40S ribosomal protein S6

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HMZ4_LEIBR

TriTrypDb:

LbrM.34.3180 , LBRM2903_340040500

Length:

188

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HMZ4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HMZ4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	9	13	PF00656	0.508
CLV_NRD_NRD_1	163	165	PF00675	0.523
CLV_NRD_NRD_1	167	169	PF00675	0.523
CLV_NRD_NRD_1	180	182	PF00675	0.580
CLV_NRD_NRD_1	184	186	PF00675	0.583
CLV_NRD_NRD_1	32	34	PF00675	0.503
CLV_NRD_NRD_1	66	68	PF00675	0.674
CLV_PCSK_KEX2_1	154	156	PF00082	0.504
CLV_PCSK_KEX2_1	180	182	PF00082	0.580
CLV_PCSK_KEX2_1	184	186	PF00082	0.583
CLV_PCSK_KEX2_1	32	34	PF00082	0.503
CLV_PCSK_KEX2_1	65	67	PF00082	0.485
CLV_PCSK_PC1ET2_1	154	156	PF00082	0.504
CLV_PCSK_PC7_1	150	156	PF00082	0.540
CLV_PCSK_PC7_1	180	186	PF00082	0.584
CLV_PCSK_SKI1_1	86	90	PF00082	0.445
DEG_SPOP_SBC_1	125	129	PF00917	0.631
DOC_USP7_MATH_1	125	129	PF00917	0.720
DOC_USP7_MATH_1	139	143	PF00917	0.782
DOC_USP7_MATH_1	159	163	PF00917	0.511
DOC_USP7_UBL2_3	157	161	PF12436	0.568
DOC_USP7_UBL2_3	165	169	PF12436	0.444
DOC_USP7_UBL2_3	49	53	PF12436	0.512
DOC_USP7_UBL2_3	89	93	PF12436	0.529
DOC_WW_Pin1_4	126	131	PF00397	0.623
LIG_14-3-3_CanoR_1	109	114	PF00244	0.512
LIG_14-3-3_CanoR_1	150	158	PF00244	0.456
LIG_14-3-3_CanoR_1	75	81	PF00244	0.521
LIG_BIR_II_1	1	5	PF00653	0.626
LIG_BIR_III_3	1	5	PF00653	0.486
LIG_deltaCOP1_diTrp_1	7	17	PF00928	0.497
LIG_FHA_1	1	7	PF00498	0.634
LIG_FHA_2	75	81	PF00498	0.561
LIG_LIR_Gen_1	15	25	PF02991	0.454
LIG_LIR_Nem_3	15	21	PF02991	0.449
LIG_NRP_CendR_1	185	188	PF00754	0.600
LIG_Pex14_2	17	21	PF04695	0.446
LIG_SH2_CRK	179	183	PF00017	0.578
LIG_Sin3_3	69	76	PF02671	0.432
LIG_TYR_ITIM	177	182	PF00017	0.568
LIG_WRC_WIRS_1	110	115	PF05994	0.568
MOD_CDK_SPxxK_3	126	133	PF00069	0.608
MOD_CK1_1	111	117	PF00069	0.682
MOD_CK1_1	128	134	PF00069	0.563
MOD_CK1_1	149	155	PF00069	0.603
MOD_CK1_1	74	80	PF00069	0.522
MOD_CK2_1	128	134	PF00069	0.546
MOD_CK2_1	139	145	PF00069	0.502
MOD_CK2_1	57	63	PF00069	0.466
MOD_CK2_1	74	80	PF00069	0.501
MOD_GlcNHglycan	104	107	PF01048	0.585
MOD_GlcNHglycan	115	118	PF01048	0.602
MOD_GlcNHglycan	141	144	PF01048	0.624
MOD_GlcNHglycan	161	164	PF01048	0.439
MOD_GlcNHglycan	58	62	PF01048	0.479
MOD_GSK3_1	109	116	PF00069	0.555
MOD_GSK3_1	120	127	PF00069	0.613
MOD_GSK3_1	129	136	PF00069	0.528
MOD_GSK3_1	19	26	PF00069	0.479
MOD_GSK3_1	98	105	PF00069	0.671
MOD_LATS_1	107	113	PF00433	0.511
MOD_NEK2_1	113	118	PF00069	0.582
MOD_PIKK_1	149	155	PF00454	0.465
MOD_PIKK_1	43	49	PF00454	0.544
MOD_PKA_1	180	186	PF00069	0.495
MOD_PKA_2	108	114	PF00069	0.509
MOD_PKA_2	139	145	PF00069	0.688
MOD_PKA_2	149	155	PF00069	0.503
MOD_PKA_2	180	186	PF00069	0.517
MOD_PKA_2	74	80	PF00069	0.517
MOD_Plk_1	19	25	PF00069	0.518
MOD_ProDKin_1	126	132	PF00069	0.619
TRG_ENDOCYTIC_2	179	182	PF00928	0.579
TRG_ER_diArg_1	179	181	PF00400	0.580
TRG_ER_diArg_1	184	187	PF00400	0.590
TRG_ER_diArg_1	65	67	PF00400	0.478
TRG_NLS_Bipartite_1	32	52	PF00514	0.406

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDT8	Leptomonas seymouri	49%	100%
A0A3S7X9J2	Leishmania donovani	67%	100%
A4IBL8	Leishmania infantum	66%	100%
E9AFF1	Leishmania major	69%	100%
E9B6K6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	70%	100%