Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HNS9_LEIBR

TriTrypDb:

LbrM.35.0810 , LBRM2903_350013400

Length:

268

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HNS9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNS9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	51	53	PF00675	0.605
CLV_NRD_NRD_1	76	78	PF00675	0.540
CLV_PCSK_KEX2_1	132	134	PF00082	0.590
CLV_PCSK_KEX2_1	51	53	PF00082	0.605
CLV_PCSK_KEX2_1	75	77	PF00082	0.568
CLV_PCSK_PC1ET2_1	132	134	PF00082	0.627
CLV_PCSK_PC1ET2_1	75	77	PF00082	0.613
CLV_PCSK_SKI1_1	163	167	PF00082	0.520
CLV_PCSK_SKI1_1	209	213	PF00082	0.403
CLV_PCSK_SKI1_1	242	246	PF00082	0.544
CLV_PCSK_SKI1_1	27	31	PF00082	0.548
DEG_Nend_UBRbox_1	1	4	PF02207	0.627
DEG_SCF_TRCP1_1	10	16	PF00400	0.474
DOC_MAPK_DCC_7	242	251	PF00069	0.430
DOC_MAPK_MEF2A_6	242	251	PF00069	0.430
DOC_USP7_MATH_1	122	126	PF00917	0.677
DOC_USP7_MATH_1	17	21	PF00917	0.655
DOC_USP7_MATH_1	196	200	PF00917	0.730
DOC_USP7_MATH_1	45	49	PF00917	0.582
DOC_USP7_MATH_1	64	68	PF00917	0.535
DOC_WW_Pin1_4	118	123	PF00397	0.599
DOC_WW_Pin1_4	164	169	PF00397	0.402
DOC_WW_Pin1_4	175	180	PF00397	0.465
LIG_14-3-3_CanoR_1	51	56	PF00244	0.579
LIG_14-3-3_CanoR_1	62	71	PF00244	0.605
LIG_14-3-3_CanoR_1	85	93	PF00244	0.627
LIG_14-3-3_CterR_2	265	268	PF00244	0.449
LIG_FHA_1	135	141	PF00498	0.567
LIG_FHA_1	176	182	PF00498	0.443
LIG_FHA_1	243	249	PF00498	0.440
LIG_FHA_1	90	96	PF00498	0.556
LIG_FHA_2	55	61	PF00498	0.521
LIG_LIR_Nem_3	70	74	PF02991	0.541
LIG_MYND_3	246	250	PF01753	0.486
LIG_PCNA_yPIPBox_3	222	236	PF02747	0.413
LIG_SH2_SRC	108	111	PF00017	0.439
LIG_SH2_STAT5	108	111	PF00017	0.464
LIG_SH3_3	241	247	PF00018	0.465
LIG_SUMO_SIM_par_1	22	28	PF11976	0.540
LIG_SUMO_SIM_par_1	247	252	PF11976	0.325
LIG_SUMO_SIM_par_1	91	96	PF11976	0.545
MOD_CK1_1	13	19	PF00069	0.582
MOD_CK1_1	153	159	PF00069	0.609
MOD_CK1_1	184	190	PF00069	0.598
MOD_CK1_1	200	206	PF00069	0.550
MOD_CK1_1	63	69	PF00069	0.579
MOD_CK2_1	22	28	PF00069	0.664
MOD_CK2_1	54	60	PF00069	0.585
MOD_CK2_1	67	73	PF00069	0.562
MOD_Cter_Amidation	130	133	PF01082	0.578
MOD_GlcNHglycan	10	13	PF01048	0.559
MOD_GlcNHglycan	105	108	PF01048	0.516
MOD_GlcNHglycan	124	127	PF01048	0.574
MOD_GlcNHglycan	19	22	PF01048	0.636
MOD_GlcNHglycan	226	229	PF01048	0.378
MOD_GlcNHglycan	40	43	PF01048	0.754
MOD_GlcNHglycan	45	48	PF01048	0.682
MOD_GlcNHglycan	62	65	PF01048	0.602
MOD_GlcNHglycan	66	69	PF01048	0.573
MOD_GSK3_1	118	125	PF00069	0.568
MOD_GSK3_1	13	20	PF00069	0.642
MOD_GSK3_1	134	141	PF00069	0.531
MOD_GSK3_1	150	157	PF00069	0.412
MOD_GSK3_1	177	184	PF00069	0.618
MOD_GSK3_1	196	203	PF00069	0.594
MOD_GSK3_1	56	63	PF00069	0.621
MOD_GSK3_1	85	92	PF00069	0.531
MOD_N-GLC_1	60	65	PF02516	0.567
MOD_NEK2_1	150	155	PF00069	0.523
MOD_NEK2_1	256	261	PF00069	0.484
MOD_NEK2_1	8	13	PF00069	0.603
MOD_PIKK_1	139	145	PF00454	0.411
MOD_PKA_1	51	57	PF00069	0.593
MOD_PKA_2	51	57	PF00069	0.593
MOD_PKA_2	84	90	PF00069	0.508
MOD_Plk_1	27	33	PF00069	0.499
MOD_Plk_4	177	183	PF00069	0.454
MOD_Plk_4	19	25	PF00069	0.474
MOD_Plk_4	197	203	PF00069	0.536
MOD_Plk_4	45	51	PF00069	0.655
MOD_ProDKin_1	118	124	PF00069	0.606
MOD_ProDKin_1	164	170	PF00069	0.399
MOD_ProDKin_1	175	181	PF00069	0.474
TRG_ER_diArg_1	50	52	PF00400	0.600
TRG_NES_CRM1_1	239	250	PF08389	0.454
TRG_Pf-PMV_PEXEL_1	6	10	PF00026	0.547

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFQ8	Leptomonas seymouri	37%	89%
A0A3S7XAG1	Leishmania donovani	77%	100%
A4ICR5	Leishmania infantum	78%	100%
E9ASI9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%
Q4Q207	Leishmania major	76%	100%