Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HNG7_LEIBR

TriTrypDb:

LbrM.34.4990 , LBRM2903_340060400

Length:

645

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HNG7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNG7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	10	14	PF00656	0.603
CLV_C14_Caspase3-7	133	137	PF00656	0.644
CLV_NRD_NRD_1	172	174	PF00675	0.579
CLV_NRD_NRD_1	19	21	PF00675	0.775
CLV_NRD_NRD_1	370	372	PF00675	0.662
CLV_NRD_NRD_1	409	411	PF00675	0.648
CLV_NRD_NRD_1	458	460	PF00675	0.585
CLV_NRD_NRD_1	466	468	PF00675	0.547
CLV_NRD_NRD_1	517	519	PF00675	0.703
CLV_NRD_NRD_1	542	544	PF00675	0.693
CLV_NRD_NRD_1	580	582	PF00675	0.712
CLV_NRD_NRD_1	587	589	PF00675	0.646
CLV_PCSK_FUR_1	585	589	PF00082	0.709
CLV_PCSK_KEX2_1	172	174	PF00082	0.597
CLV_PCSK_KEX2_1	19	21	PF00082	0.685
CLV_PCSK_KEX2_1	370	372	PF00082	0.662
CLV_PCSK_KEX2_1	409	411	PF00082	0.648
CLV_PCSK_KEX2_1	458	460	PF00082	0.585
CLV_PCSK_KEX2_1	466	468	PF00082	0.547
CLV_PCSK_KEX2_1	517	519	PF00082	0.702
CLV_PCSK_KEX2_1	542	544	PF00082	0.693
CLV_PCSK_KEX2_1	580	582	PF00082	0.712
CLV_PCSK_KEX2_1	587	589	PF00082	0.646
CLV_PCSK_PC7_1	513	519	PF00082	0.702
CLV_PCSK_PC7_1	583	589	PF00082	0.563
CLV_PCSK_SKI1_1	240	244	PF00082	0.646
CLV_PCSK_SKI1_1	466	470	PF00082	0.566
CLV_PCSK_SKI1_1	58	62	PF00082	0.607
DEG_Nend_UBRbox_2	1	3	PF02207	0.635
DEG_SCF_FBW7_1	22	28	PF00400	0.481
DEG_SCF_FBW7_1	425	431	PF00400	0.558
DEG_SCF_FBW7_1	83	89	PF00400	0.558
DEG_SCF_TRCP1_1	136	142	PF00400	0.578
DEG_SPOP_SBC_1	40	44	PF00917	0.666
DEG_SPOP_SBC_1	556	560	PF00917	0.550
DOC_CDC14_PxL_1	533	541	PF14671	0.548
DOC_CDC14_PxL_1	92	100	PF14671	0.549
DOC_CKS1_1	22	27	PF01111	0.494
DOC_CKS1_1	285	290	PF01111	0.536
DOC_CKS1_1	425	430	PF01111	0.556
DOC_CKS1_1	564	569	PF01111	0.538
DOC_CKS1_1	83	88	PF01111	0.715
DOC_MAPK_RevD_3	356	371	PF00069	0.639
DOC_PP2B_LxvP_1	224	227	PF13499	0.664
DOC_PP2B_LxvP_1	262	265	PF13499	0.711
DOC_PP4_FxxP_1	272	275	PF00568	0.579
DOC_PP4_FxxP_1	285	288	PF00568	0.496
DOC_PP4_FxxP_1	336	339	PF00568	0.524
DOC_SPAK_OSR1_1	354	358	PF12202	0.653
DOC_USP7_MATH_1	132	136	PF00917	0.728
DOC_USP7_MATH_1	156	160	PF00917	0.660
DOC_USP7_MATH_1	197	201	PF00917	0.650
DOC_USP7_MATH_1	34	38	PF00917	0.543
DOC_USP7_MATH_1	379	383	PF00917	0.617
DOC_USP7_MATH_1	39	43	PF00917	0.605
DOC_USP7_MATH_1	506	510	PF00917	0.730
DOC_USP7_MATH_1	524	528	PF00917	0.559
DOC_USP7_MATH_1	556	560	PF00917	0.573
DOC_WW_Pin1_4	199	204	PF00397	0.721
DOC_WW_Pin1_4	208	213	PF00397	0.613
DOC_WW_Pin1_4	21	26	PF00397	0.502
DOC_WW_Pin1_4	218	223	PF00397	0.513
DOC_WW_Pin1_4	284	289	PF00397	0.578
DOC_WW_Pin1_4	306	311	PF00397	0.642
DOC_WW_Pin1_4	318	323	PF00397	0.617
DOC_WW_Pin1_4	335	340	PF00397	0.718
DOC_WW_Pin1_4	404	409	PF00397	0.563
DOC_WW_Pin1_4	421	426	PF00397	0.554
DOC_WW_Pin1_4	436	441	PF00397	0.662
DOC_WW_Pin1_4	44	49	PF00397	0.584
DOC_WW_Pin1_4	563	568	PF00397	0.621
DOC_WW_Pin1_4	575	580	PF00397	0.536
DOC_WW_Pin1_4	58	63	PF00397	0.701
DOC_WW_Pin1_4	618	623	PF00397	0.761
DOC_WW_Pin1_4	82	87	PF00397	0.812
LIG_14-3-3_CanoR_1	172	180	PF00244	0.594
LIG_14-3-3_CanoR_1	190	199	PF00244	0.508
LIG_14-3-3_CanoR_1	327	332	PF00244	0.548
LIG_14-3-3_CanoR_1	33	39	PF00244	0.582
LIG_14-3-3_CanoR_1	380	386	PF00244	0.617
LIG_14-3-3_CanoR_1	388	396	PF00244	0.572
LIG_14-3-3_CanoR_1	416	422	PF00244	0.624
LIG_14-3-3_CanoR_1	453	460	PF00244	0.609
LIG_APCC_ABBAyCdc20_2	466	472	PF00400	0.544
LIG_BRCT_BRCA1_1	108	112	PF00533	0.559
LIG_BRCT_BRCA1_1	204	208	PF00533	0.561
LIG_EVH1_1	262	266	PF00568	0.711
LIG_FHA_1	180	186	PF00498	0.651
LIG_FHA_1	26	32	PF00498	0.632
LIG_FHA_1	335	341	PF00498	0.549
LIG_FHA_1	389	395	PF00498	0.614
LIG_FHA_1	41	47	PF00498	0.668
LIG_FHA_1	48	54	PF00498	0.561
LIG_FHA_1	500	506	PF00498	0.642
LIG_FHA_1	528	534	PF00498	0.549
LIG_FHA_1	622	628	PF00498	0.652
LIG_FHA_1	87	93	PF00498	0.566
LIG_FHA_2	165	171	PF00498	0.581
LIG_FHA_2	293	299	PF00498	0.534
LIG_FHA_2	395	401	PF00498	0.644
LIG_FHA_2	430	436	PF00498	0.593
LIG_FHA_2	564	570	PF00498	0.617
LIG_LIR_Apic_2	270	275	PF02991	0.579
LIG_LIR_Apic_2	282	288	PF02991	0.503
LIG_LIR_Apic_2	334	339	PF02991	0.527
LIG_LIR_Apic_2	594	598	PF02991	0.652
LIG_LIR_Gen_1	352	361	PF02991	0.643
LIG_LIR_Nem_3	16	21	PF02991	0.581
LIG_LIR_Nem_3	352	358	PF02991	0.650
LIG_LIR_Nem_3	56	60	PF02991	0.681
LIG_MYND_1	473	477	PF01753	0.619
LIG_MYND_1	96	100	PF01753	0.694
LIG_RPA_C_Fungi	538	550	PF08784	0.687
LIG_SH2_CRK	57	61	PF00017	0.686
LIG_SH2_CRK	595	599	PF00017	0.663
LIG_SH2_CRK	71	75	PF00017	0.564
LIG_SH2_NCK_1	595	599	PF00017	0.663
LIG_SH2_STAT5	565	568	PF00017	0.538
LIG_SH3_1	19	25	PF00018	0.661
LIG_SH3_1	260	266	PF00018	0.712
LIG_SH3_3	19	25	PF00018	0.661
LIG_SH3_3	260	266	PF00018	0.778
LIG_SH3_3	28	34	PF00018	0.566
LIG_SH3_3	344	350	PF00018	0.800
LIG_SH3_3	35	41	PF00018	0.545
LIG_SH3_3	358	364	PF00018	0.634
LIG_SH3_3	42	48	PF00018	0.528
LIG_SH3_3	422	428	PF00018	0.655
LIG_SH3_3	430	436	PF00018	0.682
LIG_SH3_3	516	522	PF00018	0.574
LIG_SH3_3	561	567	PF00018	0.537
LIG_SH3_3	616	622	PF00018	0.670
LIG_SH3_3	77	83	PF00018	0.726
LIG_SH3_3	94	100	PF00018	0.597
LIG_SUMO_SIM_par_1	181	186	PF11976	0.581
LIG_SUMO_SIM_par_1	345	353	PF11976	0.509
LIG_TRAF2_1	381	384	PF00917	0.573
MOD_CDC14_SPxK_1	407	410	PF00782	0.559
MOD_CDC14_SPxK_1	578	581	PF00782	0.706
MOD_CDC14_SPxK_1	625	628	PF00782	0.673
MOD_CDK_SPK_2	404	409	PF00069	0.555
MOD_CDK_SPK_2	575	580	PF00069	0.709
MOD_CDK_SPK_2	82	87	PF00069	0.558
MOD_CDK_SPxK_1	404	410	PF00069	0.556
MOD_CDK_SPxK_1	575	581	PF00069	0.709
MOD_CDK_SPxK_1	622	628	PF00069	0.671
MOD_CDK_SPxxK_3	208	215	PF00069	0.548
MOD_CDK_SPxxK_3	335	342	PF00069	0.526
MOD_CK1_1	127	133	PF00069	0.702
MOD_CK1_1	137	143	PF00069	0.647
MOD_CK1_1	202	208	PF00069	0.778
MOD_CK1_1	211	217	PF00069	0.610
MOD_CK1_1	253	259	PF00069	0.709
MOD_CK1_1	270	276	PF00069	0.560
MOD_CK1_1	321	327	PF00069	0.567
MOD_CK1_1	335	341	PF00069	0.551
MOD_CK1_1	390	396	PF00069	0.539
MOD_CK1_1	417	423	PF00069	0.650
MOD_CK1_1	424	430	PF00069	0.660
MOD_CK1_1	451	457	PF00069	0.614
MOD_CK1_1	47	53	PF00069	0.583
MOD_CK1_1	527	533	PF00069	0.571
MOD_CK1_1	545	551	PF00069	0.637
MOD_CK1_1	591	597	PF00069	0.669
MOD_CK1_1	601	607	PF00069	0.572
MOD_CK1_1	621	627	PF00069	0.483
MOD_CK1_1	88	94	PF00069	0.728
MOD_CK2_1	148	154	PF00069	0.607
MOD_CK2_1	292	298	PF00069	0.629
MOD_CK2_1	394	400	PF00069	0.641
MOD_CK2_1	429	435	PF00069	0.614
MOD_CK2_1	563	569	PF00069	0.545
MOD_CK2_1	607	613	PF00069	0.555
MOD_CK2_1	637	643	PF00069	0.538
MOD_DYRK1A_RPxSP_1	438	442	PF00069	0.732
MOD_DYRK1A_RPxSP_1	618	622	PF00069	0.631
MOD_DYRK1A_RPxSP_1	82	86	PF00069	0.711
MOD_GlcNHglycan	130	133	PF01048	0.593
MOD_GlcNHglycan	136	139	PF01048	0.585
MOD_GlcNHglycan	156	159	PF01048	0.662
MOD_GlcNHglycan	255	258	PF01048	0.605
MOD_GlcNHglycan	364	367	PF01048	0.715
MOD_GlcNHglycan	510	513	PF01048	0.604
MOD_GlcNHglycan	526	529	PF01048	0.587
MOD_GlcNHglycan	569	573	PF01048	0.651
MOD_GlcNHglycan	608	612	PF01048	0.674
MOD_GSK3_1	102	109	PF00069	0.764
MOD_GSK3_1	124	131	PF00069	0.727
MOD_GSK3_1	195	202	PF00069	0.666
MOD_GSK3_1	21	28	PF00069	0.581
MOD_GSK3_1	213	220	PF00069	0.536
MOD_GSK3_1	306	313	PF00069	0.556
MOD_GSK3_1	317	324	PF00069	0.609
MOD_GSK3_1	327	334	PF00069	0.599
MOD_GSK3_1	390	397	PF00069	0.628
MOD_GSK3_1	40	47	PF00069	0.637
MOD_GSK3_1	417	424	PF00069	0.691
MOD_GSK3_1	448	455	PF00069	0.700
MOD_GSK3_1	495	502	PF00069	0.574
MOD_GSK3_1	614	621	PF00069	0.695
MOD_GSK3_1	78	85	PF00069	0.726
MOD_LATS_1	499	505	PF00433	0.564
MOD_N-GLC_1	506	511	PF02516	0.588
MOD_NEK2_1	250	255	PF00069	0.674
MOD_NEK2_1	311	316	PF00069	0.701
MOD_NEK2_1	331	336	PF00069	0.494
MOD_NEK2_1	429	434	PF00069	0.665
MOD_PIKK_1	379	385	PF00454	0.542
MOD_PIKK_1	453	459	PF00454	0.665
MOD_PIKK_1	548	554	PF00454	0.684
MOD_PIKK_1	637	643	PF00454	0.536
MOD_PK_1	543	549	PF00069	0.537
MOD_PK_1	588	594	PF00069	0.542
MOD_PKA_1	172	178	PF00069	0.579
MOD_PKA_1	458	464	PF00069	0.582
MOD_PKA_1	542	548	PF00069	0.686
MOD_PKA_2	102	108	PF00069	0.747
MOD_PKA_2	128	134	PF00069	0.607
MOD_PKA_2	172	178	PF00069	0.673
MOD_PKA_2	189	195	PF00069	0.544
MOD_PKA_2	253	259	PF00069	0.595
MOD_PKA_2	32	38	PF00069	0.735
MOD_PKA_2	326	332	PF00069	0.558
MOD_PKA_2	379	385	PF00069	0.615
MOD_PKA_2	387	393	PF00069	0.573
MOD_PKA_2	403	409	PF00069	0.665
MOD_PKA_2	415	421	PF00069	0.597
MOD_PKA_2	452	458	PF00069	0.612
MOD_PKA_2	542	548	PF00069	0.686
MOD_PKA_2	86	92	PF00069	0.606
MOD_Plk_1	228	234	PF00069	0.495
MOD_Plk_1	301	307	PF00069	0.697
MOD_Plk_1	350	356	PF00069	0.720
MOD_Plk_1	461	467	PF00069	0.649
MOD_Plk_1	543	549	PF00069	0.537
MOD_Plk_4	286	292	PF00069	0.549
MOD_Plk_4	327	333	PF00069	0.545
MOD_Plk_4	390	396	PF00069	0.686
MOD_Plk_4	41	47	PF00069	0.547
MOD_Plk_4	471	477	PF00069	0.650
MOD_Plk_4	598	604	PF00069	0.666
MOD_ProDKin_1	199	205	PF00069	0.719
MOD_ProDKin_1	208	214	PF00069	0.612
MOD_ProDKin_1	21	27	PF00069	0.498
MOD_ProDKin_1	218	224	PF00069	0.512
MOD_ProDKin_1	284	290	PF00069	0.579
MOD_ProDKin_1	306	312	PF00069	0.642
MOD_ProDKin_1	318	324	PF00069	0.617
MOD_ProDKin_1	335	341	PF00069	0.720
MOD_ProDKin_1	404	410	PF00069	0.565
MOD_ProDKin_1	421	427	PF00069	0.555
MOD_ProDKin_1	436	442	PF00069	0.660
MOD_ProDKin_1	44	50	PF00069	0.582
MOD_ProDKin_1	563	569	PF00069	0.624
MOD_ProDKin_1	575	581	PF00069	0.535
MOD_ProDKin_1	58	64	PF00069	0.700
MOD_ProDKin_1	618	624	PF00069	0.759
MOD_ProDKin_1	82	88	PF00069	0.811
TRG_DiLeu_BaLyEn_6	307	312	PF01217	0.531
TRG_DiLeu_BaLyEn_6	464	469	PF01217	0.590
TRG_DiLeu_BaLyEn_6	94	99	PF01217	0.704
TRG_ENDOCYTIC_2	57	60	PF00928	0.690
TRG_ER_diArg_1	172	174	PF00400	0.579
TRG_ER_diArg_1	18	20	PF00400	0.687
TRG_ER_diArg_1	370	373	PF00400	0.663
TRG_ER_diArg_1	408	410	PF00400	0.640
TRG_ER_diArg_1	458	460	PF00400	0.585
TRG_ER_diArg_1	465	467	PF00400	0.554
TRG_ER_diArg_1	517	519	PF00400	0.699
TRG_ER_diArg_1	541	543	PF00400	0.576
TRG_ER_diArg_1	579	581	PF00400	0.703
TRG_ER_diArg_1	585	588	PF00400	0.652
TRG_Pf-PMV_PEXEL_1	409	413	PF00026	0.647
TRG_Pf-PMV_PEXEL_1	467	472	PF00026	0.635

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H810	Leishmania donovani	59%	100%
A4IC58	Leishmania infantum	57%	100%
E9AFX8	Leishmania major	59%	100%
E9B731	Leishmania mexicana (strain MHOM/GT/2001/U1103)	61%	100%