CCDC92 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HMS8_LEIBR

TriTrypDb:

LbrM.34.2500 , LBRM2903_340032700

Length:

218

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HMS8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HMS8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	4	8	PF00656	0.458
CLV_NRD_NRD_1	126	128	PF00675	0.680
CLV_NRD_NRD_1	195	197	PF00675	0.677
CLV_NRD_NRD_1	201	203	PF00675	0.687
CLV_NRD_NRD_1	25	27	PF00675	0.451
CLV_NRD_NRD_1	60	62	PF00675	0.542
CLV_NRD_NRD_1	94	96	PF00675	0.692
CLV_PCSK_KEX2_1	126	128	PF00082	0.677
CLV_PCSK_KEX2_1	190	192	PF00082	0.780
CLV_PCSK_KEX2_1	194	196	PF00082	0.757
CLV_PCSK_KEX2_1	200	202	PF00082	0.689
CLV_PCSK_KEX2_1	25	27	PF00082	0.451
CLV_PCSK_KEX2_1	94	96	PF00082	0.692
CLV_PCSK_PC1ET2_1	190	192	PF00082	0.804
CLV_PCSK_PC7_1	191	197	PF00082	0.742
CLV_PCSK_SKI1_1	169	173	PF00082	0.693
CLV_PCSK_SKI1_1	17	21	PF00082	0.474
CLV_PCSK_SKI1_1	28	32	PF00082	0.433
CLV_PCSK_SKI1_1	78	82	PF00082	0.511
CLV_Separin_Metazoa	12	16	PF03568	0.471
DOC_CKS1_1	79	84	PF01111	0.663
DOC_CYCLIN_RxL_1	164	176	PF00134	0.786
DOC_PP1_RVXF_1	15	21	PF00149	0.480
DOC_PP4_FxxP_1	132	135	PF00568	0.549
DOC_USP7_MATH_1	128	132	PF00917	0.732
DOC_USP7_MATH_1	8	12	PF00917	0.534
DOC_WW_Pin1_4	118	123	PF00397	0.686
DOC_WW_Pin1_4	126	131	PF00397	0.704
DOC_WW_Pin1_4	157	162	PF00397	0.645
DOC_WW_Pin1_4	78	83	PF00397	0.662
DOC_WW_Pin1_4	88	93	PF00397	0.707
LIG_14-3-3_CanoR_1	115	121	PF00244	0.690
LIG_14-3-3_CanoR_1	148	153	PF00244	0.592
LIG_14-3-3_CanoR_1	173	180	PF00244	0.733
LIG_14-3-3_CanoR_1	194	199	PF00244	0.700
LIG_14-3-3_CanoR_1	200	209	PF00244	0.674
LIG_14-3-3_CanoR_1	95	101	PF00244	0.541
LIG_BIR_II_1	1	5	PF00653	0.512
LIG_BRCT_BRCA1_1	128	132	PF00533	0.544
LIG_DLG_GKlike_1	148	155	PF00625	0.522
LIG_FHA_1	179	185	PF00498	0.722
LIG_FHA_1	201	207	PF00498	0.724
LIG_LIR_Apic_2	129	135	PF02991	0.549
LIG_SH3_1	164	170	PF00018	0.534
LIG_SH3_2	79	84	PF14604	0.663
LIG_SH3_3	164	170	PF00018	0.596
LIG_SH3_3	76	82	PF00018	0.626
LIG_SH3_3	98	104	PF00018	0.738
LIG_SUMO_SIM_anti_2	32	39	PF11976	0.629
LIG_SUMO_SIM_anti_2	54	60	PF11976	0.532
MOD_CDC14_SPxK_1	91	94	PF00782	0.705
MOD_CDK_SPxK_1	78	84	PF00069	0.664
MOD_CDK_SPxK_1	88	94	PF00069	0.710
MOD_CDK_SPxxK_3	157	164	PF00069	0.534
MOD_CDK_SPxxK_3	88	95	PF00069	0.711
MOD_CK1_1	118	124	PF00069	0.634
MOD_CK1_1	142	148	PF00069	0.693
MOD_CK1_1	151	157	PF00069	0.665
MOD_CK1_1	204	210	PF00069	0.793
MOD_CK1_1	36	42	PF00069	0.550
MOD_CK1_1	54	60	PF00069	0.532
MOD_CK2_1	84	90	PF00069	0.756
MOD_Cter_Amidation	188	191	PF01082	0.554
MOD_Cter_Amidation	59	62	PF01082	0.489
MOD_DYRK1A_RPxSP_1	78	82	PF00069	0.692
MOD_GlcNHglycan	122	125	PF01048	0.744
MOD_GlcNHglycan	141	144	PF01048	0.697
MOD_GlcNHglycan	176	179	PF01048	0.789
MOD_GSK3_1	116	123	PF00069	0.675
MOD_GSK3_1	135	142	PF00069	0.761
MOD_GSK3_1	144	151	PF00069	0.705
MOD_GSK3_1	153	160	PF00069	0.643
MOD_GSK3_1	174	181	PF00069	0.788
MOD_GSK3_1	196	203	PF00069	0.768
MOD_GSK3_1	84	91	PF00069	0.704
MOD_N-GLC_1	116	121	PF02516	0.557
MOD_N-GLC_1	174	179	PF02516	0.722
MOD_N-GLC_1	184	189	PF02516	0.745
MOD_NEK2_1	139	144	PF00069	0.543
MOD_NEK2_1	155	160	PF00069	0.715
MOD_NEK2_1	171	176	PF00069	0.712
MOD_PK_1	202	208	PF00069	0.723
MOD_PK_1	84	90	PF00069	0.785
MOD_PKA_1	194	200	PF00069	0.720
MOD_PKA_1	201	207	PF00069	0.734
MOD_PKA_2	194	200	PF00069	0.727
MOD_PKA_2	201	207	PF00069	0.755
MOD_PKA_2	33	39	PF00069	0.500
MOD_PKB_1	113	121	PF00069	0.618
MOD_PKB_1	194	202	PF00069	0.733
MOD_Plk_1	116	122	PF00069	0.555
MOD_Plk_4	33	39	PF00069	0.558
MOD_Plk_4	51	57	PF00069	0.538
MOD_Plk_4	96	102	PF00069	0.639
MOD_ProDKin_1	118	124	PF00069	0.686
MOD_ProDKin_1	126	132	PF00069	0.703
MOD_ProDKin_1	157	163	PF00069	0.647
MOD_ProDKin_1	78	84	PF00069	0.664
MOD_ProDKin_1	88	94	PF00069	0.710
TRG_DiLeu_BaEn_3	32	38	PF01217	0.377
TRG_DiLeu_BaLyEn_6	167	172	PF01217	0.720
TRG_ER_diArg_1	125	127	PF00400	0.800
TRG_ER_diArg_1	193	196	PF00400	0.703
TRG_ER_diArg_1	200	202	PF00400	0.663
TRG_ER_diArg_1	24	26	PF00400	0.458
TRG_ER_diArg_1	93	95	PF00400	0.684

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P940	Leptomonas seymouri	58%	100%
A0A3S7X9C5	Leishmania donovani	75%	100%
A4IBG6	Leishmania infantum	75%	100%
C9ZZ99	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	100%
E9AF80	Leishmania major	74%	100%
E9B6D6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	100%