DNAJ protein-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNAJ protein-like protein

Species:

Leishmania braziliensis

UniProt:

A4HNS1_LEIBR

TriTrypDb:

LbrM.35.0730 , LBRM2903_350012600

Length:

260

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HNS1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNS1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	231	233	PF00675	0.411
CLV_PCSK_KEX2_1	231	233	PF00082	0.411
CLV_PCSK_SKI1_1	113	117	PF00082	0.672
CLV_PCSK_SKI1_1	193	197	PF00082	0.411
CLV_PCSK_SKI1_1	216	220	PF00082	0.411
DEG_APCC_DBOX_1	162	170	PF00400	0.460
DEG_SCF_FBW7_1	46	52	PF00400	0.516
DOC_CKS1_1	46	51	PF01111	0.514
DOC_CYCLIN_RxL_1	188	201	PF00134	0.411
DOC_MAPK_gen_1	161	169	PF00069	0.558
DOC_MAPK_gen_1	192	198	PF00069	0.416
DOC_PP4_FxxP_1	68	71	PF00568	0.677
DOC_USP7_MATH_1	180	184	PF00917	0.355
DOC_USP7_MATH_1	242	246	PF00917	0.513
DOC_USP7_MATH_1	25	29	PF00917	0.700
DOC_USP7_MATH_1	76	80	PF00917	0.749
DOC_USP7_UBL2_3	113	117	PF12436	0.662
DOC_USP7_UBL2_3	157	161	PF12436	0.617
DOC_USP7_UBL2_3	188	192	PF12436	0.513
DOC_USP7_UBL2_3	216	220	PF12436	0.411
DOC_WW_Pin1_4	205	210	PF00397	0.261
DOC_WW_Pin1_4	27	32	PF00397	0.562
DOC_WW_Pin1_4	34	39	PF00397	0.625
DOC_WW_Pin1_4	45	50	PF00397	0.640
DOC_WW_Pin1_4	72	77	PF00397	0.700
LIG_APCC_ABBA_1	196	201	PF00400	0.411
LIG_BRCT_BRCA1_1	10	14	PF00533	0.495
LIG_FHA_1	11	17	PF00498	0.625
LIG_FHA_1	46	52	PF00498	0.555
LIG_FHA_1	55	61	PF00498	0.557
LIG_FHA_2	179	185	PF00498	0.411
LIG_FHA_2	206	212	PF00498	0.383
LIG_FHA_2	7	13	PF00498	0.660
LIG_LIR_Apic_2	66	71	PF02991	0.681
LIG_LIR_Apic_2	79	85	PF02991	0.708
LIG_LIR_Nem_3	17	23	PF02991	0.636
LIG_LIR_Nem_3	213	218	PF02991	0.355
LIG_PTB_Apo_2	62	69	PF02174	0.676
LIG_Rb_pABgroove_1	103	111	PF01858	0.782
LIG_SH2_CRK	173	177	PF00017	0.411
LIG_SH2_CRK	82	86	PF00017	0.759
LIG_SH2_NCK_1	120	124	PF00017	0.646
LIG_SH2_STAP1	234	238	PF00017	0.549
LIG_SH2_STAT5	93	96	PF00017	0.695
LIG_SH3_3	43	49	PF00018	0.509
LIG_SH3_4	113	120	PF00018	0.727
LIG_TRAF2_1	182	185	PF00917	0.411
LIG_TRAF2_1	208	211	PF00917	0.383
LIG_UBA3_1	108	116	PF00899	0.672
LIG_UBA3_1	214	220	PF00899	0.411
LIG_WRC_WIRS_1	41	46	PF05994	0.512
MOD_CDK_SPK_2	45	50	PF00069	0.508
MOD_CK1_1	24	30	PF00069	0.612
MOD_CK1_1	245	251	PF00069	0.629
MOD_CK1_1	32	38	PF00069	0.630
MOD_CK1_1	53	59	PF00069	0.755
MOD_CK1_1	8	14	PF00069	0.745
MOD_CK1_1	97	103	PF00069	0.747
MOD_CK2_1	122	128	PF00069	0.735
MOD_CK2_1	178	184	PF00069	0.411
MOD_CK2_1	205	211	PF00069	0.383
MOD_CK2_1	223	229	PF00069	0.378
MOD_Cter_Amidation	133	136	PF01082	0.672
MOD_GlcNHglycan	138	141	PF01048	0.682
MOD_GlcNHglycan	23	26	PF01048	0.675
MOD_GlcNHglycan	244	247	PF01048	0.658
MOD_GlcNHglycan	249	252	PF01048	0.552
MOD_GlcNHglycan	27	30	PF01048	0.678
MOD_GlcNHglycan	31	34	PF01048	0.669
MOD_GlcNHglycan	53	56	PF01048	0.639
MOD_GlcNHglycan	97	100	PF01048	0.683
MOD_GSK3_1	1	8	PF00069	0.699
MOD_GSK3_1	21	28	PF00069	0.626
MOD_GSK3_1	45	52	PF00069	0.572
MOD_GSK3_1	54	61	PF00069	0.733
MOD_GSK3_1	72	79	PF00069	0.653
MOD_N-GLC_1	151	156	PF02516	0.532
MOD_N-GLC_1	205	210	PF02516	0.261
MOD_N-GLC_1	25	30	PF02516	0.681
MOD_N-GLC_1	6	11	PF02516	0.755
MOD_NEK2_1	1	6	PF00069	0.582
MOD_NEK2_1	109	114	PF00069	0.672
MOD_NEK2_1	19	24	PF00069	0.667
MOD_NEK2_1	233	238	PF00069	0.532
MOD_NEK2_1	39	44	PF00069	0.679
MOD_PKA_2	95	101	PF00069	0.530
MOD_Plk_1	234	240	PF00069	0.554
MOD_Plk_2-3	223	229	PF00069	0.411
MOD_Plk_4	122	128	PF00069	0.633
MOD_Plk_4	59	65	PF00069	0.658
MOD_ProDKin_1	205	211	PF00069	0.261
MOD_ProDKin_1	27	33	PF00069	0.562
MOD_ProDKin_1	34	40	PF00069	0.626
MOD_ProDKin_1	45	51	PF00069	0.643
MOD_ProDKin_1	72	78	PF00069	0.702
MOD_SUMO_rev_2	158	162	PF00179	0.543
MOD_SUMO_rev_2	183	190	PF00179	0.513
TRG_DiLeu_BaLyEn_6	162	167	PF01217	0.544
TRG_ENDOCYTIC_2	172	175	PF00928	0.411
TRG_ER_diArg_1	162	165	PF00400	0.554
TRG_ER_diArg_1	231	233	PF00400	0.513
TRG_NLS_MonoExtC_3	191	197	PF00514	0.290
TRG_Pf-PMV_PEXEL_1	231	235	PF00026	0.261

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7W1	Leptomonas seymouri	61%	85%
A0A3Q8IQI1	Leishmania donovani	73%	100%
A4ICS3	Leishmania infantum	73%	100%
E9ASI1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	71%	100%
Q4Q215	Leishmania major	71%	100%