Ubiquitinyl hydrolase 1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ubiquitin hydrolase, putative

Species:

Leishmania braziliensis

UniProt:

A4HMJ4_LEIBR

TriTrypDb:

LbrM.34.1640 , LBRM2903_340022700

Length:

1164

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005829	cytosol	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4HMJ4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HMJ4

Function

Biological processes
Term	Name	Level	Count
GO:0006508	proteolysis	4	11
GO:0006511	ubiquitin-dependent protein catabolic process	7	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0009056	catabolic process	2	11
GO:0009057	macromolecule catabolic process	4	11
GO:0009987	cellular process	1	11
GO:0016579	protein deubiquitination	6	11
GO:0019538	protein metabolic process	3	11
GO:0019941	modification-dependent protein catabolic process	6	11
GO:0036211	protein modification process	4	11
GO:0043170	macromolecule metabolic process	3	11
GO:0043412	macromolecule modification	4	11
GO:0043632	modification-dependent macromolecule catabolic process	5	11
GO:0044237	cellular metabolic process	2	11
GO:0044238	primary metabolic process	2	11
GO:0044248	cellular catabolic process	3	11
GO:0044260	obsolete cellular macromolecule metabolic process	3	11
GO:0044265	obsolete cellular macromolecule catabolic process	4	11
GO:0051603	proteolysis involved in protein catabolic process	5	11
GO:0070646	protein modification by small protein removal	5	11
GO:0070647	protein modification by small protein conjugation or removal	5	11
GO:0071704	organic substance metabolic process	2	11
GO:1901564	organonitrogen compound metabolic process	3	11
GO:1901575	organic substance catabolic process	3	11
GO:0031647	regulation of protein stability	3	1
GO:0065007	biological regulation	1	1
GO:0065008	regulation of biological quality	2	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	11
GO:0004843	cysteine-type deubiquitinase activity	5	11
GO:0008233	peptidase activity	3	11
GO:0008234	cysteine-type peptidase activity	4	11
GO:0016787	hydrolase activity	2	11
GO:0019783	ubiquitin-like protein peptidase activity	4	11
GO:0101005	deubiquitinase activity	5	11
GO:0140096	catalytic activity, acting on a protein	2	11
GO:0004175	endopeptidase activity	4	1
GO:0004197	cysteine-type endopeptidase activity	5	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	319	323	PF00656	0.308
CLV_NRD_NRD_1	1055	1057	PF00675	0.334
CLV_NRD_NRD_1	1081	1083	PF00675	0.297
CLV_NRD_NRD_1	19	21	PF00675	0.575
CLV_NRD_NRD_1	504	506	PF00675	0.586
CLV_NRD_NRD_1	536	538	PF00675	0.574
CLV_NRD_NRD_1	738	740	PF00675	0.504
CLV_PCSK_FUR_1	1053	1057	PF00082	0.334
CLV_PCSK_KEX2_1	1055	1057	PF00082	0.334
CLV_PCSK_KEX2_1	1081	1083	PF00082	0.307
CLV_PCSK_KEX2_1	1151	1153	PF00082	0.563
CLV_PCSK_KEX2_1	1155	1157	PF00082	0.568
CLV_PCSK_KEX2_1	504	506	PF00082	0.547
CLV_PCSK_KEX2_1	536	538	PF00082	0.574
CLV_PCSK_KEX2_1	738	740	PF00082	0.640
CLV_PCSK_KEX2_1	977	979	PF00082	0.358
CLV_PCSK_PC1ET2_1	1151	1153	PF00082	0.563
CLV_PCSK_PC1ET2_1	1155	1157	PF00082	0.568
CLV_PCSK_PC1ET2_1	977	979	PF00082	0.358
CLV_PCSK_SKI1_1	1138	1142	PF00082	0.265
CLV_PCSK_SKI1_1	20	24	PF00082	0.433
CLV_PCSK_SKI1_1	241	245	PF00082	0.380
CLV_PCSK_SKI1_1	270	274	PF00082	0.421
CLV_PCSK_SKI1_1	370	374	PF00082	0.410
CLV_PCSK_SKI1_1	439	443	PF00082	0.308
CLV_PCSK_SKI1_1	504	508	PF00082	0.503
CLV_PCSK_SKI1_1	537	541	PF00082	0.538
CLV_PCSK_SKI1_1	550	554	PF00082	0.323
CLV_PCSK_SKI1_1	603	607	PF00082	0.498
CLV_PCSK_SKI1_1	650	654	PF00082	0.468
CLV_PCSK_SKI1_1	9	13	PF00082	0.405
DEG_APCC_DBOX_1	240	248	PF00400	0.380
DEG_APCC_DBOX_1	866	874	PF00400	0.468
DEG_APCC_KENBOX_2	263	267	PF00400	0.452
DEG_Nend_Nbox_1	1	3	PF02207	0.385
DEG_SPOP_SBC_1	110	114	PF00917	0.653
DOC_CDC14_PxL_1	682	690	PF14671	0.573
DOC_CKS1_1	432	437	PF01111	0.199
DOC_CKS1_1	616	621	PF01111	0.489
DOC_CKS1_1	773	778	PF01111	0.534
DOC_CYCLIN_RxL_1	17	26	PF00134	0.531
DOC_CYCLIN_RxL_1	237	248	PF00134	0.380
DOC_CYCLIN_RxL_1	546	556	PF00134	0.358
DOC_CYCLIN_RxL_1	597	608	PF00134	0.441
DOC_CYCLIN_yClb5_NLxxxL_5	242	251	PF00134	0.380
DOC_CYCLIN_yCln2_LP_2	643	649	PF00134	0.434
DOC_CYCLIN_yCln2_LP_2	935	941	PF00134	0.558
DOC_MAPK_DCC_7	345	355	PF00069	0.350
DOC_MAPK_gen_1	1081	1087	PF00069	0.393
DOC_MAPK_gen_1	1151	1162	PF00069	0.588
DOC_MAPK_gen_1	345	355	PF00069	0.333
DOC_MAPK_gen_1	594	602	PF00069	0.403
DOC_MAPK_MEF2A_6	1081	1089	PF00069	0.400
DOC_MAPK_MEF2A_6	345	354	PF00069	0.317
DOC_MAPK_MEF2A_6	642	651	PF00069	0.409
DOC_MAPK_MEF2A_6	798	805	PF00069	0.459
DOC_PP1_RVXF_1	515	521	PF00149	0.389
DOC_PP1_RVXF_1	648	654	PF00149	0.442
DOC_PP1_RVXF_1	7	14	PF00149	0.405
DOC_PP1_RVXF_1	842	848	PF00149	0.468
DOC_PP2B_LxvP_1	1029	1032	PF13499	0.475
DOC_PP2B_LxvP_1	873	876	PF13499	0.443
DOC_PP4_FxxP_1	520	523	PF00568	0.414
DOC_USP7_MATH_1	227	231	PF00917	0.452
DOC_USP7_MATH_1	481	485	PF00917	0.594
DOC_USP7_MATH_1	670	674	PF00917	0.500
DOC_USP7_MATH_1	876	880	PF00917	0.562
DOC_USP7_MATH_1	968	972	PF00917	0.482
DOC_USP7_UBL2_3	1151	1155	PF12436	0.606
DOC_USP7_UBL2_3	124	128	PF12436	0.477
DOC_WD40_RPTOR_TOS_1	316	322	PF00400	0.297
DOC_WW_Pin1_4	259	264	PF00397	0.440
DOC_WW_Pin1_4	387	392	PF00397	0.452
DOC_WW_Pin1_4	431	436	PF00397	0.380
DOC_WW_Pin1_4	615	620	PF00397	0.477
DOC_WW_Pin1_4	772	777	PF00397	0.507
DOC_WW_Pin1_4	93	98	PF00397	0.505
DOC_WW_Pin1_4	99	104	PF00397	0.551
LIG_14-3-3_CanoR_1	47	51	PF00244	0.551
LIG_14-3-3_CanoR_1	471	479	PF00244	0.404
LIG_14-3-3_CanoR_1	536	544	PF00244	0.511
LIG_14-3-3_CanoR_1	830	836	PF00244	0.377
LIG_14-3-3_CanoR_1	867	871	PF00244	0.493
LIG_14-3-3_CanoR_1	88	97	PF00244	0.531
LIG_Actin_WH2_2	425	441	PF00022	0.261
LIG_AP2alpha_1	442	446	PF02296	0.452
LIG_APCC_ABBA_1	908	913	PF00400	0.485
LIG_BRCT_BRCA1_1	1062	1066	PF00533	0.507
LIG_BRCT_BRCA1_1	904	908	PF00533	0.456
LIG_Clathr_ClatBox_1	979	983	PF01394	0.534
LIG_deltaCOP1_diTrp_1	989	997	PF00928	0.544
LIG_eIF4E_1	198	204	PF01652	0.327
LIG_eIF4E_1	764	770	PF01652	0.460
LIG_FHA_1	100	106	PF00498	0.600
LIG_FHA_1	151	157	PF00498	0.308
LIG_FHA_1	214	220	PF00498	0.294
LIG_FHA_1	238	244	PF00498	0.308
LIG_FHA_1	271	277	PF00498	0.404
LIG_FHA_1	367	373	PF00498	0.367
LIG_FHA_1	378	384	PF00498	0.317
LIG_FHA_1	470	476	PF00498	0.448
LIG_FHA_1	538	544	PF00498	0.557
LIG_FHA_1	546	552	PF00498	0.425
LIG_FHA_1	619	625	PF00498	0.552
LIG_FHA_1	687	693	PF00498	0.644
LIG_FHA_1	830	836	PF00498	0.509
LIG_FHA_1	930	936	PF00498	0.453
LIG_FHA_2	1015	1021	PF00498	0.457
LIG_FHA_2	1059	1065	PF00498	0.485
LIG_FHA_2	124	130	PF00498	0.728
LIG_FHA_2	176	182	PF00498	0.308
LIG_FHA_2	260	266	PF00498	0.394
LIG_FHA_2	33	39	PF00498	0.454
LIG_FHA_2	371	377	PF00498	0.384
LIG_FHA_2	41	47	PF00498	0.411
LIG_FHA_2	630	636	PF00498	0.397
LIG_FHA_2	773	779	PF00498	0.524
LIG_FHA_2	894	900	PF00498	0.468
LIG_GBD_Chelix_1	815	823	PF00786	0.358
LIG_LIR_Gen_1	1067	1074	PF02991	0.511
LIG_LIR_Gen_1	1088	1099	PF02991	0.515
LIG_LIR_Gen_1	277	287	PF02991	0.327
LIG_LIR_Gen_1	310	320	PF02991	0.336
LIG_LIR_Gen_1	376	386	PF02991	0.327
LIG_LIR_Gen_1	635	644	PF02991	0.438
LIG_LIR_Gen_1	790	799	PF02991	0.468
LIG_LIR_Gen_1	822	833	PF02991	0.443
LIG_LIR_Gen_1	840	847	PF02991	0.508
LIG_LIR_Gen_1	919	930	PF02991	0.464
LIG_LIR_Gen_1	989	996	PF02991	0.514
LIG_LIR_LC3C_4	297	302	PF02991	0.308
LIG_LIR_Nem_3	1063	1069	PF02991	0.472
LIG_LIR_Nem_3	1088	1094	PF02991	0.541
LIG_LIR_Nem_3	1121	1126	PF02991	0.377
LIG_LIR_Nem_3	142	147	PF02991	0.411
LIG_LIR_Nem_3	167	172	PF02991	0.352
LIG_LIR_Nem_3	277	282	PF02991	0.339
LIG_LIR_Nem_3	292	298	PF02991	0.267
LIG_LIR_Nem_3	310	315	PF02991	0.308
LIG_LIR_Nem_3	373	378	PF02991	0.306
LIG_LIR_Nem_3	410	415	PF02991	0.329
LIG_LIR_Nem_3	422	428	PF02991	0.309
LIG_LIR_Nem_3	444	449	PF02991	0.457
LIG_LIR_Nem_3	512	518	PF02991	0.451
LIG_LIR_Nem_3	59	64	PF02991	0.473
LIG_LIR_Nem_3	632	636	PF02991	0.475
LIG_LIR_Nem_3	790	794	PF02991	0.460
LIG_LIR_Nem_3	810	814	PF02991	0.322
LIG_LIR_Nem_3	822	828	PF02991	0.429
LIG_LIR_Nem_3	840	845	PF02991	0.500
LIG_LIR_Nem_3	885	890	PF02991	0.387
LIG_LIR_Nem_3	891	895	PF02991	0.460
LIG_LIR_Nem_3	905	911	PF02991	0.322
LIG_LIR_Nem_3	919	925	PF02991	0.440
LIG_LIR_Nem_3	989	993	PF02991	0.484
LIG_LYPXL_S_1	784	788	PF13949	0.285
LIG_LYPXL_yS_3	785	788	PF13949	0.485
LIG_LYPXL_yS_3	811	814	PF13949	0.485
LIG_MYND_1	58	62	PF01753	0.523
LIG_NRBOX	155	161	PF00104	0.308
LIG_NRBOX	548	554	PF00104	0.394
LIG_NRBOX	869	875	PF00104	0.454
LIG_PCNA_yPIPBox_3	157	170	PF02747	0.308
LIG_PCNA_yPIPBox_3	594	606	PF02747	0.532
LIG_Pex14_2	312	316	PF04695	0.355
LIG_Pex14_2	412	416	PF04695	0.327
LIG_Pex14_2	442	446	PF04695	0.308
LIG_PTB_Apo_2	805	812	PF02174	0.377
LIG_PTB_Phospho_1	805	811	PF10480	0.377
LIG_Rb_LxCxE_1	753	767	PF01857	0.452
LIG_SH2_CRK	107	111	PF00017	0.587
LIG_SH2_CRK	1091	1095	PF00017	0.534
LIG_SH2_CRK	144	148	PF00017	0.327
LIG_SH2_CRK	174	178	PF00017	0.327
LIG_SH2_CRK	465	469	PF00017	0.327
LIG_SH2_CRK	515	519	PF00017	0.374
LIG_SH2_CRK	644	648	PF00017	0.509
LIG_SH2_CRK	842	846	PF00017	0.468
LIG_SH2_GRB2like	1069	1072	PF00017	0.558
LIG_SH2_GRB2like	107	110	PF00017	0.649
LIG_SH2_GRB2like	155	158	PF00017	0.308
LIG_SH2_GRB2like	377	380	PF00017	0.350
LIG_SH2_NCK_1	107	111	PF00017	0.673
LIG_SH2_NCK_1	1091	1095	PF00017	0.534
LIG_SH2_PTP2	279	282	PF00017	0.380
LIG_SH2_SRC	107	110	PF00017	0.577
LIG_SH2_SRC	155	158	PF00017	0.308
LIG_SH2_SRC	362	365	PF00017	0.340
LIG_SH2_SRC	513	516	PF00017	0.519
LIG_SH2_SRC	948	951	PF00017	0.377
LIG_SH2_STAP1	296	300	PF00017	0.327
LIG_SH2_STAP1	831	835	PF00017	0.377
LIG_SH2_STAT3	115	118	PF00017	0.719
LIG_SH2_STAT3	198	201	PF00017	0.327
LIG_SH2_STAT3	296	299	PF00017	0.327
LIG_SH2_STAT5	1069	1072	PF00017	0.468
LIG_SH2_STAT5	155	158	PF00017	0.318
LIG_SH2_STAT5	279	282	PF00017	0.380
LIG_SH2_STAT5	327	330	PF00017	0.325
LIG_SH2_STAT5	34	37	PF00017	0.586
LIG_SH2_STAT5	397	400	PF00017	0.343
LIG_SH2_STAT5	415	418	PF00017	0.225
LIG_SH2_STAT5	469	472	PF00017	0.332
LIG_SH2_STAT5	513	516	PF00017	0.456
LIG_SH2_STAT5	532	535	PF00017	0.394
LIG_SH2_STAT5	831	834	PF00017	0.458
LIG_SH2_STAT5	858	861	PF00017	0.454
LIG_SH2_STAT5	887	890	PF00017	0.314
LIG_SH2_STAT5	892	895	PF00017	0.449
LIG_SH3_3	1106	1112	PF00018	0.475
LIG_SH3_3	385	391	PF00018	0.362
LIG_SH3_3	429	435	PF00018	0.322
LIG_SH3_3	613	619	PF00018	0.497
LIG_SH3_3	705	711	PF00018	0.715
LIG_SH3_3	780	786	PF00018	0.464
LIG_SH3_3	806	812	PF00018	0.468
LIG_SUMO_SIM_anti_2	1157	1164	PF11976	0.629
LIG_SUMO_SIM_par_1	379	384	PF11976	0.380
LIG_SUMO_SIM_par_1	623	628	PF11976	0.511
LIG_SUMO_SIM_par_1	810	818	PF11976	0.558
LIG_SxIP_EBH_1	450	464	PF03271	0.419
LIG_TRAF2_1	1017	1020	PF00917	0.468
LIG_TRAF2_1	290	293	PF00917	0.380
LIG_TRAF2_1	728	731	PF00917	0.666
LIG_TYR_ITAM	808	828	PF00017	0.377
LIG_TYR_ITIM	105	110	PF00017	0.603
LIG_TYR_ITIM	783	788	PF00017	0.468
LIG_UBA3_1	1	9	PF00899	0.449
LIG_UBA3_1	1079	1086	PF00899	0.468
LIG_UBA3_1	172	179	PF00899	0.419
LIG_UBA3_1	243	250	PF00899	0.308
LIG_UBA3_1	681	690	PF00899	0.608
LIG_UBA3_1	979	985	PF00899	0.534
LIG_WRC_WIRS_1	309	314	PF05994	0.350
LIG_WRC_WIRS_1	788	793	PF05994	0.384
MOD_CDK_SPK_2	259	264	PF00069	0.297
MOD_CDK_SPxK_1	431	437	PF00069	0.419
MOD_CK1_1	1150	1156	PF00069	0.630
MOD_CK1_1	187	193	PF00069	0.379
MOD_CK1_1	275	281	PF00069	0.406
MOD_CK1_1	390	396	PF00069	0.448
MOD_CK1_1	473	479	PF00069	0.497
MOD_CK1_1	545	551	PF00069	0.456
MOD_CK1_1	582	588	PF00069	0.582
MOD_CK1_1	713	719	PF00069	0.680
MOD_CK1_1	96	102	PF00069	0.584
MOD_CK2_1	1014	1020	PF00069	0.459
MOD_CK2_1	1058	1064	PF00069	0.530
MOD_CK2_1	111	117	PF00069	0.698
MOD_CK2_1	175	181	PF00069	0.308
MOD_CK2_1	22	28	PF00069	0.524
MOD_CK2_1	259	265	PF00069	0.394
MOD_CK2_1	287	293	PF00069	0.350
MOD_CK2_1	40	46	PF00069	0.437
MOD_CK2_1	605	611	PF00069	0.388
MOD_CK2_1	629	635	PF00069	0.409
MOD_CK2_1	725	731	PF00069	0.620
MOD_CK2_1	772	778	PF00069	0.524
MOD_CK2_1	893	899	PF00069	0.456
MOD_CK2_1	983	989	PF00069	0.565
MOD_Cter_Amidation	1153	1156	PF01082	0.682
MOD_Cter_Amidation	332	335	PF01082	0.350
MOD_Cter_Amidation	861	864	PF01082	0.285
MOD_GlcNHglycan	1019	1023	PF01048	0.255
MOD_GlcNHglycan	405	408	PF01048	0.308
MOD_GlcNHglycan	421	424	PF01048	0.308
MOD_GlcNHglycan	607	610	PF01048	0.433
MOD_GlcNHglycan	662	666	PF01048	0.570
MOD_GlcNHglycan	712	715	PF01048	0.753
MOD_GlcNHglycan	764	767	PF01048	0.255
MOD_GlcNHglycan	90	93	PF01048	0.553
MOD_GlcNHglycan	918	921	PF01048	0.264
MOD_GlcNHglycan	98	101	PF01048	0.558
MOD_GlcNHglycan	985	988	PF01048	0.355
MOD_GSK3_1	1014	1021	PF00069	0.481
MOD_GSK3_1	1060	1067	PF00069	0.503
MOD_GSK3_1	184	191	PF00069	0.351
MOD_GSK3_1	213	220	PF00069	0.308
MOD_GSK3_1	249	256	PF00069	0.387
MOD_GSK3_1	30	37	PF00069	0.527
MOD_GSK3_1	366	373	PF00069	0.327
MOD_GSK3_1	377	384	PF00069	0.327
MOD_GSK3_1	403	410	PF00069	0.377
MOD_GSK3_1	469	476	PF00069	0.472
MOD_GSK3_1	614	621	PF00069	0.482
MOD_GSK3_1	706	713	PF00069	0.678
MOD_N-GLC_1	1072	1077	PF02516	0.177
MOD_N-GLC_1	110	115	PF02516	0.637
MOD_N-GLC_1	13	18	PF02516	0.571
MOD_N-GLC_1	259	264	PF02516	0.199
MOD_N-GLC_1	686	691	PF02516	0.400
MOD_N-GLC_1	968	973	PF02516	0.319
MOD_N-GLC_2	1122	1124	PF02516	0.334
MOD_NEK2_1	1072	1077	PF00069	0.527
MOD_NEK2_1	1115	1120	PF00069	0.534
MOD_NEK2_1	164	169	PF00069	0.344
MOD_NEK2_1	207	212	PF00069	0.252
MOD_NEK2_1	219	224	PF00069	0.241
MOD_NEK2_1	381	386	PF00069	0.327
MOD_NEK2_1	403	408	PF00069	0.308
MOD_NEK2_1	419	424	PF00069	0.308
MOD_NEK2_1	580	585	PF00069	0.508
MOD_NEK2_1	605	610	PF00069	0.503
MOD_NEK2_1	64	69	PF00069	0.538
MOD_NEK2_1	654	659	PF00069	0.417
MOD_PIKK_1	470	476	PF00454	0.480
MOD_PIKK_1	537	543	PF00454	0.568
MOD_PIKK_1	563	569	PF00454	0.292
MOD_PKA_2	1036	1042	PF00069	0.377
MOD_PKA_2	46	52	PF00069	0.516
MOD_PKA_2	470	476	PF00069	0.375
MOD_PKA_2	590	596	PF00069	0.552
MOD_PKA_2	749	755	PF00069	0.560
MOD_PKA_2	829	835	PF00069	0.377
MOD_PKA_2	845	851	PF00069	0.454
MOD_PKA_2	866	872	PF00069	0.462
MOD_Plk_1	110	116	PF00069	0.641
MOD_Plk_1	13	19	PF00069	0.540
MOD_Plk_1	188	194	PF00069	0.433
MOD_Plk_1	237	243	PF00069	0.350
MOD_Plk_1	381	387	PF00069	0.350
MOD_Plk_1	821	827	PF00069	0.468
MOD_Plk_1	968	974	PF00069	0.544
MOD_Plk_2-3	1014	1020	PF00069	0.485
MOD_Plk_2-3	821	827	PF00069	0.468
MOD_Plk_4	155	161	PF00069	0.322
MOD_Plk_4	227	233	PF00069	0.327
MOD_Plk_4	275	281	PF00069	0.350
MOD_Plk_4	398	404	PF00069	0.308
MOD_Plk_4	474	480	PF00069	0.493
MOD_Plk_4	56	62	PF00069	0.475
MOD_Plk_4	654	660	PF00069	0.374
MOD_Plk_4	80	86	PF00069	0.530
MOD_ProDKin_1	259	265	PF00069	0.440
MOD_ProDKin_1	387	393	PF00069	0.452
MOD_ProDKin_1	431	437	PF00069	0.380
MOD_ProDKin_1	615	621	PF00069	0.482
MOD_ProDKin_1	772	778	PF00069	0.507
MOD_ProDKin_1	93	99	PF00069	0.506
MOD_SUMO_for_1	1085	1088	PF00179	0.534
MOD_SUMO_for_1	280	283	PF00179	0.452
MOD_SUMO_rev_2	245	252	PF00179	0.313
MOD_SUMO_rev_2	363	372	PF00179	0.327
TRG_DiLeu_BaEn_1	1157	1162	PF01217	0.666
TRG_DiLeu_BaEn_1	611	616	PF01217	0.417
TRG_DiLeu_BaEn_1	989	994	PF01217	0.534
TRG_DiLeu_BaEn_2	752	758	PF01217	0.534
TRG_DiLeu_BaEn_2	854	860	PF01217	0.534
TRG_DiLeu_BaLyEn_6	100	105	PF01217	0.624
TRG_DiLeu_BaLyEn_6	809	814	PF01217	0.518
TRG_DiLeu_BaLyEn_6	831	836	PF01217	0.507
TRG_DiLeu_BaLyEn_6	869	874	PF01217	0.507
TRG_ENDOCYTIC_2	1002	1005	PF00928	0.485
TRG_ENDOCYTIC_2	1069	1072	PF00928	0.510
TRG_ENDOCYTIC_2	107	110	PF00928	0.589
TRG_ENDOCYTIC_2	1091	1094	PF00928	0.533
TRG_ENDOCYTIC_2	144	147	PF00928	0.361
TRG_ENDOCYTIC_2	279	282	PF00928	0.362
TRG_ENDOCYTIC_2	309	312	PF00928	0.308
TRG_ENDOCYTIC_2	378	381	PF00928	0.299
TRG_ENDOCYTIC_2	415	418	PF00928	0.308
TRG_ENDOCYTIC_2	465	468	PF00928	0.308
TRG_ENDOCYTIC_2	515	518	PF00928	0.404
TRG_ENDOCYTIC_2	636	639	PF00928	0.419
TRG_ENDOCYTIC_2	644	647	PF00928	0.362
TRG_ENDOCYTIC_2	785	788	PF00928	0.468
TRG_ENDOCYTIC_2	811	814	PF00928	0.378
TRG_ENDOCYTIC_2	825	828	PF00928	0.408
TRG_ENDOCYTIC_2	842	845	PF00928	0.464
TRG_ER_diArg_1	1052	1055	PF00400	0.485
TRG_ER_diArg_1	1080	1082	PF00400	0.507
TRG_ER_diArg_1	504	506	PF00400	0.586
TRG_ER_diArg_1	536	538	PF00400	0.574
TRG_ER_diArg_1	737	739	PF00400	0.517
TRG_ER_diArg_1	844	847	PF00400	0.468
TRG_ER_diArg_1	997	1000	PF00400	0.534
TRG_Pf-PMV_PEXEL_1	241	245	PF00026	0.380
TRG_Pf-PMV_PEXEL_1	550	554	PF00026	0.405
TRG_Pf-PMV_PEXEL_1	603	607	PF00026	0.521
TRG_Pf-PMV_PEXEL_1	679	684	PF00026	0.568
TRG_Pf-PMV_PEXEL_1	834	838	PF00026	0.307

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIY9	Leptomonas seymouri	76%	100%
A0A0S4KFL3	Bodo saltans	36%	90%
A0A1X0P648	Trypanosomatidae	55%	100%
A0A3S7X936	Leishmania donovani	90%	100%
A0A422NQC0	Trypanosoma rangeli	54%	100%
A4IB74	Leishmania infantum	90%	100%
C9ZZI4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	100%
E9AEZ5	Leishmania major	90%	100%
E9B651	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4VSI4	Rattus norvegicus	28%	100%
Q6A4J8	Mus musculus	28%	100%
Q6U7I1	Gallus gallus	28%	100%
Q93009	Homo sapiens	28%	100%
Q9VYQ8	Drosophila melanogaster	30%	100%