37S ribosomal protein S25, mitochondrial

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HPF7_LEIBR

TriTrypDb:

LbrM.35.3130 , LBRM2903_350039800

Length:

347

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HPF7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HPF7

PDB structure(s): 7aih_Al , 7am2_Al , 7ane_Al

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	147	153	PF00089	0.521
CLV_NRD_NRD_1	312	314	PF00675	0.608
CLV_NRD_NRD_1	47	49	PF00675	0.629
CLV_NRD_NRD_1	73	75	PF00675	0.465
CLV_PCSK_KEX2_1	149	151	PF00082	0.400
CLV_PCSK_KEX2_1	59	61	PF00082	0.680
CLV_PCSK_PC1ET2_1	149	151	PF00082	0.442
CLV_PCSK_PC1ET2_1	59	61	PF00082	0.617
CLV_PCSK_PC7_1	55	61	PF00082	0.619
CLV_PCSK_SKI1_1	31	35	PF00082	0.669
CLV_PCSK_SKI1_1	322	326	PF00082	0.531
CLV_PCSK_SKI1_1	8	12	PF00082	0.676
DEG_Nend_UBRbox_3	1	3	PF02207	0.500
DEG_SCF_FBW7_1	18	24	PF00400	0.507
DEG_SPOP_SBC_1	42	46	PF00917	0.572
DOC_CKS1_1	136	141	PF01111	0.474
DOC_CKS1_1	18	23	PF01111	0.697
DOC_CYCLIN_RxL_1	28	37	PF00134	0.668
DOC_MAPK_gen_1	227	235	PF00069	0.582
DOC_USP7_MATH_1	21	25	PF00917	0.578
DOC_USP7_MATH_2	257	263	PF00917	0.481
DOC_USP7_UBL2_3	91	95	PF12436	0.471
DOC_WW_Pin1_4	135	140	PF00397	0.460
DOC_WW_Pin1_4	17	22	PF00397	0.697
DOC_WW_Pin1_4	176	181	PF00397	0.387
DOC_WW_Pin1_4	253	258	PF00397	0.435
DOC_WW_Pin1_4	341	346	PF00397	0.526
LIG_14-3-3_CanoR_1	13	21	PF00244	0.644
LIG_14-3-3_CanoR_1	135	139	PF00244	0.451
LIG_14-3-3_CanoR_1	150	158	PF00244	0.234
LIG_14-3-3_CanoR_1	260	267	PF00244	0.497
LIG_14-3-3_CanoR_1	279	288	PF00244	0.603
LIG_14-3-3_CanoR_1	60	64	PF00244	0.607
LIG_14-3-3_CterR_2	343	347	PF00244	0.754
LIG_APCC_ABBA_1	303	308	PF00400	0.516
LIG_APCC_ABBAyCdc20_2	302	308	PF00400	0.517
LIG_Clathr_ClatBox_1	33	37	PF01394	0.625
LIG_deltaCOP1_diTrp_1	82	90	PF00928	0.484
LIG_FHA_1	123	129	PF00498	0.399
LIG_FHA_1	13	19	PF00498	0.717
LIG_FHA_1	177	183	PF00498	0.414
LIG_FHA_1	188	194	PF00498	0.526
LIG_FHA_1	28	34	PF00498	0.469
LIG_FHA_1	280	286	PF00498	0.474
LIG_FHA_2	254	260	PF00498	0.448
LIG_FHA_2	42	48	PF00498	0.694
LIG_FHA_2	81	87	PF00498	0.523
LIG_HP1_1	110	114	PF01393	0.264
LIG_LIR_Apic_2	152	158	PF02991	0.384
LIG_LIR_Gen_1	178	187	PF02991	0.359
LIG_LIR_Gen_1	82	90	PF02991	0.498
LIG_LIR_Nem_3	106	112	PF02991	0.367
LIG_LIR_Nem_3	127	132	PF02991	0.354
LIG_LIR_Nem_3	178	184	PF02991	0.368
LIG_LIR_Nem_3	287	291	PF02991	0.493
LIG_LIR_Nem_3	82	87	PF02991	0.536
LIG_LIR_Nem_3	88	93	PF02991	0.519
LIG_LRP6_Inhibitor_1	114	120	PF00058	0.533
LIG_Pex14_2	72	76	PF04695	0.453
LIG_SH2_CRK	70	74	PF00017	0.458
LIG_SH2_PTP2	111	114	PF00017	0.261
LIG_SH2_PTP2	245	248	PF00017	0.420
LIG_SH2_SRC	155	158	PF00017	0.470
LIG_SH2_SRC	167	170	PF00017	0.503
LIG_SH2_STAP1	124	128	PF00017	0.394
LIG_SH2_STAT3	131	134	PF00017	0.382
LIG_SH2_STAT3	291	294	PF00017	0.362
LIG_SH2_STAT5	111	114	PF00017	0.386
LIG_SH2_STAT5	124	127	PF00017	0.393
LIG_SH2_STAT5	129	132	PF00017	0.358
LIG_SH2_STAT5	155	158	PF00017	0.470
LIG_SH2_STAT5	167	170	PF00017	0.356
LIG_SH2_STAT5	245	248	PF00017	0.385
LIG_SH3_1	192	198	PF00018	0.453
LIG_SH3_3	104	110	PF00018	0.420
LIG_SH3_3	192	198	PF00018	0.434
LIG_SH3_3	223	229	PF00018	0.446
LIG_SH3_4	95	102	PF00018	0.431
LIG_SUMO_SIM_par_1	111	116	PF11976	0.359
LIG_TRAF2_1	256	259	PF00917	0.523
MOD_CDK_SPxK_1	17	23	PF00069	0.509
MOD_CDK_SPxxK_3	135	142	PF00069	0.358
MOD_CDK_SPxxK_3	253	260	PF00069	0.432
MOD_CK1_1	327	333	PF00069	0.556
MOD_CK2_1	253	259	PF00069	0.452
MOD_CK2_1	80	86	PF00069	0.522
MOD_Cter_Amidation	57	60	PF01082	0.618
MOD_GlcNHglycan	216	219	PF01048	0.512
MOD_GlcNHglycan	317	320	PF01048	0.526
MOD_GlcNHglycan	327	330	PF01048	0.475
MOD_GlcNHglycan	4	7	PF01048	0.729
MOD_GSK3_1	130	137	PF00069	0.511
MOD_GSK3_1	157	164	PF00069	0.353
MOD_GSK3_1	17	24	PF00069	0.693
MOD_GSK3_1	320	327	PF00069	0.565
MOD_N-GLC_1	279	284	PF02516	0.580
MOD_N-GLC_1	315	320	PF02516	0.681
MOD_N-GLC_1	325	330	PF02516	0.651
MOD_N-GLC_1	339	344	PF02516	0.629
MOD_NEK2_1	11	16	PF00069	0.673
MOD_NEK2_1	161	166	PF00069	0.360
MOD_NEK2_1	187	192	PF00069	0.541
MOD_NEK2_1	324	329	PF00069	0.515
MOD_NEK2_1	339	344	PF00069	0.580
MOD_NEK2_2	124	129	PF00069	0.487
MOD_NEK2_2	200	205	PF00069	0.600
MOD_PIKK_1	130	136	PF00454	0.470
MOD_PIKK_1	149	155	PF00454	0.304
MOD_PIKK_1	161	167	PF00454	0.265
MOD_PIKK_1	279	285	PF00454	0.607
MOD_PKA_1	149	155	PF00069	0.522
MOD_PKA_1	48	54	PF00069	0.666
MOD_PKA_1	59	65	PF00069	0.419
MOD_PKA_2	12	18	PF00069	0.744
MOD_PKA_2	134	140	PF00069	0.459
MOD_PKA_2	149	155	PF00069	0.367
MOD_PKA_2	259	265	PF00069	0.489
MOD_PKA_2	59	65	PF00069	0.589
MOD_PKA_2	80	86	PF00069	0.591
MOD_Plk_4	124	130	PF00069	0.385
MOD_Plk_4	320	326	PF00069	0.574
MOD_ProDKin_1	135	141	PF00069	0.453
MOD_ProDKin_1	17	23	PF00069	0.696
MOD_ProDKin_1	176	182	PF00069	0.382
MOD_ProDKin_1	253	259	PF00069	0.436
MOD_ProDKin_1	341	347	PF00069	0.534
MOD_SUMO_rev_2	41	51	PF00179	0.713
TRG_DiLeu_BaEn_1	169	174	PF01217	0.380
TRG_DiLeu_BaLyEn_6	28	33	PF01217	0.696
TRG_ENDOCYTIC_2	111	114	PF00928	0.365
TRG_ENDOCYTIC_2	245	248	PF00928	0.385
TRG_ENDOCYTIC_2	70	73	PF00928	0.456
TRG_ER_diArg_1	278	281	PF00400	0.497
TRG_Pf-PMV_PEXEL_1	239	244	PF00026	0.423

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PED1	Leptomonas seymouri	80%	100%
A0A0S4J0P0	Bodo saltans	58%	100%
A0A1X0NM32	Trypanosomatidae	69%	100%
A0A3R7MQ73	Trypanosoma rangeli	69%	100%
A0A3S7XB37	Leishmania donovani	92%	100%
A4ID79	Leishmania infantum	92%	100%
D0A3H0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	65%	99%
E9AT69	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4Q1C8	Leishmania major	91%	100%
V5BPU3	Trypanosoma cruzi	68%	100%