Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HNT7_LEIBR

TriTrypDb:

LbrM.35.0890 , LBRM2903_350014400

Length:

346

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A4HNT7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNT7

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	71	75	PF00656	0.553
CLV_NRD_NRD_1	11	13	PF00675	0.726
CLV_NRD_NRD_1	147	149	PF00675	0.326
CLV_NRD_NRD_1	239	241	PF00675	0.569
CLV_NRD_NRD_1	319	321	PF00675	0.752
CLV_NRD_NRD_1	329	331	PF00675	0.621
CLV_PCSK_FUR_1	9	13	PF00082	0.672
CLV_PCSK_KEX2_1	11	13	PF00082	0.728
CLV_PCSK_KEX2_1	147	149	PF00082	0.321
CLV_PCSK_KEX2_1	239	241	PF00082	0.551

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFS7	Leptomonas seymouri	39%	78%
A0A1X0P881	Trypanosomatidae	25%	74%
A0A3Q8IFT7	Leishmania donovani	68%	79%
A0A422NK60	Trypanosoma rangeli	27%	82%
A4ICQ7	Leishmania infantum	68%	79%
D0A2Q4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	80%
E9ASJ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	67%	79%
Q4Q1Z9	Leishmania major	68%	100%
V5BZW6	Trypanosoma cruzi	24%	82%

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