No signal peptide, but transit signal possible. Localization: Mitochondrial (by feature)
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 11 |
| NetGPI | no | yes: 0, no: 11 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0016020 | membrane | 2 | 11 |
| GO:0110165 | cellular anatomical entity | 1 | 11 |
Related structures:
AlphaFold database: A4HMJ7
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_PCSK_SKI1_1 | 92 | 96 | PF00082 | 0.618 |
| DEG_APCC_DBOX_1 | 16 | 24 | PF00400 | 0.551 |
| DEG_APCC_DBOX_1 | 4 | 12 | PF00400 | 0.649 |
| DEG_Nend_Nbox_1 | 1 | 3 | PF02207 | 0.679 |
| DEG_ODPH_VHL_1 | 8 | 20 | PF01847 | 0.611 |
| DOC_CDC14_PxL_1 | 6 | 14 | PF14671 | 0.684 |
| DOC_CKS1_1 | 108 | 113 | PF01111 | 0.556 |
| DOC_PP4_FxxP_1 | 117 | 120 | PF00568 | 0.529 |
| DOC_USP7_MATH_1 | 33 | 37 | PF00917 | 0.620 |
| DOC_USP7_MATH_1 | 50 | 54 | PF00917 | 0.344 |
| DOC_WW_Pin1_4 | 107 | 112 | PF00397 | 0.464 |
| DOC_WW_Pin1_4 | 118 | 123 | PF00397 | 0.408 |
| DOC_WW_Pin1_4 | 92 | 97 | PF00397 | 0.412 |
| LIG_14-3-3_CanoR_1 | 102 | 107 | PF00244 | 0.522 |
| LIG_BRCT_BRCA1_1 | 52 | 56 | PF00533 | 0.449 |
| LIG_deltaCOP1_diTrp_1 | 124 | 128 | PF00928 | 0.407 |
| LIG_deltaCOP1_diTrp_1 | 38 | 44 | PF00928 | 0.608 |
| LIG_DLG_GKlike_1 | 102 | 110 | PF00625 | 0.546 |
| LIG_FHA_1 | 62 | 68 | PF00498 | 0.437 |
| LIG_FHA_1 | 79 | 85 | PF00498 | 0.406 |
| LIG_FHA_2 | 114 | 120 | PF00498 | 0.448 |
| LIG_HP1_1 | 50 | 54 | PF01393 | 0.223 |
| LIG_LIR_Apic_2 | 116 | 120 | PF02991 | 0.446 |
| LIG_LIR_Apic_2 | 4 | 10 | PF02991 | 0.592 |
| LIG_LIR_Gen_1 | 85 | 94 | PF02991 | 0.420 |
| LIG_LIR_Nem_3 | 124 | 128 | PF02991 | 0.407 |
| LIG_LIR_Nem_3 | 25 | 30 | PF02991 | 0.626 |
| LIG_LIR_Nem_3 | 38 | 43 | PF02991 | 0.588 |
| LIG_LIR_Nem_3 | 53 | 59 | PF02991 | 0.297 |
| LIG_LIR_Nem_3 | 70 | 74 | PF02991 | 0.372 |
| LIG_LIR_Nem_3 | 85 | 89 | PF02991 | 0.412 |
| LIG_LYPXL_S_1 | 48 | 52 | PF13949 | 0.358 |
| LIG_LYPXL_yS_3 | 49 | 52 | PF13949 | 0.476 |
| LIG_Pex14_1 | 40 | 44 | PF04695 | 0.607 |
| LIG_SH2_CRK | 27 | 31 | PF00017 | 0.619 |
| LIG_SH2_SRC | 86 | 89 | PF00017 | 0.407 |
| LIG_SH2_STAT3 | 134 | 137 | PF00017 | 0.453 |
| LIG_SH2_STAT5 | 134 | 137 | PF00017 | 0.453 |
| LIG_SH2_STAT5 | 7 | 10 | PF00017 | 0.589 |
| LIG_SH3_3 | 108 | 114 | PF00018 | 0.452 |
| LIG_SUMO_SIM_par_1 | 50 | 55 | PF11976 | 0.489 |
| LIG_SUMO_SIM_par_1 | 76 | 82 | PF11976 | 0.327 |
| LIG_TYR_ITIM | 84 | 89 | PF00017 | 0.402 |
| LIG_TYR_ITSM | 23 | 30 | PF00017 | 0.623 |
| LIG_WRC_WIRS_1 | 103 | 108 | PF05994 | 0.546 |
| MOD_CK1_1 | 107 | 113 | PF00069 | 0.555 |
| MOD_CK1_1 | 13 | 19 | PF00069 | 0.574 |
| MOD_GSK3_1 | 22 | 29 | PF00069 | 0.653 |
| MOD_GSK3_1 | 78 | 85 | PF00069 | 0.412 |
| MOD_NEK2_1 | 1 | 6 | PF00069 | 0.651 |
| MOD_PKB_1 | 102 | 110 | PF00069 | 0.546 |
| MOD_Plk_2-3 | 82 | 88 | PF00069 | 0.418 |
| MOD_ProDKin_1 | 107 | 113 | PF00069 | 0.462 |
| MOD_ProDKin_1 | 118 | 124 | PF00069 | 0.407 |
| MOD_ProDKin_1 | 92 | 98 | PF00069 | 0.412 |
| MOD_SUMO_for_1 | 23 | 26 | PF00179 | 0.614 |
| MOD_SUMO_rev_2 | 124 | 132 | PF00179 | 0.407 |
| TRG_DiLeu_BaEn_2 | 37 | 43 | PF01217 | 0.609 |
| TRG_ENDOCYTIC_2 | 27 | 30 | PF00928 | 0.632 |
| TRG_ENDOCYTIC_2 | 49 | 52 | PF00928 | 0.476 |
| TRG_ENDOCYTIC_2 | 74 | 77 | PF00928 | 0.390 |
| TRG_ENDOCYTIC_2 | 86 | 89 | PF00928 | 0.407 |
| TRG_ER_diArg_1 | 101 | 104 | PF00400 | 0.354 |
| TRG_ER_diArg_1 | 2 | 5 | PF00400 | 0.712 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P4D9 | Leptomonas seymouri | 80% | 100% |
| A0A0S4KFM7 | Bodo saltans | 73% | 99% |
| A0A1X0P629 | Trypanosomatidae | 72% | 100% |
| A0A3R7M0Z8 | Trypanosoma rangeli | 69% | 100% |
| A0A3S7X9C1 | Leishmania donovani | 94% | 100% |
| A4IB76 | Leishmania infantum | 94% | 100% |
| C9ZZK0 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 77% | 100% |
| E9AEZ7 | Leishmania major | 91% | 100% |
| E9B653 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 90% | 100% |
| V5D9I0 | Trypanosoma cruzi | 72% | 100% |