Putative ER--golgi transport protein gp25L

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ER--golgi transport protein gp25L, putative

Species:

Leishmania braziliensis

UniProt:

A4HMK6_LEIBR

TriTrypDb:

LbrM.34.1760 , LBRM2903_340023900

Length:

216

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 8, no: 2
NetGPI	no	yes: 0, no: 10

Show entries

Cellular components
Term	Name	Level	Count
GO:0005783	endoplasmic reticulum	5	1
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	5	1
GO:0005794	Golgi apparatus	5	1
GO:0016020	membrane	2	11
GO:0030134	COPII-coated ER to Golgi transport vesicle	8	1
GO:0030135	coated vesicle	7	1
GO:0031410	cytoplasmic vesicle	6	1
GO:0031982	vesicle	4	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1

Previous1 2Next

Expansion

Sequence features

A4HMK6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HMK6

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0006886	intracellular protein transport	4	1
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	4	1
GO:0006996	organelle organization	4	1
GO:0007030	Golgi organization	5	1
GO:0008104	protein localization	4	1
GO:0009987	cellular process	1	1
GO:0015031	protein transport	4	1
GO:0016043	cellular component organization	3	1
GO:0016192	vesicle-mediated transport	4	1

Previous1 2 3Next

Could not find GO molecular_function term for this entry.

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	206	208	PF00082	0.231
CLV_PCSK_KEX2_1	212	214	PF00082	0.364
CLV_PCSK_PC1ET2_1	206	208	PF00082	0.232
CLV_PCSK_PC1ET2_1	212	214	PF00082	0.363
CLV_PCSK_SKI1_1	117	121	PF00082	0.503
CLV_PCSK_SKI1_1	203	207	PF00082	0.233
CLV_PCSK_SKI1_1	4	8	PF00082	0.636
CLV_PCSK_SKI1_1	41	45	PF00082	0.508
DEG_APCC_DBOX_1	116	124	PF00400	0.314
DOC_MAPK_gen_1	114	122	PF00069	0.242

Previous1 2 3 4 5…8Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBE2	Leptomonas seymouri	63%	100%
A0A0S4IQL9	Bodo saltans	37%	100%
A0A0S4J7E6	Bodo saltans	24%	98%
A0A0S4JYK0	Bodo saltans	25%	100%
A0A1X0P6V5	Trypanosomatidae	40%	100%
A0A3R7NST9	Trypanosoma rangeli	40%	100%
A0A3S7X951	Leishmania donovani	85%	100%
A0AQ71	Drosophila simulans	25%	100%
A4IB85	Leishmania infantum	84%	100%
A7SXK3	Nematostella vectensis	23%	100%

Previous1 2 3 4 5…10Next