Coiled-coil domain-containing protein 86

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HND1_LEIBR

TriTrypDb:

LbrM.34.4620 , LBRM2903_340056700

Length:

114


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	8
GO:0043226	organelle	2	9
GO:0043227	membrane-bounded organelle	3	8
GO:0043229	intracellular organelle	3	9
GO:0043231	intracellular membrane-bounded organelle	4	8
GO:0110165	cellular anatomical entity	1	9
GO:0005730	nucleolus	5	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1

A4HND1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HND1


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	102	104	PF00675	0.260
CLV_NRD_NRD_1	67	69	PF00675	0.293
CLV_NRD_NRD_1	73	75	PF00675	0.283
CLV_NRD_NRD_1	94	96	PF00675	0.298
CLV_PCSK_KEX2_1	102	104	PF00082	0.404
CLV_PCSK_KEX2_1	62	64	PF00082	0.341
CLV_PCSK_PC1ET2_1	62	64	PF00082	0.289
DOC_CYCLIN_yClb5_NLxxxL_5	45	53	PF00134	0.292
DOC_USP7_MATH_1	25	29	PF00917	0.311
DOC_USP7_UBL2_3	36	40	PF12436	0.295
DOC_USP7_UBL2_3	92	96	PF12436	0.285
DOC_WW_Pin1_4	95	100	PF00397	0.271
LIG_14-3-3_CanoR_1	26	33	PF00244	0.332
LIG_BIR_II_1	1	5	PF00653	0.688
MOD_CDK_SPK_2	95	100	PF00069	0.271
MOD_CDK_SPxxK_3	95	102	PF00069	0.271
MOD_CK1_1	24	30	PF00069	0.193
MOD_GlcNHglycan	23	26	PF01048	0.193
MOD_GlcNHglycan	27	30	PF01048	0.185
MOD_GSK3_1	21	28	PF00069	0.321
MOD_N-GLC_1	47	52	PF02516	0.363
MOD_PIKK_1	47	53	PF00454	0.404
MOD_PKA_2	25	31	PF00069	0.269
MOD_PKB_1	45	53	PF00069	0.271
MOD_ProDKin_1	95	101	PF00069	0.271
MOD_SUMO_for_1	2	5	PF00179	0.643
MOD_SUMO_for_1	53	56	PF00179	0.335
MOD_SUMO_for_1	88	91	PF00179	0.404
MOD_SUMO_rev_2	55	64	PF00179	0.289
MOD_SUMO_rev_2	77	83	PF00179	0.311
TRG_Pf-PMV_PEXEL_1	47	51	PF00026	0.367


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMV4	Leptomonas seymouri	80%	100%
A0A0S4JUA2	Bodo saltans	64%	100%
A0A1X0P578	Trypanosomatidae	60%	100%
A0A3R7NTL4	Trypanosoma rangeli	56%	100%
A0A3S7X9Z5	Leishmania donovani	90%	100%
A4IC03	Leishmania infantum	90%	100%
C9ZYK2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	58%	70%
E9AFU1	Leishmania major	89%	100%
E9B6Z3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%