Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HNT9_LEIBR

TriTrypDb:

LbrM.35.0910 , LBRM2903_350014700

Length:

559

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HNT9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNT9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	488	492	PF00656	0.616
CLV_C14_Caspase3-7	518	522	PF00656	0.539
CLV_NRD_NRD_1	263	265	PF00675	0.644
CLV_NRD_NRD_1	343	345	PF00675	0.680
CLV_NRD_NRD_1	411	413	PF00675	0.707
CLV_NRD_NRD_1	469	471	PF00675	0.584
CLV_NRD_NRD_1	475	477	PF00675	0.564
CLV_NRD_NRD_1	528	530	PF00675	0.604
CLV_PCSK_KEX2_1	243	245	PF00082	0.791
CLV_PCSK_KEX2_1	262	264	PF00082	0.646
CLV_PCSK_KEX2_1	343	345	PF00082	0.680
CLV_PCSK_KEX2_1	469	471	PF00082	0.584
CLV_PCSK_KEX2_1	474	476	PF00082	0.566
CLV_PCSK_PC1ET2_1	243	245	PF00082	0.691
CLV_PCSK_PC7_1	470	476	PF00082	0.567
CLV_PCSK_SKI1_1	207	211	PF00082	0.641
CLV_PCSK_SKI1_1	244	248	PF00082	0.592
CLV_PCSK_SKI1_1	349	353	PF00082	0.561
CLV_PCSK_SKI1_1	388	392	PF00082	0.563
CLV_PCSK_SKI1_1	425	429	PF00082	0.652
CLV_PCSK_SKI1_1	434	438	PF00082	0.603
CLV_PCSK_SKI1_1	541	545	PF00082	0.525
DEG_APCC_DBOX_1	211	219	PF00400	0.524
DEG_APCC_DBOX_1	387	395	PF00400	0.635
DEG_Nend_UBRbox_3	1	3	PF02207	0.542
DEG_SPOP_SBC_1	26	30	PF00917	0.562
DOC_CKS1_1	298	303	PF01111	0.558
DOC_CKS1_1	50	55	PF01111	0.731
DOC_CYCLIN_RxL_1	469	481	PF00134	0.571
DOC_CYCLIN_yClb5_NLxxxL_5	1	10	PF00134	0.533
DOC_MAPK_MEF2A_6	3	12	PF00069	0.679
DOC_MAPK_NFAT4_5	3	11	PF00069	0.528
DOC_PP1_RVXF_1	539	546	PF00149	0.540
DOC_PP2B_LxvP_1	477	480	PF13499	0.582
DOC_PP2B_LxvP_1	511	514	PF13499	0.519
DOC_PP2B_LxvP_1	8	11	PF13499	0.531
DOC_PP4_FxxP_1	361	364	PF00568	0.722
DOC_PP4_FxxP_1	429	432	PF00568	0.558
DOC_USP7_MATH_1	137	141	PF00917	0.393
DOC_USP7_MATH_1	245	249	PF00917	0.694
DOC_USP7_MATH_1	331	335	PF00917	0.678
DOC_USP7_MATH_1	351	355	PF00917	0.747
DOC_USP7_MATH_1	372	376	PF00917	0.555
DOC_USP7_MATH_1	397	401	PF00917	0.785
DOC_USP7_MATH_1	484	488	PF00917	0.600
DOC_USP7_MATH_1	516	520	PF00917	0.623
DOC_USP7_MATH_1	83	87	PF00917	0.687
DOC_USP7_MATH_1	90	94	PF00917	0.601
DOC_WW_Pin1_4	170	175	PF00397	0.487
DOC_WW_Pin1_4	283	288	PF00397	0.748
DOC_WW_Pin1_4	297	302	PF00397	0.647
DOC_WW_Pin1_4	37	42	PF00397	0.775
DOC_WW_Pin1_4	478	483	PF00397	0.715
DOC_WW_Pin1_4	49	54	PF00397	0.632
DOC_WW_Pin1_4	69	74	PF00397	0.800
DOC_WW_Pin1_4	79	84	PF00397	0.680
LIG_14-3-3_CanoR_1	14	19	PF00244	0.692
LIG_14-3-3_CanoR_1	244	253	PF00244	0.569
LIG_14-3-3_CanoR_1	262	267	PF00244	0.530
LIG_14-3-3_CanoR_1	293	301	PF00244	0.565
LIG_14-3-3_CanoR_1	332	336	PF00244	0.565
LIG_14-3-3_CanoR_1	349	358	PF00244	0.620
LIG_14-3-3_CanoR_1	398	408	PF00244	0.700
LIG_14-3-3_CanoR_1	425	430	PF00244	0.578
LIG_BIR_III_4	161	165	PF00653	0.463
LIG_BRCT_BRCA1_1	438	442	PF00533	0.525
LIG_CtBP_PxDLS_1	316	320	PF00389	0.553
LIG_CtBP_PxDLS_1	78	82	PF00389	0.664
LIG_FHA_1	181	187	PF00498	0.562
LIG_FHA_1	350	356	PF00498	0.548
LIG_FHA_1	390	396	PF00498	0.687
LIG_FHA_2	115	121	PF00498	0.535
LIG_FHA_2	125	131	PF00498	0.439
LIG_FHA_2	27	33	PF00498	0.571
LIG_FHA_2	340	346	PF00498	0.692
LIG_LIR_Apic_2	428	432	PF02991	0.561
LIG_LIR_Gen_1	184	191	PF02991	0.554
LIG_LIR_Gen_1	504	514	PF02991	0.602
LIG_LIR_Nem_3	184	190	PF02991	0.558
LIG_LIR_Nem_3	504	509	PF02991	0.642
LIG_MYND_3	76	80	PF01753	0.581
LIG_PCNA_yPIPBox_3	376	388	PF02747	0.514
LIG_Pex14_2	109	113	PF04695	0.530
LIG_Pex14_2	12	16	PF04695	0.685
LIG_SH2_CRK	155	159	PF00017	0.493
LIG_SH2_STAP1	187	191	PF00017	0.550
LIG_SH2_STAT5	299	302	PF00017	0.709
LIG_SH3_1	284	290	PF00018	0.655
LIG_SH3_1	530	536	PF00018	0.540
LIG_SH3_1	57	63	PF00018	0.573
LIG_SH3_2	60	65	PF14604	0.585
LIG_SH3_3	284	290	PF00018	0.655
LIG_SH3_3	295	301	PF00018	0.566
LIG_SH3_3	352	358	PF00018	0.590
LIG_SH3_3	415	421	PF00018	0.562
LIG_SH3_3	47	53	PF00018	0.741
LIG_SH3_3	530	536	PF00018	0.540
LIG_SH3_3	57	63	PF00018	0.628
LIG_SH3_3	72	78	PF00018	0.611
LIG_SH3_3	97	103	PF00018	0.581
LIG_SUMO_SIM_par_1	77	82	PF11976	0.582
LIG_TRAF2_1	146	149	PF00917	0.524
LIG_TRAF2_1	449	452	PF00917	0.602
LIG_WRC_WIRS_1	503	508	PF05994	0.621
LIG_WW_3	431	435	PF00397	0.665
MOD_CDC14_SPxK_1	54	57	PF00782	0.731
MOD_CDK_SPxK_1	51	57	PF00069	0.734
MOD_CK1_1	140	146	PF00069	0.384
MOD_CK1_1	173	179	PF00069	0.639
MOD_CK1_1	182	188	PF00069	0.459
MOD_CK1_1	248	254	PF00069	0.680
MOD_CK1_1	265	271	PF00069	0.636
MOD_CK1_1	272	278	PF00069	0.685
MOD_CK1_1	292	298	PF00069	0.533
MOD_CK1_1	318	324	PF00069	0.773
MOD_CK1_1	325	331	PF00069	0.669
MOD_CK1_1	339	345	PF00069	0.575
MOD_CK1_1	401	407	PF00069	0.782
MOD_CK1_1	42	48	PF00069	0.710
MOD_CK1_1	93	99	PF00069	0.581
MOD_CK2_1	114	120	PF00069	0.535
MOD_CK2_1	124	130	PF00069	0.452
MOD_CK2_1	173	179	PF00069	0.594
MOD_CK2_1	182	188	PF00069	0.451
MOD_CK2_1	339	345	PF00069	0.693
MOD_CK2_1	446	452	PF00069	0.691
MOD_CMANNOS	542	545	PF00535	0.687
MOD_DYRK1A_RPxSP_1	297	301	PF00069	0.560
MOD_GlcNHglycan	122	125	PF01048	0.657
MOD_GlcNHglycan	247	250	PF01048	0.576
MOD_GlcNHglycan	302	305	PF01048	0.798
MOD_GlcNHglycan	333	336	PF01048	0.698
MOD_GlcNHglycan	395	398	PF01048	0.743
MOD_GlcNHglycan	401	404	PF01048	0.719
MOD_GlcNHglycan	442	445	PF01048	0.691
MOD_GlcNHglycan	549	552	PF01048	0.650
MOD_GlcNHglycan	555	558	PF01048	0.712
MOD_GSK3_1	120	127	PF00069	0.512
MOD_GSK3_1	14	21	PF00069	0.731
MOD_GSK3_1	165	172	PF00069	0.538
MOD_GSK3_1	182	189	PF00069	0.527
MOD_GSK3_1	235	242	PF00069	0.569
MOD_GSK3_1	244	251	PF00069	0.645
MOD_GSK3_1	264	271	PF00069	0.738
MOD_GSK3_1	272	279	PF00069	0.624
MOD_GSK3_1	285	292	PF00069	0.600
MOD_GSK3_1	293	300	PF00069	0.653
MOD_GSK3_1	306	313	PF00069	0.614
MOD_GSK3_1	315	322	PF00069	0.655
MOD_GSK3_1	389	396	PF00069	0.585
MOD_GSK3_1	397	404	PF00069	0.714
MOD_GSK3_1	436	443	PF00069	0.664
MOD_GSK3_1	497	504	PF00069	0.609
MOD_GSK3_1	51	58	PF00069	0.616
MOD_GSK3_1	549	556	PF00069	0.584
MOD_GSK3_1	79	86	PF00069	0.687
MOD_LATS_1	291	297	PF00433	0.620
MOD_N-GLC_1	124	129	PF02516	0.482
MOD_NEK2_1	113	118	PF00069	0.547
MOD_NEK2_1	180	185	PF00069	0.609
MOD_NEK2_1	186	191	PF00069	0.467
MOD_NEK2_1	317	322	PF00069	0.681
MOD_NEK2_1	44	49	PF00069	0.712
MOD_NEK2_1	64	69	PF00069	0.700
MOD_PIKK_1	319	325	PF00454	0.553
MOD_PIKK_1	401	407	PF00454	0.626
MOD_PIKK_1	42	48	PF00454	0.670
MOD_PKA_1	262	268	PF00069	0.602
MOD_PKA_2	262	268	PF00069	0.675
MOD_PKA_2	273	279	PF00069	0.601
MOD_PKA_2	292	298	PF00069	0.523
MOD_PKA_2	310	316	PF00069	0.527
MOD_PKA_2	331	337	PF00069	0.691
MOD_PKA_2	397	403	PF00069	0.675
MOD_PKA_2	516	522	PF00069	0.600
MOD_PKB_1	262	270	PF00069	0.558
MOD_Plk_1	325	331	PF00069	0.738
MOD_Plk_1	93	99	PF00069	0.568
MOD_Plk_4	128	134	PF00069	0.579
MOD_Plk_4	173	179	PF00069	0.676
MOD_Plk_4	182	188	PF00069	0.572
MOD_Plk_4	325	331	PF00069	0.667
MOD_Plk_4	389	395	PF00069	0.638
MOD_ProDKin_1	170	176	PF00069	0.485
MOD_ProDKin_1	283	289	PF00069	0.747
MOD_ProDKin_1	297	303	PF00069	0.646
MOD_ProDKin_1	37	43	PF00069	0.769
MOD_ProDKin_1	478	484	PF00069	0.714
MOD_ProDKin_1	49	55	PF00069	0.631
MOD_ProDKin_1	69	75	PF00069	0.792
MOD_ProDKin_1	79	85	PF00069	0.679
TRG_DiLeu_BaEn_1	206	211	PF01217	0.538
TRG_DiLeu_BaEn_1	386	391	PF01217	0.628
TRG_DiLeu_BaLyEn_6	153	158	PF01217	0.373
TRG_ENDOCYTIC_2	155	158	PF00928	0.527
TRG_ENDOCYTIC_2	187	190	PF00928	0.554
TRG_ER_diArg_1	213	216	PF00400	0.603
TRG_ER_diArg_1	262	264	PF00400	0.599
TRG_ER_diArg_1	474	476	PF00400	0.578
TRG_ER_diArg_1	57	60	PF00400	0.576
TRG_Pf-PMV_PEXEL_1	145	149	PF00026	0.440
TRG_Pf-PMV_PEXEL_1	156	161	PF00026	0.480

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IGY6	Leishmania donovani	54%	100%
A4ICQ5	Leishmania infantum	54%	100%
E9ASJ9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	55%	100%
Q4Q1Z7	Leishmania major	55%	100%