LeishMANIAdb
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Putative xylulokinase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative xylulokinase
Gene product:
xylulokinase, putative
Species:
Leishmania braziliensis
UniProt:
A4HNN4_LEIBR
TriTrypDb:
LbrM.35.0340
Length:
161

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Cellular components
Term Name Level Count
GO:0043226 organelle 2 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

A4HNN4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNN4

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 2
GO:0004856 xylulokinase activity 5 2
GO:0016301 kinase activity 4 2
GO:0016740 transferase activity 2 2
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 2
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 2
GO:0019200 carbohydrate kinase activity 5 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 112 114 PF00082 0.549
CLV_PCSK_KEX2_1 42 44 PF00082 0.549
CLV_PCSK_PC1ET2_1 112 114 PF00082 0.549
CLV_PCSK_PC1ET2_1 42 44 PF00082 0.549
CLV_PCSK_SKI1_1 91 95 PF00082 0.549
CLV_PCSK_SKI1_1 97 101 PF00082 0.444
DEG_APCC_DBOX_1 143 151 PF00400 0.781
DOC_MAPK_gen_1 117 125 PF00069 0.549
DOC_MAPK_gen_1 66 75 PF00069 0.549
DOC_MAPK_HePTP_8 63 75 PF00069 0.549
DOC_MAPK_MEF2A_6 117 125 PF00069 0.549
DOC_MAPK_MEF2A_6 66 75 PF00069 0.549
DOC_PP1_RVXF_1 146 153 PF00149 0.783
DOC_PP2B_LxvP_1 103 106 PF13499 0.549
DOC_PP2B_PxIxI_1 120 126 PF00149 0.549
DOC_WW_Pin1_4 129 134 PF00397 0.784
DOC_WW_Pin1_4 22 27 PF00397 0.783
LIG_14-3-3_CanoR_1 3 8 PF00244 0.834
LIG_FHA_1 59 65 PF00498 0.549
LIG_FHA_1 98 104 PF00498 0.549
LIG_FHA_2 34 40 PF00498 0.549
LIG_Integrin_isoDGR_2 142 144 PF01839 0.785
LIG_LIR_Nem_3 67 71 PF02991 0.549
LIG_SH2_CRK 68 72 PF00017 0.549
LIG_SH3_3 4 10 PF00018 0.817
MOD_CDK_SPxK_1 22 28 PF00069 0.790
MOD_CK1_1 55 61 PF00069 0.549
MOD_CK2_1 33 39 PF00069 0.549
MOD_Cter_Amidation 110 113 PF01082 0.549
MOD_GlcNHglycan 54 57 PF01048 0.549
MOD_GSK3_1 55 62 PF00069 0.549
MOD_GSK3_1 93 100 PF00069 0.549
MOD_N-GLC_1 33 38 PF02516 0.736
MOD_NEK2_1 15 20 PF00069 0.828
MOD_NEK2_1 64 69 PF00069 0.549
MOD_PIKK_1 9 15 PF00454 0.808
MOD_PKA_2 2 8 PF00069 0.838
MOD_PKA_2 20 26 PF00069 0.464
MOD_Plk_1 33 39 PF00069 0.549
MOD_Plk_4 59 65 PF00069 0.549
MOD_ProDKin_1 129 135 PF00069 0.783
MOD_ProDKin_1 22 28 PF00069 0.790
TRG_ENDOCYTIC_2 68 71 PF00928 0.549
TRG_ER_diArg_1 19 22 PF00400 0.801

Homologs

Protein Taxonomy Sequence identity Coverage
P09099 ECOLI 48% 33%
P29444 KLEPN 40% 33%
P39211 BACSU 40% 32%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS