LeishMANIAdb
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SCP domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
SCP domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HNX9_LEIBR
TriTrypDb:
LbrM.35.1320 , LBRM2903_350019000
Length:
140

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HNX9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNX9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 122 124 PF00675 0.583
CLV_NRD_NRD_1 2 4 PF00675 0.510
CLV_NRD_NRD_1 66 68 PF00675 0.510
CLV_PCSK_KEX2_1 122 124 PF00082 0.560
CLV_PCSK_KEX2_1 2 4 PF00082 0.510
CLV_PCSK_SKI1_1 118 122 PF00082 0.627
CLV_PCSK_SKI1_1 2 6 PF00082 0.640
CLV_PCSK_SKI1_1 35 39 PF00082 0.691
DEG_Nend_UBRbox_1 1 4 PF02207 0.514
DEG_SCF_FBW7_1 17 24 PF00400 0.619
DOC_MAPK_gen_1 2 10 PF00069 0.505
DOC_MAPK_MEF2A_6 2 10 PF00069 0.420
DOC_WW_Pin1_4 17 22 PF00397 0.551
LIG_14-3-3_CanoR_1 2 7 PF00244 0.534
LIG_APCC_ABBA_1 94 99 PF00400 0.433
LIG_BRCT_BRCA1_1 128 132 PF00533 0.569
LIG_FHA_1 3 9 PF00498 0.502
LIG_FHA_2 42 48 PF00498 0.491
LIG_LIR_Gen_1 79 86 PF02991 0.440
LIG_LIR_Nem_3 79 83 PF02991 0.455
LIG_SH2_GRB2like 40 43 PF00017 0.507
LIG_SH2_NCK_1 97 101 PF00017 0.477
LIG_SH2_SRC 80 83 PF00017 0.517
LIG_SH2_STAT5 40 43 PF00017 0.583
LIG_SH2_STAT5 82 85 PF00017 0.449
LIG_TRAF2_1 44 47 PF00917 0.455
MOD_CDK_SPxK_1 17 23 PF00069 0.619
MOD_CK1_1 72 78 PF00069 0.415
MOD_CK2_1 41 47 PF00069 0.495
MOD_GlcNHglycan 126 131 PF01048 0.558
MOD_GSK3_1 17 24 PF00069 0.598
MOD_GSK3_1 41 48 PF00069 0.537
MOD_GSK3_1 72 79 PF00069 0.357
MOD_N-GLC_1 41 46 PF02516 0.500
MOD_PIKK_1 72 78 PF00454 0.532
MOD_PKA_1 2 8 PF00069 0.612
MOD_PKA_2 2 8 PF00069 0.572
MOD_Plk_1 41 47 PF00069 0.495
MOD_Plk_1 69 75 PF00069 0.437
MOD_ProDKin_1 17 23 PF00069 0.552
MOD_SUMO_rev_2 46 50 PF00179 0.500
TRG_DiLeu_BaEn_4 69 75 PF01217 0.437
TRG_ENDOCYTIC_2 111 114 PF00928 0.418
TRG_ENDOCYTIC_2 80 83 PF00928 0.517
TRG_ER_diArg_1 1 3 PF00400 0.519
TRG_Pf-PMV_PEXEL_1 43 47 PF00026 0.407

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I3V3 Leptomonas seymouri 84% 100%
A0A0S4J8Z0 Bodo saltans 53% 100%
A0A1X0P9F9 Trypanosomatidae 72% 98%
A0A3Q8ING9 Leishmania donovani 89% 100%
A4ICL5 Leishmania infantum 89% 100%
D0A2U5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 75% 100%
E9ASN9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4Q1V7 Leishmania major 89% 100%
V5BUX9 Trypanosoma cruzi 75% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS