Flagellar C1a complex subunit C1a-32

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Flagellar C1a complex subunit C1a-32, putative

Species:

Leishmania braziliensis

UniProt:

A4HNW4_LEIBR

TriTrypDb:

LbrM.35.1170 , LBRM2903_350017500

Length:

286

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	3
GO:0005930	axoneme	2	1
GO:0031514	motile cilium	5	3
GO:0042995	cell projection	2	3
GO:0043226	organelle	2	3
GO:0043227	membrane-bounded organelle	3	3
GO:0110165	cellular anatomical entity	1	4
GO:0120025	plasma membrane bounded cell projection	3	3

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Expansion

Sequence features

A4HNW4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNW4

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	238	242	PF00656	0.491
CLV_NRD_NRD_1	284	286	PF00675	0.628
CLV_PCSK_KEX2_1	218	220	PF00082	0.569
CLV_PCSK_KEX2_1	284	286	PF00082	0.614
CLV_PCSK_PC1ET2_1	218	220	PF00082	0.434
CLV_PCSK_PC1ET2_1	284	286	PF00082	0.630
DEG_APCC_DBOX_1	232	240	PF00400	0.449
DOC_MAPK_gen_1	245	253	PF00069	0.350
DOC_MAPK_MEF2A_6	48	57	PF00069	0.517
DOC_USP7_MATH_1	51	55	PF00917	0.339

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PE82	Leptomonas seymouri	68%	100%
A0A0S4JAR9	Bodo saltans	36%	95%
A0A1X0P8D5	Trypanosomatidae	41%	100%
A0A3Q8IVT9	Leishmania donovani	84%	100%
A0A3R7MW02	Trypanosoma rangeli	42%	100%
A4ICN0	Leishmania infantum	84%	100%
D0A2T2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
E9ASM4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%
Q4Q1X2	Leishmania major	83%	100%
V5BQE4	Trypanosoma cruzi	46%	100%

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