Zinc-finger of a C2HC-type family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

zinc-finger of a C2HC-type, putative

Species:

Leishmania braziliensis

UniProt:

A4HNQ7_LEIBR

TriTrypDb:

LbrM.35.0580 , LBRM2903_350011300

Length:

341

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HNQ7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNQ7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	125	127	PF00675	0.611
CLV_NRD_NRD_1	137	139	PF00675	0.587
CLV_NRD_NRD_1	158	160	PF00675	0.722
CLV_NRD_NRD_1	161	163	PF00675	0.719
CLV_NRD_NRD_1	284	286	PF00675	0.683
CLV_PCSK_KEX2_1	127	129	PF00082	0.595
CLV_PCSK_KEX2_1	137	139	PF00082	0.588
CLV_PCSK_KEX2_1	200	202	PF00082	0.545
CLV_PCSK_KEX2_1	249	251	PF00082	0.767
CLV_PCSK_KEX2_1	284	286	PF00082	0.683
CLV_PCSK_KEX2_1	34	36	PF00082	0.496
CLV_PCSK_PC1ET2_1	127	129	PF00082	0.563
CLV_PCSK_PC1ET2_1	200	202	PF00082	0.608
CLV_PCSK_PC1ET2_1	249	251	PF00082	0.553
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.496
CLV_PCSK_SKI1_1	128	132	PF00082	0.634
CLV_PCSK_SKI1_1	197	201	PF00082	0.602
CLV_PCSK_SKI1_1	271	275	PF00082	0.529
CLV_PCSK_SKI1_1	31	35	PF00082	0.476
DOC_ANK_TNKS_1	137	144	PF00023	0.486
DOC_PP4_FxxP_1	152	155	PF00568	0.765
DOC_PP4_FxxP_1	227	230	PF00568	0.525
DOC_USP7_MATH_1	195	199	PF00917	0.520
DOC_USP7_MATH_1	238	242	PF00917	0.729
DOC_USP7_MATH_1	56	60	PF00917	0.623
DOC_USP7_MATH_1	67	71	PF00917	0.728
DOC_USP7_MATH_1	79	83	PF00917	0.691
DOC_USP7_UBL2_3	123	127	PF12436	0.522
DOC_USP7_UBL2_3	160	164	PF12436	0.627
DOC_USP7_UBL2_3	53	57	PF12436	0.770
DOC_WW_Pin1_4	173	178	PF00397	0.699
DOC_WW_Pin1_4	291	296	PF00397	0.696
LIG_14-3-3_CanoR_1	243	253	PF00244	0.769
LIG_FHA_1	246	252	PF00498	0.766
LIG_FHA_1	292	298	PF00498	0.663
LIG_FHA_1	327	333	PF00498	0.605
LIG_FHA_1	6	12	PF00498	0.372
LIG_LIR_Gen_1	109	117	PF02991	0.438
LIG_LIR_Nem_3	109	115	PF02991	0.438
LIG_LIR_Nem_3	212	218	PF02991	0.483
LIG_SH2_CRK	215	219	PF00017	0.499
LIG_SH2_NCK_1	175	179	PF00017	0.688
LIG_SH2_STAP1	29	33	PF00017	0.431
LIG_SH2_STAT5	175	178	PF00017	0.689
LIG_SH3_3	290	296	PF00018	0.812
LIG_SH3_3	37	43	PF00018	0.548
LIG_SH3_CIN85_PxpxPR_1	177	182	PF14604	0.482
LIG_SUMO_SIM_par_1	61	70	PF11976	0.506
LIG_UBA3_1	46	53	PF00899	0.456
MOD_CK1_1	173	179	PF00069	0.653
MOD_CK1_1	241	247	PF00069	0.724
MOD_CK2_1	56	62	PF00069	0.506
MOD_GlcNHglycan	139	142	PF01048	0.596
MOD_GlcNHglycan	155	158	PF01048	0.698
MOD_GlcNHglycan	17	20	PF01048	0.420
MOD_GlcNHglycan	197	200	PF01048	0.582
MOD_GlcNHglycan	220	223	PF01048	0.696
MOD_GlcNHglycan	231	234	PF01048	0.733
MOD_GlcNHglycan	77	80	PF01048	0.635
MOD_GSK3_1	166	173	PF00069	0.668
MOD_GSK3_1	214	221	PF00069	0.669
MOD_GSK3_1	238	245	PF00069	0.778
MOD_GSK3_1	298	305	PF00069	0.672
MOD_GSK3_1	56	63	PF00069	0.621
MOD_GSK3_1	75	82	PF00069	0.715
MOD_GSK3_1	89	96	PF00069	0.694
MOD_N-GLC_1	169	174	PF02516	0.714
MOD_N-GLC_1	327	332	PF02516	0.608
MOD_NEK2_1	131	136	PF00069	0.549
MOD_NEK2_1	166	171	PF00069	0.617
MOD_NEK2_1	209	214	PF00069	0.650
MOD_NEK2_1	218	223	PF00069	0.715
MOD_NEK2_2	214	219	PF00069	0.498
MOD_NEK2_2	238	243	PF00069	0.526
MOD_PIKK_1	67	73	PF00454	0.500
MOD_PKA_1	137	143	PF00069	0.482
MOD_PKA_2	137	143	PF00069	0.482
MOD_PKA_2	218	224	PF00069	0.519
MOD_PKA_2	242	248	PF00069	0.775
MOD_PKA_2	283	289	PF00069	0.678
MOD_PKA_2	298	304	PF00069	0.659
MOD_Plk_1	327	333	PF00069	0.608
MOD_Plk_1	61	67	PF00069	0.508
MOD_Plk_4	61	67	PF00069	0.626
MOD_ProDKin_1	173	179	PF00069	0.697
MOD_ProDKin_1	291	297	PF00069	0.699
TRG_ENDOCYTIC_2	215	218	PF00928	0.495
TRG_ER_diArg_1	137	139	PF00400	0.679
TRG_NLS_MonoCore_2	161	166	PF00514	0.550
TRG_NLS_MonoExtC_3	126	132	PF00514	0.552
TRG_NLS_MonoExtC_3	158	163	PF00514	0.616
TRG_NLS_MonoExtN_4	126	131	PF00514	0.438
TRG_NLS_MonoExtN_4	159	166	PF00514	0.530
TRG_Pf-PMV_PEXEL_1	81	86	PF00026	0.621

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYW4	Leptomonas seymouri	54%	92%
A0A1X0P958	Trypanosomatidae	42%	100%
A0A3S7XAD7	Leishmania donovani	78%	98%
A4ICT8	Leishmania infantum	78%	98%
E9ASG6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	98%
Q4Q229	Leishmania major	78%	100%
V5BQI1	Trypanosoma cruzi	40%	100%