Putative DEAD box RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DEAD box RNA helicase, putative

Species:

Leishmania braziliensis

UniProt:

A4HP48_LEIBR

TriTrypDb:

LbrM.35.2030 , LBRM2903_350026700

Length:

654

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HP48

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HP48

Function

Biological processes
Term	Name	Level	Count
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	10	1
GO:0000470	maturation of LSU-rRNA	9	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006364	rRNA processing	8	1
GO:0006396	RNA processing	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0016070	RNA metabolic process	5	1
GO:0016072	rRNA metabolic process	7	1
GO:0034470	ncRNA processing	7	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034660	ncRNA metabolic process	6	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0046483	heterocycle metabolic process	3	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003723	RNA binding	4	11
GO:0003724	RNA helicase activity	3	11
GO:0003743	translation initiation factor activity	4	7
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008135	translation factor activity, RNA binding	3	7
GO:0008186	ATP-dependent activity, acting on RNA	2	11
GO:0016787	hydrolase activity	2	8
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0045182	translation regulator activity	1	7
GO:0090079	translation regulator activity, nucleic acid binding	2	7
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140098	catalytic activity, acting on RNA	3	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	26	28	PF00675	0.539
CLV_NRD_NRD_1	31	33	PF00675	0.554
CLV_NRD_NRD_1	403	405	PF00675	0.283
CLV_NRD_NRD_1	635	637	PF00675	0.570
CLV_NRD_NRD_1	85	87	PF00675	0.720
CLV_PCSK_FUR_1	27	31	PF00082	0.433
CLV_PCSK_KEX2_1	112	114	PF00082	0.688
CLV_PCSK_KEX2_1	29	31	PF00082	0.547
CLV_PCSK_KEX2_1	634	636	PF00082	0.538
CLV_PCSK_KEX2_1	645	647	PF00082	0.515
CLV_PCSK_KEX2_1	79	81	PF00082	0.656
CLV_PCSK_KEX2_1	83	85	PF00082	0.653
CLV_PCSK_PC1ET2_1	112	114	PF00082	0.726
CLV_PCSK_PC1ET2_1	29	31	PF00082	0.517
CLV_PCSK_PC1ET2_1	634	636	PF00082	0.543
CLV_PCSK_PC1ET2_1	645	647	PF00082	0.513
CLV_PCSK_PC1ET2_1	79	81	PF00082	0.680
CLV_PCSK_PC1ET2_1	83	85	PF00082	0.655
CLV_PCSK_PC7_1	27	33	PF00082	0.502
CLV_PCSK_PC7_1	80	86	PF00082	0.793
CLV_PCSK_SKI1_1	112	116	PF00082	0.693
CLV_PCSK_SKI1_1	198	202	PF00082	0.163
CLV_PCSK_SKI1_1	254	258	PF00082	0.214
CLV_PCSK_SKI1_1	308	312	PF00082	0.214
CLV_PCSK_SKI1_1	405	409	PF00082	0.231
CLV_PCSK_SKI1_1	447	451	PF00082	0.225
CLV_PCSK_SKI1_1	580	584	PF00082	0.283
CLV_PCSK_SKI1_1	628	632	PF00082	0.504
DEG_SCF_FBW7_1	183	188	PF00400	0.394
DEG_SPOP_SBC_1	131	135	PF00917	0.592
DOC_CYCLIN_RxL_1	239	249	PF00134	0.425
DOC_CYCLIN_RxL_1	305	316	PF00134	0.515
DOC_CYCLIN_yClb1_LxF_4	506	512	PF00134	0.314
DOC_MAPK_gen_1	404	415	PF00069	0.414
DOC_MAPK_gen_1	501	511	PF00069	0.476
DOC_MAPK_MEF2A_6	280	289	PF00069	0.425
DOC_MAPK_MEF2A_6	308	315	PF00069	0.414
DOC_MAPK_MEF2A_6	364	371	PF00069	0.333
DOC_MAPK_MEF2A_6	408	415	PF00069	0.414
DOC_MAPK_NFAT4_5	308	316	PF00069	0.414
DOC_PP1_RVXF_1	208	215	PF00149	0.414
DOC_PP1_RVXF_1	357	363	PF00149	0.332
DOC_PP1_RVXF_1	408	415	PF00149	0.414
DOC_PP2B_LxvP_1	11	14	PF13499	0.493
DOC_PP2B_LxvP_1	472	475	PF13499	0.414
DOC_PP4_FxxP_1	214	217	PF00568	0.414
DOC_PP4_FxxP_1	483	486	PF00568	0.425
DOC_PP4_FxxP_1	511	514	PF00568	0.317
DOC_USP7_MATH_1	100	104	PF00917	0.675
DOC_USP7_MATH_1	124	128	PF00917	0.768
DOC_USP7_MATH_1	131	135	PF00917	0.630
DOC_USP7_MATH_1	145	149	PF00917	0.488
DOC_USP7_MATH_1	185	189	PF00917	0.515
DOC_USP7_MATH_1	6	10	PF00917	0.570
DOC_USP7_MATH_1	614	618	PF00917	0.518
DOC_USP7_UBL2_3	149	153	PF12436	0.598
DOC_USP7_UBL2_3	405	409	PF12436	0.426
DOC_USP7_UBL2_3	641	645	PF12436	0.604
DOC_USP7_UBL2_3	79	83	PF12436	0.765
DOC_WW_Pin1_4	107	112	PF00397	0.524
DOC_WW_Pin1_4	120	125	PF00397	0.576
DOC_WW_Pin1_4	132	137	PF00397	0.699
DOC_WW_Pin1_4	181	186	PF00397	0.504
DOC_WW_Pin1_4	288	293	PF00397	0.414
DOC_WW_Pin1_4	362	367	PF00397	0.475
LIG_14-3-3_CanoR_1	113	117	PF00244	0.559
LIG_14-3-3_CanoR_1	341	345	PF00244	0.418
LIG_14-3-3_CanoR_1	359	363	PF00244	0.415
LIG_14-3-3_CanoR_1	418	424	PF00244	0.414
LIG_14-3-3_CanoR_1	447	452	PF00244	0.416
LIG_14-3-3_CanoR_1	560	567	PF00244	0.268
LIG_Actin_WH2_2	545	562	PF00022	0.268
LIG_BIR_II_1	1	5	PF00653	0.726
LIG_BRCT_BRCA1_1	126	130	PF00533	0.496
LIG_BRCT_BRCA1_1	261	265	PF00533	0.414
LIG_BRCT_BRCA1_1	419	423	PF00533	0.481
LIG_Clathr_ClatBox_1	312	316	PF01394	0.515
LIG_CORNRBOX	166	174	PF00104	0.235
LIG_deltaCOP1_diTrp_1	476	483	PF00928	0.420
LIG_FHA_1	152	158	PF00498	0.340
LIG_FHA_1	231	237	PF00498	0.414
LIG_FHA_1	239	245	PF00498	0.414
LIG_FHA_1	305	311	PF00498	0.433
LIG_FHA_1	349	355	PF00498	0.414
LIG_FHA_1	462	468	PF00498	0.417
LIG_FHA_1	533	539	PF00498	0.431
LIG_FHA_2	115	121	PF00498	0.494
LIG_FHA_2	18	24	PF00498	0.646
LIG_FHA_2	350	356	PF00498	0.414
LIG_LIR_Apic_2	211	217	PF02991	0.418
LIG_LIR_Gen_1	177	186	PF02991	0.328
LIG_LIR_Gen_1	426	436	PF02991	0.425
LIG_LIR_Gen_1	448	458	PF02991	0.414
LIG_LIR_Nem_3	159	164	PF02991	0.381
LIG_LIR_Nem_3	177	183	PF02991	0.464
LIG_LIR_Nem_3	426	431	PF02991	0.440
LIG_LIR_Nem_3	448	454	PF02991	0.414
LIG_LIR_Nem_3	516	522	PF02991	0.315
LIG_NRBOX	251	257	PF00104	0.414
LIG_PCNA_yPIPBox_3	540	553	PF02747	0.394
LIG_Pex14_1	479	483	PF04695	0.414
LIG_Rb_pABgroove_1	518	526	PF01858	0.378
LIG_REV1ctd_RIR_1	412	422	PF16727	0.414
LIG_SH2_CRK	108	112	PF00017	0.503
LIG_SH2_CRK	161	165	PF00017	0.370
LIG_SH2_CRK	400	404	PF00017	0.414
LIG_SH2_NCK_1	524	528	PF00017	0.367
LIG_SH2_PTP2	430	433	PF00017	0.414
LIG_SH2_SRC	430	433	PF00017	0.414
LIG_SH2_SRC	524	527	PF00017	0.383
LIG_SH2_STAP1	534	538	PF00017	0.408
LIG_SH2_STAT5	387	390	PF00017	0.299
LIG_SH2_STAT5	430	433	PF00017	0.427
LIG_SH2_STAT5	492	495	PF00017	0.417
LIG_SH2_STAT5	522	525	PF00017	0.350
LIG_SH2_STAT5	534	537	PF00017	0.431
LIG_SH2_STAT5	558	561	PF00017	0.302
LIG_SH2_STAT5	570	573	PF00017	0.302
LIG_SH3_2	486	491	PF14604	0.425
LIG_SH3_3	133	139	PF00018	0.700
LIG_SH3_3	286	292	PF00018	0.524
LIG_SH3_3	483	489	PF00018	0.425
LIG_SUMO_SIM_anti_2	332	338	PF11976	0.414
LIG_SUMO_SIM_anti_2	62	72	PF11976	0.492
LIG_SUMO_SIM_par_1	285	291	PF11976	0.439
LIG_SUMO_SIM_par_1	311	317	PF11976	0.415
LIG_TRAF2_1	21	24	PF00917	0.464
LIG_TRAF2_1	514	517	PF00917	0.453
LIG_TYR_ITIM	398	403	PF00017	0.414
LIG_UBA3_1	252	257	PF00899	0.414
LIG_UBA3_1	295	300	PF00899	0.414
MOD_CDC14_SPxK_1	110	113	PF00782	0.500
MOD_CDC14_SPxK_1	291	294	PF00782	0.439
MOD_CDK_SPK_2	107	112	PF00069	0.503
MOD_CDK_SPxK_1	107	113	PF00069	0.504
MOD_CDK_SPxK_1	288	294	PF00069	0.414
MOD_CK1_1	125	131	PF00069	0.673
MOD_CK1_1	230	236	PF00069	0.492
MOD_CK1_1	370	376	PF00069	0.555
MOD_CK1_1	417	423	PF00069	0.483
MOD_CK1_1	573	579	PF00069	0.278
MOD_CK1_1	617	623	PF00069	0.504
MOD_CK2_1	114	120	PF00069	0.651
MOD_CK2_1	169	175	PF00069	0.351
MOD_CK2_1	17	23	PF00069	0.541
MOD_CK2_1	349	355	PF00069	0.437
MOD_CK2_1	617	623	PF00069	0.481
MOD_GlcNHglycan	103	106	PF01048	0.687
MOD_GlcNHglycan	124	127	PF01048	0.706
MOD_GlcNHglycan	171	174	PF01048	0.460
MOD_GlcNHglycan	224	227	PF01048	0.288
MOD_GlcNHglycan	346	349	PF01048	0.214
MOD_GlcNHglycan	447	450	PF01048	0.225
MOD_GlcNHglycan	458	461	PF01048	0.238
MOD_GlcNHglycan	561	564	PF01048	0.285
MOD_GlcNHglycan	611	614	PF01048	0.475
MOD_GlcNHglycan	650	653	PF01048	0.529
MOD_GSK3_1	120	127	PF00069	0.682
MOD_GSK3_1	156	163	PF00069	0.475
MOD_GSK3_1	181	188	PF00069	0.365
MOD_GSK3_1	340	347	PF00069	0.431
MOD_GSK3_1	358	365	PF00069	0.433
MOD_GSK3_1	413	420	PF00069	0.487
MOD_GSK3_1	74	81	PF00069	0.734
MOD_LATS_1	445	451	PF00433	0.414
MOD_N-GLC_1	230	235	PF02516	0.232
MOD_N-GLC_1	259	264	PF02516	0.214
MOD_N-GLC_1	648	653	PF02516	0.534
MOD_NEK2_1	1	6	PF00069	0.594
MOD_NEK2_1	130	135	PF00069	0.520
MOD_NEK2_1	151	156	PF00069	0.586
MOD_NEK2_1	259	264	PF00069	0.425
MOD_NEK2_1	344	349	PF00069	0.436
MOD_NEK2_1	414	419	PF00069	0.433
MOD_NEK2_1	552	557	PF00069	0.310
MOD_NEK2_1	559	564	PF00069	0.245
MOD_NEK2_1	572	577	PF00069	0.118
MOD_NEK2_1	607	612	PF00069	0.451
MOD_NEK2_2	358	363	PF00069	0.336
MOD_PIKK_1	346	352	PF00454	0.414
MOD_PIKK_1	607	613	PF00454	0.451
MOD_PKA_1	112	118	PF00069	0.504
MOD_PKA_2	112	118	PF00069	0.561
MOD_PKA_2	227	233	PF00069	0.487
MOD_PKA_2	340	346	PF00069	0.414
MOD_PKA_2	358	364	PF00069	0.341
MOD_PKA_2	417	423	PF00069	0.483
MOD_PKA_2	559	565	PF00069	0.268
MOD_Plk_1	140	146	PF00069	0.435
MOD_Plk_1	532	538	PF00069	0.387
MOD_Plk_1	639	645	PF00069	0.433
MOD_Plk_1	65	71	PF00069	0.490
MOD_Plk_2-3	376	382	PF00069	0.387
MOD_Plk_2-3	87	93	PF00069	0.749
MOD_Plk_4	261	267	PF00069	0.481
MOD_Plk_4	340	346	PF00069	0.446
MOD_Plk_4	447	453	PF00069	0.414
MOD_Plk_4	65	71	PF00069	0.526
MOD_ProDKin_1	107	113	PF00069	0.525
MOD_ProDKin_1	120	126	PF00069	0.578
MOD_ProDKin_1	132	138	PF00069	0.758
MOD_ProDKin_1	181	187	PF00069	0.402
MOD_ProDKin_1	288	294	PF00069	0.414
MOD_ProDKin_1	362	368	PF00069	0.474
MOD_SUMO_rev_2	172	181	PF00179	0.315
MOD_SUMO_rev_2	199	206	PF00179	0.414
TRG_DiLeu_BaEn_1	332	337	PF01217	0.414
TRG_DiLeu_BaEn_1	393	398	PF01217	0.306
TRG_DiLeu_BaLyEn_6	291	296	PF01217	0.414
TRG_DiLeu_BaLyEn_6	392	397	PF01217	0.293
TRG_ENDOCYTIC_2	161	164	PF00928	0.348
TRG_ENDOCYTIC_2	400	403	PF00928	0.431
TRG_ENDOCYTIC_2	430	433	PF00928	0.414
TRG_ENDOCYTIC_2	451	454	PF00928	0.414
TRG_ER_diArg_1	30	32	PF00400	0.609
TRG_ER_diArg_1	84	86	PF00400	0.690
TRG_NES_CRM1_1	589	601	PF08389	0.263
TRG_NLS_Bipartite_1	618	638	PF00514	0.403
TRG_NLS_MonoCore_2	26	31	PF00514	0.532
TRG_NLS_MonoExtC_3	26	31	PF00514	0.557
TRG_NLS_MonoExtC_3	617	623	PF00514	0.462
TRG_NLS_MonoExtN_4	27	33	PF00514	0.531
TRG_NLS_MonoExtN_4	405	412	PF00514	0.414
TRG_NLS_MonoExtN_4	631	638	PF00514	0.405
TRG_Pf-PMV_PEXEL_1	198	203	PF00026	0.225
TRG_Pf-PMV_PEXEL_1	242	247	PF00026	0.214
TRG_Pf-PMV_PEXEL_1	521	525	PF00026	0.243

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7J1	Leptomonas seymouri	38%	73%
A0A0N0P942	Leptomonas seymouri	29%	75%
A0A0N1I6K5	Leptomonas seymouri	81%	100%
A0A0N1PCZ7	Leptomonas seymouri	24%	100%
A0A0S4IWD0	Bodo saltans	76%	100%
A0A0S4KKU4	Bodo saltans	37%	94%
A0A1X0NJH3	Trypanosomatidae	25%	100%
A0A1X0NMD6	Trypanosomatidae	30%	80%
A0A1X0NQS6	Trypanosomatidae	28%	100%
A0A1X0P3K1	Trypanosomatidae	37%	70%
A0A1X0P5E1	Trypanosomatidae	33%	92%
A0A1X0P7S4	Trypanosomatidae	70%	100%
A0A3Q8IC45	Leishmania donovani	27%	100%
A0A3Q8ID91	Leishmania donovani	33%	100%
A0A3R7KAR1	Trypanosoma rangeli	30%	100%
A0A3R7M1K3	Trypanosoma rangeli	36%	91%
A0A3R7NGQ1	Trypanosoma rangeli	69%	100%
A0A3S5H7C7	Leishmania donovani	24%	100%
A0A3S7X1H1	Leishmania donovani	38%	73%
A0A3S7X579	Leishmania donovani	29%	100%
A0A3S7X5R1	Leishmania donovani	32%	85%
A0A3S7XAN8	Leishmania donovani	87%	99%
A0A3S7XAT8	Leishmania donovani	33%	100%
A0A422NYB4	Trypanosoma rangeli	36%	77%
A1CB55	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	29%	87%
A1CIQ5	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	51%	100%
A1CL59	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	31%	100%
A1CTZ2	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	41%	79%
A1CTZ6	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	29%	70%
A1CW14	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	44%	100%
A1D699	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	32%	100%
A1DE84	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	31%	86%
A2Q9T6	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	53%	100%
A2QE29	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	31%	100%
A2RA55	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	31%	85%
A3GGE9	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	37%	85%
A3LNR6	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	53%	100%
A3LWH3	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	28%	89%
A3LX02	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	30%	100%
A4H460	Leishmania braziliensis	30%	95%
A4HGH8	Leishmania braziliensis	39%	73%
A4HGR1	Leishmania braziliensis	30%	100%
A4HK38	Leishmania braziliensis	30%	100%
A4HKL3	Leishmania braziliensis	35%	85%
A4HSE3	Leishmania infantum	30%	96%
A4HT33	Leishmania infantum	35%	100%
A4HZF8	Leishmania infantum	27%	100%
A4I3L0	Leishmania infantum	38%	73%
A4I3T6	Leishmania infantum	33%	100%
A4I7M5	Leishmania infantum	29%	100%
A4I846	Leishmania infantum	32%	85%
A4IDF5	Leishmania infantum	87%	99%
A4IDF6	Leishmania infantum	33%	100%
A4R8B5	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	49%	100%
A4RGU2	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	38%	82%
A5DAR2	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	29%	88%
A5DGM4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	33%	100%
A5DID7	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	51%	100%
A5DLF4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	35%	87%
A5E2I8	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	31%	100%
A5E2Z9	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	54%	100%
A5E3K3	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	37%	84%
A6R918	Ajellomyces capsulatus (strain NAm1 / WU24)	32%	97%
A6RMZ2	Botryotinia fuckeliana (strain B05.10)	31%	100%
A6RSH5	Botryotinia fuckeliana (strain B05.10)	31%	75%
A6ZPU3	Saccharomyces cerevisiae (strain YJM789)	38%	85%
A6ZZY8	Saccharomyces cerevisiae (strain YJM789)	28%	88%
A7A237	Saccharomyces cerevisiae (strain YJM789)	34%	100%
A7ESL8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	38%	81%
A7F2S3	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	30%	100%
A7F8V8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	32%	75%
A7TJ71	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	38%	85%
A7TJS7	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	30%	100%
C9ZKU1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	74%
C9ZPV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	79%
D0A331	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	83%	100%
D0A6Z3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0A872	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
E9AH36	Leishmania infantum	24%	100%
E9AJG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9AKB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	96%
E9ASV6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	99%
E9ASV7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9AVE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AWL4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9AZV0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	73%
E9B028	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9B2I0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B304	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	84%
O60173	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	92%
O74764	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
O80792	Arabidopsis thaliana	28%	77%
P0CQ82	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	37%	76%
P0CQ83	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	37%	76%
P0CQ84	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	51%	100%
P0CQ85	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	51%	100%
P20448	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	38%	85%
P25808	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	100%
P34640	Caenorhabditis elegans	31%	100%
P36120	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	88%
P57453	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	32%	100%
P96614	Bacillus subtilis (strain 168)	31%	100%
Q03532	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	52%	100%
Q09916	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	52%	100%
Q0CF43	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	30%	85%
Q0CQF3	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	32%	100%
Q0CZS8	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	49%	100%
Q0D622	Oryza sativa subsp. japonica	39%	85%
Q0DBS1	Oryza sativa subsp. japonica	46%	100%
Q0DBU5	Oryza sativa subsp. japonica	33%	100%
Q0DLB9	Oryza sativa subsp. japonica	32%	100%
Q0U8V9	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	31%	100%
Q0UMB9	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	40%	81%
Q0UP45	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	32%	100%
Q0UR48	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	51%	100%
Q13206	Homo sapiens	40%	75%
Q1E1R7	Coccidioides immitis (strain RS)	32%	100%
Q1E9T9	Coccidioides immitis (strain RS)	30%	85%
Q1EA54	Coccidioides immitis (strain RS)	52%	100%
Q1EB31	Coccidioides immitis (strain RS)	40%	81%
Q2GMX1	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	52%	100%
Q2GV49	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	34%	100%
Q2GZU7	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	33%	81%
Q2H1Q8	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	35%	100%
Q2H2J1	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	40%	79%
Q2NL08	Bos taurus	39%	100%
Q2UBZ5	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	33%	100%
Q2UE66	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	32%	86%
Q2UHB7	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	40%	82%
Q2UST1	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	31%	100%
Q2UUN6	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	50%	100%
Q4HVW2	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	32%	100%
Q4HZ68	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	30%	88%
Q4IEK8	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	52%	100%
Q4PEX7	Ustilago maydis (strain 521 / FGSC 9021)	29%	100%
Q4Q1N9	Leishmania major	33%	100%
Q4Q1P0	Leishmania major	87%	100%
Q4Q552	Leishmania major	36%	85%
Q4Q5M6	Leishmania major	30%	100%
Q4Q858	Leishmania major	33%	100%
Q4Q8D5	Leishmania major	39%	73%
Q4QC38	Leishmania major	27%	100%
Q4WM60	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	40%	83%
Q4WQM4	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	43%	100%
Q4WV71	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	29%	86%
Q4WYJ7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	32%	100%
Q54EC2	Dictyostelium discoideum	34%	99%
Q54Q94	Dictyostelium discoideum	37%	74%
Q54S03	Dictyostelium discoideum	53%	100%
Q59N29	Candida albicans (strain SC5314 / ATCC MYA-2876)	30%	100%
Q59S50	Candida albicans (strain SC5314 / ATCC MYA-2876)	27%	90%
Q5AF95	Candida albicans (strain SC5314 / ATCC MYA-2876)	37%	85%
Q5AK59	Candida albicans (strain SC5314 / ATCC MYA-2876)	53%	100%
Q5APM7	Candida albicans (strain SC5314 / ATCC MYA-2876)	31%	98%
Q5B3H7	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	32%	100%
Q5B8F4	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	32%	100%
Q5BBY1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	53%	100%
Q5BFU1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	39%	81%
Q5BGX6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	32%	84%
Q5ZJF6	Gallus gallus	38%	75%
Q5ZLN8	Gallus gallus	40%	100%
Q61R02	Caenorhabditis briggsae	31%	100%
Q65N62	Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)	31%	100%
Q6AZV7	Xenopus laevis	38%	100%
Q6BH93	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	50%	100%
Q6BKH3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	28%	82%
Q6BSM3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	31%	100%
Q6C193	Yarrowia lipolytica (strain CLIB 122 / E 150)	32%	100%
Q6C7D2	Yarrowia lipolytica (strain CLIB 122 / E 150)	52%	100%
Q6C835	Yarrowia lipolytica (strain CLIB 122 / E 150)	31%	82%
Q6CGD1	Yarrowia lipolytica (strain CLIB 122 / E 150)	38%	88%
Q6CK32	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	29%	88%
Q6CN92	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	32%	100%
Q6CRF4	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	38%	85%
Q6CXB7	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	52%	100%
Q6FIL3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	54%	100%
Q6FKS8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	33%	100%
Q6FPT7	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	36%	85%
Q6NZQ2	Mus musculus	31%	95%
Q6ZPL9	Mus musculus	39%	100%
Q74Z73	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	52%	100%
Q750F8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	31%	100%
Q754J2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	29%	92%
Q75C76	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	36%	86%
Q761Z9	Oryza sativa subsp. japonica	35%	100%
Q7RZ35	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	40%	79%
Q7S2N9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	51%	100%
Q7S873	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	31%	80%
Q7XJN0	Arabidopsis thaliana	33%	100%
Q80Y44	Mus musculus	40%	75%
Q84T03	Oryza sativa subsp. japonica	47%	100%
Q86B47	Drosophila melanogaster	30%	67%
Q873H9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	33%	100%
Q8GXD6	Arabidopsis thaliana	34%	100%
Q8JHJ2	Danio rerio	39%	100%
Q8K363	Mus musculus	53%	99%
Q8K4L0	Mus musculus	31%	75%
Q8K9H6	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	31%	100%
Q8NHQ9	Homo sapiens	40%	100%
Q8SR49	Encephalitozoon cuniculi (strain GB-M1)	32%	100%
Q94C75	Arabidopsis thaliana	32%	100%
Q96GQ7	Homo sapiens	31%	82%
Q9FFQ1	Arabidopsis thaliana	33%	91%
Q9FLB0	Arabidopsis thaliana	34%	100%
Q9FNM7	Arabidopsis thaliana	33%	77%
Q9H8H2	Homo sapiens	31%	77%
Q9LIH9	Arabidopsis thaliana	46%	100%
Q9NVP1	Homo sapiens	53%	98%
Q9SA27	Arabidopsis thaliana	32%	100%
Q9SB89	Arabidopsis thaliana	46%	100%
Q9UTP9	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	89%
Q9VD51	Drosophila melanogaster	52%	96%
Q9VHU1	Drosophila melanogaster	33%	100%
Q9Y7C4	Candida albicans (strain SC5314 / ATCC MYA-2876)	30%	100%
V5DAZ9	Trypanosoma cruzi	37%	69%
V5DCA1	Trypanosoma cruzi	37%	91%
V5DKV2	Trypanosoma cruzi	70%	100%