Methyltransf_11 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HNH6_LEIBR

TriTrypDb:

LbrM.34.5080 , LBRM2903_340061300

Length:

287

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HNH6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNH6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	34	36	PF00675	0.610
CLV_NRD_NRD_1	42	44	PF00675	0.506
CLV_PCSK_KEX2_1	42	44	PF00082	0.431
DEG_Nend_UBRbox_3	1	3	PF02207	0.616
DEG_SPOP_SBC_1	106	110	PF00917	0.544
DOC_MAPK_gen_1	213	222	PF00069	0.312
DOC_MAPK_JIP1_4	216	222	PF00069	0.387
DOC_MAPK_MEF2A_6	113	122	PF00069	0.387
DOC_PP4_FxxP_1	19	22	PF00568	0.338
DOC_USP7_MATH_1	106	110	PF00917	0.535
DOC_USP7_MATH_1	156	160	PF00917	0.492
DOC_USP7_MATH_1	282	286	PF00917	0.385
DOC_WW_Pin1_4	149	154	PF00397	0.424
LIG_Actin_WH2_2	201	218	PF00022	0.321
LIG_Actin_WH2_2	249	264	PF00022	0.312
LIG_deltaCOP1_diTrp_1	14	19	PF00928	0.455
LIG_FHA_1	249	255	PF00498	0.318
LIG_FHA_1	3	9	PF00498	0.506
LIG_FHA_1	78	84	PF00498	0.450
LIG_HCF-1_HBM_1	17	20	PF13415	0.497
LIG_IBAR_NPY_1	233	235	PF08397	0.263
LIG_LIR_Apic_2	17	22	PF02991	0.347
LIG_LIR_Gen_1	14	24	PF02991	0.504
LIG_LIR_Nem_3	14	19	PF02991	0.494
LIG_LIR_Nem_3	271	276	PF02991	0.338
LIG_LIR_Nem_3	51	56	PF02991	0.358
LIG_NRBOX	125	131	PF00104	0.247
LIG_PAM2_1	191	203	PF00658	0.313
LIG_PCNA_yPIPBox_3	201	213	PF02747	0.325
LIG_Pex14_1	16	20	PF04695	0.415
LIG_Pex14_1	52	56	PF04695	0.342
LIG_Pex14_2	15	19	PF04695	0.417
LIG_Pex14_2	196	200	PF04695	0.454
LIG_SH2_CRK	278	282	PF00017	0.326
LIG_SH2_NCK_1	278	282	PF00017	0.344
LIG_SH2_SRC	59	62	PF00017	0.251
LIG_SH2_STAP1	250	254	PF00017	0.374
LIG_SH2_STAP1	278	282	PF00017	0.402
LIG_SH2_STAP1	50	54	PF00017	0.348
LIG_SH2_STAP1	59	63	PF00017	0.326
LIG_SH2_STAT5	235	238	PF00017	0.355
LIG_SH2_STAT5	250	253	PF00017	0.426
LIG_SH2_STAT5	278	281	PF00017	0.233
LIG_SH3_3	150	156	PF00018	0.490
LIG_SH3_3	228	234	PF00018	0.357
LIG_SUMO_SIM_anti_2	179	185	PF11976	0.308
LIG_SUMO_SIM_par_1	222	230	PF11976	0.425
LIG_SUMO_SIM_par_1	251	258	PF11976	0.284
LIG_TYR_ITIM	248	253	PF00017	0.424
LIG_WRC_WIRS_1	243	248	PF05994	0.417
MOD_CK1_1	108	114	PF00069	0.563
MOD_CK1_1	158	164	PF00069	0.383
MOD_CK1_1	165	171	PF00069	0.282
MOD_CK1_1	225	231	PF00069	0.467
MOD_GlcNHglycan	193	196	PF01048	0.307
MOD_GlcNHglycan	237	240	PF01048	0.373
MOD_GlcNHglycan	282	285	PF01048	0.430
MOD_GSK3_1	105	112	PF00069	0.608
MOD_GSK3_1	158	165	PF00069	0.422
MOD_GSK3_1	276	283	PF00069	0.260
MOD_LATS_1	263	269	PF00433	0.531
MOD_N-GLC_1	88	93	PF02516	0.259
MOD_N-GLC_2	143	145	PF02516	0.296
MOD_NEK2_1	107	112	PF00069	0.403
MOD_NEK2_1	147	152	PF00069	0.371
MOD_NEK2_1	222	227	PF00069	0.426
MOD_PIKK_1	255	261	PF00454	0.326
MOD_PKA_1	42	48	PF00069	0.398
MOD_PKA_2	165	171	PF00069	0.433
MOD_PKA_2	2	8	PF00069	0.467
MOD_PKA_2	42	48	PF00069	0.479
MOD_Plk_1	88	94	PF00069	0.266
MOD_Plk_4	158	164	PF00069	0.385
MOD_Plk_4	171	177	PF00069	0.316
MOD_Plk_4	203	209	PF00069	0.283
MOD_Plk_4	276	282	PF00069	0.289
MOD_Plk_4	42	48	PF00069	0.479
MOD_Plk_4	69	75	PF00069	0.434
MOD_ProDKin_1	149	155	PF00069	0.437
TRG_ENDOCYTIC_2	250	253	PF00928	0.425
TRG_ENDOCYTIC_2	278	281	PF00928	0.315
TRG_ENDOCYTIC_2	50	53	PF00928	0.354
TRG_NES_CRM1_1	171	185	PF08389	0.242

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HTH2	Leptomonas seymouri	62%	100%
A0A3S7XA23	Leishmania donovani	77%	100%
A4IC32	Leishmania infantum	77%	100%
E9AFY7	Leishmania major	76%	100%
E9B740	Leishmania mexicana (strain MHOM/GT/2001/U1103)	77%	100%
Q501S4	Danio rerio	25%	100%