Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4HN09_LEIBR

TriTrypDb:

LbrM.34.3330 , LBRM2903_340042100

Length:

189

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HN09

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HN09

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	114	116	PF00675	0.616
CLV_PCSK_KEX2_1	114	116	PF00082	0.623
CLV_PCSK_SKI1_1	91	95	PF00082	0.539
DEG_Nend_UBRbox_4	1	3	PF02207	0.499
DOC_CKS1_1	75	80	PF01111	0.515
DOC_MAPK_DCC_7	171	179	PF00069	0.342
DOC_MAPK_MEF2A_6	171	179	PF00069	0.342
DOC_PP4_FxxP_1	10	13	PF00568	0.594
DOC_PP4_FxxP_1	186	189	PF00568	0.397
DOC_PP4_FxxP_1	75	78	PF00568	0.739
DOC_USP7_MATH_1	43	47	PF00917	0.622
DOC_USP7_MATH_1	48	52	PF00917	0.588
DOC_USP7_MATH_1	6	10	PF00917	0.618
DOC_USP7_MATH_1	69	73	PF00917	0.537
DOC_USP7_MATH_1	97	101	PF00917	0.604
DOC_WW_Pin1_4	56	61	PF00397	0.732
DOC_WW_Pin1_4	74	79	PF00397	0.469
LIG_14-3-3_CanoR_1	165	174	PF00244	0.430
LIG_BRCT_BRCA1_1	175	179	PF00533	0.334
LIG_BRCT_BRCA1_1	35	39	PF00533	0.604
LIG_BRCT_BRCA1_1	71	75	PF00533	0.666
LIG_Clathr_ClatBox_1	178	182	PF01394	0.422
LIG_FHA_1	24	30	PF00498	0.628
LIG_FHA_1	93	99	PF00498	0.651
LIG_FHA_2	78	84	PF00498	0.643
LIG_LIR_Apic_2	183	189	PF02991	0.392
LIG_LIR_Apic_2	72	78	PF02991	0.740
LIG_LIR_Apic_2	9	13	PF02991	0.593
LIG_LIR_Gen_1	131	141	PF02991	0.453
LIG_LIR_Nem_3	131	137	PF02991	0.469
LIG_LIR_Nem_3	140	146	PF02991	0.464
LIG_Pex14_2	10	14	PF04695	0.595
LIG_SH2_STAT3	34	37	PF00017	0.484
LIG_Sin3_3	104	111	PF02671	0.435
LIG_TRAF2_1	180	183	PF00917	0.512
MOD_CDK_SPK_2	74	79	PF00069	0.514
MOD_CK1_1	120	126	PF00069	0.411
MOD_CK1_1	22	28	PF00069	0.625
MOD_CK2_1	177	183	PF00069	0.490
MOD_CK2_1	77	83	PF00069	0.636
MOD_GlcNHglycan	21	24	PF01048	0.589
MOD_GlcNHglycan	99	102	PF01048	0.527
MOD_GSK3_1	128	135	PF00069	0.450
MOD_GSK3_1	173	180	PF00069	0.595
MOD_GSK3_1	19	26	PF00069	0.673
MOD_GSK3_1	48	55	PF00069	0.497
MOD_GSK3_1	69	76	PF00069	0.658
MOD_GSK3_1	87	94	PF00069	0.516
MOD_NEK2_1	128	133	PF00069	0.441
MOD_NEK2_1	14	19	PF00069	0.617
MOD_NEK2_1	33	38	PF00069	0.630
MOD_NEK2_2	6	11	PF00069	0.606
MOD_PIKK_1	144	150	PF00454	0.459
MOD_PIKK_1	33	39	PF00454	0.631
MOD_Plk_4	14	20	PF00069	0.471
MOD_Plk_4	173	179	PF00069	0.482
MOD_ProDKin_1	56	62	PF00069	0.733
MOD_ProDKin_1	74	80	PF00069	0.469
TRG_Pf-PMV_PEXEL_1	115	119	PF00026	0.576
TRG_Pf-PMV_PEXEL_1	165	169	PF00026	0.371

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IIJ1	Leishmania donovani	68%	100%
A4IBN2	Leishmania infantum	68%	100%
E9AFG6	Leishmania major	71%	100%
E9B6M1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	68%	100%