Protein MEMO1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Protein MEMO1

Gene product:

AmmeMemoRadiSam system protein B, putative

Species:

Leishmania braziliensis

UniProt:

A4HNX6_LEIBR

TriTrypDb:

LbrM.35.1290 , LBRM2903_350018700

Length:

328

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Show entries

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A4HNX6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNX6

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	146	148	PF00675	0.319
CLV_NRD_NRD_1	261	263	PF00675	0.365
CLV_PCSK_KEX2_1	146	148	PF00082	0.367
CLV_PCSK_KEX2_1	261	263	PF00082	0.302
CLV_PCSK_SKI1_1	129	133	PF00082	0.329
CLV_PCSK_SKI1_1	214	218	PF00082	0.319
CLV_PCSK_SKI1_1	34	38	PF00082	0.288
CLV_PCSK_SKI1_1	5	9	PF00082	0.456
DEG_SCF_FBW7_1	157	163	PF00400	0.395
DOC_CKS1_1	113	118	PF01111	0.310

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKG9	Leptomonas seymouri	71%	100%
A0A1X0P836	Trypanosomatidae	49%	100%
A0A3Q8IIU9	Leishmania donovani	84%	89%
A0A422NTW6	Trypanosoma rangeli	49%	100%
A1RTJ4	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	23%	100%
A3MS51	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	24%	100%
A4FWD2	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	24%	100%
A4ICL8	Leishmania infantum	84%	89%
A4WH12	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	24%	100%
A4YIM6	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	22%	100%

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