LeishMANIAdb
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Heat shock protein 70

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Heat shock protein 70
Gene product:
Hsp70 protein, putative
Species:
Leishmania braziliensis
UniProt:
A4HND7_LEIBR
TriTrypDb:
LbrM.34.4680 , LBRM2903_340057400
Length:
724

Annotations

LeishMANIAdb annotations

Appears to be a secreted chaperone, related to mammalian HYOU1 proteins. Probably ER-localized as in other eukaryotes

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 20
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 8
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 11, no: 3
NetGPI no yes: 0, no: 14
Cellular components
Term Name Level Count
GO:0043226 organelle 2 14
GO:0110165 cellular anatomical entity 1 14
GO:0032991 protein-containing complex 1 1
GO:0034663 endoplasmic reticulum chaperone complex 3 1
GO:0140534 endoplasmic reticulum protein-containing complex 2 1
GO:0016020 membrane 2 1

Expansion

Sequence features

A4HND7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HND7

Function

Biological processes
Term Name Level Count
GO:0001666 response to hypoxia 3 1
GO:0006950 response to stress 2 1
GO:0009628 response to abiotic stimulus 2 1
GO:0009966 regulation of signal transduction 4 1
GO:0009968 negative regulation of signal transduction 5 1
GO:0009987 cellular process 1 1
GO:0010646 regulation of cell communication 4 1
GO:0010648 negative regulation of cell communication 5 1
GO:0010941 regulation of cell death 4 1
GO:0023051 regulation of signaling 3 1
GO:0023057 negative regulation of signaling 4 1
GO:0033554 cellular response to stress 3 1
GO:0036293 response to decreased oxygen levels 4 1
GO:0036294 cellular response to decreased oxygen levels 5 1
GO:0042221 response to chemical 2 1
GO:0042981 regulation of apoptotic process 6 1
GO:0043066 negative regulation of apoptotic process 7 1
GO:0043067 regulation of programmed cell death 5 1
GO:0043069 negative regulation of programmed cell death 6 1
GO:0048519 negative regulation of biological process 3 1
GO:0048523 negative regulation of cellular process 4 1
GO:0048583 regulation of response to stimulus 3 1
GO:0048585 negative regulation of response to stimulus 4 1
GO:0050789 regulation of biological process 2 1
GO:0050794 regulation of cellular process 3 1
GO:0050896 response to stimulus 1 1
GO:0051716 cellular response to stimulus 2 1
GO:0060548 negative regulation of cell death 5 1
GO:0065007 biological regulation 1 1
GO:0070482 response to oxygen levels 3 1
GO:0070887 cellular response to chemical stimulus 3 1
GO:0071453 cellular response to oxygen levels 4 1
GO:0071456 cellular response to hypoxia 4 1
GO:0080134 regulation of response to stress 4 1
GO:0080135 regulation of cellular response to stress 4 1
GO:1900037 regulation of cellular response to hypoxia 5 1
GO:1900038 negative regulation of cellular response to hypoxia 5 1
GO:1902531 regulation of intracellular signal transduction 5 1
GO:1902532 negative regulation of intracellular signal transduction 6 1
GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway 7 1
GO:1903298 negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway 6 1
GO:2001233 regulation of apoptotic signaling pathway 5 1
GO:2001234 negative regulation of apoptotic signaling pathway 6 1
GO:2001242 regulation of intrinsic apoptotic signaling pathway 6 1
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 7 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 15
GO:0005488 binding 1 15
GO:0005524 ATP binding 5 15
GO:0017076 purine nucleotide binding 4 15
GO:0030554 adenyl nucleotide binding 5 15
GO:0032553 ribonucleotide binding 3 15
GO:0032555 purine ribonucleotide binding 4 15
GO:0032559 adenyl ribonucleotide binding 5 15
GO:0035639 purine ribonucleoside triphosphate binding 4 15
GO:0036094 small molecule binding 2 15
GO:0043167 ion binding 2 15
GO:0043168 anion binding 3 15
GO:0044183 protein folding chaperone 1 15
GO:0097159 organic cyclic compound binding 2 15
GO:0097367 carbohydrate derivative binding 2 15
GO:0140657 ATP-dependent activity 1 15
GO:0140662 ATP-dependent protein folding chaperone 2 15
GO:1901265 nucleoside phosphate binding 3 15
GO:1901363 heterocyclic compound binding 2 15

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 486 490 PF00656 0.347
CLV_NRD_NRD_1 177 179 PF00675 0.431
CLV_NRD_NRD_1 455 457 PF00675 0.391
CLV_NRD_NRD_1 57 59 PF00675 0.342
CLV_NRD_NRD_1 694 696 PF00675 0.491
CLV_NRD_NRD_1 98 100 PF00675 0.479
CLV_PCSK_KEX2_1 177 179 PF00082 0.395
CLV_PCSK_KEX2_1 241 243 PF00082 0.347
CLV_PCSK_KEX2_1 455 457 PF00082 0.393
CLV_PCSK_KEX2_1 57 59 PF00082 0.479
CLV_PCSK_PC1ET2_1 241 243 PF00082 0.404
CLV_PCSK_SKI1_1 178 182 PF00082 0.453
CLV_PCSK_SKI1_1 427 431 PF00082 0.426
CLV_PCSK_SKI1_1 456 460 PF00082 0.365
CLV_PCSK_SKI1_1 503 507 PF00082 0.392
CLV_PCSK_SKI1_1 573 577 PF00082 0.481
CLV_PCSK_SKI1_1 6 10 PF00082 0.525
DEG_APCC_DBOX_1 454 462 PF00400 0.404
DEG_Nend_UBRbox_1 1 4 PF02207 0.623
DOC_CYCLIN_RxL_1 424 434 PF00134 0.479
DOC_CYCLIN_RxL_1 451 463 PF00134 0.407
DOC_MAPK_gen_1 2 10 PF00069 0.618
DOC_MAPK_gen_1 278 286 PF00069 0.404
DOC_MAPK_gen_1 310 317 PF00069 0.397
DOC_MAPK_gen_1 57 66 PF00069 0.346
DOC_MAPK_gen_1 579 587 PF00069 0.323
DOC_MAPK_gen_1 99 107 PF00069 0.468
DOC_MAPK_MEF2A_6 492 499 PF00069 0.396
DOC_PP1_RVXF_1 216 223 PF00149 0.479
DOC_PP1_RVXF_1 4 10 PF00149 0.527
DOC_PP1_RVXF_1 436 442 PF00149 0.465
DOC_USP7_MATH_1 125 129 PF00917 0.473
DOC_USP7_MATH_1 20 24 PF00917 0.637
DOC_USP7_MATH_1 244 248 PF00917 0.493
DOC_USP7_MATH_1 493 497 PF00917 0.404
DOC_USP7_MATH_1 519 523 PF00917 0.445
DOC_USP7_MATH_2 596 602 PF00917 0.280
DOC_USP7_UBL2_3 569 573 PF12436 0.457
DOC_WW_Pin1_4 170 175 PF00397 0.502
DOC_WW_Pin1_4 318 323 PF00397 0.392
DOC_WW_Pin1_4 381 386 PF00397 0.392
DOC_WW_Pin1_4 418 423 PF00397 0.409
LIG_14-3-3_CanoR_1 242 252 PF00244 0.241
LIG_14-3-3_CanoR_1 340 344 PF00244 0.445
LIG_14-3-3_CanoR_1 456 462 PF00244 0.416
LIG_14-3-3_CanoR_1 492 498 PF00244 0.423
LIG_14-3-3_CanoR_1 508 513 PF00244 0.229
LIG_14-3-3_CanoR_1 57 66 PF00244 0.381
LIG_14-3-3_CanoR_1 624 631 PF00244 0.444
LIG_14-3-3_CanoR_1 695 705 PF00244 0.241
LIG_AP2alpha_2 134 136 PF02296 0.493
LIG_APCC_ABBA_1 109 114 PF00400 0.429
LIG_BRCT_BRCA1_1 105 109 PF00533 0.424
LIG_BRCT_BRCA1_1 245 249 PF00533 0.493
LIG_BRCT_BRCA1_1 470 474 PF00533 0.468
LIG_BRCT_BRCA1_1 480 484 PF00533 0.383
LIG_Clathr_ClatBox_1 536 540 PF01394 0.392
LIG_FHA_1 149 155 PF00498 0.500
LIG_FHA_1 252 258 PF00498 0.352
LIG_FHA_1 312 318 PF00498 0.472
LIG_FHA_1 382 388 PF00498 0.392
LIG_FHA_1 532 538 PF00498 0.440
LIG_FHA_1 566 572 PF00498 0.348
LIG_FHA_1 586 592 PF00498 0.419
LIG_FHA_1 707 713 PF00498 0.760
LIG_FHA_2 135 141 PF00498 0.374
LIG_FHA_2 225 231 PF00498 0.361
LIG_FHA_2 484 490 PF00498 0.339
LIG_FHA_2 598 604 PF00498 0.459
LIG_FHA_2 636 642 PF00498 0.449
LIG_GBD_Chelix_1 24 32 PF00786 0.493
LIG_LIR_Apic_2 590 596 PF02991 0.393
LIG_LIR_Gen_1 139 148 PF02991 0.392
LIG_LIR_Gen_1 300 308 PF02991 0.409
LIG_LIR_Gen_1 34 42 PF02991 0.371
LIG_LIR_Gen_1 348 359 PF02991 0.398
LIG_LIR_Gen_1 368 377 PF02991 0.241
LIG_LIR_Gen_1 491 502 PF02991 0.496
LIG_LIR_Nem_3 106 111 PF02991 0.256
LIG_LIR_Nem_3 139 145 PF02991 0.452
LIG_LIR_Nem_3 246 252 PF02991 0.395
LIG_LIR_Nem_3 300 305 PF02991 0.409
LIG_LIR_Nem_3 34 39 PF02991 0.371
LIG_LIR_Nem_3 348 354 PF02991 0.398
LIG_LIR_Nem_3 368 372 PF02991 0.506
LIG_LIR_Nem_3 491 497 PF02991 0.446
LIG_LIR_Nem_3 60 66 PF02991 0.364
LIG_LIR_Nem_3 638 643 PF02991 0.393
LIG_MLH1_MIPbox_1 105 109 PF16413 0.241
LIG_OCRL_FandH_1 107 119 PF00620 0.241
LIG_PCNA_TLS_4 628 635 PF02747 0.409
LIG_PDZ_Class_3 719 724 PF00595 0.798
LIG_Pex14_2 245 249 PF04695 0.241
LIG_Pex14_2 480 484 PF04695 0.493
LIG_PTB_Apo_2 363 370 PF02174 0.493
LIG_SH2_CRK 142 146 PF00017 0.459
LIG_SH2_CRK 5 9 PF00017 0.406
LIG_SH2_PTP2 36 39 PF00017 0.392
LIG_SH2_SRC 113 116 PF00017 0.493
LIG_SH2_SRC 541 544 PF00017 0.356
LIG_SH2_STAP1 113 117 PF00017 0.493
LIG_SH2_STAP1 142 146 PF00017 0.396
LIG_SH2_STAP1 416 420 PF00017 0.409
LIG_SH2_STAP1 541 545 PF00017 0.385
LIG_SH2_STAP1 548 552 PF00017 0.379
LIG_SH2_STAP1 687 691 PF00017 0.428
LIG_SH2_STAT5 148 151 PF00017 0.379
LIG_SH2_STAT5 323 326 PF00017 0.479
LIG_SH2_STAT5 36 39 PF00017 0.407
LIG_SH2_STAT5 485 488 PF00017 0.357
LIG_SH2_STAT5 634 637 PF00017 0.380
LIG_SH2_STAT5 72 75 PF00017 0.479
LIG_SH3_3 155 161 PF00018 0.409
LIG_SH3_3 163 169 PF00018 0.409
LIG_SH3_3 36 42 PF00018 0.377
LIG_SH3_3 440 446 PF00018 0.482
LIG_SH3_4 569 576 PF00018 0.241
LIG_Sin3_3 542 549 PF02671 0.241
LIG_SUMO_SIM_par_1 124 131 PF11976 0.493
LIG_SUMO_SIM_par_1 313 319 PF11976 0.362
LIG_SUMO_SIM_par_1 583 588 PF11976 0.366
LIG_TRAF2_1 137 140 PF00917 0.364
LIG_TRAF2_1 368 371 PF00917 0.241
LIG_TRAF2_1 600 603 PF00917 0.479
LIG_TRAF2_1 667 670 PF00917 0.469
LIG_TYR_ITIM 3 8 PF00017 0.416
LIG_TYR_ITSM 636 643 PF00017 0.241
LIG_UBA3_1 387 393 PF00899 0.452
LIG_UBA3_1 95 100 PF00899 0.280
LIG_WRC_WIRS_1 104 109 PF05994 0.454
LIG_WRC_WIRS_1 372 377 PF05994 0.479
MOD_CDK_SPK_2 381 386 PF00069 0.392
MOD_CDK_SPxxK_3 170 177 PF00069 0.479
MOD_CK1_1 226 232 PF00069 0.364
MOD_CK1_1 300 306 PF00069 0.398
MOD_CK1_1 316 322 PF00069 0.298
MOD_CK1_1 336 342 PF00069 0.457
MOD_CK1_1 511 517 PF00069 0.429
MOD_CK1_1 565 571 PF00069 0.370
MOD_CK1_1 699 705 PF00069 0.464
MOD_CK2_1 134 140 PF00069 0.356
MOD_CK2_1 224 230 PF00069 0.362
MOD_CK2_1 365 371 PF00069 0.404
MOD_CK2_1 597 603 PF00069 0.427
MOD_CK2_1 635 641 PF00069 0.401
MOD_GlcNHglycan 123 126 PF01048 0.452
MOD_GlcNHglycan 186 189 PF01048 0.482
MOD_GlcNHglycan 246 249 PF01048 0.465
MOD_GlcNHglycan 293 296 PF01048 0.502
MOD_GlcNHglycan 89 92 PF01048 0.464
MOD_GSK3_1 121 128 PF00069 0.423
MOD_GSK3_1 140 147 PF00069 0.474
MOD_GSK3_1 466 473 PF00069 0.375
MOD_GSK3_1 474 481 PF00069 0.315
MOD_GSK3_1 493 500 PF00069 0.324
MOD_GSK3_1 504 511 PF00069 0.263
MOD_GSK3_1 53 60 PF00069 0.359
MOD_GSK3_1 558 565 PF00069 0.375
MOD_GSK3_1 594 601 PF00069 0.389
MOD_GSK3_1 649 656 PF00069 0.364
MOD_GSK3_1 682 689 PF00069 0.484
MOD_GSK3_1 706 713 PF00069 0.711
MOD_GSK3_1 99 106 PF00069 0.295
MOD_N-GLC_1 213 218 PF02516 0.377
MOD_N-GLC_1 365 370 PF02516 0.453
MOD_N-GLC_1 474 479 PF02516 0.343
MOD_N-GLC_1 519 524 PF02516 0.386
MOD_N-GLC_1 531 536 PF02516 0.342
MOD_N-GLC_1 558 563 PF02516 0.378
MOD_NEK2_1 144 149 PF00069 0.479
MOD_NEK2_1 194 199 PF00069 0.376
MOD_NEK2_1 224 229 PF00069 0.438
MOD_NEK2_1 334 339 PF00069 0.315
MOD_NEK2_1 431 436 PF00069 0.441
MOD_NEK2_1 466 471 PF00069 0.456
MOD_NEK2_1 531 536 PF00069 0.413
MOD_NEK2_1 587 592 PF00069 0.326
MOD_NEK2_1 604 609 PF00069 0.393
MOD_NEK2_1 623 628 PF00069 0.163
MOD_NEK2_1 649 654 PF00069 0.372
MOD_NEK2_2 213 218 PF00069 0.452
MOD_PIKK_1 297 303 PF00454 0.387
MOD_PIKK_1 550 556 PF00454 0.500
MOD_PIKK_1 604 610 PF00454 0.500
MOD_PKA_1 57 63 PF00069 0.479
MOD_PKA_1 99 105 PF00069 0.479
MOD_PKA_2 184 190 PF00069 0.435
MOD_PKA_2 311 317 PF00069 0.420
MOD_PKA_2 339 345 PF00069 0.449
MOD_PKA_2 57 63 PF00069 0.364
MOD_PKA_2 623 629 PF00069 0.423
MOD_Plk_1 213 219 PF00069 0.377
MOD_Plk_1 259 265 PF00069 0.353
MOD_Plk_1 365 371 PF00069 0.442
MOD_Plk_1 399 405 PF00069 0.395
MOD_Plk_1 431 437 PF00069 0.473
MOD_Plk_1 478 484 PF00069 0.367
MOD_Plk_1 519 525 PF00069 0.365
MOD_Plk_1 571 577 PF00069 0.454
MOD_Plk_1 663 669 PF00069 0.493
MOD_Plk_2-3 371 377 PF00069 0.479
MOD_Plk_2-3 598 604 PF00069 0.435
MOD_Plk_4 103 109 PF00069 0.424
MOD_Plk_4 140 146 PF00069 0.484
MOD_Plk_4 360 366 PF00069 0.449
MOD_Plk_4 511 517 PF00069 0.308
MOD_Plk_4 610 616 PF00069 0.443
MOD_Plk_4 630 636 PF00069 0.259
MOD_ProDKin_1 170 176 PF00069 0.502
MOD_ProDKin_1 318 324 PF00069 0.392
MOD_ProDKin_1 381 387 PF00069 0.392
MOD_ProDKin_1 418 424 PF00069 0.409
MOD_SUMO_rev_2 128 135 PF00179 0.497
MOD_SUMO_rev_2 563 571 PF00179 0.480
TRG_DiLeu_BaEn_3 139 145 PF01217 0.409
TRG_DiLeu_BaEn_3 706 712 PF01217 0.762
TRG_ENDOCYTIC_2 142 145 PF00928 0.396
TRG_ENDOCYTIC_2 204 207 PF00928 0.392
TRG_ENDOCYTIC_2 234 237 PF00928 0.499
TRG_ENDOCYTIC_2 36 39 PF00928 0.401
TRG_ENDOCYTIC_2 5 8 PF00928 0.407
TRG_ENDOCYTIC_2 640 643 PF00928 0.352
TRG_ER_diArg_1 207 210 PF00400 0.392
TRG_ER_diArg_1 455 457 PF00400 0.417
TRG_Pf-PMV_PEXEL_1 178 182 PF00026 0.467
TRG_Pf-PMV_PEXEL_1 386 390 PF00026 0.378

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PDD3 Leptomonas seymouri 25% 86%
A0A0N1PEF0 Leptomonas seymouri 68% 97%
A0A0S4IUZ2 Bodo saltans 34% 82%
A0A0S4JJU2 Bodo saltans 39% 95%
A0A1X0P2S1 Trypanosomatidae 29% 83%
A0A1X0P4V9 Trypanosomatidae 46% 100%
A0A3S5H744 Leishmania donovani 27% 88%
A0A3S5H808 Leishmania donovani 82% 100%
A0A3S7WZX1 Leishmania donovani 23% 100%
A0A422NGS3 Trypanosoma rangeli 32% 78%
A0A422P1B1 Trypanosoma rangeli 45% 100%
A2Q0Z1 Equus caballus 22% 100%
A4H9P0 Leishmania braziliensis 26% 100%
A4I253 Leishmania infantum 23% 100%
A4IC10 Leishmania infantum 82% 100%
A5A8V7 Sus scrofa 25% 100%
C9ZXL9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 87%
C9ZYJ2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 44% 100%
D0A590 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 89%
D0A8Z2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 25% 100%
E9AFU8 Leishmania major 81% 100%
E9AGQ5 Leishmania infantum 27% 88%
E9ARS1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 26% 88%
E9AYA3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 25% 100%
E9B700 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%
F4HQD4 Arabidopsis thaliana 26% 87%
F4JMJ1 Arabidopsis thaliana 26% 84%
O59838 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 25% 100%
O74225 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 26% 100%
O88600 Rattus norvegicus 26% 86%
O95757 Homo sapiens 26% 86%
O97125 Drosophila melanogaster 24% 100%
P08418 Schistosoma mansoni 23% 100%
P0CB32 Bos taurus 25% 100%
P0DMV8 Homo sapiens 24% 100%
P0DMV9 Homo sapiens 24% 100%
P0DMW0 Rattus norvegicus 24% 100%
P0DMW1 Rattus norvegicus 24% 100%
P11142 Homo sapiens 22% 100%
P16627 Mus musculus 25% 100%
P17879 Mus musculus 24% 100%
P19120 Bos taurus 22% 100%
P19378 Cricetulus griseus 23% 100%
P20030 Trypanosoma brucei brucei 25% 100%
P32589 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 100%
P32590 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 24% 100%
P34930 Sus scrofa 24% 100%
P34931 Homo sapiens 24% 100%
P34932 Homo sapiens 26% 86%
P36415 Dictyostelium discoideum 25% 100%
P41827 Anopheles albimanus 24% 100%
P47773 Ictalurus punctatus 22% 100%
P55063 Rattus norvegicus 25% 100%
P59769 Aspergillus awamori 24% 100%
P63017 Mus musculus 22% 100%
P63018 Rattus norvegicus 22% 100%
P78695 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) 24% 100%
P83616 Aspergillus niger 24% 100%
P83617 Aspergillus kawachii 24% 100%
Q01PM8 Solibacter usitatus (strain Ellin6076) 25% 100%
Q05036 Caenorhabditis elegans 25% 93%
Q06068 Strongylocentrotus purpuratus 27% 81%
Q0VA61 Xenopus tropicalis 30% 100%
Q24789 Echinococcus granulosus 23% 100%
Q27965 Bos taurus 24% 100%
Q27975 Bos taurus 24% 100%
Q2TFN9 Canis lupus familiaris 27% 86%
Q4L6T0 Staphylococcus haemolyticus (strain JCSC1435) 23% 100%
Q4Q970 Leishmania major 24% 100%
Q4QDQ2 Leishmania major 26% 100%
Q4R888 Macaca fascicularis 24% 100%
Q4U0F3 Bos mutus grunniens 24% 100%
Q54BE0 Dictyostelium discoideum 25% 100%
Q566I3 Xenopus laevis 31% 100%
Q5NVM9 Pongo abelii 22% 100%
Q5R7D3 Pongo abelii 24% 100%
Q5RDM4 Pongo abelii 26% 86%
Q5ZLK7 Gallus gallus 28% 72%
Q60432 Cricetulus griseus 30% 72%
Q61316 Mus musculus 28% 86%
Q61696 Mus musculus 24% 100%
Q63617 Rattus norvegicus 30% 72%
Q6FJI3 Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) 23% 100%
Q6L590 Oryza sativa subsp. japonica 23% 100%
Q6S4N2 Sus scrofa 24% 100%
Q6TMK3 Dictyostelium discoideum 23% 94%
Q71U34 Saguinus oedipus 22% 100%
Q74ZJ0 Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) 25% 100%
Q7YQC6 Canis lupus familiaris 24% 100%
Q7ZUW2 Danio rerio 29% 74%
Q875V0 Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630) 25% 100%
Q90473 Danio rerio 23% 100%
Q94738 Mesocentrotus franciscanus 27% 82%
Q96VB9 Candida albicans (strain SC5314 / ATCC MYA-2876) 25% 100%
Q9GSU7 Drosophila simulans 24% 100%
Q9JKR6 Mus musculus 30% 72%
Q9N1U2 Saguinus oedipus 24% 100%
Q9S7C0 Arabidopsis thaliana 26% 87%
Q9SAB1 Arabidopsis thaliana 24% 95%
Q9Y4L1 Homo sapiens 31% 72%
V5ARL4 Trypanosoma cruzi 45% 100%
V5DD81 Trypanosoma cruzi 31% 89%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS