Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Eukaryotic protein of unknown function (DUF1764), putative

Species:

Leishmania braziliensis

UniProt:

A4HMR0_LEIBR

TriTrypDb:

LbrM.34.2310 , LBRM2903_340030600

Length:

198

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HMR0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HMR0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	161	163	PF00675	0.428
CLV_NRD_NRD_1	70	72	PF00675	0.556
CLV_PCSK_KEX2_1	161	163	PF00082	0.452
CLV_PCSK_SKI1_1	135	139	PF00082	0.548
DEG_Nend_UBRbox_1	1	4	PF02207	0.729
DEG_SPOP_SBC_1	146	150	PF00917	0.634
DEG_SPOP_SBC_1	28	32	PF00917	0.716
DEG_SPOP_SBC_1	33	37	PF00917	0.482
DEG_SPOP_SBC_1	92	96	PF00917	0.691
DOC_USP7_MATH_1	114	118	PF00917	0.597
DOC_USP7_MATH_1	146	150	PF00917	0.675
DOC_USP7_MATH_1	153	157	PF00917	0.499
DOC_USP7_MATH_1	33	37	PF00917	0.717
DOC_USP7_MATH_1	7	11	PF00917	0.728
DOC_WW_Pin1_4	11	16	PF00397	0.736
DOC_WW_Pin1_4	149	154	PF00397	0.745
DOC_WW_Pin1_4	184	189	PF00397	0.370
DOC_WW_Pin1_4	57	62	PF00397	0.545
LIG_14-3-3_CanoR_1	167	172	PF00244	0.343
LIG_14-3-3_CanoR_1	8	15	PF00244	0.749
LIG_DLG_GKlike_1	167	174	PF00625	0.402
LIG_FHA_1	12	18	PF00498	0.779
LIG_FHA_1	23	29	PF00498	0.670
LIG_FHA_1	35	41	PF00498	0.676
LIG_LIR_Apic_2	108	114	PF02991	0.564
LIG_LRP6_Inhibitor_1	45	51	PF00058	0.419
LIG_Pex14_2	126	130	PF04695	0.595
LIG_RPA_C_Fungi	157	169	PF08784	0.253
LIG_SH3_3	185	191	PF00018	0.335
LIG_SUMO_SIM_anti_2	41	47	PF11976	0.411
LIG_TRAF2_1	170	173	PF00917	0.374
LIG_UBA3_1	46	54	PF00899	0.562
MOD_CK1_1	145	151	PF00069	0.699
MOD_CK1_1	16	22	PF00069	0.683
MOD_CK1_1	32	38	PF00069	0.729
MOD_CK1_1	93	99	PF00069	0.655
MOD_CK2_1	167	173	PF00069	0.370
MOD_GlcNHglycan	126	129	PF01048	0.591
MOD_GlcNHglycan	144	147	PF01048	0.432
MOD_GlcNHglycan	31	34	PF01048	0.571
MOD_GlcNHglycan	76	79	PF01048	0.687
MOD_GlcNHglycan	86	89	PF01048	0.704
MOD_GlcNHglycan	9	12	PF01048	0.783
MOD_GSK3_1	114	121	PF00069	0.604
MOD_GSK3_1	135	142	PF00069	0.701
MOD_GSK3_1	145	152	PF00069	0.601
MOD_GSK3_1	28	35	PF00069	0.629
MOD_GSK3_1	46	53	PF00069	0.630
MOD_GSK3_1	7	14	PF00069	0.735
MOD_GSK3_1	90	97	PF00069	0.553
MOD_N-GLC_1	135	140	PF02516	0.486
MOD_NEK2_1	126	131	PF00069	0.600
MOD_NEK2_1	46	51	PF00069	0.622
MOD_PK_1	13	19	PF00069	0.552
MOD_PKA_2	7	13	PF00069	0.737
MOD_Plk_1	114	120	PF00069	0.611
MOD_Plk_4	126	132	PF00069	0.577
MOD_ProDKin_1	11	17	PF00069	0.736
MOD_ProDKin_1	149	155	PF00069	0.746
MOD_ProDKin_1	184	190	PF00069	0.370
MOD_ProDKin_1	57	63	PF00069	0.545
TRG_DiLeu_BaEn_3	172	178	PF01217	0.385

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8J3	Leptomonas seymouri	47%	100%
A0A1X0P736	Trypanosomatidae	33%	100%
A0A3S7X9A2	Leishmania donovani	70%	99%
E9AF60	Leishmania major	70%	100%
E9AHW2	Leishmania infantum	70%	100%
E9B6B6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	69%	99%