Putative mismatch repair protein MSH8

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA mismatch repair protein MSH6, putative

Species:

Leishmania braziliensis

UniProt:

A4HP61_LEIBR

TriTrypDb:

LbrM.35.2160 , LBRM2903_350027900

Length:

1014

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005739	mitochondrion	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HP61

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HP61

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	11
GO:0006259	DNA metabolic process	4	11
GO:0006281	DNA repair	5	11
GO:0006298	mismatch repair	6	11
GO:0006725	cellular aromatic compound metabolic process	3	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0006950	response to stress	2	11
GO:0006974	DNA damage response	4	11
GO:0008152	metabolic process	1	11
GO:0009987	cellular process	1	11
GO:0033554	cellular response to stress	3	11
GO:0034641	cellular nitrogen compound metabolic process	3	11
GO:0043170	macromolecule metabolic process	3	11
GO:0044237	cellular metabolic process	2	11
GO:0044238	primary metabolic process	2	11
GO:0044260	obsolete cellular macromolecule metabolic process	3	11
GO:0046483	heterocycle metabolic process	3	11
GO:0050896	response to stimulus	1	11
GO:0051716	cellular response to stimulus	2	11
GO:0071704	organic substance metabolic process	2	11
GO:0090304	nucleic acid metabolic process	4	11
GO:1901360	organic cyclic compound metabolic process	3	11
GO:0032042	mitochondrial DNA metabolic process	5	1
GO:0043504	mitochondrial DNA repair	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003676	nucleic acid binding	3	11
GO:0003677	DNA binding	4	11
GO:0003690	double-stranded DNA binding	5	11
GO:0003824	catalytic activity	1	11
GO:0005488	binding	1	11
GO:0005524	ATP binding	5	11
GO:0008094	ATP-dependent activity, acting on DNA	2	11
GO:0017076	purine nucleotide binding	4	11
GO:0030554	adenyl nucleotide binding	5	11
GO:0030983	mismatched DNA binding	6	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032559	adenyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:0140097	catalytic activity, acting on DNA	3	11
GO:0140299	small molecule sensor activity	1	11
GO:0140612	DNA damage sensor activity	2	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	11
GO:0140657	ATP-dependent activity	1	11
GO:0140664	ATP-dependent DNA damage sensor activity	3	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	209	213	PF00656	0.538
CLV_NRD_NRD_1	192	194	PF00675	0.341
CLV_NRD_NRD_1	357	359	PF00675	0.499
CLV_NRD_NRD_1	367	369	PF00675	0.379
CLV_NRD_NRD_1	411	413	PF00675	0.311
CLV_NRD_NRD_1	608	610	PF00675	0.314
CLV_NRD_NRD_1	903	905	PF00675	0.160
CLV_PCSK_KEX2_1	192	194	PF00082	0.349
CLV_PCSK_KEX2_1	221	223	PF00082	0.583
CLV_PCSK_KEX2_1	367	369	PF00082	0.392
CLV_PCSK_KEX2_1	411	413	PF00082	0.217
CLV_PCSK_KEX2_1	459	461	PF00082	0.217
CLV_PCSK_KEX2_1	563	565	PF00082	0.304
CLV_PCSK_KEX2_1	608	610	PF00082	0.314
CLV_PCSK_KEX2_1	903	905	PF00082	0.160
CLV_PCSK_PC1ET2_1	221	223	PF00082	0.583
CLV_PCSK_PC1ET2_1	459	461	PF00082	0.217
CLV_PCSK_PC1ET2_1	563	565	PF00082	0.268
CLV_PCSK_SKI1_1	165	169	PF00082	0.432
CLV_PCSK_SKI1_1	292	296	PF00082	0.605
CLV_PCSK_SKI1_1	411	415	PF00082	0.280
CLV_PCSK_SKI1_1	527	531	PF00082	0.321
CLV_PCSK_SKI1_1	628	632	PF00082	0.294
CLV_PCSK_SKI1_1	653	657	PF00082	0.248
CLV_PCSK_SKI1_1	673	677	PF00082	0.260
CLV_PCSK_SKI1_1	771	775	PF00082	0.410
CLV_PCSK_SKI1_1	815	819	PF00082	0.221
CLV_PCSK_SKI1_1	86	90	PF00082	0.273
CLV_PCSK_SKI1_1	903	907	PF00082	0.268
DEG_ODPH_VHL_1	172	183	PF01847	0.412
DEG_SPOP_SBC_1	558	562	PF00917	0.426
DEG_SPOP_SBC_1	584	588	PF00917	0.511
DOC_CKS1_1	149	154	PF01111	0.417
DOC_CYCLIN_yClb5_NLxxxL_5	438	447	PF00134	0.468
DOC_CYCLIN_yClb5_NLxxxL_5	506	513	PF00134	0.511
DOC_CYCLIN_yCln2_LP_2	799	805	PF00134	0.468
DOC_MAPK_DCC_7	744	754	PF00069	0.224
DOC_MAPK_FxFP_2	15	18	PF00069	0.435
DOC_MAPK_gen_1	358	365	PF00069	0.392
DOC_MAPK_gen_1	367	375	PF00069	0.330
DOC_MAPK_gen_1	459	469	PF00069	0.468
DOC_MAPK_gen_1	506	513	PF00069	0.445
DOC_MAPK_gen_1	53	62	PF00069	0.430
DOC_MAPK_MEF2A_6	236	245	PF00069	0.357
DOC_MAPK_MEF2A_6	506	513	PF00069	0.498
DOC_MAPK_MEF2A_6	55	63	PF00069	0.448
DOC_MAPK_MEF2A_6	628	637	PF00069	0.432
DOC_MAPK_MEF2A_6	788	796	PF00069	0.445
DOC_MAPK_MEF2A_6	828	837	PF00069	0.417
DOC_MAPK_MEF2A_6	968	976	PF00069	0.430
DOC_PP2B_LxvP_1	297	300	PF13499	0.393
DOC_PP2B_LxvP_1	579	582	PF13499	0.468
DOC_PP4_FxxP_1	15	18	PF00568	0.435
DOC_USP7_MATH_1	103	107	PF00917	0.430
DOC_USP7_MATH_1	267	271	PF00917	0.349
DOC_USP7_MATH_1	421	425	PF00917	0.473
DOC_USP7_MATH_1	558	562	PF00917	0.423
DOC_USP7_MATH_1	574	578	PF00917	0.429
DOC_USP7_MATH_1	584	588	PF00917	0.419
DOC_USP7_MATH_1	781	785	PF00917	0.417
DOC_USP7_MATH_1	942	946	PF00917	0.544
DOC_USP7_MATH_1	947	951	PF00917	0.423
DOC_USP7_MATH_2	285	291	PF00917	0.280
DOC_WW_Pin1_4	148	153	PF00397	0.442
DOC_WW_Pin1_4	580	585	PF00397	0.496
DOC_WW_Pin1_4	641	646	PF00397	0.511
DOC_WW_Pin1_4	808	813	PF00397	0.511
DOC_WW_Pin1_4	905	910	PF00397	0.462
LIG_14-3-3_CanoR_1	205	214	PF00244	0.414
LIG_14-3-3_CanoR_1	236	245	PF00244	0.445
LIG_14-3-3_CanoR_1	358	365	PF00244	0.347
LIG_14-3-3_CanoR_1	412	418	PF00244	0.422
LIG_14-3-3_CanoR_1	420	428	PF00244	0.410
LIG_14-3-3_CanoR_1	484	490	PF00244	0.508
LIG_14-3-3_CanoR_1	571	579	PF00244	0.360
LIG_14-3-3_CanoR_1	653	659	PF00244	0.420
LIG_14-3-3_CanoR_1	706	711	PF00244	0.509
LIG_14-3-3_CanoR_1	860	870	PF00244	0.417
LIG_BIR_II_1	1	5	PF00653	0.526
LIG_BRCT_BRCA1_1	11	15	PF00533	0.461
LIG_BRCT_BRCA1_1	214	218	PF00533	0.418
LIG_BRCT_BRCA1_1	474	478	PF00533	0.464
LIG_BRCT_BRCA1_1	586	590	PF00533	0.418
LIG_BRCT_BRCA1_1	953	957	PF00533	0.458
LIG_Clathr_ClatBox_1	630	634	PF01394	0.473
LIG_CtBP_PxDLS_1	777	783	PF00389	0.417
LIG_deltaCOP1_diTrp_1	109	116	PF00928	0.417
LIG_Dynein_DLC8_1	902	908	PF01221	0.360
LIG_FHA_1	29	35	PF00498	0.443
LIG_FHA_1	317	323	PF00498	0.303
LIG_FHA_1	330	336	PF00498	0.343
LIG_FHA_1	560	566	PF00498	0.390
LIG_FHA_1	584	590	PF00498	0.494
LIG_FHA_1	592	598	PF00498	0.439
LIG_FHA_1	703	709	PF00498	0.415
LIG_FHA_1	787	793	PF00498	0.417
LIG_FHA_1	830	836	PF00498	0.435
LIG_FHA_1	838	844	PF00498	0.460
LIG_FHA_2	152	158	PF00498	0.417
LIG_FHA_2	207	213	PF00498	0.602
LIG_FHA_2	269	275	PF00498	0.423
LIG_FHA_2	277	283	PF00498	0.478
LIG_FHA_2	302	308	PF00498	0.250
LIG_FHA_2	554	560	PF00498	0.468
LIG_FHA_2	665	671	PF00498	0.515
LIG_FHA_2	732	738	PF00498	0.477
LIG_FHA_2	804	810	PF00498	0.511
LIG_FHA_2	906	912	PF00498	0.360
LIG_LIR_Apic_2	12	18	PF02991	0.446
LIG_LIR_Apic_2	657	663	PF02991	0.360
LIG_LIR_Gen_1	1009	1014	PF02991	0.496
LIG_LIR_Gen_1	109	116	PF02991	0.419
LIG_LIR_Gen_1	311	318	PF02991	0.377
LIG_LIR_Gen_1	468	478	PF02991	0.437
LIG_LIR_Gen_1	54	63	PF02991	0.448
LIG_LIR_Gen_1	621	631	PF02991	0.391
LIG_LIR_Gen_1	73	79	PF02991	0.448
LIG_LIR_Gen_1	814	825	PF02991	0.425
LIG_LIR_Gen_1	831	842	PF02991	0.417
LIG_LIR_Gen_1	891	902	PF02991	0.417
LIG_LIR_Nem_3	1009	1014	PF02991	0.496
LIG_LIR_Nem_3	109	113	PF02991	0.419
LIG_LIR_Nem_3	14	20	PF02991	0.359
LIG_LIR_Nem_3	263	268	PF02991	0.404
LIG_LIR_Nem_3	311	316	PF02991	0.413
LIG_LIR_Nem_3	46	52	PF02991	0.417
LIG_LIR_Nem_3	468	473	PF02991	0.424
LIG_LIR_Nem_3	475	481	PF02991	0.428
LIG_LIR_Nem_3	54	60	PF02991	0.417
LIG_LIR_Nem_3	621	626	PF02991	0.391
LIG_LIR_Nem_3	696	701	PF02991	0.476
LIG_LIR_Nem_3	726	732	PF02991	0.386
LIG_LIR_Nem_3	73	77	PF02991	0.448
LIG_LIR_Nem_3	809	813	PF02991	0.433
LIG_LIR_Nem_3	814	820	PF02991	0.426
LIG_LIR_Nem_3	831	837	PF02991	0.417
LIG_LIR_Nem_3	891	897	PF02991	0.417
LIG_LYPXL_yS_3	17	20	PF13949	0.465
LIG_LYPXL_yS_3	729	732	PF13949	0.386
LIG_NRBOX	237	243	PF00104	0.387
LIG_NRBOX	547	553	PF00104	0.511
LIG_NRBOX	710	716	PF00104	0.360
LIG_PDZ_Class_2	1009	1014	PF00595	0.519
LIG_Pex14_1	110	114	PF04695	0.417
LIG_Pex14_1	525	529	PF04695	0.511
LIG_Pex14_2	15	19	PF04695	0.443
LIG_Pex14_2	365	369	PF04695	0.291
LIG_Pex14_2	698	702	PF04695	0.527
LIG_PTAP_UEV_1	24	29	PF05743	0.521
LIG_PTB_Apo_2	201	208	PF02174	0.380
LIG_PTB_Apo_2	77	84	PF02174	0.500
LIG_Rb_pABgroove_1	563	571	PF01858	0.473
LIG_REV1ctd_RIR_1	60	69	PF16727	0.430
LIG_SH2_CRK	441	445	PF00017	0.468
LIG_SH2_CRK	57	61	PF00017	0.469
LIG_SH2_CRK	74	78	PF00017	0.388
LIG_SH2_CRK	872	876	PF00017	0.488
LIG_SH2_CRK	894	898	PF00017	0.417
LIG_SH2_CRK	959	963	PF00017	0.430
LIG_SH2_PTP2	498	501	PF00017	0.511
LIG_SH2_PTP2	660	663	PF00017	0.360
LIG_SH2_PTP2	834	837	PF00017	0.430
LIG_SH2_SRC	38	41	PF00017	0.432
LIG_SH2_SRC	498	501	PF00017	0.511
LIG_SH2_STAP1	331	335	PF00017	0.380
LIG_SH2_STAP1	72	76	PF00017	0.428
LIG_SH2_STAT5	312	315	PF00017	0.340
LIG_SH2_STAT5	331	334	PF00017	0.379
LIG_SH2_STAT5	38	41	PF00017	0.560
LIG_SH2_STAT5	498	501	PF00017	0.524
LIG_SH2_STAT5	660	663	PF00017	0.448
LIG_SH2_STAT5	710	713	PF00017	0.447
LIG_SH2_STAT5	834	837	PF00017	0.450
LIG_SH2_STAT6	264	268	PF00017	0.287
LIG_SH3_3	22	28	PF00018	0.399
LIG_SH3_3	247	253	PF00018	0.336
LIG_SH3_3	342	348	PF00018	0.503
LIG_SH3_3	724	730	PF00018	0.444
LIG_SH3_3	880	886	PF00018	0.448
LIG_SUMO_SIM_anti_2	145	151	PF11976	0.430
LIG_SUMO_SIM_anti_2	381	387	PF11976	0.417
LIG_SUMO_SIM_anti_2	973	978	PF11976	0.430
LIG_SUMO_SIM_par_1	145	151	PF11976	0.430
LIG_SUMO_SIM_par_1	471	477	PF11976	0.423
LIG_SUMO_SIM_par_1	771	776	PF11976	0.325
LIG_SUMO_SIM_par_1	885	892	PF11976	0.417
LIG_TRAF2_1	304	307	PF00917	0.388
LIG_TRAF2_1	573	576	PF00917	0.511
LIG_TYR_ITIM	727	732	PF00017	0.437
LIG_TYR_ITIM	870	875	PF00017	0.488
LIG_UBA3_1	241	248	PF00899	0.381
LIG_UBA3_1	519	527	PF00899	0.360
LIG_UBA3_1	748	756	PF00899	0.392
LIG_WRC_WIRS_1	312	317	PF05994	0.368
LIG_WRC_WIRS_1	362	367	PF05994	0.356
LIG_WRC_WIRS_1	469	474	PF05994	0.360
MOD_CDK_SPxxK_3	808	815	PF00069	0.511
MOD_CK1_1	159	165	PF00069	0.423
MOD_CK1_1	213	219	PF00069	0.669
MOD_CK1_1	290	296	PF00069	0.447
MOD_CK1_1	30	36	PF00069	0.443
MOD_CK1_1	311	317	PF00069	0.479
MOD_CK1_1	326	332	PF00069	0.502
MOD_CK1_1	337	343	PF00069	0.421
MOD_CK1_1	361	367	PF00069	0.355
MOD_CK1_1	468	474	PF00069	0.446
MOD_CK1_1	483	489	PF00069	0.463
MOD_CK1_1	538	544	PF00069	0.360
MOD_CK1_1	583	589	PF00069	0.490
MOD_CK1_1	689	695	PF00069	0.568
MOD_CK1_1	848	854	PF00069	0.543
MOD_CK1_1	950	956	PF00069	0.478
MOD_CK1_1	996	1002	PF00069	0.589
MOD_CK2_1	103	109	PF00069	0.417
MOD_CK2_1	268	274	PF00069	0.483
MOD_CK2_1	276	282	PF00069	0.530
MOD_CK2_1	301	307	PF00069	0.352
MOD_CK2_1	378	384	PF00069	0.430
MOD_CK2_1	394	400	PF00069	0.430
MOD_CK2_1	443	449	PF00069	0.375
MOD_CK2_1	553	559	PF00069	0.468
MOD_CK2_1	570	576	PF00069	0.348
MOD_CK2_1	664	670	PF00069	0.497
MOD_CK2_1	731	737	PF00069	0.464
MOD_CK2_1	803	809	PF00069	0.481
MOD_Cter_Amidation	356	359	PF01082	0.393
MOD_Cter_Amidation	409	412	PF01082	0.217
MOD_GlcNHglycan	238	241	PF01048	0.445
MOD_GlcNHglycan	325	328	PF01048	0.512
MOD_GlcNHglycan	336	339	PF01048	0.508
MOD_GlcNHglycan	421	424	PF01048	0.248
MOD_GlcNHglycan	539	543	PF01048	0.194
MOD_GlcNHglycan	572	575	PF01048	0.236
MOD_GlcNHglycan	576	579	PF01048	0.230
MOD_GlcNHglycan	702	705	PF01048	0.268
MOD_GlcNHglycan	845	848	PF01048	0.319
MOD_GSK3_1	206	213	PF00069	0.644
MOD_GSK3_1	226	233	PF00069	0.406
MOD_GSK3_1	23	30	PF00069	0.521
MOD_GSK3_1	252	259	PF00069	0.466
MOD_GSK3_1	357	364	PF00069	0.449
MOD_GSK3_1	390	397	PF00069	0.468
MOD_GSK3_1	468	475	PF00069	0.536
MOD_GSK3_1	553	560	PF00069	0.447
MOD_GSK3_1	570	577	PF00069	0.382
MOD_GSK3_1	580	587	PF00069	0.426
MOD_GSK3_1	664	671	PF00069	0.430
MOD_GSK3_1	682	689	PF00069	0.502
MOD_GSK3_1	702	709	PF00069	0.397
MOD_GSK3_1	782	789	PF00069	0.417
MOD_GSK3_1	885	892	PF00069	0.500
MOD_GSK3_1	9	16	PF00069	0.544
MOD_GSK3_1	903	910	PF00069	0.358
MOD_GSK3_1	947	954	PF00069	0.397
MOD_GSK3_1	989	996	PF00069	0.488
MOD_N-GLC_1	230	235	PF02516	0.312
MOD_N-GLC_1	290	295	PF02516	0.361
MOD_N-GLC_1	490	495	PF02516	0.252
MOD_N-GLC_2	399	401	PF02516	0.230
MOD_N-GLC_2	403	405	PF02516	0.204
MOD_NEK2_1	168	173	PF00069	0.346
MOD_NEK2_1	230	235	PF00069	0.427
MOD_NEK2_1	3	8	PF00069	0.490
MOD_NEK2_1	375	380	PF00069	0.330
MOD_NEK2_1	413	418	PF00069	0.444
MOD_NEK2_1	443	448	PF00069	0.484
MOD_NEK2_1	490	495	PF00069	0.396
MOD_NEK2_1	668	673	PF00069	0.572
MOD_NEK2_1	702	707	PF00069	0.508
MOD_NEK2_1	773	778	PF00069	0.278
MOD_NEK2_1	786	791	PF00069	0.369
MOD_NEK2_1	837	842	PF00069	0.474
MOD_NEK2_1	878	883	PF00069	0.392
MOD_NEK2_1	89	94	PF00069	0.476
MOD_NEK2_2	585	590	PF00069	0.446
MOD_NEK2_2	829	834	PF00069	0.430
MOD_NEK2_2	871	876	PF00069	0.473
MOD_OFUCOSY	944	951	PF10250	0.212
MOD_PIKK_1	3	9	PF00454	0.567
MOD_PIKK_1	490	496	PF00454	0.453
MOD_PIKK_1	903	909	PF00454	0.499
MOD_PK_1	358	364	PF00069	0.303
MOD_PKA_1	358	364	PF00069	0.303
MOD_PKA_1	903	909	PF00069	0.360
MOD_PKA_2	210	216	PF00069	0.411
MOD_PKA_2	357	363	PF00069	0.365
MOD_PKA_2	403	409	PF00069	0.472
MOD_PKA_2	419	425	PF00069	0.352
MOD_PKA_2	483	489	PF00069	0.490
MOD_PKA_2	570	576	PF00069	0.490
MOD_PKA_2	859	865	PF00069	0.417
MOD_PKA_2	903	909	PF00069	0.430
MOD_PKA_2	996	1002	PF00069	0.589
MOD_Plk_1	103	109	PF00069	0.417
MOD_Plk_1	230	236	PF00069	0.374
MOD_Plk_1	290	296	PF00069	0.449
MOD_Plk_1	375	381	PF00069	0.283
MOD_Plk_1	673	679	PF00069	0.468
MOD_Plk_2-3	1004	1010	PF00069	0.454
MOD_Plk_2-3	394	400	PF00069	0.511
MOD_Plk_4	156	162	PF00069	0.582
MOD_Plk_4	308	314	PF00069	0.429
MOD_Plk_4	358	364	PF00069	0.397
MOD_Plk_4	465	471	PF00069	0.494
MOD_Plk_4	585	591	PF00069	0.409
MOD_Plk_4	664	670	PF00069	0.444
MOD_Plk_4	682	688	PF00069	0.522
MOD_Plk_4	706	712	PF00069	0.456
MOD_Plk_4	782	788	PF00069	0.417
MOD_Plk_4	829	835	PF00069	0.417
MOD_Plk_4	885	891	PF00069	0.498
MOD_Plk_4	980	986	PF00069	0.473
MOD_ProDKin_1	148	154	PF00069	0.442
MOD_ProDKin_1	580	586	PF00069	0.496
MOD_ProDKin_1	641	647	PF00069	0.511
MOD_ProDKin_1	808	814	PF00069	0.511
MOD_ProDKin_1	905	911	PF00069	0.462
MOD_SUMO_for_1	220	223	PF00179	0.598
MOD_SUMO_for_1	926	929	PF00179	0.511
MOD_SUMO_for_1	990	993	PF00179	0.468
MOD_SUMO_rev_2	46	54	PF00179	0.430
MOD_SUMO_rev_2	483	490	PF00179	0.389
MOD_SUMO_rev_2	935	939	PF00179	0.360
TRG_DiLeu_BaEn_1	575	580	PF01217	0.514
TRG_DiLeu_BaEn_1	769	774	PF01217	0.436
TRG_DiLeu_BaLyEn_6	748	753	PF01217	0.427
TRG_ENDOCYTIC_2	17	20	PF00928	0.333
TRG_ENDOCYTIC_2	265	268	PF00928	0.280
TRG_ENDOCYTIC_2	312	315	PF00928	0.397
TRG_ENDOCYTIC_2	441	444	PF00928	0.468
TRG_ENDOCYTIC_2	49	52	PF00928	0.430
TRG_ENDOCYTIC_2	57	60	PF00928	0.430
TRG_ENDOCYTIC_2	729	732	PF00928	0.386
TRG_ENDOCYTIC_2	74	77	PF00928	0.385
TRG_ENDOCYTIC_2	834	837	PF00928	0.430
TRG_ENDOCYTIC_2	872	875	PF00928	0.488
TRG_ENDOCYTIC_2	894	897	PF00928	0.417
TRG_ENDOCYTIC_2	921	924	PF00928	0.417
TRG_ENDOCYTIC_2	959	962	PF00928	0.430
TRG_ER_diArg_1	192	194	PF00400	0.349
TRG_ER_diArg_1	202	205	PF00400	0.511
TRG_ER_diArg_1	367	369	PF00400	0.451
TRG_ER_diArg_1	411	413	PF00400	0.511
TRG_ER_diArg_1	607	609	PF00400	0.514
TRG_NES_CRM1_1	307	321	PF08389	0.459
TRG_NES_CRM1_1	465	479	PF08389	0.468
TRG_Pf-PMV_PEXEL_1	144	148	PF00026	0.217
TRG_Pf-PMV_PEXEL_1	609	613	PF00026	0.284

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6K5	Leptomonas seymouri	66%	98%
A0A0S4IMQ7	Bodo saltans	41%	100%
A0A3Q8IK49	Leishmania donovani	85%	100%
A0A3R7LRN7	Trypanosoma rangeli	47%	100%
A0KPG5	Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)	27%	100%
A0L7L5	Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)	28%	100%
A0Q809	Francisella tularensis subsp. novicida (strain U112)	23%	100%
A3N2Q0	Actinobacillus pleuropneumoniae serotype 5b (strain L20)	26%	100%
A4HL76	Leishmania braziliensis	26%	100%
A4IDG7	Leishmania infantum	85%	100%
A4IXL2	Francisella tularensis subsp. tularensis (strain WY96-3418)	23%	100%
A4SFT1	Chlorobium phaeovibrioides (strain DSM 265 / 1930)	26%	100%
A4SIL2	Aeromonas salmonicida (strain A449)	26%	100%
A5CDU2	Orientia tsutsugamushi (strain Boryong)	25%	100%
A5N8I5	Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)	24%	100%
A6VL76	Actinobacillus succinogenes (strain ATCC 55618 / DSM 22257 / CCUG 43843 / 130Z)	26%	100%
A6W1Q6	Marinomonas sp. (strain MWYL1)	26%	100%
A7N9Y6	Francisella tularensis subsp. holarctica (strain FTNF002-00 / FTA)	23%	100%
A8EZG1	Rickettsia canadensis (strain McKiel)	25%	100%
A8F164	Rickettsia massiliae (strain Mtu5)	23%	100%
A8GMX2	Rickettsia akari (strain Hartford)	24%	100%
A8GRI6	Rickettsia rickettsii (strain Sheila Smith)	23%	100%
A8GX86	Rickettsia bellii (strain OSU 85-389)	24%	100%
A8I275	Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)	26%	100%
A9WFZ9	Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)	27%	100%
B0BRS8	Actinobacillus pleuropneumoniae serotype 3 (strain JL03)	26%	100%
B0BWY8	Rickettsia rickettsii (strain Iowa)	23%	100%
B0CF30	Acaryochloris marina (strain MBIC 11017)	24%	100%
B0CIQ5	Brucella suis (strain ATCC 23445 / NCTC 10510)	25%	100%
B0UWV7	Histophilus somni (strain 2336)	25%	100%
B1N025	Leuconostoc citreum (strain KM20)	26%	100%
B2GB17	Limosilactobacillus fermentum (strain NBRC 3956 / LMG 18251)	23%	100%
B2SEQ6	Francisella tularensis subsp. mediasiatica (strain FSC147)	23%	100%
B3CQY2	Orientia tsutsugamushi (strain Ikeda)	25%	100%
B3H2J9	Actinobacillus pleuropneumoniae serotype 7 (strain AP76)	26%	100%
B3QPY5	Chlorobaculum parvum (strain DSM 263 / NCIMB 8327)	27%	100%
B9E1Z0	Clostridium kluyveri (strain NBRC 12016)	24%	100%
B9LB04	Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl)	27%	100%
C0QPF0	Persephonella marina (strain DSM 14350 / EX-H1)	25%	100%
C3PN02	Rickettsia africae (strain ESF-5)	24%	100%
C6DAK6	Pectobacterium carotovorum subsp. carotovorum (strain PC1)	24%	100%
D0A350	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	100%
E1BYJ2	Gallus gallus	28%	76%
E9ASW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
O65607	Arabidopsis thaliana	29%	94%
O74502	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	81%
P13705	Mus musculus	26%	93%
P25846	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
P61670	Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)	26%	100%
Q0BNM7	Francisella tularensis subsp. holarctica (strain OSU18)	23%	100%
Q0BV38	Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)	27%	100%
Q0I1B8	Haemophilus somnus (strain 129Pt)	25%	100%
Q14GB1	Francisella tularensis subsp. tularensis (strain FSC 198)	23%	100%
Q1MMA5	Rhizobium leguminosarum bv. viciae (strain 3841)	26%	100%
Q1QQJ4	Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)	25%	100%
Q1RJJ5	Rickettsia bellii (strain RML369-C)	24%	100%
Q1WT15	Ligilactobacillus salivarius (strain UCC118)	24%	100%
Q21LB1	Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)	25%	100%
Q24X61	Desulfitobacterium hafniense (strain Y51)	26%	100%
Q28VY6	Jannaschia sp. (strain CCS1)	27%	100%
Q2A5B5	Francisella tularensis subsp. holarctica (strain LVS)	23%	100%
Q2KD76	Rhizobium etli (strain CFN 42 / ATCC 51251)	25%	100%
Q2RNG0	Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1)	30%	100%
Q2YB94	Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)	25%	100%
Q31F87	Hydrogenovibrio crunogenus (strain DSM 25203 / XCL-2)	23%	100%
Q3M892	Trichormus variabilis (strain ATCC 29413 / PCC 7937)	24%	100%
Q3SVD4	Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255)	25%	100%
Q3YSJ8	Ehrlichia canis (strain Jake)	24%	100%
Q46CE2	Methanosarcina barkeri (strain Fusaro / DSM 804)	25%	100%
Q47DJ8	Dechloromonas aromatica (strain RCB)	26%	100%
Q47WN0	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	24%	100%
Q4Q1M8	Leishmania major	85%	100%
Q4UM86	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)	24%	100%
Q5NEV8	Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)	23%	100%
Q5NYP9	Aromatoleum aromaticum (strain EbN1)	27%	100%
Q6BW83	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	23%	99%
Q6CSR1	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	24%	99%
Q6G542	Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1)	24%	100%
Q7NRW7	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	27%	100%
Q7VKA1	Haemophilus ducreyi (strain 35000HP / ATCC 700724)	26%	100%
Q7W880	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	26%	100%
Q7WLT5	Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)	26%	100%
Q8KCC0	Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)	27%	100%
Q8TTB4	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	27%	100%
Q8UIF2	Agrobacterium fabrum (strain C58 / ATCC 33970)	26%	100%
Q92IL9	Rickettsia conorii (strain ATCC VR-613 / Malish 7)	24%	100%
Q9VUM0	Drosophila melanogaster	29%	85%
V5DCH4	Trypanosoma cruzi	48%	100%