Calponin-homology (CH) domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HNN5_LEIBR

TriTrypDb:

LbrM.35.0350 , LBRM2903_350008900

Length:

809

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HNN5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNN5

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	90	94	PF00656	0.531
CLV_NRD_NRD_1	245	247	PF00675	0.622
CLV_NRD_NRD_1	256	258	PF00675	0.410
CLV_NRD_NRD_1	37	39	PF00675	0.602
CLV_NRD_NRD_1	489	491	PF00675	0.519
CLV_NRD_NRD_1	665	667	PF00675	0.791
CLV_NRD_NRD_1	733	735	PF00675	0.520
CLV_NRD_NRD_1	755	757	PF00675	0.408
CLV_NRD_NRD_1	794	796	PF00675	0.548
CLV_PCSK_KEX2_1	244	246	PF00082	0.740

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0J3	Leptomonas seymouri	42%	100%
A0A1X0P8E4	Trypanosomatidae	29%	96%
A0A3Q8IIY8	Leishmania donovani	72%	99%
A0A422P2B7	Trypanosoma rangeli	32%	100%
A4ICW0	Leishmania infantum	72%	99%
E9ASE4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	72%	99%
Q4Q251	Leishmania major	72%	100%

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