LeishMANIAdb
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FCP1 homology domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
FCP1 homology domain-containing protein
Gene product:
NLI interacting factor-like phosphatase, putative
Species:
Leishmania braziliensis
UniProt:
A4HN21_LEIBR
TriTrypDb:
LbrM.34.3450 , LBRM2903_340043600 *
Length:
506

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HN21
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HN21

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0003824 catalytic activity 1 1
GO:0004721 phosphoprotein phosphatase activity 3 1
GO:0016787 hydrolase activity 2 1
GO:0016788 hydrolase activity, acting on ester bonds 3 1
GO:0016791 phosphatase activity 5 1
GO:0042578 phosphoric ester hydrolase activity 4 1
GO:0140096 catalytic activity, acting on a protein 2 1
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 125 127 PF00675 0.792
CLV_NRD_NRD_1 383 385 PF00675 0.433
CLV_NRD_NRD_1 390 392 PF00675 0.351
CLV_NRD_NRD_1 411 413 PF00675 0.678
CLV_NRD_NRD_1 81 83 PF00675 0.678
CLV_PCSK_KEX2_1 111 113 PF00082 0.792
CLV_PCSK_KEX2_1 125 127 PF00082 0.606
CLV_PCSK_KEX2_1 383 385 PF00082 0.433
CLV_PCSK_KEX2_1 410 412 PF00082 0.665
CLV_PCSK_PC1ET2_1 111 113 PF00082 0.792
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IIK2 Leishmania donovani 59% 90%
A4IBP7 Leishmania infantum 59% 90%
E9AFH6 Leishmania major 59% 100%
E9B6N1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 62% 93%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS