LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

CX9C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
CX9C domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4HMC0_LEIBR
TriTrypDb:
LbrM.34.0880 , LBRM2903_340014500
Length:
165

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0031974 membrane-enclosed lumen 2 1
GO:0031981 nuclear lumen 5 1
GO:0032838 plasma membrane bounded cell projection cytoplasm 4 1
GO:0043233 organelle lumen 3 1
GO:0070013 intracellular organelle lumen 4 1
GO:0097014 ciliary plasm 5 1
GO:0099568 cytoplasmic region 3 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4HMC0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HMC0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 95 99 PF00656 0.522
DEG_Nend_Nbox_1 1 3 PF02207 0.756
DEG_SPOP_SBC_1 77 81 PF00917 0.703
DEG_SPOP_SBC_1 83 87 PF00917 0.737
DOC_CYCLIN_yCln2_LP_2 47 53 PF00134 0.586
DOC_PP4_FxxP_1 111 114 PF00568 0.445
DOC_USP7_MATH_1 24 28 PF00917 0.667
DOC_USP7_MATH_1 83 87 PF00917 0.721
DOC_USP7_UBL2_3 52 56 PF12436 0.524
DOC_USP7_UBL2_3 6 10 PF12436 0.678
DOC_WW_Pin1_4 46 51 PF00397 0.584
DOC_WW_Pin1_4 85 90 PF00397 0.746
LIG_FHA_2 102 108 PF00498 0.555
LIG_FHA_2 36 42 PF00498 0.565
LIG_FHA_2 93 99 PF00498 0.515
LIG_LIR_Apic_2 108 114 PF02991 0.446
LIG_LIR_Apic_2 3 8 PF02991 0.490
LIG_LIR_Nem_3 107 113 PF02991 0.586
LIG_LIR_Nem_3 27 32 PF02991 0.570
LIG_SH2_CRK 5 9 PF00017 0.498
LIG_SH2_CRK 69 73 PF00017 0.654
LIG_SH2_STAP1 119 123 PF00017 0.524
LIG_SH3_3 86 92 PF00018 0.766
MOD_CDC14_SPxK_1 49 52 PF00782 0.495
MOD_CDK_SPxK_1 46 52 PF00069 0.490
MOD_CK1_1 101 107 PF00069 0.629
MOD_CK1_1 35 41 PF00069 0.658
MOD_CK1_1 76 82 PF00069 0.715
MOD_CK1_1 85 91 PF00069 0.673
MOD_CK1_1 94 100 PF00069 0.693
MOD_GlcNHglycan 75 78 PF01048 0.629
MOD_GSK3_1 72 79 PF00069 0.626
MOD_GSK3_1 92 99 PF00069 0.680
MOD_NEK2_1 1 6 PF00069 0.751
MOD_NEK2_1 51 56 PF00069 0.596
MOD_NEK2_1 72 77 PF00069 0.629
MOD_PIKK_1 33 39 PF00454 0.516
MOD_Plk_1 129 135 PF00069 0.550
MOD_Plk_4 35 41 PF00069 0.660
MOD_ProDKin_1 46 52 PF00069 0.588
MOD_ProDKin_1 85 91 PF00069 0.743
MOD_SUMO_rev_2 27 32 PF00179 0.678
MOD_SUMO_rev_2 94 102 PF00179 0.730
TRG_ENDOCYTIC_2 69 72 PF00928 0.652

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3P8 Leptomonas seymouri 64% 93%
A0A1X0NIU2 Trypanosomatidae 35% 100%
A0A3R7KNC4 Trypanosoma rangeli 37% 96%
A0A3S7X8W7 Leishmania donovani 78% 100%
A4IAY6 Leishmania infantum 78% 100%
C9ZNI3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 40% 100%
E9AER4 Leishmania major 81% 100%
E9B5W9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 100%
V5D1X1 Trypanosoma cruzi 38% 99%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS