DNA helicase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

DNA helicase

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HNW1_LEIBR

TriTrypDb:

LbrM.35.1140 , LBRM2903_350017400

Length:

197

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HNW1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNW1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	138	142	PF00656	0.818
CLV_NRD_NRD_1	34	36	PF00675	0.637
CLV_PCSK_FUR_1	32	36	PF00082	0.645
CLV_PCSK_KEX2_1	188	190	PF00082	0.689
CLV_PCSK_KEX2_1	34	36	PF00082	0.637
CLV_PCSK_PC1ET2_1	188	190	PF00082	0.689
CLV_PCSK_PC7_1	184	190	PF00082	0.658
CLV_PCSK_SKI1_1	112	116	PF00082	0.614
CLV_PCSK_SKI1_1	179	183	PF00082	0.631
CLV_PCSK_SKI1_1	184	188	PF00082	0.552
CLV_PCSK_SKI1_1	189	193	PF00082	0.545
CLV_PCSK_SKI1_1	28	32	PF00082	0.614
CLV_PCSK_SKI1_1	37	41	PF00082	0.460
DEG_APCC_DBOX_1	36	44	PF00400	0.612
DEG_Nend_UBRbox_3	1	3	PF02207	0.769
DOC_CYCLIN_RxL_1	176	187	PF00134	0.632
DOC_CYCLIN_yCln2_LP_2	60	66	PF00134	0.748
DOC_MAPK_gen_1	32	40	PF00069	0.630
DOC_MAPK_gen_1	54	61	PF00069	0.666
DOC_PP1_RVXF_1	177	184	PF00149	0.632
DOC_PP2B_LxvP_1	47	50	PF13499	0.650
DOC_USP7_MATH_1	158	162	PF00917	0.785
DOC_WW_Pin1_4	72	77	PF00397	0.726
LIG_14-3-3_CanoR_1	103	107	PF00244	0.613
LIG_14-3-3_CanoR_1	166	172	PF00244	0.662
LIG_14-3-3_CanoR_1	37	47	PF00244	0.615
LIG_14-3-3_CanoR_1	9	14	PF00244	0.724
LIG_APCC_ABBAyCdc20_2	103	109	PF00400	0.613
LIG_FHA_1	120	126	PF00498	0.747
LIG_FHA_1	75	81	PF00498	0.666
LIG_FHA_1	83	89	PF00498	0.454
LIG_FHA_2	149	155	PF00498	0.806
LIG_FHA_2	168	174	PF00498	0.318
LIG_FHA_2	39	45	PF00498	0.611
LIG_LIR_Gen_1	105	115	PF02991	0.605
LIG_LIR_Gen_1	82	92	PF02991	0.593
LIG_LIR_Nem_3	105	111	PF02991	0.607
LIG_LIR_Nem_3	82	87	PF02991	0.602
LIG_REV1ctd_RIR_1	180	188	PF16727	0.633
LIG_SH2_CRK	84	88	PF00017	0.591
LIG_SH2_STAP1	84	88	PF00017	0.591
LIG_SH2_STAT5	117	120	PF00017	0.634
LIG_SH2_STAT5	84	87	PF00017	0.595
LIG_SH3_3	70	76	PF00018	0.750
LIG_SUMO_SIM_anti_2	23	28	PF11976	0.597
MOD_CK1_1	135	141	PF00069	0.824
MOD_CK2_1	148	154	PF00069	0.807
MOD_CK2_1	158	164	PF00069	0.605
MOD_CK2_1	167	173	PF00069	0.321
MOD_Cter_Amidation	32	35	PF01082	0.656
MOD_GSK3_1	72	79	PF00069	0.712
MOD_GSK3_1	82	89	PF00069	0.422
MOD_GSK3_1	98	105	PF00069	0.341
MOD_N-GLC_1	1	6	PF02516	0.740
MOD_NEK2_1	1	6	PF00069	0.740
MOD_NEK2_1	119	124	PF00069	0.721
MOD_NEK2_1	190	195	PF00069	0.742
MOD_NEK2_1	38	43	PF00069	0.602
MOD_NEK2_1	92	97	PF00069	0.603
MOD_PIKK_1	132	138	PF00454	0.824
MOD_PIKK_1	74	80	PF00454	0.682
MOD_PIKK_1	82	88	PF00454	0.458
MOD_PKA_2	102	108	PF00069	0.617
MOD_Plk_1	20	26	PF00069	0.607
MOD_Plk_2-3	148	154	PF00069	0.807
MOD_Plk_4	102	108	PF00069	0.617
MOD_Plk_4	76	82	PF00069	0.649
MOD_ProDKin_1	72	78	PF00069	0.716
TRG_DiLeu_BaLyEn_6	25	30	PF01217	0.602
TRG_ENDOCYTIC_2	108	111	PF00928	0.597
TRG_ENDOCYTIC_2	84	87	PF00928	0.595
TRG_ER_diArg_1	176	179	PF00400	0.638
TRG_ER_diArg_1	31	34	PF00400	0.641
TRG_ER_diArg_1	8	11	PF00400	0.708
TRG_NES_CRM1_1	51	62	PF08389	0.665