Putative dipeptidyl-peptidase 8-like serine peptidase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

serine peptidase, Clan SC, Family S9B

Species:

Leishmania braziliensis

UniProt:

A4HPA8_LEIBR

TriTrypDb:

LbrM.35.2630 , LBRM2903_350033400

Length:

851

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HPA8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HPA8

Function

Biological processes
Term	Name	Level	Count
GO:0006508	proteolysis	4	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0019538	protein metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044238	primary metabolic process	2	12
GO:0071704	organic substance metabolic process	2	12
GO:1901564	organonitrogen compound metabolic process	3	12

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	12
GO:0008233	peptidase activity	3	12
GO:0008236	serine-type peptidase activity	4	12
GO:0016787	hydrolase activity	2	12
GO:0017171	serine hydrolase activity	3	12
GO:0140096	catalytic activity, acting on a protein	2	12
GO:0008238	exopeptidase activity	4	1
GO:0008239	dipeptidyl-peptidase activity	5	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	239	243	PF00656	0.394
CLV_C14_Caspase3-7	366	370	PF00656	0.326
CLV_C14_Caspase3-7	752	756	PF00656	0.502
CLV_NRD_NRD_1	582	584	PF00675	0.477
CLV_PCSK_FUR_1	473	477	PF00082	0.610
CLV_PCSK_KEX2_1	475	477	PF00082	0.610
CLV_PCSK_KEX2_1	538	540	PF00082	0.564
CLV_PCSK_KEX2_1	582	584	PF00082	0.478
CLV_PCSK_KEX2_1	661	663	PF00082	0.331
CLV_PCSK_KEX2_1	698	700	PF00082	0.504
CLV_PCSK_PC1ET2_1	475	477	PF00082	0.610
CLV_PCSK_PC1ET2_1	538	540	PF00082	0.636
CLV_PCSK_PC1ET2_1	661	663	PF00082	0.331
CLV_PCSK_PC1ET2_1	698	700	PF00082	0.504
CLV_PCSK_PC7_1	694	700	PF00082	0.504
CLV_PCSK_SKI1_1	443	447	PF00082	0.523
CLV_PCSK_SKI1_1	547	551	PF00082	0.618
CLV_PCSK_SKI1_1	575	579	PF00082	0.371
CLV_PCSK_SKI1_1	74	78	PF00082	0.651
CLV_Separin_Metazoa	81	85	PF03568	0.494
DEG_SCF_FBW7_1	1	8	PF00400	0.420
DEG_SCF_FBW7_2	498	503	PF00400	0.365
DOC_CKS1_1	2	7	PF01111	0.410
DOC_CKS1_1	571	576	PF01111	0.587
DOC_MAPK_gen_1	123	131	PF00069	0.523
DOC_MAPK_gen_1	473	483	PF00069	0.410
DOC_MAPK_gen_1	626	635	PF00069	0.499
DOC_MAPK_JIP1_4	26	32	PF00069	0.446
DOC_MAPK_MEF2A_6	325	334	PF00069	0.391
DOC_MAPK_MEF2A_6	476	485	PF00069	0.410
DOC_MAPK_MEF2A_6	626	635	PF00069	0.407
DOC_MAPK_RevD_3	567	583	PF00069	0.558
DOC_PP1_RVXF_1	232	239	PF00149	0.365
DOC_PP1_RVXF_1	34	40	PF00149	0.470
DOC_PP1_RVXF_1	461	467	PF00149	0.316
DOC_PP1_RVXF_1	722	728	PF00149	0.373
DOC_PP4_FxxP_1	153	156	PF00568	0.436
DOC_PP4_FxxP_1	48	51	PF00568	0.512
DOC_PP4_FxxP_1	592	595	PF00568	0.452
DOC_USP7_MATH_1	156	160	PF00917	0.530
DOC_USP7_MATH_1	19	23	PF00917	0.474
DOC_USP7_MATH_1	343	347	PF00917	0.378
DOC_USP7_MATH_1	5	9	PF00917	0.538
DOC_USP7_MATH_1	684	688	PF00917	0.428
DOC_USP7_MATH_2	823	829	PF00917	0.386
DOC_USP7_UBL2_3	126	130	PF12436	0.543
DOC_USP7_UBL2_3	140	144	PF12436	0.562
DOC_USP7_UBL2_3	371	375	PF12436	0.229
DOC_USP7_UBL2_3	74	78	PF12436	0.672
DOC_WW_Pin1_4	1	6	PF00397	0.530
DOC_WW_Pin1_4	496	501	PF00397	0.299
DOC_WW_Pin1_4	521	526	PF00397	0.337
DOC_WW_Pin1_4	532	537	PF00397	0.349
DOC_WW_Pin1_4	570	575	PF00397	0.580
DOC_WW_Pin1_4	591	596	PF00397	0.443
LIG_14-3-3_CanoR_1	100	108	PF00244	0.419
LIG_14-3-3_CanoR_1	15	23	PF00244	0.364
LIG_14-3-3_CanoR_1	245	250	PF00244	0.332
LIG_14-3-3_CanoR_1	288	292	PF00244	0.382
LIG_14-3-3_CanoR_1	473	479	PF00244	0.390
LIG_14-3-3_CanoR_1	539	545	PF00244	0.496
LIG_14-3-3_CanoR_1	547	552	PF00244	0.567
LIG_14-3-3_CanoR_1	61	70	PF00244	0.721
LIG_14-3-3_CanoR_1	626	632	PF00244	0.438
LIG_14-3-3_CanoR_1	826	830	PF00244	0.383
LIG_14-3-3_CanoR_1	86	94	PF00244	0.551
LIG_Actin_WH2_2	211	227	PF00022	0.229
LIG_Actin_WH2_2	305	323	PF00022	0.376
LIG_Actin_WH2_2	460	477	PF00022	0.391
LIG_BIR_III_4	600	604	PF00653	0.591
LIG_deltaCOP1_diTrp_1	388	395	PF00928	0.329
LIG_EH1_1	804	812	PF00400	0.477
LIG_eIF4E_1	788	794	PF01652	0.414
LIG_FHA_1	107	113	PF00498	0.250
LIG_FHA_1	194	200	PF00498	0.229
LIG_FHA_1	287	293	PF00498	0.329
LIG_FHA_1	314	320	PF00498	0.398
LIG_FHA_1	327	333	PF00498	0.320
LIG_FHA_1	371	377	PF00498	0.353
LIG_FHA_1	557	563	PF00498	0.561
LIG_FHA_1	571	577	PF00498	0.547
LIG_FHA_1	628	634	PF00498	0.251
LIG_FHA_1	674	680	PF00498	0.477
LIG_FHA_1	768	774	PF00498	0.477
LIG_FHA_1	89	95	PF00498	0.619
LIG_FHA_2	181	187	PF00498	0.316
LIG_FHA_2	270	276	PF00498	0.385
LIG_FHA_2	497	503	PF00498	0.401
LIG_FHA_2	747	753	PF00498	0.344
LIG_FHA_2	75	81	PF00498	0.607
LIG_FHA_2	844	850	PF00498	0.461
LIG_GBD_Chelix_1	843	851	PF00786	0.480
LIG_HCF-1_HBM_1	503	506	PF13415	0.329
LIG_HCF-1_HBM_1	513	516	PF13415	0.329
LIG_LIR_Apic_2	46	51	PF02991	0.551
LIG_LIR_Apic_2	477	482	PF02991	0.361
LIG_LIR_Gen_1	158	165	PF02991	0.535
LIG_LIR_Gen_1	17	27	PF02991	0.397
LIG_LIR_Gen_1	232	241	PF02991	0.329
LIG_LIR_Gen_1	328	338	PF02991	0.350
LIG_LIR_Gen_1	340	350	PF02991	0.254
LIG_LIR_Gen_1	669	679	PF02991	0.373
LIG_LIR_Gen_1	814	823	PF02991	0.251
LIG_LIR_LC3C_4	289	293	PF02991	0.308
LIG_LIR_Nem_3	113	118	PF02991	0.495
LIG_LIR_Nem_3	158	163	PF02991	0.482
LIG_LIR_Nem_3	17	23	PF02991	0.404
LIG_LIR_Nem_3	221	226	PF02991	0.305
LIG_LIR_Nem_3	232	238	PF02991	0.316
LIG_LIR_Nem_3	276	282	PF02991	0.316
LIG_LIR_Nem_3	328	334	PF02991	0.310
LIG_LIR_Nem_3	424	430	PF02991	0.324
LIG_LIR_Nem_3	440	445	PF02991	0.256
LIG_LIR_Nem_3	563	569	PF02991	0.597
LIG_LIR_Nem_3	669	675	PF02991	0.373
LIG_LIR_Nem_3	706	710	PF02991	0.347
LIG_LIR_Nem_3	734	738	PF02991	0.358
LIG_LIR_Nem_3	814	820	PF02991	0.336
LIG_LYPXL_yS_3	279	282	PF13949	0.229
LIG_PCNA_yPIPBox_3	211	225	PF02747	0.391
LIG_PDZ_Class_3	846	851	PF00595	0.445
LIG_Pex14_2	723	727	PF04695	0.373
LIG_PTAP_UEV_1	594	599	PF05743	0.606
LIG_PTB_Apo_2	762	769	PF02174	0.251
LIG_PTB_Phospho_1	762	768	PF10480	0.251
LIG_RPA_C_Fungi	240	252	PF08784	0.251
LIG_SH2_CRK	412	416	PF00017	0.470
LIG_SH2_CRK	430	434	PF00017	0.517
LIG_SH2_CRK	479	483	PF00017	0.392
LIG_SH2_CRK	610	614	PF00017	0.406
LIG_SH2_CRK	710	714	PF00017	0.357
LIG_SH2_CRK	817	821	PF00017	0.414
LIG_SH2_GRB2like	118	121	PF00017	0.578
LIG_SH2_NCK_1	16	20	PF00017	0.345
LIG_SH2_NCK_1	294	298	PF00017	0.504
LIG_SH2_NCK_1	430	434	PF00017	0.442
LIG_SH2_PTP2	331	334	PF00017	0.472
LIG_SH2_PTP2	672	675	PF00017	0.442
LIG_SH2_SRC	118	121	PF00017	0.586
LIG_SH2_SRC	240	243	PF00017	0.477
LIG_SH2_SRC	672	675	PF00017	0.477
LIG_SH2_SRC	751	754	PF00017	0.386
LIG_SH2_STAP1	16	20	PF00017	0.345
LIG_SH2_STAP1	270	274	PF00017	0.457
LIG_SH2_STAP1	506	510	PF00017	0.392
LIG_SH2_STAP1	529	533	PF00017	0.432
LIG_SH2_STAP1	710	714	PF00017	0.357
LIG_SH2_STAP1	742	746	PF00017	0.357
LIG_SH2_STAP1	817	821	PF00017	0.477
LIG_SH2_STAT3	217	220	PF00017	0.357
LIG_SH2_STAT3	38	41	PF00017	0.444
LIG_SH2_STAT5	108	111	PF00017	0.455
LIG_SH2_STAT5	115	118	PF00017	0.436
LIG_SH2_STAT5	16	19	PF00017	0.342
LIG_SH2_STAT5	217	220	PF00017	0.357
LIG_SH2_STAT5	226	229	PF00017	0.357
LIG_SH2_STAT5	235	238	PF00017	0.373
LIG_SH2_STAT5	240	243	PF00017	0.373
LIG_SH2_STAT5	318	321	PF00017	0.371
LIG_SH2_STAT5	331	334	PF00017	0.295
LIG_SH2_STAT5	465	468	PF00017	0.457
LIG_SH2_STAT5	508	511	PF00017	0.415
LIG_SH2_STAT5	517	520	PF00017	0.310
LIG_SH2_STAT5	672	675	PF00017	0.357
LIG_SH2_STAT5	678	681	PF00017	0.357
LIG_SH2_STAT5	742	745	PF00017	0.357
LIG_SH2_STAT5	788	791	PF00017	0.442
LIG_SH2_STAT5	9	12	PF00017	0.348
LIG_SH3_3	399	405	PF00018	0.398
LIG_SH3_3	530	536	PF00018	0.580
LIG_SH3_3	539	545	PF00018	0.611
LIG_SH3_3	568	574	PF00018	0.592
LIG_SH3_3	592	598	PF00018	0.485
LIG_SUMO_SIM_anti_2	248	254	PF11976	0.414
LIG_SUMO_SIM_anti_2	640	645	PF11976	0.447
LIG_SUMO_SIM_par_1	193	198	PF11976	0.449
LIG_SUMO_SIM_par_1	289	296	PF11976	0.392
LIG_SUMO_SIM_par_1	29	35	PF11976	0.525
LIG_SUMO_SIM_par_1	480	486	PF11976	0.477
LIG_SUMO_SIM_par_1	575	581	PF11976	0.559
LIG_TRAF2_1	356	359	PF00917	0.504
LIG_TRAF2_1	64	67	PF00917	0.667
LIG_TRAF2_1	77	80	PF00917	0.469
LIG_TRAF2_1	846	849	PF00917	0.575
LIG_TYR_ITSM	327	334	PF00017	0.442
LIG_UBA3_1	131	140	PF00899	0.603
LIG_UBA3_1	348	357	PF00899	0.459
LIG_WRC_WIRS_1	157	162	PF05994	0.599
LIG_WRC_WIRS_1	170	175	PF05994	0.373
LIG_WRC_WIRS_1	664	669	PF05994	0.386
MOD_CDC14_SPxK_1	535	538	PF00782	0.363
MOD_CDK_SPK_2	570	575	PF00069	0.552
MOD_CDK_SPxK_1	521	527	PF00069	0.455
MOD_CDK_SPxK_1	532	538	PF00069	0.489
MOD_CDK_SPxxK_3	532	539	PF00069	0.491
MOD_CK1_1	14	20	PF00069	0.470
MOD_CK1_1	166	172	PF00069	0.416
MOD_CK1_1	269	275	PF00069	0.364
MOD_CK1_1	333	339	PF00069	0.392
MOD_CK1_1	531	537	PF00069	0.511
MOD_CK1_1	596	602	PF00069	0.484
MOD_CK1_1	666	672	PF00069	0.364
MOD_CK1_1	758	764	PF00069	0.425
MOD_CK1_1	771	777	PF00069	0.466
MOD_CK1_1	89	95	PF00069	0.523
MOD_CK2_1	156	162	PF00069	0.600
MOD_CK2_1	180	186	PF00069	0.354
MOD_CK2_1	269	275	PF00069	0.448
MOD_CK2_1	353	359	PF00069	0.410
MOD_CK2_1	74	80	PF00069	0.566
MOD_CK2_1	746	752	PF00069	0.405
MOD_CK2_1	843	849	PF00069	0.454
MOD_GlcNHglycan	109	112	PF01048	0.505
MOD_GlcNHglycan	211	214	PF01048	0.395
MOD_GlcNHglycan	48	51	PF01048	0.551
MOD_GlcNHglycan	587	590	PF01048	0.392
MOD_GlcNHglycan	595	598	PF01048	0.459
MOD_GlcNHglycan	686	689	PF01048	0.425
MOD_GlcNHglycan	757	760	PF01048	0.405
MOD_GSK3_1	1	8	PF00069	0.670
MOD_GSK3_1	14	21	PF00069	0.494
MOD_GSK3_1	236	243	PF00069	0.392
MOD_GSK3_1	251	258	PF00069	0.392
MOD_GSK3_1	282	289	PF00069	0.251
MOD_GSK3_1	326	333	PF00069	0.370
MOD_GSK3_1	477	484	PF00069	0.448
MOD_GSK3_1	517	524	PF00069	0.305
MOD_GSK3_1	528	535	PF00069	0.308
MOD_GSK3_1	543	550	PF00069	0.697
MOD_GSK3_1	556	563	PF00069	0.528
MOD_GSK3_1	767	774	PF00069	0.432
MOD_GSK3_1	811	818	PF00069	0.251
MOD_GSK3_1	84	91	PF00069	0.589
MOD_N-GLC_2	451	453	PF02516	0.504
MOD_N-GLC_2	802	804	PF02516	0.327
MOD_NEK2_1	107	112	PF00069	0.446
MOD_NEK2_1	209	214	PF00069	0.405
MOD_NEK2_1	224	229	PF00069	0.484
MOD_NEK2_1	251	256	PF00069	0.477
MOD_NEK2_1	330	335	PF00069	0.477
MOD_NEK2_1	348	353	PF00069	0.386
MOD_NEK2_1	474	479	PF00069	0.421
MOD_NEK2_1	528	533	PF00069	0.514
MOD_NEK2_1	703	708	PF00069	0.346
MOD_NEK2_1	737	742	PF00069	0.372
MOD_NEK2_1	769	774	PF00069	0.415
MOD_NEK2_1	800	805	PF00069	0.373
MOD_NEK2_2	180	185	PF00069	0.251
MOD_NEK2_2	746	751	PF00069	0.436
MOD_PIKK_1	37	43	PF00454	0.522
MOD_PIKK_1	537	543	PF00454	0.620
MOD_PIKK_1	560	566	PF00454	0.403
MOD_PIKK_1	673	679	PF00454	0.504
MOD_PIKK_1	86	92	PF00454	0.665
MOD_PK_1	245	251	PF00069	0.484
MOD_PK_1	655	661	PF00069	0.392
MOD_PKA_1	74	80	PF00069	0.561
MOD_PKA_2	14	20	PF00069	0.347
MOD_PKA_2	224	230	PF00069	0.357
MOD_PKA_2	287	293	PF00069	0.419
MOD_PKA_2	431	437	PF00069	0.327
MOD_PKA_2	825	831	PF00069	0.403
MOD_PKA_2	99	105	PF00069	0.473
MOD_PKB_1	84	92	PF00069	0.538
MOD_Plk_1	11	17	PF00069	0.590
MOD_Plk_1	166	172	PF00069	0.331
MOD_Plk_1	241	247	PF00069	0.346
MOD_Plk_1	655	661	PF00069	0.349
MOD_Plk_1	673	679	PF00069	0.357
MOD_Plk_2-3	133	139	PF00069	0.585
MOD_Plk_4	166	172	PF00069	0.450
MOD_Plk_4	287	293	PF00069	0.477
MOD_Plk_4	326	332	PF00069	0.357
MOD_Plk_4	5	11	PF00069	0.444
MOD_Plk_4	709	715	PF00069	0.319
MOD_Plk_4	746	752	PF00069	0.436
MOD_Plk_4	815	821	PF00069	0.435
MOD_ProDKin_1	1	7	PF00069	0.523
MOD_ProDKin_1	496	502	PF00069	0.349
MOD_ProDKin_1	521	527	PF00069	0.335
MOD_ProDKin_1	532	538	PF00069	0.355
MOD_ProDKin_1	570	576	PF00069	0.581
MOD_ProDKin_1	591	597	PF00069	0.442
MOD_SUMO_rev_2	133	141	PF00179	0.503
MOD_SUMO_rev_2	366	373	PF00179	0.334
MOD_SUMO_rev_2	67	77	PF00179	0.658
MOD_SUMO_rev_2	692	700	PF00179	0.290
TRG_DiLeu_BaLyEn_6	299	304	PF01217	0.462
TRG_ENDOCYTIC_2	235	238	PF00928	0.375
TRG_ENDOCYTIC_2	279	282	PF00928	0.357
TRG_ENDOCYTIC_2	331	334	PF00928	0.357
TRG_ENDOCYTIC_2	342	345	PF00928	0.357
TRG_ENDOCYTIC_2	412	415	PF00928	0.423
TRG_ENDOCYTIC_2	672	675	PF00928	0.373
TRG_ENDOCYTIC_2	710	713	PF00928	0.357
TRG_ENDOCYTIC_2	817	820	PF00928	0.414
TRG_Pf-PMV_PEXEL_1	302	306	PF00026	0.477
TRG_Pf-PMV_PEXEL_1	845	849	PF00026	0.443

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAL6	Leptomonas seymouri	73%	100%
A0A0S4JPE0	Bodo saltans	39%	100%
A0A1X0NDT3	Trypanosomatidae	47%	98%
A0A3R7RCW5	Trypanosoma rangeli	47%	100%
A0A3S7XAZ8	Leishmania donovani	84%	100%
A1CHP1	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	25%	100%
A1CJQ1	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	24%	93%
A1CX29	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	26%	100%
A1D7R6	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	25%	93%
A2QEK7	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	24%	94%
A4IDL6	Leishmania infantum	84%	100%
A4QYQ5	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	23%	91%
A6SL49	Botryotinia fuckeliana (strain B05.10)	24%	92%
A7EQZ1	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	23%	92%
B0XYK8	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	25%	93%
B0Y6C5	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	26%	100%
B1A4F7	Vespula vulgaris	22%	100%
B2A951	Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)	25%	92%
B2D0J4	Apis mellifera	22%	100%
B2WC36	Pyrenophora tritici-repentis (strain Pt-1C-BFP)	23%	97%
B6HFS8	Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255)	24%	94%
B6QVW4	Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)	24%	95%
B8MTH6	Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)	23%	95%
B8N970	Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167)	27%	100%
C1GT79	Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01)	23%	93%
C7YYG9	Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4)	24%	93%
D0A3B6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	100%
D1Z9B4	Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell)	23%	92%
D4DCG0	Trichophyton verrucosum (strain HKI 0517)	25%	95%
D5GM60	Tuber melanosporum (strain Mel28)	24%	94%
E3QKD2	Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212)	24%	92%
E3S9K3	Pyrenophora teres f. teres (strain 0-1)	23%	94%
E9AT19	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
E9ED72	Metarhizium acridum (strain CQMa 102)	24%	91%
E9ETL5	Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075)	25%	93%
P22411	Sus scrofa	25%	100%
P27487	Homo sapiens	23%	100%
P42658	Homo sapiens	22%	98%
P42659	Bos taurus	22%	99%
P46101	Rattus norvegicus	22%	99%
P81425	Bos taurus	24%	100%
Q0CXB1	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	24%	93%
Q0UVK7	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	22%	93%
Q2HF90	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	23%	92%
Q2UH35	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	27%	100%
Q4Q1H9	Leishmania major	84%	100%
Q4WPH9	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	26%	100%
Q4WX13	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	25%	93%
Q5AZ42	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	27%	100%
Q5B934	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	24%	94%
Q5IS50	Pan troglodytes	21%	100%
Q6F3I7	Pseudoxanthomonas mexicana	24%	100%
Q6V1X1	Homo sapiens	28%	95%
Q7SHU8	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	23%	92%
Q80YA7	Mus musculus	27%	95%
Q86TI2	Homo sapiens	27%	99%
Q8BVG4	Mus musculus	27%	99%
Q96VT7	Aspergillus niger	24%	94%
Q9N2I7	Felis catus	24%	100%
Q9Z218	Mus musculus	22%	100%
V5B849	Trypanosoma cruzi	47%	100%