60S ribosomal protein L30

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

60S ribosomal protein L30

Species:

Leishmania braziliensis

UniProt:

A4HM63_LEIBR

TriTrypDb:

LbrM.34.0280 , LBRM2903_340007800

Length:

104

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 24

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0015934	large ribosomal subunit	4	8
GO:0022625	cytosolic large ribosomal subunit	5	8
GO:0032991	protein-containing complex	1	12
GO:0044391	ribosomal subunit	3	8
GO:1990904	ribonucleoprotein complex	2	12
GO:0005840	ribosome	5	4
GO:0043226	organelle	2	4
GO:0043228	non-membrane-bounded organelle	3	4
GO:0043229	intracellular organelle	3	4
GO:0043232	intracellular non-membrane-bounded organelle	4	4
GO:0110165	cellular anatomical entity	1	4

Expansion

Sequence features

A4HM63

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4HM63

PDB structure(s): 6az3_d

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	12
GO:0003723	RNA binding	4	12
GO:0003735	structural constituent of ribosome	2	8
GO:0005198	structural molecule activity	1	8
GO:0005488	binding	1	12
GO:0097159	organic cyclic compound binding	2	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	96	100	PF00656	0.403
CLV_NRD_NRD_1	54	56	PF00675	0.262
CLV_PCSK_KEX2_1	54	56	PF00082	0.362
CLV_PCSK_SKI1_1	24	28	PF00082	0.260
DEG_APCC_DBOX_1	39	47	PF00400	0.460
DOC_MAPK_gen_1	37	46	PF00069	0.460
DOC_MAPK_gen_1	85	94	PF00069	0.460
DOC_USP7_UBL2_3	4	8	PF12436	0.527
DOC_WW_Pin1_4	64	69	PF00397	0.466
LIG_BIR_II_1	1	5	PF00653	0.573
LIG_FHA_1	87	93	PF00498	0.527
LIG_LIR_Gen_1	59	69	PF02991	0.460
LIG_LIR_LC3C_4	41	45	PF02991	0.477
LIG_LIR_Nem_3	59	64	PF02991	0.460
LIG_PDZ_Class_2	99	104	PF00595	0.562
LIG_SH2_CRK	61	65	PF00017	0.460
LIG_SH2_STAT5	25	28	PF00017	0.460
LIG_SH2_STAT5	61	64	PF00017	0.472
LIG_SUMO_SIM_anti_2	41	47	PF11976	0.460
LIG_SUMO_SIM_par_1	41	47	PF11976	0.463
LIG_SUMO_SIM_par_1	89	96	PF11976	0.461
MOD_GlcNHglycan	21	24	PF01048	0.260
MOD_GlcNHglycan	72	75	PF01048	0.304
MOD_GlcNHglycan	80	83	PF01048	0.298
MOD_GSK3_1	4	11	PF00069	0.501
MOD_GSK3_1	60	67	PF00069	0.495
MOD_GSK3_1	86	93	PF00069	0.512
MOD_N-GLC_2	48	50	PF02516	0.327
MOD_NEK2_2	32	37	PF00069	0.503
MOD_OFUCOSY	83	90	PF10250	0.302
MOD_PIKK_1	26	32	PF00454	0.502
MOD_ProDKin_1	64	70	PF00069	0.466
TRG_ENDOCYTIC_2	61	64	PF00928	0.460
TRG_ER_diArg_1	53	55	PF00400	0.562

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PD37	Leptomonas seymouri	92%	100%
A0A0S4J4N7	Bodo saltans	82%	99%
A0A1D8PM75	Candida albicans (strain SC5314 / ATCC MYA-2876)	50%	98%
A0A1X0NJL1	Trypanosomatidae	82%	99%
A0A3Q8IET6	Leishmania donovani	94%	100%
A0A3R7NIB1	Trypanosoma rangeli	84%	99%
A0B560	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	32%	100%
A1RSE6	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	31%	100%
A3MXZ2	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	34%	100%
A4FWF4	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	33%	98%
A4IAS5	Leishmania infantum	94%	100%
A5ULN4	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	33%	100%
A6VGV1	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	35%	98%
A7I9N4	Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)	33%	100%
A8MB78	Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)	32%	100%
A9A9U8	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	35%	98%
B1YC27	Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta)	31%	100%
B8GDW0	Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)	29%	100%
C5A206	Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3)	29%	100%
C6A1G2	Thermococcus sibiricus (strain DSM 12597 / MM 739)	28%	100%
D0A2D2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	87%	99%
D0A2D3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	87%	91%
E9AEK1	Leishmania major	94%	100%
E9B5R2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	94%	100%
O27127	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	35%	100%
O28389	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	33%	100%
O48558	Zea mays	65%	93%
O49884	Lupinus luteus	59%	93%
O74018	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	30%	100%
P0DJ59	Tetrahymena thermophila (strain SB210)	52%	100%
P11522	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	33%	100%
P14025	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	36%	99%
P14120	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	51%	99%
P29160	Thermococcus celer	30%	100%
P38664	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	49%	99%
P39095	Leishmania major	92%	100%
P49153	Trypanosoma brucei brucei	87%	99%
P52808	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	61%	95%
P54061	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	32%	95%
P58372	Ictalurus punctatus	62%	90%
P58374	Branchiostoma belcheri	60%	91%
P58375	Spodoptera frugiperda	62%	92%
P58376	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	28%	98%
P62888	Homo sapiens	62%	90%
P62889	Mus musculus	62%	90%
P62890	Rattus norvegicus	62%	90%
P67883	Gallus gallus	62%	90%
P67884	Ophiophagus hannah	62%	90%
Q2FPJ8	Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)	35%	100%
Q2NEK6	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	33%	100%
Q3T0D5	Bos taurus	62%	90%
Q55BS9	Dictyostelium discoideum	59%	93%
Q5I7K9	Triticum aestivum	56%	93%
Q5JE35	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	30%	100%
Q6C4U7	Yarrowia lipolytica (strain CLIB 122 / E 150)	48%	95%
Q6FXZ0	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	52%	99%
Q6LXI6	Methanococcus maripaludis (strain S2 / LL)	35%	100%
Q752U5	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	51%	99%
Q76KA2	Macaca fascicularis	62%	90%
Q7S7F1	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	53%	95%
Q8PUR3	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	30%	100%
Q8TRB9	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	30%	100%
Q8TXJ0	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	35%	95%
Q8U0M6	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	32%	100%
Q8VZ19	Arabidopsis thaliana	61%	93%
Q8ZYQ6	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	33%	100%
Q980R3	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	30%	96%
Q9C8F7	Arabidopsis thaliana	60%	93%
Q9LSA3	Arabidopsis thaliana	59%	93%
Q9M5M6	Euphorbia esula	60%	93%
Q9SDG6	Oryza sativa subsp. japonica	65%	94%
Q9UTP0	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	61%	89%
Q9V112	Pyrococcus abyssi (strain GE5 / Orsay)	30%	100%
Q9YAU3	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	35%	100%