LeishMANIAdb
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Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase domain-containing protein
Gene product:
kinetoplastid kinetochore protein 3, putative
Species:
Leishmania braziliensis
UniProt:
A4HN76_LEIBR
TriTrypDb:
LbrM.34.4040 , LBRM2903_340049900
Length:
1276

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Cellular components
Term Name Level Count
GO:0000776 kinetochore 3 1
GO:0043226 organelle 2 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0099080 supramolecular complex 2 1
GO:0110165 cellular anatomical entity 1 2
GO:0016020 membrane 2 1

Expansion

Sequence features

A4HN76
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HN76

Function

Biological processes
Term Name Level Count
GO:0006468 protein phosphorylation 5 8
GO:0006793 phosphorus metabolic process 3 8
GO:0006796 phosphate-containing compound metabolic process 4 8
GO:0006807 nitrogen compound metabolic process 2 8
GO:0008152 metabolic process 1 8
GO:0009987 cellular process 1 8
GO:0016310 phosphorylation 5 8
GO:0019538 protein metabolic process 3 8
GO:0036211 protein modification process 4 8
GO:0043170 macromolecule metabolic process 3 8
GO:0043412 macromolecule modification 4 8
GO:0044237 cellular metabolic process 2 8
GO:0044238 primary metabolic process 2 8
GO:0071704 organic substance metabolic process 2 8
GO:1901564 organonitrogen compound metabolic process 3 8
GO:0007059 chromosome segregation 2 1
GO:0008283 cell population proliferation 2 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 8
GO:0003824 catalytic activity 1 8
GO:0004672 protein kinase activity 3 8
GO:0005488 binding 1 8
GO:0005524 ATP binding 5 8
GO:0016301 kinase activity 4 8
GO:0016740 transferase activity 2 8
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 8
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 8
GO:0017076 purine nucleotide binding 4 8
GO:0030554 adenyl nucleotide binding 5 8
GO:0032553 ribonucleotide binding 3 8
GO:0032555 purine ribonucleotide binding 4 8
GO:0032559 adenyl ribonucleotide binding 5 8
GO:0035639 purine ribonucleoside triphosphate binding 4 8
GO:0036094 small molecule binding 2 8
GO:0043167 ion binding 2 8
GO:0043168 anion binding 3 8
GO:0097159 organic cyclic compound binding 2 8
GO:0097367 carbohydrate derivative binding 2 8
GO:0140096 catalytic activity, acting on a protein 2 8
GO:1901265 nucleoside phosphate binding 3 8
GO:1901363 heterocyclic compound binding 2 8
GO:0004674 protein serine/threonine kinase activity 4 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1054 1058 PF00656 0.628
CLV_C14_Caspase3-7 1138 1142 PF00656 0.566
CLV_C14_Caspase3-7 412 416 PF00656 0.585
CLV_C14_Caspase3-7 577 581 PF00656 0.508
CLV_NRD_NRD_1 1043 1045 PF00675 0.675
CLV_NRD_NRD_1 1241 1243 PF00675 0.457
CLV_NRD_NRD_1 15 17 PF00675 0.368
CLV_NRD_NRD_1 297 299 PF00675 0.322
CLV_NRD_NRD_1 347 349 PF00675 0.450
CLV_NRD_NRD_1 462 464 PF00675 0.607
CLV_NRD_NRD_1 484 486 PF00675 0.629
CLV_NRD_NRD_1 490 492 PF00675 0.615
CLV_NRD_NRD_1 514 516 PF00675 0.719
CLV_NRD_NRD_1 641 643 PF00675 0.806
CLV_NRD_NRD_1 708 710 PF00675 0.823
CLV_NRD_NRD_1 757 759 PF00675 0.572
CLV_NRD_NRD_1 934 936 PF00675 0.644
CLV_NRD_NRD_1 963 965 PF00675 0.668
CLV_PCSK_FUR_1 641 645 PF00082 0.543
CLV_PCSK_KEX2_1 1043 1045 PF00082 0.675
CLV_PCSK_KEX2_1 210 212 PF00082 0.351
CLV_PCSK_KEX2_1 297 299 PF00082 0.324
CLV_PCSK_KEX2_1 346 348 PF00082 0.545
CLV_PCSK_KEX2_1 464 466 PF00082 0.616
CLV_PCSK_KEX2_1 484 486 PF00082 0.502
CLV_PCSK_KEX2_1 490 492 PF00082 0.620
CLV_PCSK_KEX2_1 514 516 PF00082 0.724
CLV_PCSK_KEX2_1 641 643 PF00082 0.809
CLV_PCSK_KEX2_1 708 710 PF00082 0.823
CLV_PCSK_KEX2_1 735 737 PF00082 0.658
CLV_PCSK_KEX2_1 757 759 PF00082 0.524
CLV_PCSK_KEX2_1 933 935 PF00082 0.644
CLV_PCSK_KEX2_1 962 964 PF00082 0.670
CLV_PCSK_KEX2_1 998 1000 PF00082 0.518
CLV_PCSK_PC1ET2_1 210 212 PF00082 0.241
CLV_PCSK_PC1ET2_1 464 466 PF00082 0.609
CLV_PCSK_PC1ET2_1 643 645 PF00082 0.657
CLV_PCSK_PC1ET2_1 735 737 PF00082 0.600
CLV_PCSK_PC1ET2_1 998 1000 PF00082 0.518
CLV_PCSK_SKI1_1 1056 1060 PF00082 0.551
CLV_PCSK_SKI1_1 1126 1130 PF00082 0.472
CLV_PCSK_SKI1_1 1158 1162 PF00082 0.508
CLV_PCSK_SKI1_1 1242 1246 PF00082 0.429
CLV_PCSK_SKI1_1 155 159 PF00082 0.292
CLV_PCSK_SKI1_1 17 21 PF00082 0.402
CLV_PCSK_SKI1_1 490 494 PF00082 0.680
CLV_PCSK_SKI1_1 557 561 PF00082 0.536
CLV_PCSK_SKI1_1 60 64 PF00082 0.292
CLV_PCSK_SKI1_1 649 653 PF00082 0.564
CLV_PCSK_SKI1_1 739 743 PF00082 0.580
CLV_PCSK_SKI1_1 806 810 PF00082 0.519
CLV_PCSK_SKI1_1 88 92 PF00082 0.319
CLV_PCSK_SKI1_1 954 958 PF00082 0.791
CLV_Separin_Metazoa 807 811 PF03568 0.390
CLV_Separin_Metazoa 930 934 PF03568 0.698
DEG_APCC_DBOX_1 432 440 PF00400 0.619
DEG_APCC_DBOX_1 73 81 PF00400 0.292
DEG_APCC_DBOX_1 756 764 PF00400 0.554
DEG_Nend_Nbox_1 1 3 PF02207 0.444
DEG_SCF_FBW7_1 422 428 PF00400 0.557
DEG_SPOP_SBC_1 396 400 PF00917 0.570
DEG_SPOP_SBC_1 425 429 PF00917 0.557
DOC_CKS1_1 1050 1055 PF01111 0.638
DOC_CKS1_1 240 245 PF01111 0.280
DOC_CKS1_1 422 427 PF01111 0.557
DOC_CYCLIN_RxL_1 82 95 PF00134 0.292
DOC_MAPK_gen_1 1150 1159 PF00069 0.543
DOC_MAPK_gen_1 1176 1186 PF00069 0.550
DOC_MAPK_gen_1 14 22 PF00069 0.438
DOC_MAPK_gen_1 208 216 PF00069 0.351
DOC_MAPK_gen_1 463 474 PF00069 0.609
DOC_MAPK_gen_1 69 79 PF00069 0.292
DOC_MAPK_gen_1 735 746 PF00069 0.555
DOC_MAPK_gen_1 757 765 PF00069 0.572
DOC_MAPK_gen_1 804 811 PF00069 0.538
DOC_MAPK_HePTP_8 1149 1161 PF00069 0.537
DOC_MAPK_HePTP_8 732 744 PF00069 0.460
DOC_MAPK_MEF2A_6 101 110 PF00069 0.292
DOC_MAPK_MEF2A_6 1150 1159 PF00069 0.543
DOC_MAPK_MEF2A_6 14 22 PF00069 0.360
DOC_MAPK_MEF2A_6 208 216 PF00069 0.351
DOC_MAPK_MEF2A_6 467 476 PF00069 0.610
DOC_MAPK_MEF2A_6 557 564 PF00069 0.536
DOC_MAPK_MEF2A_6 735 744 PF00069 0.532
DOC_MAPK_NFAT4_5 739 747 PF00069 0.585
DOC_PP1_RVXF_1 1156 1162 PF00149 0.514
DOC_PP1_RVXF_1 169 176 PF00149 0.292
DOC_PP1_RVXF_1 835 842 PF00149 0.578
DOC_PP2B_LxvP_1 112 115 PF13499 0.292
DOC_PP2B_LxvP_1 182 185 PF13499 0.351
DOC_PP2B_LxvP_1 89 92 PF13499 0.292
DOC_PP2B_LxvP_1 983 986 PF13499 0.471
DOC_PP2B_PxIxI_1 985 991 PF00149 0.601
DOC_PP4_FxxP_1 196 199 PF00568 0.292
DOC_PP4_FxxP_1 842 845 PF00568 0.542
DOC_USP7_MATH_1 1024 1028 PF00917 0.667
DOC_USP7_MATH_1 178 182 PF00917 0.355
DOC_USP7_MATH_1 236 240 PF00917 0.301
DOC_USP7_MATH_1 24 28 PF00917 0.543
DOC_USP7_MATH_1 265 269 PF00917 0.390
DOC_USP7_MATH_1 397 401 PF00917 0.689
DOC_USP7_MATH_1 409 413 PF00917 0.721
DOC_USP7_MATH_1 432 436 PF00917 0.688
DOC_USP7_MATH_1 549 553 PF00917 0.699
DOC_USP7_MATH_1 637 641 PF00917 0.613
DOC_USP7_MATH_1 697 701 PF00917 0.626
DOC_USP7_MATH_2 270 276 PF00917 0.215
DOC_USP7_MATH_2 328 334 PF00917 0.280
DOC_WW_Pin1_4 1049 1054 PF00397 0.588
DOC_WW_Pin1_4 195 200 PF00397 0.351
DOC_WW_Pin1_4 239 244 PF00397 0.349
DOC_WW_Pin1_4 392 397 PF00397 0.656
DOC_WW_Pin1_4 421 426 PF00397 0.731
DOC_WW_Pin1_4 547 552 PF00397 0.713
DOC_WW_Pin1_4 592 597 PF00397 0.682
DOC_WW_Pin1_4 650 655 PF00397 0.778
DOC_WW_Pin1_4 687 692 PF00397 0.622
DOC_WW_Pin1_4 695 700 PF00397 0.652
DOC_WW_Pin1_4 943 948 PF00397 0.593
LIG_14-3-3_CanoR_1 1191 1201 PF00244 0.579
LIG_14-3-3_CanoR_1 1213 1220 PF00244 0.507
LIG_14-3-3_CanoR_1 126 135 PF00244 0.351
LIG_14-3-3_CanoR_1 211 215 PF00244 0.289
LIG_14-3-3_CanoR_1 281 286 PF00244 0.365
LIG_14-3-3_CanoR_1 514 520 PF00244 0.655
LIG_14-3-3_CanoR_1 52 61 PF00244 0.376
LIG_14-3-3_CanoR_1 703 708 PF00244 0.570
LIG_14-3-3_CanoR_1 709 718 PF00244 0.599
LIG_14-3-3_CanoR_1 757 766 PF00244 0.544
LIG_14-3-3_CanoR_1 785 791 PF00244 0.557
LIG_14-3-3_CanoR_1 906 910 PF00244 0.618
LIG_Actin_WH2_2 11 28 PF00022 0.397
LIG_Actin_WH2_2 156 173 PF00022 0.292
LIG_APCC_ABBA_1 1070 1075 PF00400 0.534
LIG_BRCT_BRCA1_1 1117 1121 PF00533 0.537
LIG_BRCT_BRCA1_1 1240 1244 PF00533 0.520
LIG_deltaCOP1_diTrp_1 1030 1036 PF00928 0.655
LIG_deltaCOP1_diTrp_1 1063 1071 PF00928 0.519
LIG_deltaCOP1_diTrp_1 1234 1244 PF00928 0.447
LIG_deltaCOP1_diTrp_1 219 228 PF00928 0.331
LIG_deltaCOP1_diTrp_1 303 306 PF00928 0.292
LIG_deltaCOP1_diTrp_1 767 775 PF00928 0.539
LIG_FHA_1 100 106 PF00498 0.351
LIG_FHA_1 1103 1109 PF00498 0.495
LIG_FHA_1 1144 1150 PF00498 0.580
LIG_FHA_1 1181 1187 PF00498 0.555
LIG_FHA_1 1257 1263 PF00498 0.444
LIG_FHA_1 383 389 PF00498 0.545
LIG_FHA_1 514 520 PF00498 0.532
LIG_FHA_1 593 599 PF00498 0.641
LIG_FHA_2 1050 1056 PF00498 0.580
LIG_FHA_2 1082 1088 PF00498 0.734
LIG_FHA_2 115 121 PF00498 0.292
LIG_FHA_2 324 330 PF00498 0.361
LIG_FHA_2 397 403 PF00498 0.549
LIG_FHA_2 572 578 PF00498 0.578
LIG_FHA_2 585 591 PF00498 0.570
LIG_FHA_2 776 782 PF00498 0.503
LIG_IBAR_NPY_1 235 237 PF08397 0.292
LIG_IRF3_LxIS_1 59 66 PF10401 0.351
LIG_LIR_Apic_2 1185 1190 PF02991 0.614
LIG_LIR_Apic_2 193 199 PF02991 0.340
LIG_LIR_Apic_2 303 307 PF02991 0.296
LIG_LIR_Gen_1 1091 1102 PF02991 0.581
LIG_LIR_Gen_1 1118 1129 PF02991 0.537
LIG_LIR_Gen_1 1199 1209 PF02991 0.490
LIG_LIR_Gen_1 145 153 PF02991 0.243
LIG_LIR_Gen_1 826 834 PF02991 0.468
LIG_LIR_Nem_3 1030 1036 PF02991 0.655
LIG_LIR_Nem_3 1091 1097 PF02991 0.590
LIG_LIR_Nem_3 1118 1124 PF02991 0.535
LIG_LIR_Nem_3 1125 1131 PF02991 0.539
LIG_LIR_Nem_3 1199 1204 PF02991 0.502
LIG_LIR_Nem_3 46 50 PF02991 0.292
LIG_LIR_Nem_3 55 61 PF02991 0.292
LIG_LIR_Nem_3 826 830 PF02991 0.447
LIG_LIR_Nem_3 853 858 PF02991 0.496
LIG_LIR_Nem_3 95 99 PF02991 0.314
LIG_LYPXL_yS_3 237 240 PF13949 0.241
LIG_LYPXL_yS_3 58 61 PF13949 0.292
LIG_NRBOX 117 123 PF00104 0.295
LIG_PCNA_yPIPBox_3 1205 1219 PF02747 0.531
LIG_PDZ_Class_2 1271 1276 PF00595 0.573
LIG_Pex14_1 1064 1068 PF04695 0.514
LIG_PTB_Apo_2 1227 1234 PF02174 0.501
LIG_PTB_Apo_2 158 165 PF02174 0.292
LIG_PTB_Phospho_1 1227 1233 PF10480 0.504
LIG_RPA_C_Fungi 1208 1220 PF08784 0.525
LIG_RPA_C_Fungi 480 492 PF08784 0.682
LIG_RPA_C_Fungi 753 765 PF08784 0.550
LIG_SH2_CRK 1094 1098 PF00017 0.573
LIG_SH2_CRK 1187 1191 PF00017 0.613
LIG_SH2_CRK 1248 1252 PF00017 0.547
LIG_SH2_CRK 51 55 PF00017 0.292
LIG_SH2_CRK 818 822 PF00017 0.420
LIG_SH2_SRC 816 819 PF00017 0.518
LIG_SH2_STAP1 1094 1098 PF00017 0.573
LIG_SH2_STAP1 1170 1174 PF00017 0.493
LIG_SH2_STAP1 1233 1237 PF00017 0.426
LIG_SH2_STAP1 456 460 PF00017 0.692
LIG_SH2_STAP1 786 790 PF00017 0.581
LIG_SH2_STAT3 1098 1101 PF00017 0.507
LIG_SH2_STAT3 858 861 PF00017 0.462
LIG_SH2_STAT5 1069 1072 PF00017 0.590
LIG_SH2_STAT5 1203 1206 PF00017 0.482
LIG_SH2_STAT5 146 149 PF00017 0.399
LIG_SH2_STAT5 855 858 PF00017 0.594
LIG_SH2_STAT5 890 893 PF00017 0.495
LIG_SH3_2 1029 1034 PF14604 0.617
LIG_SH3_2 929 934 PF14604 0.692
LIG_SH3_3 1006 1012 PF00018 0.649
LIG_SH3_3 1026 1032 PF00018 0.550
LIG_SH3_3 264 270 PF00018 0.215
LIG_SH3_3 322 328 PF00018 0.399
LIG_SH3_3 419 425 PF00018 0.559
LIG_SH3_3 493 499 PF00018 0.693
LIG_SH3_3 828 834 PF00018 0.528
LIG_SH3_3 866 872 PF00018 0.397
LIG_SH3_3 926 932 PF00018 0.684
LIG_Sin3_3 762 769 PF02671 0.547
LIG_SUMO_SIM_anti_2 104 109 PF11976 0.292
LIG_SUMO_SIM_anti_2 471 476 PF11976 0.629
LIG_SUMO_SIM_anti_2 613 619 PF11976 0.667
LIG_SUMO_SIM_anti_2 76 81 PF11976 0.292
LIG_SUMO_SIM_par_1 761 767 PF11976 0.548
LIG_TRAF2_1 1052 1055 PF00917 0.579
LIG_TRAF2_1 1086 1089 PF00917 0.636
LIG_TRAF2_1 376 379 PF00917 0.567
LIG_TRAF2_1 778 781 PF00917 0.502
LIG_TRAF2_2 243 248 PF00917 0.215
LIG_TRFH_1 1068 1072 PF08558 0.517
LIG_TRFH_1 1260 1264 PF08558 0.436
LIG_TYR_ITIM 1246 1251 PF00017 0.535
LIG_TYR_ITSM 47 54 PF00017 0.292
LIG_WRC_WIRS_1 1271 1276 PF05994 0.578
LIG_WRC_WIRS_1 772 777 PF05994 0.552
LIG_WRPW_2 1033 1036 PF00400 0.634
MOD_CDC14_SPxK_1 550 553 PF00782 0.607
MOD_CDC14_SPxK_1 946 949 PF00782 0.539
MOD_CDK_SPxK_1 547 553 PF00069 0.619
MOD_CDK_SPxK_1 943 949 PF00069 0.545
MOD_CDK_SPxxK_3 1049 1056 PF00069 0.581
MOD_CDK_SPxxK_3 426 433 PF00069 0.578
MOD_CDK_SPxxK_3 650 657 PF00069 0.521
MOD_CK1_1 1112 1118 PF00069 0.455
MOD_CK1_1 1192 1198 PF00069 0.574
MOD_CK1_1 195 201 PF00069 0.355
MOD_CK1_1 229 235 PF00069 0.292
MOD_CK1_1 239 245 PF00069 0.292
MOD_CK1_1 251 257 PF00069 0.208
MOD_CK1_1 27 33 PF00069 0.551
MOD_CK1_1 333 339 PF00069 0.359
MOD_CK1_1 395 401 PF00069 0.696
MOD_CK1_1 416 422 PF00069 0.736
MOD_CK1_1 46 52 PF00069 0.183
MOD_CK1_1 497 503 PF00069 0.615
MOD_CK1_1 585 591 PF00069 0.749
MOD_CK1_1 592 598 PF00069 0.704
MOD_CK1_1 670 676 PF00069 0.667
MOD_CK1_1 682 688 PF00069 0.796
MOD_CK1_1 690 696 PF00069 0.491
MOD_CK1_1 698 704 PF00069 0.601
MOD_CK1_1 713 719 PF00069 0.586
MOD_CK2_1 1024 1030 PF00069 0.657
MOD_CK2_1 1049 1055 PF00069 0.590
MOD_CK2_1 1119 1125 PF00069 0.479
MOD_CK2_1 126 132 PF00069 0.388
MOD_CK2_1 272 278 PF00069 0.215
MOD_CK2_1 29 35 PF00069 0.338
MOD_CK2_1 323 329 PF00069 0.310
MOD_CK2_1 364 370 PF00069 0.533
MOD_CK2_1 396 402 PF00069 0.545
MOD_CK2_1 571 577 PF00069 0.579
MOD_CK2_1 584 590 PF00069 0.533
MOD_CK2_1 775 781 PF00069 0.503
MOD_CK2_1 970 976 PF00069 0.552
MOD_Cter_Amidation 812 815 PF01082 0.429
MOD_GlcNHglycan 1081 1084 PF01048 0.692
MOD_GlcNHglycan 1117 1120 PF01048 0.486
MOD_GlcNHglycan 1191 1194 PF01048 0.591
MOD_GlcNHglycan 1215 1218 PF01048 0.489
MOD_GlcNHglycan 251 254 PF01048 0.324
MOD_GlcNHglycan 26 29 PF01048 0.542
MOD_GlcNHglycan 267 270 PF01048 0.189
MOD_GlcNHglycan 274 277 PF01048 0.248
MOD_GlcNHglycan 378 383 PF01048 0.544
MOD_GlcNHglycan 418 421 PF01048 0.715
MOD_GlcNHglycan 487 490 PF01048 0.704
MOD_GlcNHglycan 496 499 PF01048 0.705
MOD_GlcNHglycan 508 511 PF01048 0.726
MOD_GlcNHglycan 526 529 PF01048 0.693
MOD_GlcNHglycan 534 537 PF01048 0.571
MOD_GlcNHglycan 54 57 PF01048 0.266
MOD_GlcNHglycan 610 613 PF01048 0.700
MOD_GlcNHglycan 637 640 PF01048 0.690
MOD_GlcNHglycan 663 666 PF01048 0.653
MOD_GlcNHglycan 675 678 PF01048 0.746
MOD_GlcNHglycan 692 695 PF01048 0.630
MOD_GlcNHglycan 713 716 PF01048 0.613
MOD_GlcNHglycan 719 722 PF01048 0.660
MOD_GlcNHglycan 760 763 PF01048 0.511
MOD_GlcNHglycan 796 800 PF01048 0.530
MOD_GlcNHglycan 896 899 PF01048 0.625
MOD_GSK3_1 1108 1115 PF00069 0.513
MOD_GSK3_1 1139 1146 PF00069 0.565
MOD_GSK3_1 121 128 PF00069 0.351
MOD_GSK3_1 319 326 PF00069 0.224
MOD_GSK3_1 378 385 PF00069 0.556
MOD_GSK3_1 388 395 PF00069 0.592
MOD_GSK3_1 409 416 PF00069 0.766
MOD_GSK3_1 421 428 PF00069 0.699
MOD_GSK3_1 494 501 PF00069 0.637
MOD_GSK3_1 502 509 PF00069 0.600
MOD_GSK3_1 515 522 PF00069 0.638
MOD_GSK3_1 524 531 PF00069 0.684
MOD_GSK3_1 567 574 PF00069 0.572
MOD_GSK3_1 584 591 PF00069 0.533
MOD_GSK3_1 667 674 PF00069 0.687
MOD_GSK3_1 679 686 PF00069 0.560
MOD_GSK3_1 695 702 PF00069 0.569
MOD_GSK3_1 709 716 PF00069 0.590
MOD_GSK3_1 771 778 PF00069 0.561
MOD_GSK3_1 78 85 PF00069 0.396
MOD_GSK3_1 890 897 PF00069 0.643
MOD_LATS_1 633 639 PF00433 0.693
MOD_LATS_1 756 762 PF00433 0.553
MOD_LATS_1 961 967 PF00433 0.535
MOD_N-GLC_1 1211 1216 PF02516 0.534
MOD_N-GLC_1 413 418 PF02516 0.591
MOD_N-GLC_1 943 948 PF02516 0.665
MOD_N-GLC_1 99 104 PF02516 0.351
MOD_N-GLC_2 873 875 PF02516 0.539
MOD_NEK2_1 121 126 PF00069 0.294
MOD_NEK2_1 1218 1223 PF00069 0.467
MOD_NEK2_1 1238 1243 PF00069 0.348
MOD_NEK2_1 319 324 PF00069 0.367
MOD_NEK2_1 388 393 PF00069 0.566
MOD_NEK2_1 519 524 PF00069 0.760
MOD_NEK2_1 582 587 PF00069 0.627
MOD_NEK2_1 608 613 PF00069 0.671
MOD_NEK2_1 63 68 PF00069 0.351
MOD_NEK2_1 660 665 PF00069 0.788
MOD_NEK2_1 742 747 PF00069 0.458
MOD_NEK2_1 771 776 PF00069 0.539
MOD_NEK2_1 881 886 PF00069 0.565
MOD_NEK2_2 1182 1187 PF00069 0.562
MOD_NEK2_2 178 183 PF00069 0.357
MOD_NEK2_2 432 437 PF00069 0.691
MOD_PIKK_1 229 235 PF00454 0.292
MOD_PIKK_1 310 316 PF00454 0.357
MOD_PIKK_1 679 685 PF00454 0.572
MOD_PIKK_1 884 890 PF00454 0.567
MOD_PIKK_1 963 969 PF00454 0.537
MOD_PK_1 210 216 PF00069 0.351
MOD_PK_1 281 287 PF00069 0.215
MOD_PK_1 470 476 PF00069 0.609
MOD_PK_1 610 616 PF00069 0.664
MOD_PKA_1 210 216 PF00069 0.351
MOD_PKA_1 643 649 PF00069 0.804
MOD_PKA_1 963 969 PF00069 0.537
MOD_PKA_2 125 131 PF00069 0.292
MOD_PKA_2 210 216 PF00069 0.292
MOD_PKA_2 330 336 PF00069 0.384
MOD_PKA_2 432 438 PF00069 0.625
MOD_PKA_2 458 464 PF00069 0.601
MOD_PKA_2 483 489 PF00069 0.685
MOD_PKA_2 513 519 PF00069 0.544
MOD_PKA_2 643 649 PF00069 0.574
MOD_PKA_2 660 666 PF00069 0.658
MOD_PKA_2 756 762 PF00069 0.654
MOD_PKA_2 775 781 PF00069 0.473
MOD_PKA_2 784 790 PF00069 0.569
MOD_PKA_2 905 911 PF00069 0.689
MOD_PKA_2 963 969 PF00069 0.537
MOD_PKA_2 986 992 PF00069 0.588
MOD_PKB_1 642 650 PF00069 0.620
MOD_Plk_1 1112 1118 PF00069 0.419
MOD_Plk_1 1211 1217 PF00069 0.463
MOD_Plk_1 413 419 PF00069 0.556
MOD_Plk_1 470 476 PF00069 0.609
MOD_Plk_1 644 650 PF00069 0.829
MOD_Plk_1 742 748 PF00069 0.477
MOD_Plk_1 922 928 PF00069 0.542
MOD_Plk_1 970 976 PF00069 0.618
MOD_Plk_2-3 29 35 PF00069 0.338
MOD_Plk_2-3 330 336 PF00069 0.215
MOD_Plk_4 1144 1150 PF00069 0.580
MOD_Plk_4 1182 1188 PF00069 0.618
MOD_Plk_4 142 148 PF00069 0.343
MOD_Plk_4 192 198 PF00069 0.321
MOD_Plk_4 319 325 PF00069 0.377
MOD_Plk_4 333 339 PF00069 0.277
MOD_Plk_4 384 390 PF00069 0.520
MOD_Plk_4 46 52 PF00069 0.292
MOD_Plk_4 621 627 PF00069 0.537
MOD_ProDKin_1 1049 1055 PF00069 0.585
MOD_ProDKin_1 195 201 PF00069 0.351
MOD_ProDKin_1 239 245 PF00069 0.349
MOD_ProDKin_1 392 398 PF00069 0.657
MOD_ProDKin_1 421 427 PF00069 0.731
MOD_ProDKin_1 547 553 PF00069 0.712
MOD_ProDKin_1 592 598 PF00069 0.684
MOD_ProDKin_1 650 656 PF00069 0.777
MOD_ProDKin_1 687 693 PF00069 0.625
MOD_ProDKin_1 695 701 PF00069 0.652
MOD_ProDKin_1 943 949 PF00069 0.594
MOD_SUMO_rev_2 150 159 PF00179 0.351
MOD_SUMO_rev_2 313 319 PF00179 0.351
TRG_DiLeu_BaEn_1 1055 1060 PF01217 0.555
TRG_DiLeu_BaEn_1 767 772 PF01217 0.537
TRG_DiLeu_BaEn_2 1124 1130 PF01217 0.544
TRG_DiLeu_BaEn_2 1239 1245 PF01217 0.451
TRG_DiLeu_BaEn_3 1091 1097 PF01217 0.595
TRG_DiLeu_BaLyEn_6 291 296 PF01217 0.351
TRG_DiLeu_BaLyEn_6 85 90 PF01217 0.351
TRG_ENDOCYTIC_2 1094 1097 PF00928 0.571
TRG_ENDOCYTIC_2 1248 1251 PF00928 0.550
TRG_ENDOCYTIC_2 1271 1274 PF00928 0.499
TRG_ENDOCYTIC_2 146 149 PF00928 0.231
TRG_ENDOCYTIC_2 237 240 PF00928 0.241
TRG_ENDOCYTIC_2 51 54 PF00928 0.292
TRG_ENDOCYTIC_2 58 61 PF00928 0.292
TRG_ENDOCYTIC_2 818 821 PF00928 0.427
TRG_ENDOCYTIC_2 827 830 PF00928 0.439
TRG_ER_diArg_1 296 298 PF00400 0.292
TRG_ER_diArg_1 345 348 PF00400 0.420
TRG_ER_diArg_1 641 644 PF00400 0.794
TRG_ER_diArg_1 707 709 PF00400 0.679
TRG_ER_diArg_1 71 74 PF00400 0.215
TRG_ER_diArg_1 932 935 PF00400 0.691
TRG_ER_diArg_1 962 964 PF00400 0.670
TRG_NLS_MonoExtC_3 462 467 PF00514 0.663
TRG_NLS_MonoExtN_4 463 468 PF00514 0.666
TRG_Pf-PMV_PEXEL_1 848 853 PF00026 0.431

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P4X3 Leptomonas seymouri 61% 92%
A0A3Q8IFG0 Leishmania donovani 79% 99%
A4IBU4 Leishmania infantum 79% 99%
E9AFN1 Leishmania major 78% 99%
E9B6T4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 98%
V5BTA3 Trypanosoma cruzi 45% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS