LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HNT7_LEIBR
TriTrypDb:
LbrM.35.0890 , LBRM2903_350014400 *
Length:
346

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

A4HNT7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNT7

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 71 75 PF00656 0.553
CLV_NRD_NRD_1 11 13 PF00675 0.726
CLV_NRD_NRD_1 147 149 PF00675 0.326
CLV_NRD_NRD_1 239 241 PF00675 0.569
CLV_NRD_NRD_1 319 321 PF00675 0.752
CLV_NRD_NRD_1 329 331 PF00675 0.621
CLV_PCSK_FUR_1 9 13 PF00082 0.672
CLV_PCSK_KEX2_1 11 13 PF00082 0.728
CLV_PCSK_KEX2_1 147 149 PF00082 0.321
CLV_PCSK_KEX2_1 239 241 PF00082 0.551
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PFS7 Leptomonas seymouri 39% 78%
A0A1X0P881 Trypanosomatidae 25% 74%
A0A3Q8IFT7 Leishmania donovani 68% 79%
A0A422NK60 Trypanosoma rangeli 27% 82%
A4ICQ7 Leishmania infantum 68% 79%
D0A2Q4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 26% 80%
E9ASJ7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 67% 79%
Q4Q1Z9 Leishmania major 68% 100%
V5BZW6 Trypanosoma cruzi 24% 82%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS