Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HNP6_LEIBR

TriTrypDb:

LbrM.35.0470 , LBRM2903_350010100

Length:

146


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

A4HNP6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNP6


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	140	142	PF00675	0.627
CLV_NRD_NRD_1	144	146	PF00675	0.701
CLV_NRD_NRD_1	30	32	PF00675	0.537
CLV_PCSK_KEX2_1	144	146	PF00082	0.724
CLV_PCSK_KEX2_1	29	31	PF00082	0.545
CLV_PCSK_KEX2_1	99	101	PF00082	0.593
CLV_PCSK_PC1ET2_1	99	101	PF00082	0.593
CLV_PCSK_PC7_1	26	32	PF00082	0.559
CLV_PCSK_SKI1_1	31	35	PF00082	0.565
CLV_Separin_Metazoa	14	18	PF03568	0.421
DOC_USP7_MATH_1	62	66	PF00917	0.717
DOC_USP7_MATH_1	86	90	PF00917	0.633
DOC_USP7_UBL2_3	138	142	PF12436	0.596
DOC_WW_Pin1_4	113	118	PF00397	0.777
DOC_WW_Pin1_4	60	65	PF00397	0.650
LIG_BIR_II_1	1	5	PF00653	0.630
LIG_eIF4E_1	90	96	PF01652	0.440
LIG_FHA_1	114	120	PF00498	0.604
LIG_MYND_1	117	121	PF01753	0.529
LIG_NRBOX	91	97	PF00104	0.438
LIG_SH2_STAT3	75	78	PF00017	0.743
LIG_SH2_STAT3	90	93	PF00017	0.482
LIG_SH2_STAT5	53	56	PF00017	0.700
LIG_SH2_STAT5	90	93	PF00017	0.576
LIG_SH3_3	118	124	PF00018	0.739
LIG_UBA3_1	91	99	PF00899	0.657
MOD_CK1_1	63	69	PF00069	0.691
MOD_CK1_1	71	77	PF00069	0.677
MOD_CK2_1	131	137	PF00069	0.614
MOD_GlcNHglycan	110	113	PF01048	0.726
MOD_GlcNHglycan	45	49	PF01048	0.592
MOD_GlcNHglycan	65	68	PF01048	0.647
MOD_GSK3_1	104	111	PF00069	0.711
MOD_GSK3_1	56	63	PF00069	0.665
MOD_NEK2_1	56	61	PF00069	0.511
MOD_NEK2_1	70	75	PF00069	0.525
MOD_PIKK_1	104	110	PF00454	0.510
MOD_PIKK_1	125	131	PF00454	0.732
MOD_PKB_1	100	108	PF00069	0.503
MOD_Plk_1	131	137	PF00069	0.675
MOD_Plk_4	49	55	PF00069	0.724
MOD_Plk_4	86	92	PF00069	0.682
MOD_ProDKin_1	113	119	PF00069	0.776
MOD_ProDKin_1	60	66	PF00069	0.655
TRG_ENDOCYTIC_2	53	56	PF00928	0.644
TRG_ER_diArg_1	143	145	PF00400	0.698
TRG_ER_diArg_1	29	31	PF00400	0.560
TRG_NLS_MonoExtC_3	140	145	PF00514	0.649
TRG_NLS_MonoExtN_4	138	145	PF00514	0.653


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7D8	Leptomonas seymouri	47%	78%
A0A0S4JKZ0	Bodo saltans	35%	100%
A0A1X0P8A6	Trypanosomatidae	34%	100%
A0A3S7XA93	Leishmania donovani	73%	95%
A0A422P2F7	Trypanosoma rangeli	35%	100%
A4ICU9	Leishmania infantum	73%	95%
D0A2K4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
E9ASF5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	71%	95%
Q4Q240	Leishmania major	74%	100%
V5BV99	Trypanosoma cruzi	36%	100%