ANF_receptor domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4HMJ6_LEIBR

TriTrypDb:

LbrM.34.1660 , LBRM2903_340022900

Length:

463

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 3, no: 1
NetGPI	no	yes: 0, no: 4

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

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Expansion

Sequence features

A4HMJ6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HMJ6

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0008194	UDP-glycosyltransferase activity	4	2
GO:0016740	transferase activity	2	2
GO:0016757	glycosyltransferase activity	3	2

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	102	104	PF00675	0.452
CLV_NRD_NRD_1	159	161	PF00675	0.629
CLV_NRD_NRD_1	292	294	PF00675	0.516
CLV_NRD_NRD_1	392	394	PF00675	0.506
CLV_PCSK_FUR_1	290	294	PF00082	0.502
CLV_PCSK_KEX2_1	104	106	PF00082	0.465
CLV_PCSK_KEX2_1	159	161	PF00082	0.645
CLV_PCSK_KEX2_1	292	294	PF00082	0.516
CLV_PCSK_KEX2_1	392	394	PF00082	0.514
CLV_PCSK_PC1ET2_1	104	106	PF00082	0.465

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PB88	Leptomonas seymouri	38%	96%
A0A1X0P5U1	Trypanosomatidae	25%	92%
A0A3S5IRM5	Trypanosoma rangeli	24%	95%

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