Sperm-tail_PG-rich_repeat

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4HM79_LEIBR

TriTrypDb:

LbrM.34.0450 , LBRM2903_340009600

Length:

566

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4HM79

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HM79

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	458	462	PF00656	0.671
CLV_NRD_NRD_1	213	215	PF00675	0.698
CLV_NRD_NRD_1	256	258	PF00675	0.308
CLV_NRD_NRD_1	292	294	PF00675	0.762
CLV_NRD_NRD_1	332	334	PF00675	0.633
CLV_NRD_NRD_1	341	343	PF00675	0.692
CLV_NRD_NRD_1	426	428	PF00675	0.742
CLV_NRD_NRD_1	562	564	PF00675	0.766
CLV_NRD_NRD_1	76	78	PF00675	0.685
CLV_PCSK_FUR_1	241	245	PF00082	0.365
CLV_PCSK_KEX2_1	213	215	PF00082	0.735
CLV_PCSK_KEX2_1	243	245	PF00082	0.324
CLV_PCSK_KEX2_1	258	260	PF00082	0.700
CLV_PCSK_KEX2_1	292	294	PF00082	0.771
CLV_PCSK_KEX2_1	341	343	PF00082	0.663
CLV_PCSK_KEX2_1	37	39	PF00082	0.558
CLV_PCSK_KEX2_1	426	428	PF00082	0.741
CLV_PCSK_KEX2_1	562	564	PF00082	0.795
CLV_PCSK_KEX2_1	76	78	PF00082	0.628
CLV_PCSK_PC1ET2_1	243	245	PF00082	0.334
CLV_PCSK_PC1ET2_1	258	260	PF00082	0.537
CLV_PCSK_PC1ET2_1	37	39	PF00082	0.554
CLV_PCSK_SKI1_1	173	177	PF00082	0.645
CLV_PCSK_SKI1_1	243	247	PF00082	0.362
CLV_PCSK_SKI1_1	38	42	PF00082	0.553
CLV_Separin_Metazoa	199	203	PF03568	0.696
DEG_Nend_Nbox_1	1	3	PF02207	0.659
DEG_SCF_FBW7_1	114	120	PF00400	0.613
DEG_SIAH_1	139	147	PF03145	0.483
DEG_SPOP_SBC_1	31	35	PF00917	0.633
DOC_CDC14_PxL_1	312	320	PF14671	0.507
DOC_CKS1_1	114	119	PF01111	0.617
DOC_CKS1_1	261	266	PF01111	0.681
DOC_CYCLIN_RxL_1	240	250	PF00134	0.558
DOC_MAPK_gen_1	202	209	PF00069	0.487
DOC_PP4_FxxP_1	261	264	PF00568	0.636
DOC_PP4_FxxP_1	369	372	PF00568	0.524
DOC_USP7_MATH_1	31	35	PF00917	0.521
DOC_USP7_MATH_1	317	321	PF00917	0.648
DOC_USP7_MATH_1	351	355	PF00917	0.694
DOC_USP7_MATH_1	363	367	PF00917	0.671
DOC_USP7_MATH_1	484	488	PF00917	0.747
DOC_USP7_MATH_1	75	79	PF00917	0.734
DOC_USP7_MATH_1	86	90	PF00917	0.690
DOC_USP7_UBL2_3	278	282	PF12436	0.703
DOC_WW_Pin1_4	113	118	PF00397	0.609
DOC_WW_Pin1_4	134	139	PF00397	0.682
DOC_WW_Pin1_4	218	223	PF00397	0.664
DOC_WW_Pin1_4	260	265	PF00397	0.687
DOC_WW_Pin1_4	284	289	PF00397	0.533
DOC_WW_Pin1_4	349	354	PF00397	0.547
DOC_WW_Pin1_4	380	385	PF00397	0.732
LIG_14-3-3_CanoR_1	244	252	PF00244	0.586
LIG_14-3-3_CanoR_1	299	303	PF00244	0.724
LIG_14-3-3_CanoR_1	403	411	PF00244	0.570
LIG_14-3-3_CanoR_1	427	433	PF00244	0.736
LIG_14-3-3_CanoR_1	435	442	PF00244	0.620
LIG_14-3-3_CanoR_1	525	529	PF00244	0.589
LIG_BRCT_BRCA1_1	248	252	PF00533	0.492
LIG_BRCT_BRCA1_1	286	290	PF00533	0.634
LIG_BRCT_BRCA1_1	365	369	PF00533	0.747
LIG_BRCT_BRCA1_1	70	74	PF00533	0.655
LIG_DLG_GKlike_1	342	349	PF00625	0.552
LIG_FHA_1	275	281	PF00498	0.650
LIG_FHA_1	423	429	PF00498	0.666
LIG_FHA_1	515	521	PF00498	0.609
LIG_FHA_1	535	541	PF00498	0.572
LIG_FHA_2	381	387	PF00498	0.731
LIG_LIR_Apic_2	22	26	PF02991	0.604
LIG_LIR_Apic_2	260	264	PF02991	0.507
LIG_LIR_Apic_2	366	372	PF02991	0.529
LIG_LIR_Apic_2	527	533	PF02991	0.584
LIG_LIR_Gen_1	43	51	PF02991	0.458
LIG_LIR_Gen_1	6	13	PF02991	0.558
LIG_LIR_Nem_3	320	324	PF02991	0.529
LIG_LIR_Nem_3	43	48	PF02991	0.457
LIG_LIR_Nem_3	6	11	PF02991	0.557
LIG_PCNA_yPIPBox_3	236	246	PF02747	0.405
LIG_Pex14_2	252	256	PF04695	0.562
LIG_Pex14_2	328	332	PF04695	0.696
LIG_RPA_C_Fungi	337	349	PF08784	0.535
LIG_SH2_CRK	271	275	PF00017	0.652
LIG_SH2_CRK	530	534	PF00017	0.574
LIG_SH2_NCK_1	227	231	PF00017	0.378
LIG_SH2_NCK_1	23	27	PF00017	0.685
LIG_SH2_PTP2	143	146	PF00017	0.491
LIG_SH2_PTP2	45	48	PF00017	0.482
LIG_SH2_SRC	227	230	PF00017	0.378
LIG_SH2_SRC	385	388	PF00017	0.438
LIG_SH2_STAP1	108	112	PF00017	0.658
LIG_SH2_STAP1	502	506	PF00017	0.654
LIG_SH2_STAP1	544	548	PF00017	0.685
LIG_SH2_STAT5	143	146	PF00017	0.624
LIG_SH2_STAT5	148	151	PF00017	0.654
LIG_SH2_STAT5	45	48	PF00017	0.728
LIG_SH2_STAT5	516	519	PF00017	0.603
LIG_SH2_STAT5	530	533	PF00017	0.576
LIG_SH2_STAT5	60	63	PF00017	0.555
LIG_SH3_3	111	117	PF00018	0.595
LIG_SH3_3	182	188	PF00018	0.516
LIG_SH3_3	319	325	PF00018	0.660
LIG_SH3_3	369	375	PF00018	0.694
LIG_SH3_3	381	387	PF00018	0.537
LIG_SH3_3	408	414	PF00018	0.548
LIG_SH3_3	445	451	PF00018	0.660
LIG_SH3_3	98	104	PF00018	0.575
LIG_TRAF2_1	483	486	PF00917	0.649
LIG_TRFH_1	23	27	PF08558	0.685
LIG_UBA3_1	432	440	PF00899	0.497
MOD_CDK_SPK_2	284	289	PF00069	0.503
MOD_CK1_1	320	326	PF00069	0.702
MOD_CK1_1	33	39	PF00069	0.606
MOD_CK1_1	388	394	PF00069	0.419
MOD_CK1_1	438	444	PF00069	0.666
MOD_CK1_1	462	468	PF00069	0.756
MOD_CK1_1	47	53	PF00069	0.543
MOD_CK1_1	79	85	PF00069	0.733
MOD_CK1_1	95	101	PF00069	0.714
MOD_CK2_1	298	304	PF00069	0.688
MOD_CK2_1	480	486	PF00069	0.750
MOD_Cter_Amidation	339	342	PF01082	0.523
MOD_GlcNHglycan	126	129	PF01048	0.671
MOD_GlcNHglycan	161	164	PF01048	0.713
MOD_GlcNHglycan	311	315	PF01048	0.661
MOD_GlcNHglycan	363	366	PF01048	0.789
MOD_GlcNHglycan	386	390	PF01048	0.571
MOD_GlcNHglycan	437	440	PF01048	0.686
MOD_GlcNHglycan	442	445	PF01048	0.697
MOD_GlcNHglycan	477	480	PF01048	0.653
MOD_GlcNHglycan	482	485	PF01048	0.670
MOD_GlcNHglycan	53	56	PF01048	0.557
MOD_GlcNHglycan	80	84	PF01048	0.706
MOD_GlcNHglycan	88	91	PF01048	0.659
MOD_GSK3_1	113	120	PF00069	0.604
MOD_GSK3_1	130	137	PF00069	0.407
MOD_GSK3_1	244	251	PF00069	0.480
MOD_GSK3_1	270	277	PF00069	0.703
MOD_GSK3_1	32	39	PF00069	0.606
MOD_GSK3_1	349	356	PF00069	0.757
MOD_GSK3_1	40	47	PF00069	0.588
MOD_GSK3_1	480	487	PF00069	0.743
MOD_GSK3_1	75	82	PF00069	0.644
MOD_LATS_1	473	479	PF00433	0.762
MOD_NEK2_1	246	251	PF00069	0.227
MOD_NEK2_1	274	279	PF00069	0.705
MOD_PIKK_1	244	250	PF00454	0.480
MOD_PIKK_1	552	558	PF00454	0.760
MOD_PKA_1	76	82	PF00069	0.627
MOD_PKA_2	209	215	PF00069	0.749
MOD_PKA_2	298	304	PF00069	0.673
MOD_PKA_2	402	408	PF00069	0.677
MOD_PKA_2	462	468	PF00069	0.581
MOD_PKA_2	524	530	PF00069	0.604
MOD_PKA_2	552	558	PF00069	0.512
MOD_PKA_2	69	75	PF00069	0.553
MOD_PKA_2	76	82	PF00069	0.573
MOD_Plk_1	484	490	PF00069	0.729
MOD_Plk_1	497	503	PF00069	0.628
MOD_Plk_1	95	101	PF00069	0.514
MOD_Plk_2-3	298	304	PF00069	0.758
MOD_Plk_4	428	434	PF00069	0.737
MOD_Plk_4	462	468	PF00069	0.640
MOD_Plk_4	497	503	PF00069	0.659
MOD_ProDKin_1	113	119	PF00069	0.613
MOD_ProDKin_1	134	140	PF00069	0.683
MOD_ProDKin_1	218	224	PF00069	0.403
MOD_ProDKin_1	260	266	PF00069	0.684
MOD_ProDKin_1	284	290	PF00069	0.536
MOD_ProDKin_1	349	355	PF00069	0.549
MOD_ProDKin_1	380	386	PF00069	0.722
MOD_SUMO_rev_2	354	364	PF00179	0.546
TRG_DiLeu_BaLyEn_6	241	246	PF01217	0.227
TRG_ENDOCYTIC_2	271	274	PF00928	0.592
TRG_ENDOCYTIC_2	45	48	PF00928	0.482
TRG_ENDOCYTIC_2	454	457	PF00928	0.724
TRG_ENDOCYTIC_2	8	11	PF00928	0.678
TRG_ER_diArg_1	11	14	PF00400	0.573
TRG_ER_diArg_1	201	204	PF00400	0.697
TRG_ER_diArg_1	256	259	PF00400	0.358
TRG_ER_diArg_1	291	293	PF00400	0.780
TRG_ER_diArg_1	426	428	PF00400	0.742
TRG_ER_diArg_1	561	563	PF00400	0.792
TRG_NLS_MonoExtC_3	394	400	PF00514	0.430
TRG_Pf-PMV_PEXEL_1	244	248	PF00026	0.349

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBL9	Leptomonas seymouri	59%	100%
A0A0S4JMR6	Bodo saltans	25%	100%
A0A1X0NJC7	Trypanosomatidae	35%	100%
A0A3Q8IFZ9	Leishmania donovani	81%	100%
A0A3R7RG79	Trypanosoma rangeli	35%	100%
A4IAU2	Leishmania infantum	81%	100%
D0A2A9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
E9AEM0	Leishmania major	80%	100%
E9B5S9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	79%