LeishMANIAdb
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zf-3CxxC domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
zf-3CxxC domain-containing protein
Gene product:
Zinc-binding domain containing protein, putative
Species:
Leishmania braziliensis
UniProt:
A4HNA6_LEIBR
TriTrypDb:
LbrM.34.4350 , LBRM2903_340053600
Length:
114

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HNA6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HNA6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 97 99 PF00675 0.657
CLV_PCSK_KEX2_1 24 26 PF00082 0.357
CLV_PCSK_KEX2_1 88 90 PF00082 0.741
CLV_PCSK_PC1ET2_1 24 26 PF00082 0.492
CLV_PCSK_PC1ET2_1 88 90 PF00082 0.749
DEG_Nend_Nbox_1 1 3 PF02207 0.569
DOC_CKS1_1 16 21 PF01111 0.547
DOC_MAPK_gen_1 9 17 PF00069 0.630
DOC_MAPK_MEF2A_6 3 10 PF00069 0.538
DOC_MAPK_NFAT4_5 3 11 PF00069 0.540
DOC_PP1_RVXF_1 11 18 PF00149 0.581
DOC_PP4_FxxP_1 17 20 PF00568 0.550
DOC_USP7_UBL2_3 24 28 PF12436 0.492
DOC_WW_Pin1_4 15 20 PF00397 0.588
DOC_WW_Pin1_4 80 85 PF00397 0.632
LIG_14-3-3_CanoR_1 3 7 PF00244 0.630
LIG_14-3-3_CanoR_1 36 45 PF00244 0.528
LIG_DCNL_PONY_1 1 4 PF03556 0.650
LIG_FHA_1 3 9 PF00498 0.471
LIG_FHA_1 47 53 PF00498 0.525
LIG_NRBOX 3 9 PF00104 0.636
LIG_SH2_STAT5 69 72 PF00017 0.496
LIG_SH3_3 67 73 PF00018 0.561
MOD_CK1_1 80 86 PF00069 0.482
MOD_CK1_1 93 99 PF00069 0.726
MOD_CK2_1 91 97 PF00069 0.669
MOD_GSK3_1 73 80 PF00069 0.502
MOD_GSK3_1 89 96 PF00069 0.661
MOD_N-GLC_2 79 81 PF02516 0.456
MOD_NEK2_1 100 105 PF00069 0.611
MOD_NEK2_1 2 7 PF00069 0.588
MOD_NEK2_2 73 78 PF00069 0.603
MOD_PIKK_1 46 52 PF00454 0.371
MOD_PKA_2 100 106 PF00069 0.602
MOD_PKA_2 2 8 PF00069 0.654
MOD_Plk_1 73 79 PF00069 0.598
MOD_Plk_4 2 8 PF00069 0.661
MOD_Plk_4 73 79 PF00069 0.564
MOD_ProDKin_1 15 21 PF00069 0.580
MOD_ProDKin_1 80 86 PF00069 0.633
MOD_SUMO_rev_2 92 100 PF00179 0.720
TRG_ER_diArg_1 8 11 PF00400 0.582

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I3J4 Leptomonas seymouri 77% 99%
A0A0S4JPM7 Bodo saltans 60% 100%
A0A3Q8IJH3 Leishmania donovani 89% 100%
A4IBX7 Leishmania infantum 90% 100%
C9ZYN0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 73% 100%
E9AFR4 Leishmania major 93% 100%
E9B6W7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS