CAP_C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HNV6_LEIBR

TriTrypDb:

LbrM.35.1090 , LBRM2903_350016700

Length:

193

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 14

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HNV6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNV6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	69	71	PF00675	0.508
CLV_NRD_NRD_1	94	96	PF00675	0.465
CLV_PCSK_SKI1_1	61	65	PF00082	0.469
CLV_PCSK_SKI1_1	76	80	PF00082	0.495
CLV_PCSK_SKI1_1	95	99	PF00082	0.405
DEG_APCC_DBOX_1	33	41	PF00400	0.613
DEG_APCC_DBOX_1	60	68	PF00400	0.477
DOC_CYCLIN_RxL_1	58	68	PF00134	0.472
DOC_MAPK_gen_1	70	81	PF00069	0.513
DOC_MAPK_MEF2A_6	74	83	PF00069	0.517
DOC_MAPK_NFAT4_5	76	84	PF00069	0.517
DOC_PP1_RVXF_1	78	84	PF00149	0.497
DOC_SPAK_OSR1_1	143	147	PF12202	0.493
DOC_USP7_UBL2_3	188	192	PF12436	0.652
LIG_14-3-3_CanoR_1	16	21	PF00244	0.725
LIG_Actin_WH2_2	3	18	PF00022	0.619
LIG_Actin_WH2_2	84	101	PF00022	0.540
LIG_BIR_II_1	1	5	PF00653	0.548
LIG_FHA_1	106	112	PF00498	0.415
LIG_FHA_1	113	119	PF00498	0.494
LIG_FHA_1	121	127	PF00498	0.448
LIG_FHA_1	152	158	PF00498	0.450
LIG_FHA_2	53	59	PF00498	0.469
LIG_FHA_2	83	89	PF00498	0.506
LIG_Integrin_isoDGR_2	93	95	PF01839	0.477
LIG_LIR_Gen_1	154	164	PF02991	0.352
LIG_LIR_Nem_3	135	141	PF02991	0.441
LIG_LIR_Nem_3	154	159	PF02991	0.329
LIG_NRBOX	62	68	PF00104	0.532
LIG_Pex14_2	181	185	PF04695	0.467
LIG_Pex14_2	83	87	PF04695	0.439
LIG_PTB_Apo_2	179	186	PF02174	0.476
LIG_SH2_STAT5	165	168	PF00017	0.373
LIG_SUMO_SIM_par_1	121	129	PF11976	0.581
LIG_SUMO_SIM_par_1	62	68	PF11976	0.582
LIG_TRAF2_1	55	58	PF00917	0.439
LIG_UBA3_1	180	188	PF00899	0.480
LIG_UBA3_1	63	71	PF00899	0.476
MOD_CK2_1	52	58	PF00069	0.484
MOD_CK2_1	82	88	PF00069	0.532
MOD_CK2_1	99	105	PF00069	0.630
MOD_Cter_Amidation	93	96	PF01082	0.460
MOD_GlcNHglycan	101	104	PF01048	0.591
MOD_GlcNHglycan	147	150	PF01048	0.599
MOD_GSK3_1	101	108	PF00069	0.559
MOD_GSK3_1	120	127	PF00069	0.479
MOD_GSK3_1	151	158	PF00069	0.474
MOD_GSK3_1	39	46	PF00069	0.392
MOD_N-GLC_1	8	13	PF02516	0.573
MOD_NEK2_1	187	192	PF00069	0.502
MOD_NEK2_1	8	13	PF00069	0.593
MOD_NEK2_1	98	103	PF00069	0.490
MOD_PIKK_1	43	49	PF00454	0.400
MOD_PIKK_1	8	14	PF00454	0.612
MOD_PK_1	114	120	PF00069	0.543
MOD_PKB_1	14	22	PF00069	0.620
MOD_Plk_1	120	126	PF00069	0.455
MOD_Plk_2-3	52	58	PF00069	0.567
MOD_SUMO_for_1	149	152	PF00179	0.488
MOD_SUMO_for_1	53	56	PF00179	0.494
MOD_SUMO_rev_2	50	55	PF00179	0.548
TRG_DiLeu_BaEn_2	139	145	PF01217	0.456
TRG_DiLeu_BaEn_2	151	157	PF01217	0.476
TRG_NES_CRM1_1	136	147	PF08389	0.460
TRG_Pf-PMV_PEXEL_1	61	65	PF00026	0.460

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IHX7	Leptomonas seymouri	86%	99%
A0A0S4JAX8	Bodo saltans	27%	87%
A0A1X0P947	Trypanosomatidae	64%	95%
A0A3S5H817	Leishmania donovani	90%	85%
A0A422NTY7	Trypanosoma rangeli	66%	94%
A4ICN7	Leishmania infantum	90%	85%
E9ASL7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	97%
Q4Q1X9	Leishmania major	91%	100%
V5B9W8	Trypanosoma cruzi	64%	95%