Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HM82_LEIBR

TriTrypDb:

LbrM.34.0490

Length:

259

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HM82

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HM82

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	196	198	PF00675	0.739
CLV_NRD_NRD_1	255	257	PF00675	0.613
CLV_PCSK_KEX2_1	167	169	PF00082	0.658
CLV_PCSK_KEX2_1	196	198	PF00082	0.726
CLV_PCSK_KEX2_1	227	229	PF00082	0.677
CLV_PCSK_KEX2_1	255	257	PF00082	0.613
CLV_PCSK_PC1ET2_1	167	169	PF00082	0.684
CLV_PCSK_PC1ET2_1	227	229	PF00082	0.651
DEG_Nend_UBRbox_3	1	3	PF02207	0.622
DOC_MAPK_RevD_3	206	220	PF00069	0.412
DOC_PP4_FxxP_1	29	32	PF00568	0.622
DOC_USP7_MATH_1	145	149	PF00917	0.417
DOC_USP7_MATH_1	63	67	PF00917	0.619
DOC_WW_Pin1_4	16	21	PF00397	0.643
DOC_WW_Pin1_4	28	33	PF00397	0.646
DOC_WW_Pin1_4	9	14	PF00397	0.713
LIG_14-3-3_CanoR_1	237	244	PF00244	0.433
LIG_APCC_ABBA_1	21	26	PF00400	0.599
LIG_FHA_1	17	23	PF00498	0.625
LIG_FHA_1	183	189	PF00498	0.513
LIG_FHA_1	221	227	PF00498	0.564
LIG_LIR_Apic_2	139	145	PF02991	0.473
LIG_LIR_Apic_2	26	32	PF02991	0.619
LIG_LIR_Gen_1	111	121	PF02991	0.383
LIG_LIR_LC3C_4	19	23	PF02991	0.593
LIG_LIR_Nem_3	111	117	PF02991	0.264
LIG_NRBOX	112	118	PF00104	0.351
LIG_Pex14_2	110	114	PF04695	0.282
LIG_Pex14_2	133	137	PF04695	0.391
LIG_PROFILIN_1	88	94	PF00235	0.570
LIG_SH2_SRC	142	145	PF00017	0.477
LIG_SH2_STAT5	142	145	PF00017	0.411
LIG_SH2_STAT5	47	50	PF00017	0.611
LIG_SH3_1	87	93	PF00018	0.700
LIG_SH3_2	163	168	PF14604	0.433
LIG_SH3_3	160	166	PF00018	0.433
LIG_SH3_3	206	212	PF00018	0.519
LIG_SH3_3	85	91	PF00018	0.709
LIG_SUMO_SIM_anti_2	79	86	PF11976	0.663
LIG_SUMO_SIM_par_1	79	86	PF11976	0.601
LIG_WRC_WIRS_1	134	139	PF05994	0.467
MOD_CDC14_SPxK_1	31	34	PF00782	0.632
MOD_CDK_SPxK_1	28	34	PF00069	0.625
MOD_CK1_1	149	155	PF00069	0.494
MOD_CK1_1	161	167	PF00069	0.479
MOD_CK1_1	179	185	PF00069	0.503
MOD_CK1_1	238	244	PF00069	0.457
MOD_CK1_1	50	56	PF00069	0.645
MOD_CK1_1	71	77	PF00069	0.597
MOD_CK1_1	9	15	PF00069	0.601
MOD_GlcNHglycan	117	120	PF01048	0.577
MOD_GlcNHglycan	16	19	PF01048	0.434
MOD_GlcNHglycan	201	204	PF01048	0.645
MOD_GlcNHglycan	54	57	PF01048	0.516
MOD_GlcNHglycan	64	68	PF01048	0.521
MOD_GlcNHglycan	74	77	PF01048	0.376
MOD_GSK3_1	145	152	PF00069	0.468
MOD_GSK3_1	68	75	PF00069	0.611
MOD_N-GLC_1	199	204	PF02516	0.629
MOD_N-GLC_1	6	11	PF02516	0.404
MOD_NEK2_1	121	126	PF00069	0.408
MOD_NEK2_1	133	138	PF00069	0.533
MOD_NEK2_1	14	19	PF00069	0.693
MOD_NEK2_1	158	163	PF00069	0.514
MOD_NEK2_1	72	77	PF00069	0.595
MOD_PKA_1	167	173	PF00069	0.458
MOD_PKA_1	219	225	PF00069	0.425
MOD_PKA_2	167	173	PF00069	0.501
MOD_PKA_2	190	196	PF00069	0.512
MOD_PKA_2	238	244	PF00069	0.431
MOD_PKA_2	33	39	PF00069	0.633
MOD_Plk_1	50	56	PF00069	0.597
MOD_Plk_4	146	152	PF00069	0.485
MOD_ProDKin_1	16	22	PF00069	0.642
MOD_ProDKin_1	28	34	PF00069	0.649
MOD_ProDKin_1	9	15	PF00069	0.712
MOD_SUMO_for_1	166	169	PF00179	0.435
TRG_DiLeu_BaLyEn_6	77	82	PF01217	0.661
TRG_ER_diArg_1	255	258	PF00400	0.414
TRG_NES_CRM1_1	111	127	PF08389	0.368

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X8T7	Leishmania donovani	40%	100%
A4IAU6	Leishmania infantum	47%	100%