G_PROTEIN_RECEP_F2_4 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HMK5_LEIBR

TriTrypDb:

LbrM.34.1750 , LBRM2903_340023800

Length:

149


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

A4HMK5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HMK5


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	113	117	PF00082	0.384
CLV_PCSK_SKI1_1	89	93	PF00082	0.446
DOC_CKS1_1	141	146	PF01111	0.563
DOC_CKS1_1	43	48	PF01111	0.401
DOC_MAPK_gen_1	33	41	PF00069	0.312
DOC_MAPK_MEF2A_6	35	43	PF00069	0.210
DOC_USP7_UBL2_3	89	93	PF12436	0.595
DOC_WW_Pin1_4	134	139	PF00397	0.671
DOC_WW_Pin1_4	140	145	PF00397	0.609
DOC_WW_Pin1_4	42	47	PF00397	0.372
LIG_14-3-3_CanoR_1	113	119	PF00244	0.511
LIG_14-3-3_CanoR_1	66	71	PF00244	0.543
LIG_FHA_1	107	113	PF00498	0.603
LIG_FHA_1	114	120	PF00498	0.613
LIG_FHA_1	36	42	PF00498	0.310
LIG_FHA_1	43	49	PF00498	0.373
LIG_FHA_1	83	89	PF00498	0.675
LIG_LIR_Gen_1	38	48	PF02991	0.394
LIG_LIR_Nem_3	34	39	PF02991	0.444
LIG_Pex14_1	36	40	PF04695	0.391
LIG_SH2_CRK	52	56	PF00017	0.233
LIG_SH2_PTP2	40	43	PF00017	0.444
LIG_SH2_STAT5	30	33	PF00017	0.562
LIG_SH2_STAT5	40	43	PF00017	0.401
LIG_SH2_STAT5	57	60	PF00017	0.416
LIG_SH3_3	132	138	PF00018	0.742
LIG_SH3_3	21	27	PF00018	0.369
LIG_SH3_3	40	46	PF00018	0.239
LIG_SUMO_SIM_anti_2	137	143	PF11976	0.568
LIG_SUMO_SIM_par_1	137	143	PF11976	0.568
LIG_TYR_ITIM	50	55	PF00017	0.250
LIG_TYR_ITSM	36	43	PF00017	0.361
MOD_CK1_1	137	143	PF00069	0.680
MOD_CK2_1	128	134	PF00069	0.745
MOD_GSK3_1	31	38	PF00069	0.468
MOD_NEK2_1	19	24	PF00069	0.416
MOD_NEK2_1	76	81	PF00069	0.660
MOD_Plk_4	114	120	PF00069	0.662
MOD_Plk_4	66	72	PF00069	0.679
MOD_ProDKin_1	134	140	PF00069	0.670
MOD_ProDKin_1	42	48	PF00069	0.372
MOD_SUMO_for_1	105	108	PF00179	0.662
TRG_ENDOCYTIC_2	40	43	PF00928	0.444
TRG_ENDOCYTIC_2	52	55	PF00928	0.282
TRG_ENDOCYTIC_2	57	60	PF00928	0.402
TRG_ENDOCYTIC_2	61	64	PF00928	0.659


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJI6	Leptomonas seymouri	56%	99%
A0A1X0P639	Trypanosomatidae	41%	100%
A0A3Q8IM56	Leishmania donovani	67%	99%
A4IB84	Leishmania infantum	67%	99%
C9ZZK9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
E9AF05	Leishmania major	66%	100%
E9B661	Leishmania mexicana (strain MHOM/GT/2001/U1103)	72%	99%
V5BHZ7	Trypanosoma cruzi	47%	99%