Peroxin-13

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Peroxin-13

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HNF9_LEIBR

TriTrypDb:

LbrM.34.4910 , LBRM2903_340059500

Length:

208

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9
GO:0005777	peroxisome	6	1
GO:0042579	microbody	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

A4HNF9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNF9

Function

Biological processes
Term	Name	Level	Count
GO:0008104	protein localization	4	1
GO:0009987	cellular process	1	1
GO:0016560	protein import into peroxisome matrix, docking	5	1
GO:0033036	macromolecule localization	2	1
GO:0051179	localization	1	1
GO:0051641	cellular localization	2	1
GO:0070727	cellular macromolecule localization	3	1

Could not find GO molecular_function term for this entry.

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	119	121	PF00675	0.616
CLV_NRD_NRD_1	124	126	PF00675	0.598
CLV_NRD_NRD_1	140	142	PF00675	0.573
CLV_NRD_NRD_1	144	146	PF00675	0.509
CLV_PCSK_KEX2_1	140	142	PF00082	0.645
CLV_PCSK_KEX2_1	175	177	PF00082	0.426
CLV_PCSK_PC1ET2_1	175	177	PF00082	0.447
CLV_PCSK_PC7_1	136	142	PF00082	0.665
CLV_PCSK_SKI1_1	125	129	PF00082	0.660
CLV_PCSK_SKI1_1	175	179	PF00082	0.409
CLV_PCSK_SKI1_1	187	191	PF00082	0.497
DEG_APCC_DBOX_1	124	132	PF00400	0.453
DOC_CYCLIN_RxL_1	184	193	PF00134	0.671
DOC_CYCLIN_yClb1_LxF_4	147	152	PF00134	0.316
DOC_MAPK_gen_1	143	152	PF00069	0.478
DOC_MAPK_gen_1	159	167	PF00069	0.204
DOC_MAPK_JIP1_4	146	152	PF00069	0.319
DOC_PP1_RVXF_1	146	153	PF00149	0.370
DOC_WW_Pin1_4	52	57	PF00397	0.670
LIG_14-3-3_CanoR_1	176	181	PF00244	0.571
LIG_Actin_WH2_2	146	164	PF00022	0.466
LIG_deltaCOP1_diTrp_1	73	78	PF00928	0.491
LIG_FHA_1	176	182	PF00498	0.572
LIG_FHA_1	66	72	PF00498	0.559
LIG_LIR_Nem_3	21	27	PF02991	0.415
LIG_LIR_Nem_3	73	78	PF02991	0.470
LIG_LIR_Nem_3	95	99	PF02991	0.364
LIG_PDZ_Class_1	203	208	PF00595	0.640
LIG_Pex14_2	152	156	PF04695	0.427
LIG_SH2_CRK	27	31	PF00017	0.445
LIG_SH2_CRK	36	40	PF00017	0.440
LIG_SH2_PTP2	96	99	PF00017	0.376
LIG_SH2_STAT5	171	174	PF00017	0.347
LIG_SH2_STAT5	18	21	PF00017	0.338
LIG_SH2_STAT5	96	99	PF00017	0.359
LIG_SxIP_EBH_1	124	133	PF03271	0.422
MOD_CK1_1	201	207	PF00069	0.663
MOD_CK2_1	190	196	PF00069	0.658
MOD_Cter_Amidation	185	188	PF01082	0.451
MOD_GlcNHglycan	190	193	PF01048	0.513
MOD_GlcNHglycan	20	23	PF01048	0.697
MOD_GlcNHglycan	8	11	PF01048	0.655
MOD_GlcNHglycan	87	90	PF01048	0.337
MOD_GSK3_1	171	178	PF00069	0.620
MOD_GSK3_1	199	206	PF00069	0.760
MOD_NEK2_1	190	195	PF00069	0.726
MOD_NEK2_1	65	70	PF00069	0.594
MOD_NEK2_1	82	87	PF00069	0.395
MOD_NMyristoyl	1	7	PF02799	0.417
MOD_PIKK_1	76	82	PF00454	0.300
MOD_PIKK_1	97	103	PF00454	0.316
MOD_PKA_1	148	154	PF00069	0.392
MOD_PKA_1	175	181	PF00069	0.509
MOD_PKA_2	139	145	PF00069	0.429
MOD_PKA_2	175	181	PF00069	0.531
MOD_Plk_4	148	154	PF00069	0.446
MOD_Plk_4	176	182	PF00069	0.543
MOD_ProDKin_1	52	58	PF00069	0.665
TRG_DiLeu_BaLyEn_6	156	161	PF01217	0.395
TRG_ENDOCYTIC_2	27	30	PF00928	0.417
TRG_ENDOCYTIC_2	36	39	PF00928	0.371
TRG_ENDOCYTIC_2	96	99	PF00928	0.359
TRG_ER_diArg_1	139	141	PF00400	0.439
TRG_NLS_MonoCore_2	144	149	PF00514	0.439
TRG_NLS_MonoExtC_3	144	149	PF00514	0.391
TRG_NLS_MonoExtN_4	143	149	PF00514	0.411
TRG_PTS1	205	208	PF00515	0.641

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2X3	Leptomonas seymouri	69%	72%
A0A0S4J7P3	Bodo saltans	32%	69%
A0A0S4J8A4	Bodo saltans	31%	69%
A0A1X0P507	Trypanosomatidae	32%	73%
A0A3Q8IVL9	Leishmania donovani	81%	100%
A4IC72	Leishmania infantum	78%	100%
E9AFX0	Leishmania major	79%	100%
E9B723	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%