PF01048 0.372
MOD_GlcNHglycan 1300 1303 PF01048 0.413
MOD_GlcNHglycan 1304 1308 PF01048 0.408
MOD_GlcNHglycan 1395 1398 PF01048 0.425
MOD_GlcNHglycan 163 166 PF01048 0.621
MOD_GlcNHglycan 182 185 PF01048 0.596
MOD_GlcNHglycan 321 324 PF01048 0.615
MOD_GlcNHglycan 36 39 PF01048 0.575
MOD_GlcNHglycan 379 382 PF01048 0.524
MOD_GlcNHglycan 462 465 PF01048 0.610
MOD_GlcNHglycan 466 469 PF01048 0.631
MOD_GlcNHglycan 482 485 PF01048 0.507
MOD_GlcNHglycan 493 496 PF01048 0.507
MOD_GlcNHglycan 552 555 PF01048 0.592
MOD_GlcNHglycan 565 568 PF01048 0.622
MOD_GlcNHglycan 607 610 PF01048 0.561
MOD_GlcNHglycan 660 663 PF01048 0.544
MOD_GlcNHglycan 771 774 PF01048 0.572
MOD_GlcNHglycan 811 814 PF01048 0.773
MOD_GlcNHglycan 93 97 PF01048 0.699
MOD_GlcNHglycan 973 976 PF01048 0.318
MOD_GSK3_1 1004 1011 PF00069 0.536
MOD_GSK3_1 115 122 PF00069 0.361
MOD_GSK3_1 1216 1223 PF00069 0.609
MOD_GSK3_1 1246 1253 PF00069 0.708
MOD_GSK3_1 1268 1275 PF00069 0.736
MOD_GSK3_1 1294 1301 PF00069 0.634
MOD_GSK3_1 13 20 PF00069 0.536
MOD_GSK3_1 133 140 PF00069 0.377
MOD_GSK3_1 1330 1337 PF00069 0.625
MOD_GSK3_1 1358 1365 PF00069 0.630
MOD_GSK3_1 156 163 PF00069 0.463
MOD_GSK3_1 176 183 PF00069 0.271
MOD_GSK3_1 199 206 PF00069 0.416
MOD_GSK3_1 277 284 PF00069 0.437
MOD_GSK3_1 310 317 PF00069 0.431
MOD_GSK3_1 331 338 PF00069 0.328
MOD_GSK3_1 346 353 PF00069 0.323
MOD_GSK3_1 447 454 PF00069 0.412
MOD_GSK3_1 460 467 PF00069 0.411
MOD_GSK3_1 489 496 PF00069 0.353
MOD_GSK3_1 53 60 PF00069 0.331
MOD_GSK3_1 568 575 PF00069 0.418
MOD_GSK3_1 584 591 PF00069 0.379
MOD_GSK3_1 600 607 PF00069 0.397
MOD_GSK3_1 616 623 PF00069 0.362
MOD_GSK3_1 627 634 PF00069 0.383
MOD_GSK3_1 652 659 PF00069 0.436
MOD_GSK3_1 675 682 PF00069 0.360
MOD_GSK3_1 684 691 PF00069 0.403
MOD_GSK3_1 710 717 PF00069 0.448
MOD_GSK3_1 81 88 PF00069 0.414
MOD_GSK3_1 817 824 PF00069 0.472
MOD_GSK3_1 865 872 PF00069 0.522
MOD_GSK3_1 910 917 PF00069 0.516
MOD_GSK3_1 957 964 PF00069 0.628
MOD_GSK3_1 967 974 PF00069 0.601
MOD_LATS_1 11 17 PF00433 0.415
MOD_N-GLC_1 1294 1299 PF02516 0.322
MOD_N-GLC_1 1330 1335 PF02516 0.415
MOD_N-GLC_1 254 259 PF02516 0.467
MOD_N-GLC_1 527 532 PF02516 0.633
MOD_N-GLC_1 808 813 PF02516 0.672
MOD_N-GLC_2 10 12 PF02516 0.544
MOD_N-GLC_2 42 44 PF02516 0.414
MOD_NEK2_1 1 6 PF00069 0.422
MOD_NEK2_1 1068 1073 PF00069 0.587
MOD_NEK2_1 1138 1143 PF00069 0.537
MOD_NEK2_1 1165 1170 PF00069 0.649
MOD_NEK2_1 125 130 PF00069 0.426
MOD_NEK2_1 1254 1259 PF00069 0.589
MOD_NEK2_1 1268 1273 PF00069 0.587
MOD_NEK2_1 1393 1398 PF00069 0.401
MOD_NEK2_1 199 204 PF00069 0.421
MOD_NEK2_1 227 232 PF00069 0.315
MOD_NEK2_1 265 270 PF00069 0.272
MOD_NEK2_1 274 279 PF00069 0.321
MOD_NEK2_1 300 305 PF00069 0.419
MOD_NEK2_1 318 323 PF00069 0.426
MOD_NEK2_1 457 462 PF00069 0.444
MOD_NEK2_1 470 475 PF00069 0.368
MOD_NEK2_1 490 495 PF00069 0.368
MOD_NEK2_1 573 578 PF00069 0.382
MOD_NEK2_1 666 671 PF00069 0.318
MOD_NEK2_1 684 689 PF00069 0.467
MOD_NEK2_1 714 719 PF00069 0.406
MOD_NEK2_1 747 752 PF00069 0.419
MOD_NEK2_1 880 885 PF00069 0.555
MOD_NEK2_2 357 362 PF00069 0.326
MOD_NEK2_2 426 431 PF00069 0.398
MOD_NEK2_2 584 589 PF00069 0.484
MOD_PIKK_1 1 7 PF00454 0.485
MOD_PIKK_1 1247 1253 PF00454 0.731
MOD_PIKK_1 1358 1364 PF00454 0.444
MOD_PIKK_1 249 255 PF00454 0.379
MOD_PIKK_1 268 274 PF00454 0.383
MOD_PIKK_1 350 356 PF00454 0.419
MOD_PIKK_1 452 458 PF00454 0.496
MOD_PIKK_1 641 647 PF00454 0.409
MOD_PIKK_1 730 736 PF00454 0.364
MOD_PK_1 1010 1016 PF00069 0.442
MOD_PK_1 1216 1222 PF00069 0.709
MOD_PKA_1 1235 1241 PF00069 0.735
MOD_PKA_2 1171 1177 PF00069 0.609
MOD_PKA_2 1215 1221 PF00069 0.656
MOD_PKA_2 1235 1241 PF00069 0.744
MOD_PKA_2 1345 1351 PF00069 0.453
MOD_PKA_2 1358 1364 PF00069 0.460
MOD_PKA_2 1393 1399 PF00069 0.401
MOD_PKA_2 193 199 PF00069 0.391
MOD_PKA_2 563 569 PF00069 0.417
MOD_PKA_2 79 85 PF00069 0.413
MOD_Plk_1 1033 1039 PF00069 0.571
MOD_Plk_1 1287 1293 PF00069 0.633
MOD_Plk_1 1334 1340 PF00069 0.618
MOD_Plk_1 426 432 PF00069 0.378
MOD_Plk_1 457 463 PF00069 0.487
MOD_Plk_1 527 533 PF00069 0.339
MOD_Plk_1 57 63 PF00069 0.382
MOD_Plk_1 641 647 PF00069 0.385
MOD_Plk_1 679 685 PF00069 0.449
MOD_Plk_1 740 746 PF00069 0.415
MOD_Plk_2-3 1028 1034 PF00069 0.425
MOD_Plk_2-3 1105 1111 PF00069 0.665
MOD_Plk_2-3 310 316 PF00069 0.441
MOD_Plk_2-3 910 916 PF00069 0.509
MOD_Plk_4 1022 1028 PF00069 0.486
MOD_Plk_4 110 116 PF00069 0.369
MOD_Plk_4 121 127 PF00069 0.357
MOD_Plk_4 1216 1222 PF00069 0.722
MOD_Plk_4 1254 1260 PF00069 0.709
MOD_Plk_4 1288 1294 PF00069 0.687
MOD_Plk_4 156 162 PF00069 0.419
MOD_Plk_4 19 25 PF00069 0.368
MOD_Plk_4 228 234 PF00069 0.405
MOD_Plk_4 260 266 PF00069 0.375
MOD_Plk_4 343 349 PF00069 0.414
MOD_Plk_4 353 359 PF00069 0.270
MOD_Plk_4 521 527 PF00069 0.343
MOD_Plk_4 528 534 PF00069 0.374
MOD_Plk_4 545 551 PF00069 0.389
MOD_Plk_4 684 690 PF00069 0.429
MOD_Plk_4 710 716 PF00069 0.354
MOD_Plk_4 821 827 PF00069 0.353
MOD_Plk_4 865 871 PF00069 0.509
MOD_Plk_4 914 920 PF00069 0.520
MOD_Plk_4 944 950 PF00069 0.436
MOD_ProDKin_1 1108 1114 PF00069 0.632
MOD_ProDKin_1 1124 1130 PF00069 0.488
MOD_ProDKin_1 1224 1230 PF00069 0.670
MOD_ProDKin_1 1294 1300 PF00069 0.630
MOD_ProDKin_1 275 281 PF00069 0.441
MOD_ProDKin_1 506 512 PF00069 0.380
MOD_ProDKin_1 696 702 PF00069 0.377
MOD_ProDKin_1 815 821 PF00069 0.531
MOD_ProDKin_1 87 93 PF00069 0.432
MOD_ProDKin_1 961 967 PF00069 0.429
MOD_ProDKin_1 968 974 PF00069 0.435
MOD_SUMO_rev_2 1242 1249 PF00179 0.532
MOD_SUMO_rev_2 755 761 PF00179 0.282
MOD_SUMO_rev_2 862 867 PF00179 0.401
TRG_DiLeu_BaEn_1 1370 1375 PF01217 0.564
TRG_DiLeu_BaEn_1 153 158 PF01217 0.298
TRG_DiLeu_BaEn_2 662 668 PF01217 0.287
TRG_DiLeu_BaLyEn_6 246 251 PF01217 0.394
TRG_DiLeu_BaLyEn_6 661 666 PF01217 0.304
TRG_ENDOCYTIC_2 1001 1004 PF00928 0.593
TRG_ENDOCYTIC_2 1341 1344 PF00928 0.444
TRG_ENDOCYTIC_2 1395 1398 PF00928 0.438
TRG_ENDOCYTIC_2 189 192 PF00928 0.458
TRG_ENDOCYTIC_2 311 314 PF00928 0.379
TRG_ENDOCYTIC_2 405 408 PF00928 0.361
TRG_ENDOCYTIC_2 443 446 PF00928 0.403
TRG_ENDOCYTIC_2 526 529 PF00928 0.443
TRG_ENDOCYTIC_2 647 650 PF00928 0.344
TRG_ENDOCYTIC_2 706 709 PF00928 0.471
TRG_ENDOCYTIC_2 779 782 PF00928 0.424
TRG_ENDOCYTIC_2 953 956 PF00928 0.515
TRG_ER_diArg_1 1235 1237 PF00400 0.583
TRG_ER_diArg_1 193 195 PF00400 0.434
TRG_ER_diArg_1 976 979 PF00400 0.509
TRG_NLS_MonoCore_2 1233 1238 PF00514 0.527
TRG_Pf-PMV_PEXEL_1 1281 1285 PF00026 0.320
TRG_Pf-PMV_PEXEL_1 249 253 PF00026 0.521
TRG_Pf-PMV_PEXEL_1 725 729 PF00026 0.506
TRG_Pf-PMV_PEXEL_1 933 938 PF00026 0.289

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P457 Leptomonas seymouri 40% 100%
A0A1X0P171 Trypanosomatidae 29% 100%
A0A3Q8IJB0 Leishmania donovani 26% 100%
A0A3S5H6Z8 Leishmania donovani 26% 100%
A0A3S7WU91 Leishmania donovani 27% 99%
A0A3S7WU94 Leishmania donovani 27% 100%
A0A3S7WU95 Leishmania donovani 25% 100%
A0A3S7XB85 Leishmania donovani 70% 100%
A4H8U6 Leishmania braziliensis 27% 100%
A4H8V5 Leishmania braziliensis 29% 100%
A4H8V7 Leishmania braziliensis 30% 100%
A4H8V8 Leishmania braziliensis 27% 100%
A4HX84 Leishmania infantum 27% 100%
A4HX85 Leishmania infantum 26% 100%
A4HX87 Leishmania infantum 27% 100%
A4IDA6 Leishmania infantum 70% 100%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 100%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZWU1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 100%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 100%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 100%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 100%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 100%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
E9AQY0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
E9AQY4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 100%
E9ARD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 100%
E9AT96 Leishmania mexicana (strain MHOM/GT/2001/U1103) 65% 100%
Q25263 Leishmania donovani 26% 100%
Q26721 Trypanosoma brucei brucei 30% 100%
Q27675 Leishmania donovani 27% 100%
Q4Q1A1 Leishmania major 69% 100%
Q4QEH9 Leishmania major 26% 100%
Q4QEI0 Leishmania major 26% 100%
Q4QEI1 Leishmania major 26% 100%
Q4QEI2 Leishmania major 28% 100%
Q4QEI3 Leishmania major 27% 100%
Q99279 Trypanosoma brucei brucei 28% 100%
Q99280 Trypanosoma brucei brucei 30% 100%
V5AYH7 Trypanosoma cruzi 31% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS