Putative caltractin

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Putative caltractin

Gene product:

caltractin, putative

Species:

Leishmania braziliensis

UniProt:

A4HPA9_LEIBR

TriTrypDb:

LbrM.35.2640 , LBRM2903_350033500

Length:

231

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HPA9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HPA9

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	3
GO:0005509	calcium ion binding	5	3
GO:0043167	ion binding	2	3
GO:0043169	cation binding	3	3
GO:0046872	metal ion binding	4	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	67	71	PF00656	0.761
CLV_NRD_NRD_1	148	150	PF00675	0.676
CLV_NRD_NRD_1	182	184	PF00675	0.554
CLV_NRD_NRD_1	225	227	PF00675	0.638
CLV_NRD_NRD_1	5	7	PF00675	0.455
CLV_PCSK_KEX2_1	182	184	PF00082	0.554
CLV_PCSK_KEX2_1	5	7	PF00082	0.517
CLV_PCSK_SKI1_1	149	153	PF00082	0.668
CLV_PCSK_SKI1_1	183	187	PF00082	0.396
CLV_PCSK_SKI1_1	5	9	PF00082	0.513
DEG_APCC_DBOX_1	17	25	PF00400	0.620
DEG_APCC_DBOX_1	4	12	PF00400	0.458
DEG_Nend_UBRbox_3	1	3	PF02207	0.595
DOC_MAPK_gen_1	15	24	PF00069	0.621
DOC_PP1_RVXF_1	21	28	PF00149	0.660
DOC_PP4_FxxP_1	124	127	PF00568	0.773
DOC_WW_Pin1_4	110	115	PF00397	0.710
DOC_WW_Pin1_4	123	128	PF00397	0.646
DOC_WW_Pin1_4	53	58	PF00397	0.710
DOC_WW_Pin1_4	79	84	PF00397	0.618
DOC_WW_Pin1_4	96	101	PF00397	0.784
LIG_14-3-3_CanoR_1	15	25	PF00244	0.590
LIG_14-3-3_CanoR_1	182	192	PF00244	0.468
LIG_FHA_1	161	167	PF00498	0.487
LIG_FHA_1	208	214	PF00498	0.529
LIG_FHA_1	90	96	PF00498	0.776
LIG_FHA_2	15	21	PF00498	0.432
LIG_FHA_2	191	197	PF00498	0.537
LIG_FHA_2	215	221	PF00498	0.506
LIG_FHA_2	65	71	PF00498	0.722
LIG_LIR_Gen_1	141	151	PF02991	0.531
LIG_LIR_Gen_1	163	172	PF02991	0.484
LIG_LIR_Gen_1	216	225	PF02991	0.575
LIG_LIR_Nem_3	141	146	PF02991	0.494
LIG_LIR_Nem_3	163	167	PF02991	0.470
LIG_LIR_Nem_3	169	175	PF02991	0.479
LIG_LIR_Nem_3	199	204	PF02991	0.551
LIG_LIR_Nem_3	216	221	PF02991	0.555
LIG_Rb_pABgroove_1	195	203	PF01858	0.541
LIG_SH2_STAP1	156	160	PF00017	0.479
LIG_SH2_STAP1	162	166	PF00017	0.461
LIG_SH2_STAT5	162	165	PF00017	0.612
LIG_SH2_STAT5	172	175	PF00017	0.403
LIG_SH2_STAT5	9	12	PF00017	0.595
LIG_SH3_3	97	103	PF00018	0.636
LIG_WRC_WIRS_1	215	220	PF05994	0.496
LIG_WRC_WIRS_1	73	78	PF05994	0.757
MOD_CDK_SPK_2	123	128	PF00069	0.654
MOD_CK1_1	126	132	PF00069	0.754
MOD_CK1_1	216	222	PF00069	0.558
MOD_CK1_1	64	70	PF00069	0.796
MOD_CK1_1	89	95	PF00069	0.646
MOD_CK2_1	14	20	PF00069	0.446
MOD_CK2_1	190	196	PF00069	0.554
MOD_CK2_1	66	72	PF00069	0.612
MOD_DYRK1A_RPxSP_1	96	100	PF00069	0.552
MOD_GlcNHglycan	76	79	PF01048	0.649
MOD_GSK3_1	106	113	PF00069	0.790
MOD_GSK3_1	203	210	PF00069	0.580
MOD_GSK3_1	49	56	PF00069	0.671
MOD_GSK3_1	79	86	PF00069	0.592
MOD_NEK2_1	160	165	PF00069	0.469
MOD_NEK2_1	49	54	PF00069	0.555
MOD_NEK2_1	74	79	PF00069	0.721
MOD_PIKK_1	117	123	PF00454	0.780
MOD_PIKK_1	81	87	PF00454	0.553
MOD_PKA_2	14	20	PF00069	0.508
MOD_Plk_1	168	174	PF00069	0.613
MOD_Plk_1	213	219	PF00069	0.482
MOD_Plk_2-3	190	196	PF00069	0.554
MOD_Plk_2-3	214	220	PF00069	0.545
MOD_Plk_4	168	174	PF00069	0.379
MOD_ProDKin_1	110	116	PF00069	0.705
MOD_ProDKin_1	123	129	PF00069	0.639
MOD_ProDKin_1	53	59	PF00069	0.703
MOD_ProDKin_1	79	85	PF00069	0.617
MOD_ProDKin_1	96	102	PF00069	0.787
TRG_DiLeu_BaEn_1	20	25	PF01217	0.619
TRG_ENDOCYTIC_2	172	175	PF00928	0.485
TRG_ER_diArg_1	181	183	PF00400	0.554
TRG_ER_diArg_1	4	6	PF00400	0.453

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5G8	Leptomonas seymouri	52%	100%
A0A3S7XAY6	Leishmania donovani	70%	97%
A0A422NCF5	Trypanosoma rangeli	35%	100%
A4ICE9	Leishmania infantum	70%	97%
E9AT20	Leishmania mexicana (strain MHOM/GT/2001/U1103)	69%	87%
Q4Q1H8	Leishmania major	70%	100%