Serine/arginine repetitive matrix protein 1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HPE3_LEIBR

TriTrypDb:

LbrM.35.2990 , LBRM2903_350038300

Length:

752

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HPE3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HPE3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	171	175	PF00656	0.876
CLV_C14_Caspase3-7	188	192	PF00656	0.594
CLV_C14_Caspase3-7	345	349	PF00656	0.645
CLV_C14_Caspase3-7	621	625	PF00656	0.598
CLV_NRD_NRD_1	119	121	PF00675	0.561
CLV_NRD_NRD_1	135	137	PF00675	0.603
CLV_NRD_NRD_1	166	168	PF00675	0.874
CLV_NRD_NRD_1	179	181	PF00675	0.667
CLV_NRD_NRD_1	20	22	PF00675	0.750
CLV_NRD_NRD_1	210	212	PF00675	0.739
CLV_NRD_NRD_1	249	251	PF00675	0.708
CLV_NRD_NRD_1	294	296	PF00675	0.833
CLV_NRD_NRD_1	316	318	PF00675	0.639
CLV_NRD_NRD_1	429	431	PF00675	0.875
CLV_NRD_NRD_1	479	481	PF00675	0.654
CLV_NRD_NRD_1	489	491	PF00675	0.788
CLV_NRD_NRD_1	503	505	PF00675	0.617
CLV_NRD_NRD_1	513	515	PF00675	0.783
CLV_NRD_NRD_1	554	556	PF00675	0.615
CLV_NRD_NRD_1	706	708	PF00675	0.613
CLV_NRD_NRD_1	90	92	PF00675	0.858
CLV_NRD_NRD_1	99	101	PF00675	0.729
CLV_PCSK_KEX2_1	119	121	PF00082	0.853
CLV_PCSK_KEX2_1	135	137	PF00082	0.603
CLV_PCSK_KEX2_1	166	168	PF00082	0.810
CLV_PCSK_KEX2_1	178	180	PF00082	0.618
CLV_PCSK_KEX2_1	19	21	PF00082	0.758
CLV_PCSK_KEX2_1	210	212	PF00082	0.739
CLV_PCSK_KEX2_1	249	251	PF00082	0.747
CLV_PCSK_KEX2_1	294	296	PF00082	0.794
CLV_PCSK_KEX2_1	316	318	PF00082	0.639
CLV_PCSK_KEX2_1	337	339	PF00082	0.855
CLV_PCSK_KEX2_1	429	431	PF00082	0.875
CLV_PCSK_KEX2_1	481	483	PF00082	0.517
CLV_PCSK_KEX2_1	489	491	PF00082	0.556
CLV_PCSK_KEX2_1	503	505	PF00082	0.661
CLV_PCSK_KEX2_1	513	515	PF00082	0.783
CLV_PCSK_KEX2_1	554	556	PF00082	0.703
CLV_PCSK_KEX2_1	567	569	PF00082	0.823
CLV_PCSK_KEX2_1	706	708	PF00082	0.623
CLV_PCSK_KEX2_1	717	719	PF00082	0.451
CLV_PCSK_KEX2_1	90	92	PF00082	0.858
CLV_PCSK_KEX2_1	98	100	PF00082	0.738
CLV_PCSK_PC1ET2_1	337	339	PF00082	0.816
CLV_PCSK_PC1ET2_1	481	483	PF00082	0.517
CLV_PCSK_PC1ET2_1	567	569	PF00082	0.874
CLV_PCSK_PC1ET2_1	717	719	PF00082	0.380
CLV_PCSK_PC7_1	485	491	PF00082	0.569
CLV_PCSK_SKI1_1	141	145	PF00082	0.614
CLV_PCSK_SKI1_1	714	718	PF00082	0.458
DEG_Kelch_Keap1_1	105	110	PF01344	0.603
DEG_SPOP_SBC_1	14	18	PF00917	0.801
DEG_SPOP_SBC_1	169	173	PF00917	0.878
DEG_SPOP_SBC_1	4	8	PF00917	0.714
DOC_CKS1_1	587	592	PF01111	0.643
DOC_CYCLIN_RxL_1	711	723	PF00134	0.511
DOC_MAPK_FxFP_2	612	615	PF00069	0.512
DOC_PP4_FxxP_1	362	365	PF00568	0.589
DOC_PP4_FxxP_1	612	615	PF00568	0.514
DOC_USP7_MATH_1	121	125	PF00917	0.734
DOC_USP7_MATH_1	15	19	PF00917	0.785
DOC_USP7_MATH_1	165	169	PF00917	0.864
DOC_USP7_MATH_1	209	213	PF00917	0.864
DOC_USP7_MATH_1	241	245	PF00917	0.684
DOC_USP7_MATH_1	321	325	PF00917	0.746
DOC_USP7_MATH_1	377	381	PF00917	0.711
DOC_USP7_MATH_1	4	8	PF00917	0.714
DOC_USP7_MATH_1	425	429	PF00917	0.617
DOC_USP7_MATH_1	484	488	PF00917	0.582
DOC_USP7_MATH_1	52	56	PF00917	0.604
DOC_USP7_MATH_1	543	547	PF00917	0.812
DOC_USP7_MATH_1	681	685	PF00917	0.443
DOC_USP7_UBL2_3	463	467	PF12436	0.748
DOC_USP7_UBL2_3	73	77	PF12436	0.570
DOC_WW_Pin1_4	129	134	PF00397	0.788
DOC_WW_Pin1_4	161	166	PF00397	0.854
DOC_WW_Pin1_4	173	178	PF00397	0.672
DOC_WW_Pin1_4	194	199	PF00397	0.858
DOC_WW_Pin1_4	205	210	PF00397	0.688
DOC_WW_Pin1_4	215	220	PF00397	0.698
DOC_WW_Pin1_4	244	249	PF00397	0.648
DOC_WW_Pin1_4	276	281	PF00397	0.703
DOC_WW_Pin1_4	289	294	PF00397	0.817
DOC_WW_Pin1_4	311	316	PF00397	0.868
DOC_WW_Pin1_4	343	348	PF00397	0.855
DOC_WW_Pin1_4	357	362	PF00397	0.605
DOC_WW_Pin1_4	439	444	PF00397	0.643
DOC_WW_Pin1_4	586	591	PF00397	0.728
LIG_14-3-3_CanoR_1	128	133	PF00244	0.848
LIG_14-3-3_CanoR_1	13	23	PF00244	0.738
LIG_14-3-3_CanoR_1	141	150	PF00244	0.642
LIG_14-3-3_CanoR_1	167	177	PF00244	0.873
LIG_14-3-3_CanoR_1	202	209	PF00244	0.859
LIG_14-3-3_CanoR_1	224	232	PF00244	0.746
LIG_14-3-3_CanoR_1	242	248	PF00244	0.666
LIG_14-3-3_CanoR_1	276	280	PF00244	0.865
LIG_14-3-3_CanoR_1	340	350	PF00244	0.782
LIG_14-3-3_CanoR_1	364	373	PF00244	0.754
LIG_14-3-3_CanoR_1	38	45	PF00244	0.823
LIG_14-3-3_CanoR_1	429	437	PF00244	0.618
LIG_14-3-3_CanoR_1	485	492	PF00244	0.822
LIG_14-3-3_CanoR_1	537	545	PF00244	0.611
LIG_14-3-3_CanoR_1	54	62	PF00244	0.577
LIG_14-3-3_CanoR_1	554	563	PF00244	0.724
LIG_14-3-3_CanoR_1	573	577	PF00244	0.764
LIG_14-3-3_CanoR_1	588	594	PF00244	0.558
LIG_14-3-3_CanoR_1	718	726	PF00244	0.385
LIG_14-3-3_CanoR_1	90	96	PF00244	0.808
LIG_14-3-3_CanoR_1	98	104	PF00244	0.779
LIG_Actin_WH2_2	638	656	PF00022	0.636
LIG_AP_GAE_1	662	668	PF02883	0.640
LIG_BIR_II_1	1	5	PF00653	0.854
LIG_Clathr_ClatBox_1	154	158	PF01394	0.593
LIG_FHA_1	150	156	PF00498	0.801
LIG_FHA_1	629	635	PF00498	0.503
LIG_FHA_1	711	717	PF00498	0.362
LIG_FHA_1	99	105	PF00498	0.620
LIG_FHA_2	169	175	PF00498	0.877
LIG_FHA_2	407	413	PF00498	0.596
LIG_FHA_2	514	520	PF00498	0.819
LIG_LIR_Apic_2	26	31	PF02991	0.823
LIG_LIR_Apic_2	360	365	PF02991	0.735
LIG_LIR_Apic_2	368	374	PF02991	0.810
LIG_LIR_Apic_2	380	385	PF02991	0.634
LIG_LIR_Apic_2	414	420	PF02991	0.617
LIG_LIR_Apic_2	609	615	PF02991	0.524
LIG_LIR_Gen_1	470	479	PF02991	0.504
LIG_LIR_Gen_1	618	623	PF02991	0.599
LIG_LIR_Gen_1	662	670	PF02991	0.643
LIG_LIR_LC3C_4	151	156	PF02991	0.592
LIG_LIR_LC3C_4	745	750	PF02991	0.485
LIG_LIR_Nem_3	470	476	PF02991	0.508
LIG_LIR_Nem_3	613	617	PF02991	0.639
LIG_LIR_Nem_3	618	622	PF02991	0.560
LIG_LIR_Nem_3	662	668	PF02991	0.575
LIG_NRBOX	715	721	PF00104	0.629
LIG_REV1ctd_RIR_1	360	364	PF16727	0.588
LIG_SH2_CRK	28	32	PF00017	0.798
LIG_SH2_CRK	371	375	PF00017	0.730
LIG_SH2_NCK_1	371	375	PF00017	0.730
LIG_SH2_STAT5	382	385	PF00017	0.751
LIG_SH3_1	371	377	PF00018	0.574
LIG_SH3_1	577	583	PF00018	0.595
LIG_SH3_2	219	224	PF14604	0.861
LIG_SH3_3	192	198	PF00018	0.607
LIG_SH3_3	216	222	PF00018	0.865
LIG_SH3_3	370	376	PF00018	0.667
LIG_SH3_3	419	425	PF00018	0.767
LIG_SH3_3	435	441	PF00018	0.658
LIG_SH3_3	521	527	PF00018	0.593
LIG_SH3_3	573	579	PF00018	0.664
LIG_SH3_3	581	587	PF00018	0.762
LIG_SH3_3	746	752	PF00018	0.750
LIG_SUMO_SIM_anti_2	151	160	PF11976	0.591
LIG_SUMO_SIM_anti_2	399	405	PF11976	0.854
LIG_SUMO_SIM_anti_2	646	654	PF11976	0.524
LIG_SUMO_SIM_anti_2	696	701	PF11976	0.653
LIG_SUMO_SIM_par_1	151	160	PF11976	0.833
LIG_SUMO_SIM_par_1	402	409	PF11976	0.848
LIG_SUMO_SIM_par_1	433	442	PF11976	0.791
LIG_WRC_WIRS_1	616	621	PF05994	0.640
LIG_WW_3	95	99	PF00397	0.841
MOD_CDC14_SPxK_1	164	167	PF00782	0.858
MOD_CDC14_SPxK_1	176	179	PF00782	0.669
MOD_CDC14_SPxK_1	208	211	PF00782	0.866
MOD_CDC14_SPxK_1	218	221	PF00782	0.701
MOD_CDC14_SPxK_1	247	250	PF00782	0.611
MOD_CDC14_SPxK_1	314	317	PF00782	0.867
MOD_CDK_SPK_2	161	166	PF00069	0.854
MOD_CDK_SPK_2	173	178	PF00069	0.672
MOD_CDK_SPK_2	194	199	PF00069	0.819
MOD_CDK_SPK_2	205	210	PF00069	0.671
MOD_CDK_SPK_2	244	249	PF00069	0.617
MOD_CDK_SPK_2	276	281	PF00069	0.615
MOD_CDK_SPK_2	289	294	PF00069	0.564
MOD_CDK_SPK_2	311	316	PF00069	0.868
MOD_CDK_SPK_2	439	444	PF00069	0.643
MOD_CDK_SPxK_1	129	135	PF00069	0.789
MOD_CDK_SPxK_1	161	167	PF00069	0.857
MOD_CDK_SPxK_1	173	179	PF00069	0.673
MOD_CDK_SPxK_1	205	211	PF00069	0.872
MOD_CDK_SPxK_1	215	221	PF00069	0.699
MOD_CDK_SPxK_1	244	250	PF00069	0.616
MOD_CDK_SPxK_1	289	295	PF00069	0.867
MOD_CDK_SPxK_1	311	317	PF00069	0.870
MOD_CDK_SPxxK_3	129	136	PF00069	0.788
MOD_CDK_SPxxK_3	173	180	PF00069	0.620
MOD_CDK_SPxxK_3	357	364	PF00069	0.596
MOD_CK1_1	102	108	PF00069	0.853
MOD_CK1_1	168	174	PF00069	0.877
MOD_CK1_1	205	211	PF00069	0.872
MOD_CK1_1	244	250	PF00069	0.708
MOD_CK1_1	254	260	PF00069	0.718
MOD_CK1_1	324	330	PF00069	0.876
MOD_CK1_1	354	360	PF00069	0.609
MOD_CK1_1	37	43	PF00069	0.827
MOD_CK1_1	405	411	PF00069	0.644
MOD_CK1_1	428	434	PF00069	0.641
MOD_CK1_1	509	515	PF00069	0.863
MOD_CK1_1	546	552	PF00069	0.776
MOD_CK1_1	57	63	PF00069	0.566
MOD_CK1_1	572	578	PF00069	0.667
MOD_CK1_1	618	624	PF00069	0.600
MOD_CK1_1	630	636	PF00069	0.369
MOD_CK1_1	66	72	PF00069	0.663
MOD_CK1_1	688	694	PF00069	0.433
MOD_CK2_1	104	110	PF00069	0.606
MOD_CK2_1	225	231	PF00069	0.712
MOD_CK2_1	324	330	PF00069	0.876
MOD_CK2_1	346	352	PF00069	0.861
MOD_CK2_1	396	402	PF00069	0.854
MOD_CK2_1	406	412	PF00069	0.683
MOD_CK2_1	494	500	PF00069	0.623
MOD_CK2_1	513	519	PF00069	0.747
MOD_CK2_1	57	63	PF00069	0.607
MOD_CK2_1	603	609	PF00069	0.816
MOD_CK2_1	732	738	PF00069	0.509
MOD_GlcNHglycan	144	147	PF01048	0.604
MOD_GlcNHglycan	167	170	PF01048	0.877
MOD_GlcNHglycan	205	208	PF01048	0.841
MOD_GlcNHglycan	306	309	PF01048	0.864
MOD_GlcNHglycan	319	322	PF01048	0.650
MOD_GlcNHglycan	396	399	PF01048	0.706
MOD_GlcNHglycan	486	489	PF01048	0.817
MOD_GlcNHglycan	500	503	PF01048	0.632
MOD_GlcNHglycan	56	59	PF01048	0.867
MOD_GlcNHglycan	720	723	PF01048	0.617
MOD_GSK3_1	137	144	PF00069	0.707
MOD_GSK3_1	157	164	PF00069	0.721
MOD_GSK3_1	165	172	PF00069	0.789
MOD_GSK3_1	190	197	PF00069	0.868
MOD_GSK3_1	205	212	PF00069	0.623
MOD_GSK3_1	240	247	PF00069	0.712
MOD_GSK3_1	251	258	PF00069	0.681
MOD_GSK3_1	271	278	PF00069	0.535
MOD_GSK3_1	289	296	PF00069	0.798
MOD_GSK3_1	317	324	PF00069	0.874
MOD_GSK3_1	328	335	PF00069	0.692
MOD_GSK3_1	33	40	PF00069	0.818
MOD_GSK3_1	342	349	PF00069	0.633
MOD_GSK3_1	402	409	PF00069	0.662
MOD_GSK3_1	411	418	PF00069	0.776
MOD_GSK3_1	490	497	PF00069	0.792
MOD_GSK3_1	505	512	PF00069	0.675
MOD_GSK3_1	513	520	PF00069	0.594
MOD_GSK3_1	52	59	PF00069	0.583
MOD_GSK3_1	529	536	PF00069	0.561
MOD_GSK3_1	543	550	PF00069	0.725
MOD_GSK3_1	582	589	PF00069	0.609
MOD_GSK3_1	600	607	PF00069	0.759
MOD_GSK3_1	624	631	PF00069	0.498
MOD_GSK3_1	681	688	PF00069	0.648
MOD_GSK3_1	98	105	PF00069	0.617
MOD_LATS_1	11	17	PF00433	0.592
MOD_LATS_1	134	140	PF00433	0.835
MOD_LATS_1	394	400	PF00433	0.602
MOD_LATS_1	42	48	PF00433	0.607
MOD_LATS_1	515	521	PF00433	0.860
MOD_N-GLC_1	406	411	PF02516	0.593
MOD_N-GLC_1	550	555	PF02516	0.610
MOD_NEK2_1	275	280	PF00069	0.617
MOD_NEK2_1	411	416	PF00069	0.608
MOD_NEK2_1	600	605	PF00069	0.681
MOD_NEK2_1	628	633	PF00069	0.548
MOD_NEK2_1	641	646	PF00069	0.412
MOD_PIKK_1	241	247	PF00454	0.833
MOD_PIKK_1	328	334	PF00454	0.699
MOD_PIKK_1	529	535	PF00454	0.601
MOD_PIKK_1	732	738	PF00454	0.529
MOD_PIKK_1	91	97	PF00454	0.840
MOD_PKA_1	135	141	PF00069	0.777
MOD_PKA_1	513	519	PF00069	0.820
MOD_PKA_1	554	560	PF00069	0.621
MOD_PKA_1	90	96	PF00069	0.847
MOD_PKA_1	98	104	PF00069	0.740
MOD_PKA_2	135	141	PF00069	0.777
MOD_PKA_2	165	171	PF00069	0.869
MOD_PKA_2	184	190	PF00069	0.555
MOD_PKA_2	203	209	PF00069	0.784
MOD_PKA_2	213	219	PF00069	0.686
MOD_PKA_2	241	247	PF00069	0.783
MOD_PKA_2	251	257	PF00069	0.735
MOD_PKA_2	275	281	PF00069	0.842
MOD_PKA_2	293	299	PF00069	0.596
MOD_PKA_2	324	330	PF00069	0.775
MOD_PKA_2	342	348	PF00069	0.568
MOD_PKA_2	363	369	PF00069	0.770
MOD_PKA_2	37	43	PF00069	0.826
MOD_PKA_2	383	389	PF00069	0.538
MOD_PKA_2	4	10	PF00069	0.840
MOD_PKA_2	428	434	PF00069	0.628
MOD_PKA_2	484	490	PF00069	0.773
MOD_PKA_2	505	511	PF00069	0.805
MOD_PKA_2	513	519	PF00069	0.769
MOD_PKA_2	554	560	PF00069	0.776
MOD_PKA_2	572	578	PF00069	0.670
MOD_PKA_2	90	96	PF00069	0.847
MOD_PKA_2	98	104	PF00069	0.740
MOD_PKB_1	504	512	PF00069	0.865
MOD_Plk_1	190	196	PF00069	0.617
MOD_Plk_1	406	412	PF00069	0.595
MOD_Plk_1	688	694	PF00069	0.433
MOD_Plk_2-3	624	630	PF00069	0.634
MOD_Plk_2-3	643	649	PF00069	0.331
MOD_Plk_4	190	196	PF00069	0.617
MOD_Plk_4	262	268	PF00069	0.599
MOD_Plk_4	378	384	PF00069	0.610
MOD_Plk_4	618	624	PF00069	0.333
MOD_Plk_4	688	694	PF00069	0.433
MOD_Plk_4	99	105	PF00069	0.620
MOD_ProDKin_1	129	135	PF00069	0.789
MOD_ProDKin_1	161	167	PF00069	0.857
MOD_ProDKin_1	173	179	PF00069	0.673
MOD_ProDKin_1	194	200	PF00069	0.858
MOD_ProDKin_1	205	211	PF00069	0.691
MOD_ProDKin_1	215	221	PF00069	0.699
MOD_ProDKin_1	244	250	PF00069	0.647
MOD_ProDKin_1	276	282	PF00069	0.703
MOD_ProDKin_1	289	295	PF00069	0.817
MOD_ProDKin_1	311	317	PF00069	0.870
MOD_ProDKin_1	343	349	PF00069	0.854
MOD_ProDKin_1	357	363	PF00069	0.606
MOD_ProDKin_1	439	445	PF00069	0.633
MOD_ProDKin_1	586	592	PF00069	0.727
MOD_SUMO_for_1	287	290	PF00179	0.835
MOD_SUMO_for_1	462	465	PF00179	0.737
MOD_SUMO_for_1	563	566	PF00179	0.618
MOD_SUMO_rev_2	158	163	PF00179	0.596
TRG_DiLeu_BaEn_1	83	88	PF01217	0.576
TRG_DiLeu_BaLyEn_6	715	720	PF01217	0.369
TRG_ENDOCYTIC_2	614	617	PF00928	0.546
TRG_ER_diArg_1	165	167	PF00400	0.859
TRG_ER_diArg_1	177	180	PF00400	0.674
TRG_ER_diArg_1	19	21	PF00400	0.846
TRG_ER_diArg_1	209	211	PF00400	0.706
TRG_ER_diArg_1	248	250	PF00400	0.746
TRG_ER_diArg_1	293	295	PF00400	0.837
TRG_ER_diArg_1	315	317	PF00400	0.614
TRG_ER_diArg_1	503	506	PF00400	0.649
TRG_ER_diArg_1	554	556	PF00400	0.615
TRG_ER_diArg_1	705	707	PF00400	0.628
TRG_ER_diArg_1	89	91	PF00400	0.861
TRG_ER_diArg_1	97	100	PF00400	0.723
TRG_Pf-PMV_PEXEL_1	718	723	PF00026	0.391

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7XB19	Leishmania donovani	67%	100%
A4ICI4	Leishmania infantum	67%	100%
E9AT54	Leishmania mexicana (strain MHOM/GT/2001/U1103)	66%	100%
Q4Q1E3	Leishmania major	65%	99%