Putative DEAD box RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA helicase DBP2A, putative

Species:

Leishmania braziliensis

UniProt:

A4HP82_LEIBR

TriTrypDb:

LbrM.35.2370 , LBRM2903_350030300

Length:

571

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 22
NetGPI	no	yes: 0, no: 22

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	3
GO:0005634	nucleus	5	2
GO:0005730	nucleolus	5	2
GO:0032991	protein-containing complex	1	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:1990904	ribonucleoprotein complex	2	2
GO:0005654	nucleoplasm	2	1

Expansion

Sequence features

A4HP82

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HP82

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	23
GO:0003676	nucleic acid binding	3	23
GO:0003824	catalytic activity	1	23
GO:0004386	helicase activity	2	23
GO:0005488	binding	1	23
GO:0005524	ATP binding	5	23
GO:0016787	hydrolase activity	2	23
GO:0017076	purine nucleotide binding	4	23
GO:0030554	adenyl nucleotide binding	5	23
GO:0032553	ribonucleotide binding	3	23
GO:0032555	purine ribonucleotide binding	4	23
GO:0032559	adenyl ribonucleotide binding	5	23
GO:0035639	purine ribonucleoside triphosphate binding	4	23
GO:0036094	small molecule binding	2	23
GO:0043167	ion binding	2	23
GO:0043168	anion binding	3	23
GO:0097159	organic cyclic compound binding	2	23
GO:0097367	carbohydrate derivative binding	2	23
GO:0140640	catalytic activity, acting on a nucleic acid	2	23
GO:0140657	ATP-dependent activity	1	23
GO:1901265	nucleoside phosphate binding	3	23
GO:1901363	heterocyclic compound binding	2	23
GO:0003724	RNA helicase activity	3	13
GO:0003743	translation initiation factor activity	4	10
GO:0008135	translation factor activity, RNA binding	3	10
GO:0008186	ATP-dependent activity, acting on RNA	2	13
GO:0045182	translation regulator activity	1	10
GO:0090079	translation regulator activity, nucleic acid binding	2	10
GO:0140098	catalytic activity, acting on RNA	3	13
GO:0003723	RNA binding	4	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	63	67	PF00656	0.409
CLV_C14_Caspase3-7	91	95	PF00656	0.574
CLV_NRD_NRD_1	23	25	PF00675	0.657
CLV_NRD_NRD_1	393	395	PF00675	0.232
CLV_NRD_NRD_1	58	60	PF00675	0.642
CLV_PCSK_KEX2_1	244	246	PF00082	0.259
CLV_PCSK_KEX2_1	339	341	PF00082	0.256
CLV_PCSK_KEX2_1	368	370	PF00082	0.244
CLV_PCSK_KEX2_1	495	497	PF00082	0.568
CLV_PCSK_KEX2_1	567	569	PF00082	0.702
CLV_PCSK_PC1ET2_1	244	246	PF00082	0.245
CLV_PCSK_PC1ET2_1	339	341	PF00082	0.319
CLV_PCSK_PC1ET2_1	368	370	PF00082	0.244
CLV_PCSK_PC1ET2_1	495	497	PF00082	0.587
CLV_PCSK_PC1ET2_1	567	569	PF00082	0.698
CLV_PCSK_SKI1_1	320	324	PF00082	0.374
DEG_APCC_DBOX_1	244	252	PF00400	0.445
DEG_MDM2_SWIB_1	302	309	PF02201	0.363
DEG_ODPH_VHL_1	531	543	PF01847	0.517
DOC_CKS1_1	231	236	PF01111	0.419
DOC_CYCLIN_yCln2_LP_2	168	174	PF00134	0.525
DOC_MAPK_gen_1	244	251	PF00069	0.525
DOC_MAPK_gen_1	279	287	PF00069	0.425
DOC_MAPK_gen_1	344	353	PF00069	0.435
DOC_MAPK_gen_1	355	365	PF00069	0.445
DOC_MAPK_gen_1	392	401	PF00069	0.425
DOC_MAPK_MEF2A_6	173	182	PF00069	0.445
DOC_MAPK_MEF2A_6	224	231	PF00069	0.419
DOC_MAPK_MEF2A_6	304	311	PF00069	0.329
DOC_PP1_RVXF_1	152	159	PF00149	0.445
DOC_PP1_RVXF_1	234	241	PF00149	0.438
DOC_PP1_RVXF_1	347	354	PF00149	0.419
DOC_PP4_FxxP_1	124	127	PF00568	0.429
DOC_PP4_FxxP_1	158	161	PF00568	0.425
DOC_USP7_MATH_1	30	34	PF00917	0.482
DOC_WW_Pin1_4	125	130	PF00397	0.389
DOC_WW_Pin1_4	230	235	PF00397	0.419
DOC_WW_Pin1_4	4	9	PF00397	0.608
DOC_WW_Pin1_4	535	540	PF00397	0.520
LIG_14-3-3_CanoR_1	250	254	PF00244	0.419
LIG_14-3-3_CanoR_1	282	286	PF00244	0.426
LIG_Actin_WH2_2	159	175	PF00022	0.426
LIG_Actin_WH2_2	234	252	PF00022	0.444
LIG_APCC_ABBA_1	375	380	PF00400	0.419
LIG_BIR_II_1	1	5	PF00653	0.661
LIG_BRCT_BRCA1_1	460	464	PF00533	0.525
LIG_BRCT_BRCA1_1	537	541	PF00533	0.571
LIG_eIF4E_1	114	120	PF01652	0.501
LIG_FHA_1	184	190	PF00498	0.419
LIG_FHA_1	195	201	PF00498	0.419
LIG_FHA_1	250	256	PF00498	0.431
LIG_FHA_1	68	74	PF00498	0.416
LIG_FHA_2	101	107	PF00498	0.353
LIG_FHA_2	450	456	PF00498	0.417
LIG_FHA_2	89	95	PF00498	0.513
LIG_LIR_Apic_2	155	161	PF02991	0.425
LIG_LIR_Gen_1	103	112	PF02991	0.434
LIG_LIR_Gen_1	134	139	PF02991	0.555
LIG_LIR_Gen_1	239	248	PF02991	0.432
LIG_LIR_Gen_1	252	259	PF02991	0.407
LIG_LIR_Gen_1	359	367	PF02991	0.429
LIG_LIR_Gen_1	447	455	PF02991	0.422
LIG_LIR_Gen_1	461	470	PF02991	0.491
LIG_LIR_Nem_3	103	108	PF02991	0.426
LIG_LIR_Nem_3	134	138	PF02991	0.438
LIG_LIR_Nem_3	239	243	PF02991	0.432
LIG_LIR_Nem_3	252	256	PF02991	0.407
LIG_LIR_Nem_3	3	9	PF02991	0.594
LIG_LIR_Nem_3	359	365	PF02991	0.525
LIG_LIR_Nem_3	447	451	PF02991	0.395
LIG_LIR_Nem_3	461	467	PF02991	0.524
LIG_Pex14_2	287	291	PF04695	0.419
LIG_Pex14_2	302	306	PF04695	0.345
LIG_PTB_Apo_2	418	425	PF02174	0.433
LIG_PTB_Apo_2	547	554	PF02174	0.706
LIG_SH2_CRK	422	426	PF00017	0.453
LIG_SH2_CRK	491	495	PF00017	0.674
LIG_SH2_STAT5	114	117	PF00017	0.407
LIG_SH2_STAT5	253	256	PF00017	0.430
LIG_SH2_STAT5	362	365	PF00017	0.525
LIG_SH2_STAT5	431	434	PF00017	0.419
LIG_SH3_3	179	185	PF00018	0.421
LIG_SH3_3	212	218	PF00018	0.425
LIG_SH3_3	228	234	PF00018	0.425
LIG_SUMO_SIM_par_1	465	471	PF11976	0.441
LIG_TRAF2_1	167	170	PF00917	0.445
LIG_TRAF2_1	473	476	PF00917	0.442
LIG_TRAF2_2	425	430	PF00917	0.433
LIG_TRFH_1	529	533	PF08558	0.676
LIG_TYR_ITIM	251	256	PF00017	0.259
LIG_UBA3_1	237	244	PF00899	0.297
LIG_WRC_WIRS_1	501	506	PF05994	0.709
MOD_CDK_SPxK_1	230	236	PF00069	0.261
MOD_CK1_1	152	158	PF00069	0.271
MOD_CK1_1	41	47	PF00069	0.581
MOD_CK1_1	7	13	PF00069	0.622
MOD_CK2_1	449	455	PF00069	0.387
MOD_CK2_1	74	80	PF00069	0.443
MOD_GlcNHglycan	139	142	PF01048	0.311
MOD_GlcNHglycan	151	154	PF01048	0.242
MOD_GlcNHglycan	26	30	PF01048	0.692
MOD_GlcNHglycan	287	290	PF01048	0.276
MOD_GlcNHglycan	40	43	PF01048	0.500
MOD_GlcNHglycan	506	509	PF01048	0.695
MOD_GlcNHglycan	516	520	PF01048	0.654
MOD_GlcNHglycan	522	526	PF01048	0.657
MOD_GlcNHglycan	54	58	PF01048	0.601
MOD_GlcNHglycan	558	564	PF01048	0.668
MOD_GlcNHglycan	9	12	PF01048	0.627
MOD_GSK3_1	133	140	PF00069	0.357
MOD_GSK3_1	281	288	PF00069	0.277
MOD_GSK3_1	449	456	PF00069	0.528
MOD_GSK3_1	500	507	PF00069	0.655
MOD_GSK3_1	67	74	PF00069	0.585
MOD_GSK3_1	7	14	PF00069	0.692
MOD_GSK3_1	86	93	PF00069	0.542
MOD_N-GLC_1	38	43	PF02516	0.492
MOD_N-GLC_1	4	9	PF02516	0.639
MOD_N-GLC_1	458	463	PF02516	0.546
MOD_N-GLC_1	66	71	PF02516	0.429
MOD_NEK2_1	107	112	PF00069	0.432
MOD_NEK2_1	12	17	PF00069	0.727
MOD_NEK2_1	249	254	PF00069	0.269
MOD_NEK2_1	285	290	PF00069	0.283
MOD_NEK2_1	298	303	PF00069	0.345
MOD_NEK2_1	353	358	PF00069	0.270
MOD_NEK2_1	458	463	PF00069	0.569
MOD_NEK2_1	500	505	PF00069	0.680
MOD_PIKK_1	100	106	PF00454	0.472
MOD_PIKK_1	320	326	PF00454	0.350
MOD_PIKK_1	453	459	PF00454	0.491
MOD_PK_1	60	66	PF00069	0.652
MOD_PKA_1	24	30	PF00069	0.656
MOD_PKA_1	394	400	PF00069	0.311
MOD_PKA_2	249	255	PF00069	0.268
MOD_PKA_2	281	287	PF00069	0.261
MOD_PKB_1	392	400	PF00069	0.251
MOD_Plk_1	458	464	PF00069	0.395
MOD_Plk_1	53	59	PF00069	0.655
MOD_Plk_2-3	554	560	PF00069	0.644
MOD_Plk_4	249	255	PF00069	0.277
MOD_Plk_4	281	287	PF00069	0.284
MOD_Plk_4	41	47	PF00069	0.539
MOD_Plk_4	415	421	PF00069	0.300
MOD_Plk_4	459	465	PF00069	0.529
MOD_ProDKin_1	125	131	PF00069	0.301
MOD_ProDKin_1	230	236	PF00069	0.261
MOD_ProDKin_1	4	10	PF00069	0.610
MOD_ProDKin_1	535	541	PF00069	0.521
MOD_SUMO_rev_2	239	246	PF00179	0.317
MOD_SUMO_rev_2	331	341	PF00179	0.336
MOD_SUMO_rev_2	545	553	PF00179	0.510
TRG_DiLeu_BaEn_1	337	342	PF01217	0.317
TRG_DiLeu_BaLyEn_6	233	238	PF01217	0.261
TRG_ENDOCYTIC_2	253	256	PF00928	0.277
TRG_ENDOCYTIC_2	362	365	PF00928	0.275
TRG_ENDOCYTIC_2	6	9	PF00928	0.556
TRG_ER_diArg_1	509	512	PF00400	0.717
TRG_NES_CRM1_1	415	430	PF08389	0.301
TRG_NLS_Bipartite_1	551	571	PF00514	0.618
TRG_NLS_MonoExtN_4	494	499	PF00514	0.560
TRG_NLS_MonoExtN_4	565	571	PF00514	0.624
TRG_Pf-PMV_PEXEL_1	187	191	PF00026	0.261
TRG_Pf-PMV_PEXEL_1	339	343	PF00026	0.308

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6L6	Leptomonas seymouri	33%	100%
A0A0N0P7D9	Leptomonas seymouri	56%	100%
A0A0N0P7N8	Leptomonas seymouri	82%	100%
A0A0N1I5R1	Leptomonas seymouri	23%	72%
A0A0N1I7N1	Leptomonas seymouri	40%	91%
A0A0N1IKV7	Leptomonas seymouri	34%	83%
A0A0N1PDE7	Leptomonas seymouri	31%	99%
A0A0N1PDY8	Leptomonas seymouri	35%	100%
A0A0S4IKX9	Bodo saltans	28%	75%
A0A0S4ITZ4	Bodo saltans	52%	100%
A0A0S4IX79	Bodo saltans	29%	78%
A0A0S4J192	Bodo saltans	42%	95%
A0A0S4JDN6	Bodo saltans	36%	69%
A0A0S4JSZ9	Bodo saltans	29%	94%
A0A0S4JT14	Bodo saltans	59%	100%
A0A0S4KKU4	Bodo saltans	33%	82%
A0A1X0NJH3	Trypanosomatidae	22%	95%
A0A1X0NP86	Trypanosomatidae	55%	100%
A0A1X0NQS6	Trypanosomatidae	32%	100%
A0A1X0NRS9	Trypanosomatidae	38%	73%
A0A1X0NVD0	Trypanosomatidae	29%	99%
A0A1X0P0F9	Trypanosomatidae	33%	100%
A0A1X0P5C7	Trypanosomatidae	39%	72%
A0A1X0P5E1	Trypanosomatidae	31%	80%
A0A1X0P6S6	Trypanosomatidae	40%	87%
A0A1X0P7S4	Trypanosomatidae	33%	92%
A0A1X0P830	Trypanosomatidae	34%	100%
A0A1X0P8K3	Trypanosomatidae	63%	93%
A0A3Q8IC45	Leishmania donovani	31%	100%
A0A3Q8ID91	Leishmania donovani	35%	100%
A0A3Q8IDY0	Leishmania donovani	34%	100%
A0A3Q8IEU7	Leishmania donovani	32%	100%
A0A3Q8IF94	Leishmania donovani	40%	93%
A0A3Q8IQY6	Leishmania donovani	94%	100%
A0A3R7K6G7	Trypanosoma rangeli	54%	100%
A0A3R7KAR1	Trypanosoma rangeli	37%	100%
A0A3R7KKL1	Trypanosoma rangeli	30%	80%
A0A3R7MLR3	Trypanosoma rangeli	25%	94%
A0A3R7N322	Trypanosoma rangeli	41%	95%
A0A3R7RJV1	Trypanosoma rangeli	28%	100%
A0A3S5H4X0	Leishmania donovani	34%	100%
A0A3S5H5G1	Leishmania donovani	33%	84%
A0A3S5H5X3	Leishmania donovani	53%	100%
A0A3S5H7C7	Leishmania donovani	23%	100%
A0A3S7WQ33	Leishmania donovani	34%	83%
A0A3S7WR01	Leishmania donovani	25%	73%
A0A3S7X579	Leishmania donovani	34%	98%
A0A3S7XAT8	Leishmania donovani	33%	100%
A0A422MXD2	Trypanosoma rangeli	39%	72%
A0A422N502	Trypanosoma rangeli	64%	97%
A0A422NDK5	Trypanosoma rangeli	32%	100%
A0A422NKE3	Trypanosoma rangeli	31%	79%
A0A422NLB3	Trypanosoma rangeli	34%	100%
A0A422NYB4	Trypanosoma rangeli	35%	68%
A0A422P419	Trypanosoma rangeli	24%	96%
A1C5V3	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	38%	100%
A1C6C4	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	49%	100%
A1CH78	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	43%	84%
A1CHL3	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	34%	72%
A1CX72	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	34%	72%
A1CXK7	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	41%	84%
A1D405	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	37%	100%
A1D6X9	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	38%	100%
A1DG51	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	37%	100%
A1DGZ7	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	48%	100%
A2QC74	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	48%	100%
A2QFL3	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	39%	100%
A2QI25	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	43%	84%
A2QIL2	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	34%	70%
A3LNL1	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	32%	100%
A3LQ01	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	42%	88%
A3LQW7	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	48%	100%
A3LRW2	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	41%	100%
A4H4Y0	Leishmania braziliensis	49%	100%
A4H5Z5	Leishmania braziliensis	25%	79%
A4HC04	Leishmania braziliensis	30%	100%
A4HGK6	Leishmania braziliensis	34%	100%
A4HGR1	Leishmania braziliensis	35%	100%
A4HK20	Leishmania braziliensis	40%	100%
A4HMX7	Leishmania braziliensis	36%	66%
A4HP49	Leishmania braziliensis	33%	100%
A4HRK0	Leishmania infantum	34%	100%
A4HT33	Leishmania infantum	53%	100%
A4HTF8	Leishmania infantum	34%	83%
A4HUC1	Leishmania infantum	25%	73%
A4I3N2	Leishmania infantum	34%	100%
A4I3T6	Leishmania infantum	35%	100%
A4I7K4	Leishmania infantum	40%	93%
A4I7M5	Leishmania infantum	34%	98%
A4IAT7	Leishmania infantum	32%	100%
A4IDF6	Leishmania infantum	33%	100%
A4IDI7	Leishmania infantum	94%	100%
A4QSS5	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	49%	100%
A4RHF1	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	41%	85%
A4RK80	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	34%	85%
A5A6J2	Pan troglodytes	43%	93%
A5AA68	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	34%	100%
A5D7C1	Bos taurus	33%	96%
A5DAC8	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	41%	100%
A5DDF4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	42%	66%
A5DF03	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	33%	99%
A5DIX5	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	34%	100%
A5DL80	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	47%	100%
A5DQF1	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	34%	100%
A5DQS0	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	42%	90%
A5DS77	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	50%	100%
A5DU73	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	37%	96%
A5DZE6	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	42%	86%
A5E1W4	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	39%	100%
A6QXC1	Ajellomyces capsulatus (strain NAm1 / WU24)	39%	100%
A6R3L3	Ajellomyces capsulatus (strain NAm1 / WU24)	42%	82%
A6RGE3	Ajellomyces capsulatus (strain NAm1 / WU24)	50%	100%
A6RJA2	Botryotinia fuckeliana (strain B05.10)	33%	73%
A6SCT6	Botryotinia fuckeliana (strain B05.10)	37%	96%
A6SEH9	Botryotinia fuckeliana (strain B05.10)	42%	84%
A6SFW7	Botryotinia fuckeliana (strain B05.10)	48%	100%
A6ZLH6	Saccharomyces cerevisiae (strain YJM789)	35%	67%
A6ZP47	Saccharomyces cerevisiae (strain YJM789)	41%	95%
A6ZRX0	Saccharomyces cerevisiae (strain YJM789)	49%	100%
A6ZSX1	Saccharomyces cerevisiae (strain YJM789)	35%	100%
A6ZUA1	Saccharomyces cerevisiae (strain YJM789)	41%	100%
A6ZWD3	Saccharomyces cerevisiae (strain YJM789)	37%	93%
A7E436	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	38%	100%
A7E449	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	48%	100%
A7EGG4	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	33%	70%
A7EJY3	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	43%	84%
A7EYW0	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	38%	96%
A7TJ36	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	40%	100%
A7TKR8	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	43%	88%
A7TS37	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	36%	100%
B0TJ29	Shewanella halifaxensis (strain HAW-EB4)	36%	100%
C4LB49	Tolumonas auensis (strain DSM 9187 / TA4)	34%	100%
C8V8H4	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	43%	85%
C9ZNU6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	89%
C9ZPV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	69%
C9ZUS0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	100%
C9ZYS3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	74%
C9ZZ43	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	77%
D0A0A9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	93%
D0A334	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
D0A378	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	65%	100%
D0A4H6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
D0A6Z3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	21%	95%
D0A872	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
D0A9S3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
D0PV95	Caenorhabditis elegans	40%	81%
E9AEL4	Leishmania major	32%	100%
E9AJG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9AKB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	83%
E9AL45	Leishmania mexicana (strain MHOM/GT/2001/U1103)	60%	100%
E9AM86	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	83%
E9AN20	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	78%
E9ASV7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9ASZ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9AVE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9AZX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9B028	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
E9B2G1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	92%
E9B2I0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	98%
E9B5S5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
G0SFM2	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	50%	100%
O00571	Homo sapiens	41%	86%
O01836	Caenorhabditis elegans	36%	79%
O13370	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	90%
O15523	Homo sapiens	41%	87%
O22907	Arabidopsis thaliana	43%	75%
O62591	Leishmania major	34%	100%
P06634	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	41%	95%
P09052	Drosophila melanogaster	39%	86%
P0CQ74	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	41%	90%
P0CQ75	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	41%	90%
P0CQ76	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	45%	100%
P0CQ77	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	45%	100%
P0CQ78	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	40%	94%
P0CQ79	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	40%	94%
P0CQ88	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	34%	77%
P0CQ89	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	34%	77%
P0CR00	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	35%	100%
P0CR01	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	35%	100%
P16381	Mus musculus	42%	87%
P17844	Homo sapiens	43%	93%
P19109	Drosophila melanogaster	49%	79%
P20447	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	41%	100%
P21372	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	67%
P23394	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	97%
P24346	Xenopus laevis	42%	82%
P24782	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	45%	100%
P24783	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	49%	100%
P24784	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	93%
P34580	Caenorhabditis elegans	35%	100%
P34689	Caenorhabditis elegans	37%	75%
P38712	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	100%
P46942	Nicotiana sylvestris	49%	94%
P93008	Arabidopsis thaliana	38%	78%
Q0CL13	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	40%	100%
Q0CLJ6	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	42%	85%
Q0CLX0	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	32%	73%
Q0DB53	Oryza sativa subsp. japonica	41%	95%
Q0E2Z7	Oryza sativa subsp. japonica	34%	100%
Q0E3X4	Oryza sativa subsp. japonica	42%	91%
Q0UWA6	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	44%	82%
Q0UWC8	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	34%	77%
Q0UY62	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	41%	96%
Q10202	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	99%
Q10MH8	Oryza sativa subsp. japonica	44%	74%
Q1DJF0	Coccidioides immitis (strain RS)	44%	86%
Q1DMX8	Coccidioides immitis (strain RS)	35%	70%
Q1DP69	Coccidioides immitis (strain RS)	47%	100%
Q1DZK8	Coccidioides immitis (strain RS)	41%	100%
Q1E1N5	Coccidioides immitis (strain RS)	37%	100%
Q25225	Leishmania braziliensis	34%	100%
Q26696	Trypanosoma brucei brucei	64%	100%
Q2GUI4	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	44%	100%
Q2H720	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	49%	100%
Q2HBE7	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	41%	83%
Q2HEB0	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	31%	81%
Q2R1M8	Oryza sativa subsp. japonica	43%	92%
Q2U070	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	48%	100%
Q2UGK3	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	43%	85%
Q2UH00	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	34%	71%
Q2UMH8	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	38%	100%
Q3MSQ8	Pelophylax lessonae	39%	79%
Q4I7F9	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	34%	79%
Q4I7K4	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	39%	85%
Q4IF76	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	45%	100%
Q4IJH1	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	40%	98%
Q4JG17	Penaeus vannamei	41%	81%
Q4P3U9	Ustilago maydis (strain 521 / FGSC 9021)	36%	100%
Q4P733	Ustilago maydis (strain 521 / FGSC 9021)	43%	85%
Q4PDT1	Ustilago maydis (strain 521 / FGSC 9021)	43%	98%
Q4PHU9	Ustilago maydis (strain 521 / FGSC 9021)	44%	100%
Q4Q1K8	Leishmania major	92%	100%
Q4Q1N9	Leishmania major	32%	100%
Q4Q5M6	Leishmania major	34%	98%
Q4Q5P5	Leishmania major	39%	93%
Q4Q858	Leishmania major	36%	100%
Q4Q8B2	Leishmania major	34%	100%
Q4QC38	Leishmania major	31%	100%
Q4QHK6	Leishmania major	24%	77%
Q4QIG1	Leishmania major	35%	83%
Q4QIQ9	Leishmania major	51%	100%
Q4QJI9	Leishmania major	33%	85%
Q4R5S7	Macaca fascicularis	41%	79%
Q4R6M5	Macaca fascicularis	43%	93%
Q4WH83	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	40%	100%
Q4WJE9	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	35%	100%
Q4WP13	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	41%	85%
Q4WPE9	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	33%	72%
Q4WXW1	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	36%	100%
Q4X195	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	48%	100%
Q501J6	Mus musculus	49%	88%
Q53RK8	Oryza sativa subsp. japonica	37%	78%
Q54CE0	Dictyostelium discoideum	45%	73%
Q54KG1	Dictyostelium discoideum	41%	85%
Q54QS3	Dictyostelium discoideum	39%	80%
Q54Y81	Dictyostelium discoideum	35%	68%
Q59LU0	Candida albicans (strain SC5314 / ATCC MYA-2876)	48%	100%
Q59W52	Candida albicans (strain SC5314 / ATCC MYA-2876)	35%	98%
Q5A4E2	Candida albicans (strain SC5314 / ATCC MYA-2876)	42%	85%
Q5APT8	Candida albicans (strain SC5314 / ATCC MYA-2876)	41%	100%
Q5AWA6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	37%	100%
Q5B0J9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	47%	100%
Q5B5E7	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	35%	100%
Q5BCU6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	33%	73%
Q5JKF2	Oryza sativa subsp. japonica	48%	72%
Q5N7W4	Oryza sativa subsp. japonica	48%	86%
Q5QMN3	Oryza sativa subsp. japonica	50%	100%
Q5R4I9	Pongo abelii	43%	93%
Q5RC67	Pongo abelii	40%	70%
Q5RF43	Pongo abelii	40%	87%
Q5T1V6	Homo sapiens	37%	92%
Q5VQL1	Oryza sativa subsp. japonica	47%	81%
Q5W5U4	Bos taurus	39%	78%
Q5Z6G5	Oryza sativa subsp. japonica	40%	92%
Q61496	Mus musculus	41%	81%
Q61656	Mus musculus	43%	93%
Q62095	Mus musculus	41%	87%
Q62167	Mus musculus	42%	86%
Q64060	Rattus norvegicus	41%	80%
Q6BLU9	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	36%	98%
Q6BP45	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	31%	100%
Q6BQ61	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	36%	100%
Q6BU54	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	42%	91%
Q6BY27	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	47%	100%
Q6BZ77	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	39%	100%
Q6C024	Yarrowia lipolytica (strain CLIB 122 / E 150)	33%	99%
Q6C4D4	Yarrowia lipolytica (strain CLIB 122 / E 150)	50%	100%
Q6C9P3	Yarrowia lipolytica (strain CLIB 122 / E 150)	41%	100%
Q6CB69	Yarrowia lipolytica (strain CLIB 122 / E 150)	41%	92%
Q6CH58	Yarrowia lipolytica (strain CLIB 122 / E 150)	35%	100%
Q6CIV2	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	47%	100%
Q6CKI1	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	36%	70%
Q6CLR3	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	43%	91%
Q6CT46	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	43%	100%
Q6CT85	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	35%	100%
Q6FLF3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	48%	100%
Q6FM43	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	37%	98%
Q6FML5	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	33%	70%
Q6FNK8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	36%	100%
Q6FP38	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	42%	95%
Q6FS54	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	40%	100%
Q6GVM6	Pan troglodytes	41%	87%
Q6GWX0	Sus scrofa	41%	79%
Q6LLL5	Photobacterium profundum (strain SS9)	34%	100%
Q6YS30	Oryza sativa subsp. japonica	44%	100%
Q6Z4K6	Oryza sativa subsp. japonica	44%	89%
Q754U8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	36%	67%
Q755A5	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	39%	100%
Q755N4	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	48%	100%
Q75B50	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	43%	92%
Q75EW9	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	33%	100%
Q75HJ0	Oryza sativa subsp. japonica	45%	90%
Q7S5R1	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	38%	93%
Q7SBC6	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	47%	100%
Q7SEL0	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	32%	78%
Q84TG1	Arabidopsis thaliana	34%	100%
Q84W89	Arabidopsis thaliana	43%	90%
Q86IZ9	Dictyostelium discoideum	33%	85%
Q86TM3	Homo sapiens	40%	90%
Q887N8	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	38%	100%
Q8H136	Arabidopsis thaliana	47%	92%
Q8K301	Mus musculus	32%	95%
Q8SRB2	Encephalitozoon cuniculi (strain GB-M1)	42%	100%
Q8TFK8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	40%	93%
Q8W4R3	Arabidopsis thaliana	48%	97%
Q91372	Xenopus laevis	37%	82%
Q91VN6	Mus musculus	40%	92%
Q92841	Homo sapiens	49%	78%
Q99PT0	Rattus norvegicus	33%	95%
Q9BUQ8	Homo sapiens	40%	70%
Q9C551	Arabidopsis thaliana	46%	100%
Q9C718	Arabidopsis thaliana	49%	100%
Q9DBN9	Mus musculus	37%	92%
Q9LU46	Arabidopsis thaliana	39%	97%
Q9LUW5	Arabidopsis thaliana	37%	93%
Q9LYJ9	Arabidopsis thaliana	47%	89%
Q9M2F9	Arabidopsis thaliana	42%	88%
Q9NQI0	Homo sapiens	41%	79%
Q9NXZ2	Homo sapiens	40%	88%
Q9P6N8	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	100%
Q9P6U9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	42%	83%
Q9SZB4	Arabidopsis thaliana	40%	100%
Q9UJV9	Homo sapiens	40%	92%
Q9V3C0	Drosophila melanogaster	39%	92%
Q9VHP0	Drosophila melanogaster	39%	72%
Q9Y2R4	Homo sapiens	32%	95%
Q9Y7T7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	86%
V5AST3	Trypanosoma cruzi	54%	100%
V5B4A8	Trypanosoma cruzi	33%	100%
V5BAS2	Trypanosoma cruzi	29%	100%
V5BEY7	Trypanosoma cruzi	32%	93%
V5BGF4	Trypanosoma cruzi	71%	100%
V5BL56	Trypanosoma cruzi	37%	100%
V5BS80	Trypanosoma cruzi	41%	90%
V5CZW7	Trypanosoma cruzi	33%	100%
V5DUK0	Trypanosoma cruzi	31%	75%