Guanylate cyclase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Guanylate cyclase

Gene product:

mitogen-activated protein kinase-like protein

Species:

Leishmania braziliensis

UniProt:

A4HNV1_LEIBR

TriTrypDb:

LbrM.35.1030 , LBRM2903_350016000

Length:

1551

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

Expansion

Sequence features

A4HNV1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006163	purine nucleotide metabolic process	5	7
GO:0006164	purine nucleotide biosynthetic process	6	7
GO:0006171	cAMP biosynthetic process	8	7
GO:0006182	cGMP biosynthetic process	8	7
GO:0006468	protein phosphorylation	5	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006753	nucleoside phosphate metabolic process	4	7
GO:0006793	phosphorus metabolic process	3	7
GO:0006796	phosphate-containing compound metabolic process	4	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009058	biosynthetic process	2	7
GO:0009117	nucleotide metabolic process	5	7
GO:0009150	purine ribonucleotide metabolic process	6	7
GO:0009152	purine ribonucleotide biosynthetic process	7	7
GO:0009165	nucleotide biosynthetic process	6	7
GO:0009187	cyclic nucleotide metabolic process	6	7
GO:0009190	cyclic nucleotide biosynthetic process	7	7
GO:0009259	ribonucleotide metabolic process	5	7
GO:0009260	ribonucleotide biosynthetic process	6	7
GO:0009987	cellular process	1	7
GO:0016310	phosphorylation	5	7
GO:0018130	heterocycle biosynthetic process	4	7
GO:0019438	aromatic compound biosynthetic process	4	7
GO:0019538	protein metabolic process	3	7
GO:0019637	organophosphate metabolic process	3	7
GO:0019693	ribose phosphate metabolic process	4	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0034654	nucleobase-containing compound biosynthetic process	4	7
GO:0036211	protein modification process	4	7
GO:0043170	macromolecule metabolic process	3	7
GO:0043412	macromolecule modification	4	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044249	cellular biosynthetic process	3	7
GO:0044271	cellular nitrogen compound biosynthetic process	4	7
GO:0044281	small molecule metabolic process	2	7
GO:0046058	cAMP metabolic process	7	7
GO:0046068	cGMP metabolic process	7	7
GO:0046390	ribose phosphate biosynthetic process	5	7
GO:0046483	heterocycle metabolic process	3	7
GO:0052652	cyclic purine nucleotide metabolic process	6	7
GO:0055086	nucleobase-containing small molecule metabolic process	3	7
GO:0071704	organic substance metabolic process	2	7
GO:0072521	purine-containing compound metabolic process	4	7
GO:0072522	purine-containing compound biosynthetic process	5	7
GO:0090407	organophosphate biosynthetic process	4	7
GO:1901135	carbohydrate derivative metabolic process	3	7
GO:1901137	carbohydrate derivative biosynthetic process	4	7
GO:1901293	nucleoside phosphate biosynthetic process	5	7
GO:1901360	organic cyclic compound metabolic process	3	7
GO:1901362	organic cyclic compound biosynthetic process	4	7
GO:1901564	organonitrogen compound metabolic process	3	7
GO:1901566	organonitrogen compound biosynthetic process	4	7
GO:1901576	organic substance biosynthetic process	3	7
GO:0007165	signal transduction	2	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0065007	biological regulation	1	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003824	catalytic activity	1	7
GO:0004672	protein kinase activity	3	7
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0016301	kinase activity	4	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	7
GO:0017076	purine nucleotide binding	4	7
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7
GO:0032555	purine ribonucleotide binding	4	7
GO:0032559	adenyl ribonucleotide binding	5	7
GO:0035639	purine ribonucleoside triphosphate binding	4	7
GO:0036094	small molecule binding	2	7
GO:0043167	ion binding	2	7
GO:0043168	anion binding	3	7
GO:0097159	organic cyclic compound binding	2	7
GO:0097367	carbohydrate derivative binding	2	7
GO:0140096	catalytic activity, acting on a protein	2	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1133	1137	PF00656	0.783
CLV_C14_Caspase3-7	1201	1205	PF00656	0.654
CLV_C14_Caspase3-7	1436	1440	PF00656	0.619
CLV_C14_Caspase3-7	439	443	PF00656	0.261
CLV_C14_Caspase3-7	476	480	PF00656	0.471
CLV_C14_Caspase3-7	765	769	PF00656	0.624
CLV_NRD_NRD_1	1127	1129	PF00675	0.414
CLV_NRD_NRD_1	1386	1388	PF00675	0.346
CLV_NRD_NRD_1	1530	1532	PF00675	0.338
CLV_NRD_NRD_1	194	196	PF00675	0.388
CLV_NRD_NRD_1	3	5	PF00675	0.377
CLV_NRD_NRD_1	555	557	PF00675	0.457
CLV_NRD_NRD_1	695	697	PF00675	0.362
CLV_NRD_NRD_1	953	955	PF00675	0.500
CLV_NRD_NRD_1	962	964	PF00675	0.393
CLV_NRD_NRD_1	971	973	PF00675	0.292
CLV_NRD_NRD_1	989	991	PF00675	0.426
CLV_NRD_NRD_1	99	101	PF00675	0.518
CLV_PCSK_FUR_1	553	557	PF00082	0.444
CLV_PCSK_KEX2_1	1530	1532	PF00082	0.338
CLV_PCSK_KEX2_1	1539	1541	PF00082	0.394
CLV_PCSK_KEX2_1	194	196	PF00082	0.388
CLV_PCSK_KEX2_1	3	5	PF00082	0.377
CLV_PCSK_KEX2_1	394	396	PF00082	0.469
CLV_PCSK_KEX2_1	454	456	PF00082	0.479
CLV_PCSK_KEX2_1	509	511	PF00082	0.489
CLV_PCSK_KEX2_1	539	541	PF00082	0.498
CLV_PCSK_KEX2_1	555	557	PF00082	0.413
CLV_PCSK_KEX2_1	689	691	PF00082	0.346
CLV_PCSK_KEX2_1	695	697	PF00082	0.345
CLV_PCSK_KEX2_1	953	955	PF00082	0.500
CLV_PCSK_KEX2_1	962	964	PF00082	0.393
CLV_PCSK_KEX2_1	971	973	PF00082	0.292
CLV_PCSK_KEX2_1	989	991	PF00082	0.420
CLV_PCSK_KEX2_1	99	101	PF00082	0.488
CLV_PCSK_PC1ET2_1	1539	1541	PF00082	0.238
CLV_PCSK_PC1ET2_1	394	396	PF00082	0.469
CLV_PCSK_PC1ET2_1	454	456	PF00082	0.479
CLV_PCSK_PC1ET2_1	509	511	PF00082	0.489
CLV_PCSK_PC1ET2_1	539	541	PF00082	0.498
CLV_PCSK_PC1ET2_1	689	691	PF00082	0.325
CLV_PCSK_PC7_1	450	456	PF00082	0.479
CLV_PCSK_SKI1_1	1141	1145	PF00082	0.571
CLV_PCSK_SKI1_1	1156	1160	PF00082	0.369
CLV_PCSK_SKI1_1	247	251	PF00082	0.563
CLV_PCSK_SKI1_1	45	49	PF00082	0.338
CLV_PCSK_SKI1_1	504	508	PF00082	0.486
CLV_PCSK_SKI1_1	633	637	PF00082	0.403
CLV_PCSK_SKI1_1	646	650	PF00082	0.375
CLV_PCSK_SKI1_1	669	673	PF00082	0.370
CLV_PCSK_SKI1_1	824	828	PF00082	0.242
CLV_PCSK_SKI1_1	934	938	PF00082	0.374
CLV_Separin_Metazoa	950	954	PF03568	0.505
DEG_APCC_DBOX_1	1079	1087	PF00400	0.716
DEG_APCC_DBOX_1	193	201	PF00400	0.609
DEG_APCC_DBOX_1	35	43	PF00400	0.586
DEG_Kelch_Keap1_1	85	90	PF01344	0.571
DEG_MDM2_SWIB_1	298	306	PF02201	0.347
DEG_Nend_Nbox_1	1	3	PF02207	0.553
DEG_SCF_FBW7_1	1443	1450	PF00400	0.619
DEG_SPOP_SBC_1	484	488	PF00917	0.383
DEG_SPOP_SBC_1	93	97	PF00917	0.620
DOC_MAPK_gen_1	1147	1154	PF00069	0.546
DOC_MAPK_gen_1	1387	1395	PF00069	0.546
DOC_MAPK_gen_1	1435	1443	PF00069	0.438
DOC_MAPK_gen_1	199	208	PF00069	0.634
DOC_MAPK_gen_1	34	42	PF00069	0.589
DOC_MAPK_gen_1	539	547	PF00069	0.278
DOC_MAPK_gen_1	749	757	PF00069	0.564
DOC_MAPK_HePTP_8	200	212	PF00069	0.619
DOC_MAPK_MEF2A_6	1147	1154	PF00069	0.546
DOC_MAPK_MEF2A_6	201	210	PF00069	0.619
DOC_MAPK_MEF2A_6	331	339	PF00069	0.257
DOC_MAPK_MEF2A_6	34	42	PF00069	0.617
DOC_MAPK_MEF2A_6	751	759	PF00069	0.573
DOC_MAPK_NFAT4_5	1147	1155	PF00069	0.547
DOC_PP2B_LxvP_1	294	297	PF13499	0.421
DOC_PP2B_LxvP_1	720	723	PF13499	0.524
DOC_PP4_FxxP_1	1449	1452	PF00568	0.546
DOC_PP4_FxxP_1	807	810	PF00568	0.569
DOC_PP4_FxxP_1	81	84	PF00568	0.604
DOC_USP7_MATH_1	1101	1105	PF00917	0.584
DOC_USP7_MATH_1	1176	1180	PF00917	0.672
DOC_USP7_MATH_1	136	140	PF00917	0.741
DOC_USP7_MATH_1	147	151	PF00917	0.577
DOC_USP7_MATH_1	152	156	PF00917	0.525
DOC_USP7_MATH_1	188	192	PF00917	0.567
DOC_USP7_MATH_1	343	347	PF00917	0.242
DOC_USP7_MATH_1	393	397	PF00917	0.270
DOC_USP7_MATH_1	484	488	PF00917	0.383
DOC_USP7_MATH_1	766	770	PF00917	0.637
DOC_USP7_MATH_1	93	97	PF00917	0.731
DOC_USP7_UBL2_3	934	938	PF12436	0.574
DOC_WW_Pin1_4	1113	1118	PF00397	0.747
DOC_WW_Pin1_4	1169	1174	PF00397	0.809
DOC_WW_Pin1_4	1252	1257	PF00397	0.661
DOC_WW_Pin1_4	126	131	PF00397	0.771
DOC_WW_Pin1_4	1443	1448	PF00397	0.619
DOC_WW_Pin1_4	1505	1510	PF00397	0.460
DOC_WW_Pin1_4	280	285	PF00397	0.317
DOC_WW_Pin1_4	924	929	PF00397	0.658
LIG_14-3-3_CanoR_1	1007	1014	PF00244	0.602
LIG_14-3-3_CanoR_1	1022	1028	PF00244	0.667
LIG_14-3-3_CanoR_1	1037	1045	PF00244	0.509
LIG_14-3-3_CanoR_1	1149	1155	PF00244	0.609
LIG_14-3-3_CanoR_1	1281	1286	PF00244	0.632
LIG_14-3-3_CanoR_1	1448	1452	PF00244	0.531
LIG_14-3-3_CanoR_1	1501	1505	PF00244	0.619
LIG_14-3-3_CanoR_1	1540	1549	PF00244	0.438
LIG_14-3-3_CanoR_1	163	171	PF00244	0.568
LIG_14-3-3_CanoR_1	423	432	PF00244	0.329
LIG_14-3-3_CanoR_1	45	50	PF00244	0.602
LIG_14-3-3_CanoR_1	619	627	PF00244	0.533
LIG_14-3-3_CanoR_1	646	654	PF00244	0.525
LIG_14-3-3_CanoR_1	749	757	PF00244	0.564
LIG_14-3-3_CanoR_1	94	102	PF00244	0.806
LIG_14-3-3_CanoR_1	993	999	PF00244	0.514
LIG_Actin_WH2_2	1147	1162	PF00022	0.558
LIG_AP2alpha_2	533	535	PF02296	0.267
LIG_APCC_ABBA_1	512	517	PF00400	0.259
LIG_APCC_ABBA_1	900	905	PF00400	0.560
LIG_BRCT_BRCA1_1	1045	1049	PF00533	0.584
LIG_BRCT_BRCA1_1	1053	1057	PF00533	0.537
LIG_BRCT_BRCA1_1	154	158	PF00533	0.564
LIG_CaM_NSCaTE_8	302	309	PF13499	0.240
LIG_Clathr_ClatBox_1	1394	1398	PF01394	0.438
LIG_deltaCOP1_diTrp_1	442	448	PF00928	0.471
LIG_EH1_1	912	920	PF00400	0.577
LIG_eIF4E_1	1389	1395	PF01652	0.546
LIG_eIF4E_1	382	388	PF01652	0.269
LIG_eIF4E_1	489	495	PF01652	0.349
LIG_FHA_1	1039	1045	PF00498	0.591
LIG_FHA_1	1114	1120	PF00498	0.602
LIG_FHA_1	120	126	PF00498	0.650
LIG_FHA_1	1291	1297	PF00498	0.626
LIG_FHA_1	13	19	PF00498	0.707
LIG_FHA_1	1310	1316	PF00498	0.404
LIG_FHA_1	1420	1426	PF00498	0.546
LIG_FHA_1	1541	1547	PF00498	0.438
LIG_FHA_1	252	258	PF00498	0.264
LIG_FHA_1	266	272	PF00498	0.223
LIG_FHA_1	285	291	PF00498	0.344
LIG_FHA_1	312	318	PF00498	0.355
LIG_FHA_1	417	423	PF00498	0.419
LIG_FHA_1	520	526	PF00498	0.349
LIG_FHA_1	536	542	PF00498	0.383
LIG_FHA_1	561	567	PF00498	0.399
LIG_FHA_1	732	738	PF00498	0.705
LIG_FHA_1	751	757	PF00498	0.549
LIG_FHA_1	848	854	PF00498	0.581
LIG_FHA_1	881	887	PF00498	0.625
LIG_FHA_2	1027	1033	PF00498	0.696
LIG_FHA_2	1133	1139	PF00498	0.626
LIG_FHA_2	1272	1278	PF00498	0.552
LIG_FHA_2	1517	1523	PF00498	0.462
LIG_FHA_2	1540	1546	PF00498	0.546
LIG_FHA_2	604	610	PF00498	0.277
LIG_FHA_2	647	653	PF00498	0.566
LIG_FHA_2	846	852	PF00498	0.583
LIG_FXI_DFP_1	367	371	PF00024	0.493
LIG_GBD_Chelix_1	212	220	PF00786	0.261
LIG_IRF3_LxIS_1	1305	1310	PF10401	0.483
LIG_IRF3_LxIS_1	571	576	PF10401	0.241
LIG_LIR_Apic_2	1446	1452	PF02991	0.546
LIG_LIR_Apic_2	805	810	PF02991	0.572
LIG_LIR_Gen_1	1304	1311	PF02991	0.619
LIG_LIR_Gen_1	316	326	PF02991	0.438
LIG_LIR_Gen_1	442	452	PF02991	0.454
LIG_LIR_Gen_1	542	552	PF02991	0.349
LIG_LIR_Gen_1	559	569	PF02991	0.359
LIG_LIR_Gen_1	657	665	PF02991	0.564
LIG_LIR_Gen_1	795	803	PF02991	0.553
LIG_LIR_LC3C_4	752	757	PF02991	0.637
LIG_LIR_Nem_3	1046	1052	PF02991	0.641
LIG_LIR_Nem_3	1094	1100	PF02991	0.616
LIG_LIR_Nem_3	1301	1305	PF02991	0.546
LIG_LIR_Nem_3	1356	1362	PF02991	0.546
LIG_LIR_Nem_3	316	321	PF02991	0.272
LIG_LIR_Nem_3	442	448	PF02991	0.455
LIG_LIR_Nem_3	458	463	PF02991	0.302
LIG_LIR_Nem_3	542	547	PF02991	0.348
LIG_LIR_Nem_3	559	564	PF02991	0.359
LIG_LIR_Nem_3	657	661	PF02991	0.563
LIG_LIR_Nem_3	795	799	PF02991	0.549
LIG_LIR_Nem_3	935	940	PF02991	0.574
LIG_MAD2	6	14	PF02301	0.587
LIG_NRBOX	1545	1551	PF00104	0.727
LIG_NRBOX	207	213	PF00104	0.513
LIG_PCNA_yPIPBox_3	345	354	PF02747	0.252
LIG_PCNA_yPIPBox_3	423	432	PF02747	0.482
LIG_Pex14_1	303	307	PF04695	0.240
LIG_Pex14_1	444	448	PF04695	0.407
LIG_Pex14_2	298	302	PF04695	0.347
LIG_Pex14_2	803	807	PF04695	0.574
LIG_PTB_Apo_2	227	234	PF02174	0.355
LIG_PTB_Apo_2	652	659	PF02174	0.613
LIG_PTB_Phospho_1	227	233	PF10480	0.356
LIG_SH2_CRK	382	386	PF00017	0.351
LIG_SH2_CRK	569	573	PF00017	0.349
LIG_SH2_NCK_1	1485	1489	PF00017	0.619
LIG_SH2_PTP2	318	321	PF00017	0.262
LIG_SH2_SRC	1184	1187	PF00017	0.624
LIG_SH2_STAP1	1184	1188	PF00017	0.626
LIG_SH2_STAP1	1349	1353	PF00017	0.546
LIG_SH2_STAP1	1389	1393	PF00017	0.546
LIG_SH2_STAP1	307	311	PF00017	0.268
LIG_SH2_STAP1	400	404	PF00017	0.302
LIG_SH2_STAT3	1399	1402	PF00017	0.546
LIG_SH2_STAT3	903	906	PF00017	0.452
LIG_SH2_STAT3	988	991	PF00017	0.620
LIG_SH2_STAT5	1306	1309	PF00017	0.546
LIG_SH2_STAT5	1399	1402	PF00017	0.546
LIG_SH2_STAT5	233	236	PF00017	0.370
LIG_SH2_STAT5	241	244	PF00017	0.337
LIG_SH2_STAT5	295	298	PF00017	0.420
LIG_SH2_STAT5	30	33	PF00017	0.592
LIG_SH2_STAT5	318	321	PF00017	0.442
LIG_SH2_STAT5	402	405	PF00017	0.376
LIG_SH2_STAT5	460	463	PF00017	0.283
LIG_SH2_STAT5	544	547	PF00017	0.395
LIG_SH2_STAT5	724	727	PF00017	0.528
LIG_SH2_STAT5	844	847	PF00017	0.546
LIG_SH3_1	963	969	PF00018	0.647
LIG_SH3_2	966	971	PF14604	0.720
LIG_SH3_3	1158	1164	PF00018	0.655
LIG_SH3_3	1172	1178	PF00018	0.785
LIG_SH3_3	1208	1214	PF00018	0.627
LIG_SH3_3	1511	1517	PF00018	0.546
LIG_SH3_3	4	10	PF00018	0.739
LIG_SH3_3	64	70	PF00018	0.657
LIG_SH3_3	667	673	PF00018	0.567
LIG_SH3_3	713	719	PF00018	0.665
LIG_SH3_3	963	969	PF00018	0.644
LIG_SUMO_SIM_anti_2	1542	1551	PF11976	0.601
LIG_SUMO_SIM_anti_2	430	439	PF11976	0.464
LIG_SUMO_SIM_anti_2	752	758	PF11976	0.639
LIG_SUMO_SIM_anti_2	768	774	PF11976	0.453
LIG_SUMO_SIM_anti_2	946	953	PF11976	0.483
LIG_SUMO_SIM_par_1	1142	1148	PF11976	0.681
LIG_SUMO_SIM_par_1	1223	1229	PF11976	0.569
LIG_SUMO_SIM_par_1	1281	1286	PF11976	0.548
LIG_SUMO_SIM_par_1	1542	1551	PF11976	0.601
LIG_SUMO_SIM_par_1	571	576	PF11976	0.241
LIG_SUMO_SIM_par_1	752	758	PF11976	0.566
LIG_SUMO_SIM_par_1	789	795	PF11976	0.638
LIG_TRAF2_1	1105	1108	PF00917	0.579
LIG_TRAF2_1	1542	1545	PF00917	0.546
LIG_TRFH_1	382	386	PF08558	0.301
LIG_WRC_WIRS_1	1465	1470	PF05994	0.411
LIG_WRC_WIRS_1	561	566	PF05994	0.431
LIG_WRC_WIRS_1	800	805	PF05994	0.441
MOD_CDK_SPK_2	1443	1448	PF00069	0.513
MOD_CK1_1	1112	1118	PF00069	0.736
MOD_CK1_1	1168	1174	PF00069	0.646
MOD_CK1_1	1179	1185	PF00069	0.607
MOD_CK1_1	1192	1198	PF00069	0.682
MOD_CK1_1	12	18	PF00069	0.606
MOD_CK1_1	1269	1275	PF00069	0.452
MOD_CK1_1	134	140	PF00069	0.669
MOD_CK1_1	1419	1425	PF00069	0.411
MOD_CK1_1	1503	1509	PF00069	0.513
MOD_CK1_1	161	167	PF00069	0.597
MOD_CK1_1	325	331	PF00069	0.444
MOD_CK1_1	465	471	PF00069	0.409
MOD_CK1_1	618	624	PF00069	0.559
MOD_CK1_1	63	69	PF00069	0.668
MOD_CK1_1	802	808	PF00069	0.448
MOD_CK1_1	85	91	PF00069	0.537
MOD_CK1_1	868	874	PF00069	0.452
MOD_CK1_1	921	927	PF00069	0.316
MOD_CK2_1	1026	1032	PF00069	0.549
MOD_CK2_1	1056	1062	PF00069	0.533
MOD_CK2_1	1101	1107	PF00069	0.442
MOD_CK2_1	1132	1138	PF00069	0.538
MOD_CK2_1	1271	1277	PF00069	0.429
MOD_CK2_1	1298	1304	PF00069	0.513
MOD_CK2_1	136	142	PF00069	0.472
MOD_CK2_1	1447	1453	PF00069	0.411
MOD_CK2_1	1539	1545	PF00069	0.411
MOD_CK2_1	317	323	PF00069	0.292
MOD_CK2_1	440	446	PF00069	0.419
MOD_CK2_1	48	54	PF00069	0.503
MOD_CK2_1	603	609	PF00069	0.276
MOD_CK2_1	680	686	PF00069	0.379
MOD_CK2_1	706	712	PF00069	0.576
MOD_CK2_1	84	90	PF00069	0.446
MOD_CK2_1	845	851	PF00069	0.464
MOD_CMANNOS	302	305	PF00535	0.515
MOD_Cter_Amidation	1126	1129	PF01082	0.501
MOD_GlcNHglycan	1038	1041	PF01048	0.465
MOD_GlcNHglycan	1045	1048	PF01048	0.480
MOD_GlcNHglycan	1058	1061	PF01048	0.436
MOD_GlcNHglycan	1112	1115	PF01048	0.499
MOD_GlcNHglycan	1131	1135	PF01048	0.671
MOD_GlcNHglycan	1200	1203	PF01048	0.780
MOD_GlcNHglycan	1257	1260	PF01048	0.703
MOD_GlcNHglycan	1268	1271	PF01048	0.569
MOD_GlcNHglycan	1285	1288	PF01048	0.308
MOD_GlcNHglycan	1315	1318	PF01048	0.261
MOD_GlcNHglycan	1449	1452	PF01048	0.411
MOD_GlcNHglycan	1526	1529	PF01048	0.513
MOD_GlcNHglycan	154	157	PF01048	0.437
MOD_GlcNHglycan	160	163	PF01048	0.400
MOD_GlcNHglycan	172	175	PF01048	0.412
MOD_GlcNHglycan	190	193	PF01048	0.471
MOD_GlcNHglycan	307	310	PF01048	0.263
MOD_GlcNHglycan	649	652	PF01048	0.539
MOD_GlcNHglycan	703	706	PF01048	0.494
MOD_GlcNHglycan	785	788	PF01048	0.340
MOD_GlcNHglycan	839	842	PF01048	0.438
MOD_GlcNHglycan	87	90	PF01048	0.552
MOD_GlcNHglycan	915	918	PF01048	0.307
MOD_GlcNHglycan	96	99	PF01048	0.695
MOD_GlcNHglycan	985	988	PF01048	0.447
MOD_GSK3_1	1022	1029	PF00069	0.646
MOD_GSK3_1	1109	1116	PF00069	0.712
MOD_GSK3_1	1130	1137	PF00069	0.700
MOD_GSK3_1	1165	1172	PF00069	0.682
MOD_GSK3_1	1248	1255	PF00069	0.745
MOD_GSK3_1	1307	1314	PF00069	0.509
MOD_GSK3_1	1415	1422	PF00069	0.485
MOD_GSK3_1	1429	1436	PF00069	0.309
MOD_GSK3_1	1439	1446	PF00069	0.411
MOD_GSK3_1	1464	1471	PF00069	0.411
MOD_GSK3_1	280	287	PF00069	0.494
MOD_GSK3_1	301	308	PF00069	0.431
MOD_GSK3_1	313	320	PF00069	0.396
MOD_GSK3_1	322	329	PF00069	0.510
MOD_GSK3_1	402	409	PF00069	0.357
MOD_GSK3_1	436	443	PF00069	0.477
MOD_GSK3_1	461	468	PF00069	0.429
MOD_GSK3_1	490	497	PF00069	0.606
MOD_GSK3_1	519	526	PF00069	0.384
MOD_GSK3_1	56	63	PF00069	0.539
MOD_GSK3_1	615	622	PF00069	0.459
MOD_GSK3_1	876	883	PF00069	0.369
MOD_LATS_1	558	564	PF00433	0.270
MOD_N-GLC_1	152	157	PF02516	0.442
MOD_N-GLC_1	250	255	PF02516	0.441
MOD_N-GLC_1	285	290	PF02516	0.339
MOD_N-GLC_1	344	349	PF02516	0.310
MOD_N-GLC_1	358	363	PF02516	0.415
MOD_N-GLC_1	465	470	PF02516	0.315
MOD_N-GLC_1	490	495	PF02516	0.412
MOD_N-GLC_1	520	525	PF02516	0.301
MOD_N-GLC_1	680	685	PF02516	0.337
MOD_N-GLC_1	731	736	PF02516	0.393
MOD_N-GLC_2	1088	1090	PF02516	0.359
MOD_NEK2_1	1023	1028	PF00069	0.688
MOD_NEK2_1	1038	1043	PF00069	0.361
MOD_NEK2_1	1145	1150	PF00069	0.431
MOD_NEK2_1	1290	1295	PF00069	0.443
MOD_NEK2_1	1433	1438	PF00069	0.411
MOD_NEK2_1	1468	1473	PF00069	0.411
MOD_NEK2_1	158	163	PF00069	0.597
MOD_NEK2_1	2	7	PF00069	0.548
MOD_NEK2_1	250	255	PF00069	0.441
MOD_NEK2_1	274	279	PF00069	0.612
MOD_NEK2_1	335	340	PF00069	0.421
MOD_NEK2_1	358	363	PF00069	0.358
MOD_NEK2_1	370	375	PF00069	0.376
MOD_NEK2_1	462	467	PF00069	0.439
MOD_NEK2_1	519	524	PF00069	0.366
MOD_NEK2_1	535	540	PF00069	0.216
MOD_NEK2_1	573	578	PF00069	0.516
MOD_NEK2_1	58	63	PF00069	0.517
MOD_NEK2_1	747	752	PF00069	0.340
MOD_NEK2_1	755	760	PF00069	0.449
MOD_NEK2_1	776	781	PF00069	0.457
MOD_NEK2_1	830	835	PF00069	0.399
MOD_NEK2_1	859	864	PF00069	0.545
MOD_NEK2_1	876	881	PF00069	0.375
MOD_NEK2_1	932	937	PF00069	0.414
MOD_NEK2_1	983	988	PF00069	0.497
MOD_OFUCOSY	132	138	PF10250	0.619
MOD_PIKK_1	1291	1297	PF00454	0.513
MOD_PIKK_1	1336	1342	PF00454	0.383
MOD_PIKK_1	147	153	PF00454	0.596
MOD_PIKK_1	358	364	PF00454	0.331
MOD_PIKK_1	402	408	PF00454	0.299
MOD_PIKK_1	423	429	PF00454	0.345
MOD_PIKK_1	918	924	PF00454	0.311
MOD_PK_1	1281	1287	PF00069	0.531
MOD_PKA_1	1539	1545	PF00069	0.513
MOD_PKA_1	689	695	PF00069	0.389
MOD_PKA_2	1006	1012	PF00069	0.375
MOD_PKA_2	1036	1042	PF00069	0.404
MOD_PKA_2	1291	1297	PF00069	0.411
MOD_PKA_2	1298	1304	PF00069	0.411
MOD_PKA_2	1447	1453	PF00069	0.411
MOD_PKA_2	1500	1506	PF00069	0.513
MOD_PKA_2	1539	1545	PF00069	0.411
MOD_PKA_2	2	8	PF00069	0.457
MOD_PKA_2	618	624	PF00069	0.307
MOD_PKA_2	689	695	PF00069	0.487
MOD_PKA_2	93	99	PF00069	0.769
MOD_Plk_1	1031	1037	PF00069	0.434
MOD_Plk_1	250	256	PF00069	0.442
MOD_Plk_1	322	328	PF00069	0.284
MOD_Plk_1	344	350	PF00069	0.347
MOD_Plk_1	358	364	PF00069	0.467
MOD_Plk_1	406	412	PF00069	0.286
MOD_Plk_1	490	496	PF00069	0.446
MOD_Plk_1	520	526	PF00069	0.383
MOD_Plk_1	573	579	PF00069	0.516
MOD_Plk_1	680	686	PF00069	0.341
MOD_Plk_1	737	743	PF00069	0.381
MOD_Plk_4	1115	1121	PF00069	0.573
MOD_Plk_4	1370	1376	PF00069	0.513
MOD_Plk_4	1401	1407	PF00069	0.513
MOD_Plk_4	1545	1551	PF00069	0.563
MOD_Plk_4	251	257	PF00069	0.539
MOD_Plk_4	313	319	PF00069	0.532
MOD_Plk_4	322	328	PF00069	0.434
MOD_Plk_4	406	412	PF00069	0.369
MOD_Plk_4	440	446	PF00069	0.440
MOD_Plk_4	465	471	PF00069	0.485
MOD_Plk_4	520	526	PF00069	0.303
MOD_Plk_4	560	566	PF00069	0.416
MOD_Plk_4	594	600	PF00069	0.424
MOD_Plk_4	672	678	PF00069	0.469
MOD_Plk_4	750	756	PF00069	0.434
MOD_Plk_4	776	782	PF00069	0.455
MOD_Plk_4	859	865	PF00069	0.544
MOD_Plk_4	876	882	PF00069	0.422
MOD_Plk_4	921	927	PF00069	0.486
MOD_Plk_4	932	938	PF00069	0.437
MOD_ProDKin_1	1113	1119	PF00069	0.691
MOD_ProDKin_1	1169	1175	PF00069	0.781
MOD_ProDKin_1	1252	1258	PF00069	0.574
MOD_ProDKin_1	126	132	PF00069	0.727
MOD_ProDKin_1	1443	1449	PF00069	0.513
MOD_ProDKin_1	1505	1511	PF00069	0.290
MOD_ProDKin_1	280	286	PF00069	0.369
MOD_ProDKin_1	924	930	PF00069	0.565
MOD_SUMO_for_1	1410	1413	PF00179	0.513
MOD_SUMO_rev_2	1104	1113	PF00179	0.473
MOD_SUMO_rev_2	1404	1412	PF00179	0.411
MOD_SUMO_rev_2	51	58	PF00179	0.495
TRG_DiLeu_BaEn_1	1545	1550	PF01217	0.668
TRG_DiLeu_BaEn_1	267	272	PF01217	0.294
TRG_DiLeu_BaEn_1	738	743	PF01217	0.531
TRG_DiLeu_BaEn_3	1138	1144	PF01217	0.489
TRG_DiLeu_BaLyEn_6	1161	1166	PF01217	0.485
TRG_DiLeu_LyEn_5	738	743	PF01217	0.531
TRG_ENDOCYTIC_2	1306	1309	PF00928	0.411
TRG_ENDOCYTIC_2	233	236	PF00928	0.424
TRG_ENDOCYTIC_2	295	298	PF00928	0.467
TRG_ENDOCYTIC_2	318	321	PF00928	0.546
TRG_ENDOCYTIC_2	382	385	PF00928	0.490
TRG_ENDOCYTIC_2	400	403	PF00928	0.360
TRG_ENDOCYTIC_2	460	463	PF00928	0.388
TRG_ENDOCYTIC_2	544	547	PF00928	0.428
TRG_ER_diArg_1	1529	1531	PF00400	0.387
TRG_ER_diArg_1	193	195	PF00400	0.485
TRG_ER_diArg_1	2	4	PF00400	0.441
TRG_ER_diArg_1	554	556	PF00400	0.292
TRG_ER_diArg_1	952	954	PF00400	0.591
TRG_ER_diArg_1	970	972	PF00400	0.341
TRG_ER_diArg_1	988	990	PF00400	0.517
TRG_NES_CRM1_1	1081	1094	PF08389	0.374
TRG_Pf-PMV_PEXEL_1	100	105	PF00026	0.532
TRG_Pf-PMV_PEXEL_1	1067	1072	PF00026	0.555
TRG_Pf-PMV_PEXEL_1	1435	1439	PF00026	0.513

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P883	Leptomonas seymouri	48%	99%
A0A3S7XAH3	Leishmania donovani	63%	99%
A4ICP3	Leishmania infantum	63%	99%
E9ASL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	64%	99%
Q4Q1Y5	Leishmania major	63%	100%