p21 antigen protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

p21 antigen protein

Gene product:

Lsm12 protein, putative

Species:

Leishmania braziliensis

UniProt:

A4HNJ0_LEIBR

TriTrypDb:

LbrM.34.5230 , LBRM2903_340063100

Length:

191

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HNJ0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNJ0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	164	168	PF00082	0.766
CLV_PCSK_SKI1_1	91	95	PF00082	0.654
DOC_CKS1_1	160	165	PF01111	0.711
DOC_CKS1_1	53	58	PF01111	0.687
DOC_MAPK_MEF2A_6	34	43	PF00069	0.712
DOC_USP7_MATH_1	117	121	PF00917	0.664
DOC_USP7_MATH_1	185	189	PF00917	0.742
DOC_USP7_MATH_1	75	79	PF00917	0.768
DOC_USP7_UBL2_3	91	95	PF12436	0.759
DOC_WW_Pin1_4	159	164	PF00397	0.690
DOC_WW_Pin1_4	52	57	PF00397	0.670
LIG_APCC_ABBA_1	133	138	PF00400	0.692
LIG_BIR_II_1	1	5	PF00653	0.685
LIG_BIR_III_4	8	12	PF00653	0.695
LIG_eIF4E_1	13	19	PF01652	0.712
LIG_FHA_1	149	155	PF00498	0.748
LIG_FHA_1	53	59	PF00498	0.645
LIG_FHA_2	15	21	PF00498	0.639
LIG_GBD_Chelix_1	178	186	PF00786	0.708
LIG_LIR_Apic_2	157	163	PF02991	0.640
LIG_LIR_Gen_1	109	117	PF02991	0.759
LIG_LIR_Gen_1	125	135	PF02991	0.734
LIG_LIR_Gen_1	77	87	PF02991	0.736
LIG_LIR_Nem_3	109	115	PF02991	0.758
LIG_LIR_Nem_3	125	130	PF02991	0.560
LIG_LIR_Nem_3	77	82	PF02991	0.745
LIG_LYPXL_S_1	133	137	PF13949	0.614
LIG_LYPXL_yS_3	134	137	PF13949	0.605
LIG_SH2_CRK	13	17	PF00017	0.742
LIG_SH2_STAT5	127	130	PF00017	0.736
LIG_SH2_STAT5	57	60	PF00017	0.758
LIG_SH3_3	152	158	PF00018	0.704
LIG_SUMO_SIM_anti_2	149	157	PF11976	0.707
LIG_SUMO_SIM_anti_2	35	41	PF11976	0.538
LIG_SUMO_SIM_par_1	149	157	PF11976	0.707
LIG_WRC_WIRS_1	76	81	PF05994	0.789
MOD_CDK_SPK_2	159	164	PF00069	0.745
MOD_CDK_SPxxK_3	52	59	PF00069	0.674
MOD_CK1_1	120	126	PF00069	0.728
MOD_CK2_1	103	109	PF00069	0.703
MOD_CK2_1	19	25	PF00069	0.718
MOD_CK2_1	61	67	PF00069	0.724
MOD_CK2_1	75	81	PF00069	0.493
MOD_Cter_Amidation	188	191	PF01082	0.751
MOD_GlcNHglycan	187	190	PF01048	0.677
MOD_GSK3_1	116	123	PF00069	0.738
MOD_NEK2_1	14	19	PF00069	0.654
MOD_NEK2_1	61	66	PF00069	0.754
MOD_PIKK_1	96	102	PF00454	0.679
MOD_PK_1	59	65	PF00069	0.740
MOD_PK_1	89	95	PF00069	0.761
MOD_Plk_1	117	123	PF00069	0.528
MOD_Plk_1	59	65	PF00069	0.719
MOD_Plk_4	14	20	PF00069	0.603
MOD_Plk_4	148	154	PF00069	0.734
MOD_Plk_4	24	30	PF00069	0.582
MOD_Plk_4	89	95	PF00069	0.761
MOD_ProDKin_1	159	165	PF00069	0.692
MOD_ProDKin_1	52	58	PF00069	0.669
MOD_SUMO_rev_2	20	24	PF00179	0.726
TRG_DiLeu_BaEn_4	67	73	PF01217	0.775
TRG_ENDOCYTIC_2	127	130	PF00928	0.698
TRG_ENDOCYTIC_2	13	16	PF00928	0.707
TRG_ENDOCYTIC_2	134	137	PF00928	0.430

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZ22	Leptomonas seymouri	79%	100%
A0A0S4JPM5	Bodo saltans	33%	99%
A0A1X0P513	Trypanosomatidae	43%	100%
A0A3S7XA44	Leishmania donovani	93%	100%
A0A422N5Z2	Trypanosoma rangeli	46%	100%
A4IC47	Leishmania infantum	93%	100%
C9ZYC7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
E9B755	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
Q38E83	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	43%	100%
Q9U8C2	Leishmania major	91%	100%